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Hemolysis Risk Low With Lupus Drug (CME/CE)
(MedPage Today) -- Hydroxychloroquine not tied to hemolytic anemia in certain patients (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 6, 2017 Category: Primary Care Source Type: news

Triple Therapy More Cost-Effective Than MTX + Biologic in RA Triple Therapy More Cost-Effective Than MTX + Biologic in RA
Switching patients with MTX-resistant RA to triple-drug therapy (methotrexate, hydroxychloroquine, sulfasalazine) was recommended before changing to more expensive biologic therapy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 30, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Concern Raised About High Hydroxychloroquine Dosing Concern Raised About High Hydroxychloroquine Dosing
Ophthalmologists'guidance on safe doses for hydroxychloroquine was not followed for approximately half of rheumatology patients treated with hydroxychloroquine, a new study showed.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 15, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Plaquenil (Hydroxychloroquine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 10, 2017 Category: Drugs & Pharmacology Source Type: news

New Guidelines for Hydroxychloroquine Visual Screening New Guidelines for Hydroxychloroquine Visual Screening
With increasing and broader use of hydroxychloroquine, more patients are in need of ongoing screening for retinal toxicity.Medscape Optometry (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 11, 2016 Category: Consumer Health News Tags: Commentary Source Type: news

Hydroxychloroquine, abatacept linked with reduced type 2 diabetes
LONDON – U.S. rheumatoid arthritis patients had a significantly reduced incidence of type 2 diabetes when on treatment with either hydroxychloroquine or abatacept in an analysis of more than 13,000... (Source: Clinical Endocrinology News)
Source: Clinical Endocrinology News - June 10, 2016 Category: Endocrinology Source Type: news

Triple Therapy With Methotrexate Effective, Cheaper in RATriple Therapy With Methotrexate Effective, Cheaper in RA
The combination of methotrexate, sulphasalazine, and hydroxychloroquine is similar in effect as methotrexate plus biologic therapy for patients with rheumatoid arthritis (RA), according to a new network meta-analysis. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 27, 2016 Category: Consumer Health News Tags: Rheumatology News Source Type: news

New Lyme Disease Study Reveals Strong Reporting Bias
This study is a useful contribution to ongoing investigations of how to treat ongoing Lyme disease symptoms among patients who have received the standard 28-day course of doxycycline and continue to experience severe symptoms commonly associated with Lyme disease. This study is also significant because, unlike the majority of Lyme disease-related studies published in peer-reviewed medical journals, it made international headlines in mainstream news outlets. Some publications that specialize in medical and health-related stories covered the story appropriately, such as Medscape, whose headline reads, "Post-Treatment Ly...
Source: Healthy Living - The Huffington Post - April 8, 2016 Category: Consumer Health News Source Type: news

RheumNow: Hydroxychloroquine Blood Levels in SLE
(MedPage Today) -- Guidelines on dosing this drug can be confusing (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 3, 2016 Category: Primary Care Source Type: news

Retinal Thickness Changes and Hydroxychloroquine-related RetinopathyRetinal Thickness Changes and Hydroxychloroquine-related Retinopathy
Changes in the inner and outer retinal layer do not reliably signal the development of retinopathy in patients taking hydroxychloroquine (HCQ), according to a retrospective study. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 25, 2016 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Research makes advances to treat osteoarthritis pain
For the 8.8 million people in the UK with osteoarthritis, research into new treatments to tackle osteoarthritis pain has the potential to dramatically improve quality of life. That’s why supporting innovative research in this area is one of our priorities, accounting for 25% of our research funding. We asked Dr Fiona Watt, consultant rheumatologist and senior clinical research fellow at our Centre for Osteoarthritis Pathogenesis at the Kennedy Institute of Rheumatology in Oxford, to share some of the latest developments: “Most of the patients who walk through the door to my clinic want to know how I can help t...
Source: Arthritis Research UK - March 10, 2016 Category: Rheumatology Source Type: news

ACR: Actual-weight hydroxychloroquine dosing works in SLE, up to a point
SAN FRANCISCO – Hydroxychloroquine (Plaquenil) dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus (SLE), according to a review of... (Source: Skin and Allergy News)
Source: Skin and Allergy News - December 30, 2015 Category: Dermatology Source Type: news

Plaquenil Benefits Fetus in Lupus Pregnancy (CME/CE)
(MedPage Today) -- Preterm birth and intrauterine growth restriction decreased with hydroxychloroquine (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - July 6, 2015 Category: OBGYN Source Type: news

