The use of SNP markers for cattle breed identification
In this study, using chosen marker selection methods and genotypic data obtained with the use of Illumina Bovine SNP50 BeadChip for individuals belonging to ten cattle breeds, the reduced panels containing the most informative SNP markers were developed. The suitability of selected SNP panels for the effective and reliable assignment of the studied individuals to the breed of origin was checked by three allocation algorithms implemented in GeneClass 2. The studied breeds set included both Polish-native breeds under the genetic resources conservation programs and highly productive breeds with a global range. For all of the ...
Source: J Appl Genet - April 3, 2024 Category: Genetics & Stem Cells Authors: Igor Jasielczuk Artur Gurgul Tomasz Szmato ła Anna Radko Anna Majewska Ewa Sosin Zygmunt Litwi ńczuk Dominika Rubi ś Tomasz Z ąbek Source Type: research
Comparing Bayesian models for the genetic evaluation of oocytes and embryo counts in Dairy Gir cattle
This study aimed to compare and discuss the genetic evaluation for oocyte and embryo counts considering Gaussian (untransformed variable - LIN; transformed by logarithm - LOG; transformed by Anscombe - ANS) and Poisson (POI) distributions. The data comprised 11,343 total oocytes (TO), viable oocytes (VO), cleaved embryos (CE), and viable embryo (VE) records of ovum pick-up from 1740 Dairy Gir heifers and cows. The genetic parameters and breeding values were estimated by the MCMCglmm package of the R software. The posterior means of heritability varied from 0.40 (LIN) to 0.49 (POI) for TO, 0.39 (LIN) to 0.49 (POI) for VO, 0...
Source: J Appl Genet - April 3, 2024 Category: Genetics & Stem Cells Authors: Giovani Luis Feltes Gabriel Soares Campos Fernanda Santos Silva Raidan Luiz Fernando Rodrigues Feres Virg ínia Mara Pereira Ribeiro Jaime Ara újo Cobuci Source Type: research
ZNF26-Associated Genes as Prognostic Signatures in Colorectal Cancer with Broad Therapeutic Implications
J Appl Genet. 2024 Apr 3. doi: 10.1007/s13353-024-00854-3. Online ahead of print.ABSTRACTThe identification of biomarkers correlated with colorectal cancer (CRC) prognosis holds substantial importance from both clinical and scientific perspectives. Zinc finger protein 26 (ZNF26) has not been previously investigated or documented in solid tumors; thus, further research is necessary to ascertain its prognostic value in CRC. Gene expression profiles and clinicopathological data were acquired from The Cancer Genome Atlas (TCGA) database. Subsequently, expression correlation was assessed utilizing the TCGA CRC cohort. The progn...
Source: J Appl Genet - April 3, 2024 Category: Genetics & Stem Cells Authors: Xue Lei Lijia Zhang Ye Liu Heng Sun Jun Yan Songjiang Liu Source Type: research
The use of SNP markers for cattle breed identification
In this study, using chosen marker selection methods and genotypic data obtained with the use of Illumina Bovine SNP50 BeadChip for individuals belonging to ten cattle breeds, the reduced panels containing the most informative SNP markers were developed. The suitability of selected SNP panels for the effective and reliable assignment of the studied individuals to the breed of origin was checked by three allocation algorithms implemented in GeneClass 2. The studied breeds set included both Polish-native breeds under the genetic resources conservation programs and highly productive breeds with a global range. For all of the ...
Source: J Appl Genet - April 3, 2024 Category: Genetics & Stem Cells Authors: Igor Jasielczuk Artur Gurgul Tomasz Szmato ła Anna Radko Anna Majewska Ewa Sosin Zygmunt Litwi ńczuk Dominika Rubi ś Tomasz Z ąbek Source Type: research
Comparing Bayesian models for the genetic evaluation of oocytes and embryo counts in Dairy Gir cattle
This study aimed to compare and discuss the genetic evaluation for oocyte and embryo counts considering Gaussian (untransformed variable - LIN; transformed by logarithm - LOG; transformed by Anscombe - ANS) and Poisson (POI) distributions. The data comprised 11,343 total oocytes (TO), viable oocytes (VO), cleaved embryos (CE), and viable embryo (VE) records of ovum pick-up from 1740 Dairy Gir heifers and cows. The genetic parameters and breeding values were estimated by the MCMCglmm package of the R software. The posterior means of heritability varied from 0.40 (LIN) to 0.49 (POI) for TO, 0.39 (LIN) to 0.49 (POI) for VO, 0...
