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Forkhead box A1 induces angiogenesis through activation of the S100A8/p38 MAPK axis in cutaneous wound healing
CONCLUSION: FOXA1 mediates the phosphorylation of p38 MAPK through transcription activation of S100A8, thereby inducing angiogenesis and promoting cutaneous wound healing.PMID:37459395 | DOI:10.1080/08923973.2023.2233693 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - July 17, 2023 Category: Allergy & Immunology Authors: Zhongzhi Zhou Meilin Zou Hongping Chen Furong Zhu Tingting Wang Xinling Huang Source Type: research

Leukoreduced PRP enhanced proliferation and ECM production yet inhibited senescence, inflammation, and multi-differentiation potential of AFSCs by downregulating HMGB1
CONCLUSION: Leukoreduced PRP promotes cell proliferation and ECM production of AFSCs, while inhibiting their senescence, inflammation, and multi-differentiation potentials via downregulating HMGB1 expression.PMID:37436160 | DOI:10.1080/08923973.2023.2232106 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - July 12, 2023 Category: Allergy & Immunology Authors: Baoshan Hu Lianxin Wang Naikun Sun Gang Rui Shengrong Lin Source Type: research

Astragaloside IV restores Th17/Treg balance via inhibiting CXCR4 to improve chronic obstructive pulmonary disease
CONCLUSIONS: AS-IV restores Th17/Treg balance via impeding CXCR4 to ameliorate COPD.PMID:37417915 | DOI:10.1080/08923973.2023.2228479 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - July 7, 2023 Category: Allergy & Immunology Authors: Xiulian Zhang Xueliang Li Wei Ma Fangying Liu Pinxian Huang Lei Wei Li Li Yechang Qian Source Type: research

CD26 CAR-T cells have attenuated mitochondrial and glycolytic metabolic profiling
CONCLUSION: CD26 CAR-T cells showed distinctive metabolic profiling during expansion that was extremely unfavorable to cell persistence and function. These findings may provide new insights for the optimization of CD26 CAR-T cells in terms of metabolism.PMID:37382435 | DOI:10.1080/08923973.2023.2231632 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - June 29, 2023 Category: Allergy & Immunology Authors: Xiaoying Zhu Zhaodong Zhong Fankai Meng Ping Zou Yong You Qing Li Xiaojian Zhu Source Type: research