Hydroxychloroquine Not Effective in Hand OsteoarthritisHydroxychloroquine Not Effective in Hand Osteoarthritis
For patients with symptomatic osteoarthritis of the hand, pain and functional outcomes were no different whether they were treated with hydroxychloroquine or placebo for 24 weeks. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 1, 2015 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Early nonadherence ups emergency care, hospitalization for lupus
Systemic lupus erythematosus patients who have just started drug therapy are at greater risk for needing acute care and possible hospitalization if they are nonadherent, based on an analysis of U.S. Medicaid beneficiaries. Data on 9,600 new hydroxychloroquine (HCQ) and 3,829 new oral...googletag.display('div-gpt-ad-cta'); (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 22, 2015 Category: Dermatology Tags: IMN News IMN Rheumatology RHEUM News RHEUM Lupus/Connective Tissue Diseases SAN Clinical News SAN News FPN News Source Type: news

Patients with primary hand osteoarthritis should not be prescribed hydroxychloroquine, study suggests
The results of an interventional trial showed that use of the disease-modifying anti-rheumatic drug hydroxychloroquine for 24 weeks did not diminish mild-moderate pain from primary hand osteoarthritis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 13, 2015 Category: Science Source Type: news

Patients with primary hand OA should not be prescribed hydroxychloroquine
(European League Against Rheumatism) The results of an interventional trial presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) showed that use of the disease-modifying anti-rheumatic drug hydroxychloroquine for 24 weeks did not diminish mild-moderate pain from primary hand osteoarthritis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 13, 2015 Category: Global & Universal Source Type: news

Malaria drug to be repurposed for the heart
Hydroxychloroquine found to reduce heart rate significantly in ‘chance observation’ (Source: The Irish Times - Health)
Source: The Irish Times - Health - May 21, 2015 Category: Consumer Health News Source Type: news

Malaria Drug Has Utility in RA (CME/CE)
(MedPage Today) -- Hydroxychloroquine less likely to cause hyperlipidemia than methotrexate. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - April 11, 2015 Category: Cardiology Source Type: news

Just How Common Is Hydroxychloroquine Retinopathy?Just How Common Is Hydroxychloroquine Retinopathy?
Addressing an ongoing debate, a new study seeks clarity about the prevalence of this treatment-induced condition, as well as its leading risk factors. Medscape Optometry (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - April 8, 2015 Category: Drugs & Pharmacology Tags: Viewpoint Source Type: news

Effect of Hydroxychloroquine on Glucose and Lipid MetabolismEffect of Hydroxychloroquine on Glucose and Lipid Metabolism
Can this antimalarial agent improve glucose and lipid parameters? Read about a case with surprising results. Therapeutic Advances in Endocrinology and Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 14, 2014 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

hydroxychloroquine
Title: hydroxychloroquineCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 10/28/2014 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - October 28, 2014 Category: Rheumatology Source Type: news

Significant Retinopathy Risk With Long-Term HydroxychloroquineSignificant Retinopathy Risk With Long-Term Hydroxychloroquine
Long-term use of hydroxychloroquine may carry a significant risk of toxic retinopathy, according to a retrospective case-control study. Reuters Health Information (Source: Medscape Ophthalmology Headlines)
Source: Medscape Ophthalmology Headlines - October 15, 2014 Category: Opthalmology Tags: Ophthalmology News Source Type: news

Common drug for Sjögren’s does not help symptoms
Hydroxychloroquine didn’t reduce dryness, pain or fatigue more than placebo Related items from OnMedicaNewer RA drugs no better than old in keeping patients at workThyroid patients need better monitoringDrugs regulators “put profits before patients”Lupus anticoagulant greatly raises stroke risk (Source: OnMedica Latest News)
Source: OnMedica Latest News - July 17, 2014 Category: UK Health Source Type: news

