Talk Evidence - evidence in Roe vs Wade, MI treatment variation, and tribal methodologies
Helen Macdonald, The BMJ's research integrity editor is back with another episode, and this week is joined by Joe Ross, professor of medicine and public health at Yale, and US research editor for The BMJ, and Juan Franco, editor in chief of BMJ EBM, and Professor at the Instituto Universitario Hospital Italiano de Buenos Aires In this episode they discuss; The US supreme court looks set to overturn Roe v Wade, creating a patchwork of abortion provision across the U.S. We consider the role which evidence might play in documenting how health is affected by that decision, and whether medical evidence is being used at all i...
Source: The BMJ Podcast - May 23, 2022 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Talk Evidence - evidence in Roe vs Wade, MI treatment variation, and tribal methodologies
Helen Macdonald, The BMJ's research integrity editor is back with another episode, and this week is joined by Joe Ross, professor of medicine and public health at Yale, and US research editor for The BMJ, and Juan Franco, editor in chief of BMJ EBM, and Professor at the Instituto Universitario Hospital Italiano de Buenos Aires In this episode they discuss; The US supreme court looks set to overturn Roe v Wade, creating a patchwork of abortion provision across the U.S. We consider the role which evidence might play in documenting how health is affected by that decision, and whether medical evidence is being used at all in...
Source: The BMJ Podcast - May 23, 2022 Category: General Medicine Authors: BMJ Group Source Type: podcasts

Coronapod: Ivermectin, what the science says
Ivermectin is a cheap, widely available, anti-parasitic drug that has been proposed by many as a possible treatment for COVID-19. Dozens of trials have been started, but results have been far from clear, with inconsistent results further confused by high profile paper retractions. Nonetheless many countries have recommended the use of Ivermectin, despite WHO advice to the contrary.Now a group of researchers have found suspect data in another influential paper which claimed a Ivermectin caused a 90% reduction in fatality. The paper, published at the end of 2020, has since been withdrawn pending investigation. In this episod...
Source: Nature Podcast - August 6, 2021 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 755: COVID-19 clinical update #62 with Dr. Daniel Griffin
In COVID-19 clinical update #62, Daniel Griffin covers outdoor transmission of the virus, safe use of NSAIDS, expansion of Pfizer/BioNTech vaccine to include 12-15 year olds, post-disease Mucormycosis, and hydroxychloroquine treatment associated with increased mortality. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Moderna vaccine safe, effective in teens (AAP news) Review of outdoor transmission (JID) Pfizer/BioNTech vaccine EUA 12-15 year olds (FDA) NSAIDS safe in COVID-19 (Lancet Rheum) Post-COVID black fungus ...
Source: This Week in Virology - MP3 Edition - May 15, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 715: Fauci ouchy
TWiV explains why hydroxychloroquine failed in humans despite showing antiviral effects in cells, and reviews the published data on the Pfizer/BioNTech mRNA vaccine. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode TMPRSS2 is why hydroxychloroquine failed (PLoS Path) Safety and efficacy of BNT162b2 mRNA vaccine (NEJM) Letters read on TWiV 715 Timestamps by Jolene. Thanks! Weekly Picks Brianne – How the Body Reacts to Viruses Rich – How do wombats poop cubes? Kathy – The Verse by the ...
Source: This Week in Virology - MP3 Edition - February 4, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 673: Wake up and smell the pandemic
Daniel Griffin provides a clinical report on COVID-19, we debunk the Great Barrington Declaration, and discuss smell and taste changes as early indicators of the pandemic, vascular disease and thrombosis in SARS-CoV-2 infected humans and rhesus macaques, and the ability of the swine pathogen SADS-CoV to infect human respiratory tract cells. Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Daniel’s COVID-19 testing strategy calculator (and medRxiv preprint) US COVID-19 mortality rates (JAMA) Final remdesivir report (NEJM) Hydroxychloroquine for COVID-19 (NEJM) Te...
Source: This Week in Virology - MP3 Edition - October 18, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

COVID-19 Vaccine Approval and the FDA
Hydroxychloroquine and convalescent plasma approvals by the FDA under Emergency Use Authorization (EUA) protocols have raised concerns the agency is under withering political pressure to fast-track a COVID-19 vaccine before it is proven safe and effective. Joshua Sharfstein, MD, Johns Hopkins Bloomberg School of Public Health, and JAMA Associate Editor Preeti Malani, MD, University of Michigan, discuss implications for public health and policy responses to ensure vaccine safety. Recorded September 18, 2020. Related Article: Reassuring the Public and Clinical Community About the Scientific Review and Approval of a COVID-19 ...
Source: JAMA Author Interviews - September 23, 2020 Category: General Medicine Authors: JAMA Network Source Type: podcasts

