Hydroxychloroquine ameliorates immune functionality and intestinal flora disorders of IgA nephropathy by inhibition of C1GALT1/Cosmc pathway

Conclusion: HCQ diminishes IgA aberrant glycosylation levels, ameliorates renal and intestinal histopathological damage, and attenuates intestinal flora disorders and immune dysfunction in IgAN rats by means of activating the C1GALT1/Cosmc pathway.PMID:38151955 | DOI:10.1080/08923973.2023.2300306
Source: Immunopharmacology and Immunotoxicology - Category: Allergy & Immunology Authors: Source Type: research