Remdesivir, hydroxychloroquine show no antiviral effect against COVID-19: Study
The study, published in the journal Annals of Internal Medicine, evaluated the effects of the two drugs on all-cause, in-hospital mortality, the degree of respiratory failure and inflammation, and viral clearance in the oropharynx. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 13, 2021 Category: Pharmaceuticals Source Type: news

Neither remdesivir NOR hydroxychloroquine lower the risk of respiratory failure in COVID-19 patients
A new study from Oslo University Hospital, in Norway, found that neither remdesivir nor hydroxychloroquine reduced respiratory failure or lowered inflammation in COVID-19 patients. (Source: the Mail online | Health)
Source: the Mail online | Health - July 12, 2021 Category: Consumer Health News Source Type: news

Hydroxychloroquine, remdesivir fail to improve COVID-19 patient outcomes in WHO-led study
Neither remdesivir nor hydroxychloroquine boosts recovery in patients hospitalized with COVID-19, according to a study led by the World Health Organization, and published by the Annals of Internal Medicine. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 12, 2021 Category: Consumer Health News Source Type: news

Neither remdesivir nor HCQ affect viral clearance in hospitalized patients with COVID-19
(American College of Physicians) NOR-Solidarity, an independent, add-on, randomized controlled trial to the World Health Organization (WHO) Solidarity trial, found that neither remdesivir nor hydroxychloroquine (HCQ) affected viral clearance in hospitalized patients with COVID-19. The WHO Solidarity trial showed no effect of remdesivir or hydroxychloroquine (HCQ) on mortality but did not assess antiviral effects of these drugs. The findings are published in Annals of Internal Medicine. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 12, 2021 Category: Infectious Diseases Source Type: news

Chloroquine and Hydroxychloroquine Use During Pregnancy Chloroquine and Hydroxychloroquine Use During Pregnancy
Chloroquine and hydroxychloroquine are used in the treatment of rheumatic conditions, but are they safe to use during pregnancy? A new study examines the possible fetal effects.Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 23, 2021 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Most drugs for treating adult Covid patients not recommended for kids: Government guidelines
About the treatment of children, the guidelines by the Union Health Ministry said most drugs used in adults such as ivermectin, hydroxychloroquine, favipiravir and antibiotics such as doxycycline or azithromycin have not been tested on children for prevention or treatment of Covid infection among them. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - June 16, 2021 Category: Pharmaceuticals Source Type: news

Mitigating the impacts of COVID-19: where are the mental health trials?, Lancet Psychiatry
COVID-19 prompted rapid mobilisation of health services and medical science in the face of unprecedented challenges. When COVID-19 emerged in 2020, medical science delivered, and delivered quickly. Using large-scale multicentre trials, researchers in partnership with health services established the ability of cheap and scalable interventions (such as corticosteroids) to save lives, and rapidly showed the futility of anecdotally endorsed repurposed drugs (such as hydroxychloroquine). The effectiveness of vaccinations was quickly established in phase 2 and 3 trials, providing the confidence to roll out successful vaccine pro...
Source: Current Awareness Service for Health (CASH) - June 4, 2021 Category: Consumer Health News Source Type: news

Coronavirus live news: Britain records 2,694 new Covid cases; Dominic Cummings criticises government over lockdowns
Germany to bar visitors from UK over Covid variants of concern; sewage samplesbeing tested across Englandto monitor Covid variantsMore than 50m Covid vaccine doses given in EnglandScientist faces legal action for challenging hydroxychloroquine studyNepal calls new elections amid worsening Covid outbreakBrazil: Bolsonaro never wanted vaccines, says senatorSee all our coronavirus coverage7.28pmBSTMore than 35,000 Roman Catholic pilgrims flocked to an open-air shrine in Romania for a centuries-old procession that had been previously cancelled last year due to the pandemic.AP reports, The service in Sumuleu Ciuc, located in Ro...
Source: Guardian Unlimited Science - May 22, 2021 Category: Science Authors: Edna Mohamed (now) and Clea Skopeliti , Nadeem Badshah (earlier) Tags: Coronavirus Infectious diseases Medical research Microbiology Science World news Source Type: news

World expert in scientific misconduct faces legal action for challenging integrity of hydroxychloroquine study
Australian and international scientists publish open letter defending Dr Elisabeth Bik and calling for science whistleblowers to be protected (Source: Reuters: Health)
Source: Reuters: Health - May 22, 2021 Category: Consumer Health News Source Type: news

Anthony Fauci, 100 Days Into the Biden Administration, Is Finally Getting to Do His Job
When Dr. Anthony Fauci arrived at 1600 Pennsylvania Ave. for his first White House press briefing under the new Biden Administration, he could see things would be different. It was the day after the Inauguration, and President Joe Biden was eager to get the country’s COVID-19 response back on track. Five minutes before he addressed the public, Fauci spoke with the new President. “He said, ‘I want you to just go and tell the science, explain to people that if we make mistakes, we’re going to fix the mistakes and we’re not going to dwell on the mistakes. Let science be communicated to the public...
Source: TIME: Health - May 18, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

Major differences in COVID patient care caused by insufficient data, misleading advice
While there was extensive use of drug repurposing throughout the first 10 months of the COVID-19 pandemic, there was substantial heterogeneity over the types of drugs used for treatment purposes globally. Some drugs, including hydroxychloroquine, saw sharp declines in use, while adjunctive therapies grew into a more relied upon method for patient management. (Source: World Pharma News)
Source: World Pharma News - May 12, 2021 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Prophylaxis against covid-19: living systematic review and network meta-analysis, BMJ
Review (11 RCT ' s) found hydroxychloroquine prophylaxis has trivial to no effect on hospital admission and mortality, probably increases adverse effects and probably does not reduce risk of COVID; it is highly uncertain ivermectin with iota-carrageenan or alone reduces infection risk. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 28, 2021 Category: Consumer Health News Source Type: news

COVID-19 Prolongs QT Interval Independent of Other Factors COVID-19 Prolongs QT Interval Independent of Other Factors
COVID-19 infection can prolong corrected QTc in hospitalized patients, even in the absence of hydroxychloroquine and azithromycin treatment.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - April 26, 2021 Category: Cardiology Tags: Cardiology News Source Type: news

Contested effects and chaotic policies: the 2020 story of (hydroxy) chloroquine for treating COVID19, Cochrane Library
Cochrane Review by Bhagteshwar Singh and colleagues definitively concludes that hydroxychloroquine has no clinical benefit in treating COVID ‐19 in hospitalized patients. 2 External 0 0 0 [ false https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.ED000151/full#ED000151-bib-0001 true false%> 2 External 0 0 0 1 false https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.ED000151/full#ED000151-bib-0001 true false%>] The dissemination of information on these drugs in the scientific press and other media has been rapid and tumultuous with strong and polarized opinions among scientists, politicians, and the genera...
Source: Current Awareness Service for Health (CASH) - April 1, 2021 Category: Consumer Health News Source Type: news

Hydroxychloroquine valid option in autoantibody-negative rheumatoid arthritis
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - April 1, 2021 Category: Drugs & Pharmacology Source Type: news