Source: J Appl Genet - April 3, 2024 Category: Genetics & Stem Cells Authors: Giovani Luis Feltes Gabriel Soares Campos Fernanda Santos Silva Raidan Luiz Fernando Rodrigues Feres Virg ínia Mara Pereira Ribeiro Jaime Ara újo Cobuci Source Type: research
ZNF26-Associated Genes as Prognostic Signatures in Colorectal Cancer with Broad Therapeutic Implications
J Appl Genet. 2024 Apr 3. doi: 10.1007/s13353-024-00854-3. Online ahead of print.ABSTRACTThe identification of biomarkers correlated with colorectal cancer (CRC) prognosis holds substantial importance from both clinical and scientific perspectives. Zinc finger protein 26 (ZNF26) has not been previously investigated or documented in solid tumors; thus, further research is necessary to ascertain its prognostic value in CRC. Gene expression profiles and clinicopathological data were acquired from The Cancer Genome Atlas (TCGA) database. Subsequently, expression correlation was assessed utilizing the TCGA CRC cohort. The progn...
Source: J Appl Genet - April 3, 2024 Category: Genetics & Stem Cells Authors: Xue Lei Lijia Zhang Ye Liu Heng Sun Jun Yan Songjiang Liu Source Type: research
The use of SNP markers for cattle breed identification
In this study, using chosen marker selection methods and genotypic data obtained with the use of Illumina Bovine SNP50 BeadChip for individuals belonging to ten cattle breeds, the reduced panels containing the most informative SNP markers were developed. The suitability of selected SNP panels for the effective and reliable assignment of the studied individuals to the breed of origin was checked by three allocation algorithms implemented in GeneClass 2. The studied breeds set included both Polish-native breeds under the genetic resources conservation programs and highly productive breeds with a global range. For all of the ...
Source: J Appl Genet - April 3, 2024 Category: Genetics & Stem Cells Authors: Igor Jasielczuk Artur Gurgul Tomasz Szmato ła Anna Radko Anna Majewska Ewa Sosin Zygmunt Litwi ńczuk Dominika Rubi ś Tomasz Z ąbek Source Type: research
Comparing Bayesian models for the genetic evaluation of oocytes and embryo counts in Dairy Gir cattle
This study aimed to compare and discuss the genetic evaluation for oocyte and embryo counts considering Gaussian (untransformed variable - LIN; transformed by logarithm - LOG; transformed by Anscombe - ANS) and Poisson (POI) distributions. The data comprised 11,343 total oocytes (TO), viable oocytes (VO), cleaved embryos (CE), and viable embryo (VE) records of ovum pick-up from 1740 Dairy Gir heifers and cows. The genetic parameters and breeding values were estimated by the MCMCglmm package of the R software. The posterior means of heritability varied from 0.40 (LIN) to 0.49 (POI) for TO, 0.39 (LIN) to 0.49 (POI) for VO, 0...
Source: J Appl Genet - April 3, 2024 Category: Genetics & Stem Cells Authors: Giovani Luis Feltes Gabriel Soares Campos Fernanda Santos Silva Raidan Luiz Fernando Rodrigues Feres Virg ínia Mara Pereira Ribeiro Jaime Ara újo Cobuci Source Type: research
Correction to: Unjustly forgotten scientist Wac ław Mayzel (1847-1916)-co‑discoverer of somatic mitosis
J Appl Genet. 2024 Apr 1. doi: 10.1007/s13353-024-00863-2. Online ahead of print.NO ABSTRACTPMID:38558174 | DOI:10.1007/s13353-024-00863-2 (Source: J Appl Genet)
Source: J Appl Genet - April 1, 2024 Category: Genetics & Stem Cells Authors: Janusz Limon Ewa Bartnik Janusz Komender Source Type: research
Correction to: Unjustly forgotten scientist Wac ław Mayzel (1847-1916)-co‑discoverer of somatic mitosis
J Appl Genet. 2024 Apr 1. doi: 10.1007/s13353-024-00863-2. Online ahead of print.NO ABSTRACTPMID:38558174 | DOI:10.1007/s13353-024-00863-2 (Source: J Appl Genet)
Source: J Appl Genet - April 1, 2024 Category: Genetics & Stem Cells Authors: Janusz Limon Ewa Bartnik Janusz Komender Source Type: research
Investigation of mutation spectrum amongst patients with familial primary cardiomyopathy using targeted NGS in Indian population
J Appl Genet. 2024 Mar 29. doi: 10.1007/s13353-024-00855-2. Online ahead of print.ABSTRACTGenetic cardiomyopathies (CM) are disorders that affect morphology and function of cardiac muscle. Significant number of genes have been implicated in causing the phenotype. It is one of the leading genetic causes of death in young. We performed a study to understand the genetic variants in primary cardiomyopathies in an Indian cohort. Study comprised of 22 probands (13 with family history) representing hypertrophic (n = 10), dilated (n = 7), restrictive (n = 2) and arrhythmogenic ventricular(n = 3) cardiomyopathies. Genomic DNA was t...