Sjogren's: Hydroxychloroquine No Better Than Placebo Sjogren's: Hydroxychloroquine No Better Than Placebo
The commonly prescribed agent did not relieve symptoms of dryness, fatigue, or pain in a randomized controlled trial, but efficacy criteria may have been too tough, investigators say. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 15, 2014 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Hydroxychloroquine for Tamoxifen Resistance in Breast CancerHydroxychloroquine for Tamoxifen Resistance in Breast Cancer
The antimalarial drug hydroxychloroquine overcomes breast cancer resistance to tamoxifen, according to preclinical studies of estrogen receptor-positive (ER+) mammary tumors. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 23, 2014 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Screen for Hydroxychloroquine Retinopathy to Preserve VisionScreen for Hydroxychloroquine Retinopathy to Preserve Vision
Hydroxychloroquine retinopathy can cause damage that may continue for 3 or more years after the drug is discontinued and greatly reduce the amount of visual loss. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 13, 2014 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Tamoxifen-resistant breast cancer reversed when drug paired with anti-malaria agent
The inexpensive anti-malarial drug hydroxychloroquine reverses resistance to tamoxifen, a widely used breast cancer drug, in mice. “Tamoxifen resistance when treating breast cancer is a big issue in the clinic, and we believe our findings provide a very promising fix to the problem,” says the study’s senior investigator. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 13, 2014 Category: Science Source Type: news

Tamoxifen-resistant breast cancer reversed when drug paired with anti-malaria agent
(Georgetown University Medical Center) The inexpensive anti-malarial drug hydroxychloroquine reverses resistance to tamoxifen, a widely used breast cancer drug, in mice. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 13, 2014 Category: Cancer & Oncology Source Type: news

Block autophagy in multiple cancers: Trials show promise
The malaria drug hydroxychloroquine blocked autophagy in a host of aggressive cancers -- glioblastoma, melanoma, lymphoma and myeloma, renal and colon cancers -- and in some cases helped stabilize disease. These results come from the largest group of results to date, and show promise for the treatment of cancer in the future. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 22, 2014 Category: Science Source Type: news

Clinical trials designed to block autophagy in multiple cancers show promise
(University of Pennsylvania School of Medicine) In the largest group of results to date, researchers from Penn Medicine's Abramson Cancer Center and other institutions have shown in clinical trials that the malaria drug hydroxychloroquine blocked autophagy in a host of aggressive cancers -- glioblastoma, melanoma, lymphoma and myeloma, renal and colon cancers -- and in some cases helped stabilize disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 22, 2014 Category: Cancer & Oncology Source Type: news

Visual Field Test Catches Some HCQ Retinopathy Missed by OCTVisual Field Test Catches Some HCQ Retinopathy Missed by OCT
Spectral-domain optical coherence tomography without visual field test misses nearly 10% of hydroxychloroquine retinopathy scotomas. Medscape Medical News (Source: Medscape Ophthalmology Headlines)
Source: Medscape Ophthalmology Headlines - February 5, 2014 Category: Opthalmology Tags: Ophthalmology News Source Type: news

Hydroxychloroquine-associated hyperpigmentation mimicking elder abuse - Cohen PR.
BACKGROUND: Hydroxychloroquine may result in cutaneous dyschromia. Older individuals who are the victims of elder abuse can present with bruising and resolving ecchymoses. PURPOSE: The features of hydroxychloroquine-associated hyperpigmentation are describ... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - December 15, 2013 Category: Global & Universal Tags: Age: Elder Adults Source Type: news

Mircoperimetric Sensitivity in Patients on Plaquenil TherapyMircoperimetric Sensitivity in Patients on Plaquenil Therapy
Chronic hydroxychloroquine therapy can cause irreversible retinal toxicity and possibly result in vision loss. Can microperimetry provide enough information about visual function in these patients? Eye (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 8, 2013 Category: Consumer Health News Tags: Ophthalmology Journal Article Source Type: news

Anxiety, depression and suicidal ideation in patients with rheumatoid arthritis in use of methotrexate, hydroxychloroquine, leflunomide and biological drugs - Pinho de Oliveira Ribeiro N, Rafael de Mello Schier A, Ornelas AC, Pinho de Oliveira CM, Nardi AE, Silva AC.
OBJECTIVE: This paper aims to investigate the prevalence of anxiety, depression and suicidal ideation in patients with rheumatoid arthritis taking different drugs to control the disease. METHODS: The study included 105 patients with rheumatoid arthritis wh... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - July 14, 2013 Category: Global & Universal Tags: Suicide and Self-Harm Source Type: news

Vitamin D for Refractory Immune ThrombocytopeniaVitamin D for Refractory Immune Thrombocytopenia
This article reports on two cases of patients with severe immune thrombocytopenic purpura who responded to high-dose vitamin D and hydroxychloroquine after conventional therapies failed. Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 26, 2013 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news