TWiV 647: Testing is our way out of this crisis
In this mid-week TWiV, children under 10 do transmit SARS-CoV-2, why hydroxychloroquine does not work for treating COVID-19, scale-up of diagnostic testing, explanation of LAMP testing, and listener questions. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Children do transmit infection (Emerg Inf Dis) NIH RADx initiative (NEJM) Rockefeller Foundation testing plan HCQ observational study (Int J Inf Dis) Can't kill HCQ (Science Based Medicine) HCQ does not inhibit SARS-CoV-2 in human lung cells (Nature) ...
Source: This Week in Virology - MP3 Edition - July 30, 2020 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Talk Evidence covid-19 update - surgisphere data, and protests in a pandemic
This week, we ’re asking questions about surgisphere data, and how it might have got into such high impact journals, we’re also talking about the protests around the world about structural racism - and how they intersect with the covid pandemic. (1.39) Helen and Carl talk about the data underlying the newly retracted papers on hydroxychloroquine and ace-inhibitors or ARBs and covid. (7.45) Fiona Godlee, the BMJ’s editor in chief, comes onto the pod to talk about retractions, and why they’re often called for, an rarely done. (25.10) We talk about the protests, and Carl gives us his opinion on the risk of covid tr...
Source: The BMJ Podcast - June 12, 2020 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts

Talk Evidence covid-19 update - surgisphere data, and protests in a pandemic
This week, we’re asking questions about surgisphere data, and how it might have got into such high impact journals, we’re also talking about the protests around the world about structural racism - and how they intersect with the covid pandemic. (1.39) Helen and Carl talk about the data underlying the newly retracted papers on hydroxychloroquine and ace-inhibitors or ARBs and covid. (7.45) Fiona Godlee, the BMJ’s editor in chief, comes onto the pod to talk about retractions, and why they’re often called for, an rarely done. (25.10) We talk about the protests, and Carl gives us his opinion on the risk of covid tra...
Source: The BMJ Podcast - June 12, 2020 Category: General Medicine Authors: BMJ Group Source Type: podcasts

Coronapod: The Surgisphere scandal that rocked coronavirus drug research
In this episode:00:52 Testing disparitiesAs testing capacities increase, it is clear that not everyone has equal access. But grassroots organisations are trying to correct this inequity. We hear about one researcher’s fight to get testing to those below the poverty line in California.09:04 The hydroxychloroquine saga continuesAs a high profile study in the Lancet is retracted, the first data from clinical trials is coming in and it is not encouraging. We discuss the murky future of hydroxychloroquine as a COVID drug.News: High-profile coronavirus retractions raise concerns about data oversight12:31 Will the Surgisph...
Source: Nature Podcast - June 12, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Coronapod: The Surgisphere scandal that rocked coronavirus drug research
In this episode:00:52 Testing disparitiesAs testing capacities increase, it is clear that not everyone has equal access. But grassroots organisations are trying to correct this inequity. We hear about one researcher’s fight to get testing to those below the poverty line in California.09:04 The hydroxychloroquine saga continuesAs a high profile study in the Lancet is retracted, the first data from clinical trials is coming in and it is not encouraging. We discuss the murky future of hydroxychloroquine as a COVID drug.News: High-profile coronavirus retractions raise concerns about data oversight12:31 Will the Surgisph...
Source: Nature Podcast - June 12, 2020 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Talk evidence covid-19 update - second wave and care home failings
In this episode of Talk Evidence, we'll be finding out if second waves are inevitable (or even a thing), how the UK's failure to protect it's care homes is symbolic of a neglected part of public life, and why those papers on hydroxychloroquine were retracted. This is Talk Evidence - the podcast for evidence based medicine, where research, guidance and practice are debated and demystified. Helen Macdonald, UK research editor for The BMJ, and Carl Heneghan, professor of EBM at the University of Oxford and editor of BMJ EBM, talk about some of the latest developments in the world of evidence, and what they mean. This week...
Source: The BMJ Podcast - June 8, 2020 Category: General Medicine Authors: BMJ talk medicine Source Type: podcasts