Immunopharmacology and Immunotoxicology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Eosinophil to lymphocyte ratio may predict OCS reduction and change in quality of life (AQLQ) resulting from asthma biological treatment
CONCLUSIONS: Pre-treatment eosinophil-to-lymphocyte ratio may predict oral corticosteroid dose reduction resulting from omalizumab treatment and change in quality of life and asthma control resulting from anti-IL-5 and IL-5R treatment.PMID:38151952 | DOI:10.1080/08923973.2023.2300300 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - December 28, 2023 Category: Allergy & Immunology Authors: Olga Branicka Rados ław Gawlik Joanna Gl ück Source Type: research

Hydroxychloroquine ameliorates immune functionality and intestinal flora disorders of IgA nephropathy by inhibition of C1GALT1/Cosmc pathway
Conclusion: HCQ diminishes IgA aberrant glycosylation levels, ameliorates renal and intestinal histopathological damage, and attenuates intestinal flora disorders and immune dysfunction in IgAN rats by means of activating the C1GALT1/Cosmc pathway.PMID:38151955 | DOI:10.1080/08923973.2023.2300306 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - December 28, 2023 Category: Allergy & Immunology Authors: Chaochao Wang Xiaoqiao Cai Shengfen Lin Yongqiang Lin Source Type: research

AFM < sub > 1 < /sub > Exposure in Male Balb/c Mice and Intervention Strategies Against Its Immuno-physiological toxicity using Clay Mineral and Lactic Acid Bacteria Alone or in Combination
CONCLUSION: In summary, the LR and/or BT was able to reduce the biochemical, histopathological and immunological damages induced by AFM1 and indeed it could be exploited as one of the biological strategies for food and feedstuffs detoxification.PMID:38151925 | DOI:10.1080/08923973.2023.2300299 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - December 28, 2023 Category: Allergy & Immunology Authors: Amina Aloui Jalila Ben Salah-Abb ès Hela Belgacem Haifa Dhif Abdellah Zinedine Amar Riba Jean Christophe Meile Noel Durande Catherine Brabet Samir Abb ès Source Type: research

Endoplasmic reticulum stress is upregulated in inflammatory bowel disease and contributed TLR2 pathway-mediated inflammatory response
This study investigated whether Thapsigargin (TG) -induced ER protein expression levels contributed to TLR2-mediated inflammatory response. The expression of TLRs was detected via polymerase chain reaction (PCR) in THP-1 cells treated by ERS agonist Thapsigargin (TG). According to the findings, TG could promote TLR2 and TLR5 expression. Subsequently, in TLR2 agonist Pam3CSK4 induced THP-1 cells, TG could lead to increased expression of the inflammatory factors such as TNF-α, IL-1β and IL-8, and ERS inhibitor (TUDCA) could block this effect. However, Pam3CSK4 did not significantly impact the GRP78 and CHOP expression. Bas...
Source: Immunopharmacology and Immunotoxicology - December 26, 2023 Category: Allergy & Immunology Authors: Weijie Wu Yan Zhao Tian Hu Yan Long Ya Zeng Mengling Li Siyuan Peng Jinyue Hu Yueming Shen Source Type: research