Source: J Appl Genet - March 29, 2024 Category: Genetics & Stem Cells Authors: Saroja Mysore Krishnaswamy Gautham Arunachal Kumar Gautam Singh Viji Samuel Thomson Paul George Sudha Rao Sumita Danda Source Type: research
Investigation of mutation spectrum amongst patients with familial primary cardiomyopathy using targeted NGS in Indian population
J Appl Genet. 2024 Mar 29. doi: 10.1007/s13353-024-00855-2. Online ahead of print.ABSTRACTGenetic cardiomyopathies (CM) are disorders that affect morphology and function of cardiac muscle. Significant number of genes have been implicated in causing the phenotype. It is one of the leading genetic causes of death in young. We performed a study to understand the genetic variants in primary cardiomyopathies in an Indian cohort. Study comprised of 22 probands (13 with family history) representing hypertrophic (n = 10), dilated (n = 7), restrictive (n = 2) and arrhythmogenic ventricular(n = 3) cardiomyopathies. Genomic DNA was t...
Source: J Appl Genet - March 29, 2024 Category: Genetics & Stem Cells Authors: Saroja Mysore Krishnaswamy Gautham Arunachal Kumar Gautam Singh Viji Samuel Thomson Paul George Sudha Rao Sumita Danda Source Type: research
Investigation of mutation spectrum amongst patients with familial primary cardiomyopathy using targeted NGS in Indian population
J Appl Genet. 2024 Mar 29. doi: 10.1007/s13353-024-00855-2. Online ahead of print.ABSTRACTGenetic cardiomyopathies (CM) are disorders that affect morphology and function of cardiac muscle. Significant number of genes have been implicated in causing the phenotype. It is one of the leading genetic causes of death in young. We performed a study to understand the genetic variants in primary cardiomyopathies in an Indian cohort. Study comprised of 22 probands (13 with family history) representing hypertrophic (n = 10), dilated (n = 7), restrictive (n = 2) and arrhythmogenic ventricular(n = 3) cardiomyopathies. Genomic DNA was t...
Source: J Appl Genet - March 29, 2024 Category: Genetics & Stem Cells Authors: Saroja Mysore Krishnaswamy Gautham Arunachal Kumar Gautam Singh Viji Samuel Thomson Paul George Sudha Rao Sumita Danda Source Type: research
Investigation of mutation spectrum amongst patients with familial primary cardiomyopathy using targeted NGS in Indian population
J Appl Genet. 2024 Mar 29. doi: 10.1007/s13353-024-00855-2. Online ahead of print.ABSTRACTGenetic cardiomyopathies (CM) are disorders that affect morphology and function of cardiac muscle. Significant number of genes have been implicated in causing the phenotype. It is one of the leading genetic causes of death in young. We performed a study to understand the genetic variants in primary cardiomyopathies in an Indian cohort. Study comprised of 22 probands (13 with family history) representing hypertrophic (n = 10), dilated (n = 7), restrictive (n = 2) and arrhythmogenic ventricular(n = 3) cardiomyopathies. Genomic DNA was t...
Source: J Appl Genet - March 29, 2024 Category: Genetics & Stem Cells Authors: Saroja Mysore Krishnaswamy Gautham Arunachal Kumar Gautam Singh Viji Samuel Thomson Paul George Sudha Rao Sumita Danda Source Type: research
Long non-coding RNA variability in porcine skeletal muscle
In this study, we characterised the inter-individual variability of lncRNAs in pigs, in the context of number, length and expression. Transcriptomes collected from muscle tissue belonging to six Polish Landrace boars (PL1-PL6), including half-brothers (PL1-PL3), were investigated using bioinformatics (lncRNA identification and functional analysis) and statistical (lncRNA variability) methods. The number of lncRNA ranged from 1289 to 3500 per animal, and the total number of common lncRNAs among all boars was 232. The number, length and expression of lncRNAs significantly varied between individuals, and no consistent pattern...
Source: J Appl Genet - March 28, 2024 Category: Genetics & Stem Cells Authors: Bart łomiej Hofman Joanna Szyda Magdalena Fr ąszczak Magda Mielczarek Source Type: research
