Expression of calcitonin gene-related peptide in atopic dermatitis and correlation with distress
CONCLUSIONS: CGRP may have a role in both the inflammatory process and distress, in AD.PMID:37676055 | DOI:10.1080/08923973.2023.2253988 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - September 7, 2023 Category: Allergy & Immunology Authors: Saly Abdelhadi Klas Nordlind Bj örn Johansson Elvar Theodorsson Mikael Holst Louise L önndahl Source Type: research

Withaferin A suppressed hepatocellular carcinoma progression through inducing IGF2BP3/FOXO1/JAK2/STAT3 pathway-mediated ROS production
Conclusions: WA-induced ROS inhibited HCC cell growth and migration through the inhibition of IGF2BP3 to deactivate JAK2/STAT3 signaling, resulting in increased FOXO1 expression to further stimulate ROS production and inhibit JAK2/STAT3 signaling.PMID:37671837 | DOI:10.1080/08923973.2023.2247552 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - September 6, 2023 Category: Allergy & Immunology Authors: Jinhai Li Mengchen Ge Pengcheng Deng Xinquan Wu Longqing Shi Yu Yang Source Type: research

Leptin/lipopolysaccharide-treated dendritic cell vaccine improved cellular immune responses in an animal model of breast cancer
CONCLUSION: Compared to the Leptin-treated mDC and LPS-treated mDC vaccines, the Leptin/LPS-treated mDC vaccine was more effective in inhibiting BC development and boosting immune responses against tumor.PMID:37647347 | DOI:10.1080/08923973.2023.2253989 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - August 30, 2023 Category: Allergy & Immunology Authors: Pedram Basirjafar Raziyeh Zandvakili Javad Masoumi Nahid Zainodini Zahra Taghipour Hossein Khorramdelazad Soheila Yousefi Tayyebeh Tavakoli Mahboobeh Vatanparast Sepehr Safdel Mahsa Gheitasi Fatemeh Ayoobi Bahar Naseri Abdollah Jafarzadeh Source Type: research

Icariin decreases cell proliferation and inflammation of rheumatoid arthritis-fibroblast like synoviocytes via GAREM1/MAPK signaling pathway
Conclusion: Our findings suggest that icariin treatment can alleviate the development of RA by reducing cell proliferation and inflammation in RA-FLS through the regulation of the GAREM1/MAPK signaling pathway. These results support the potential of icariin as a therapeutic agent for RA treatment. As icariin is safe and well-tolerated in previous studies, further research is warranted to explore its efficacy in clinical settings.PMID:37647355 | DOI:10.1080/08923973.2023.2253990 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - August 30, 2023 Category: Allergy & Immunology Authors: Zhiming Wu Qin Liu Zhengliu Cao Hui Li Yifen Zhou Peng Zhang Source Type: research

Leptin/lipopolysaccharide-treated dendritic cell vaccine improved cellular immune responses in an animal model of breast cancer
CONCLUSION: Compared to the Leptin-treated mDC and LPS-treated mDC vaccines, the Leptin/LPS-treated mDC vaccine was more effective in inhibiting BC development and boosting immune responses against tumor.PMID:37647347 | DOI:10.1080/08923973.2023.2253989 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - August 30, 2023 Category: Allergy & Immunology Authors: Pedram Basirjafar Raziyeh Zandvakili Javad Masoumi Nahid Zainodini Zahra Taghipour Hossein Khorramdelazad Soheila Yousefi Tayyebeh Tavakoli Mahboobeh Vatanparast Sepehr Safdel Mahsa Gheitasi Fatemeh Ayoobi Bahar Naseri Abdollah Jafarzadeh Source Type: research

Icariin decreases cell proliferation and inflammation of rheumatoid arthritis-fibroblast like synoviocytes via GAREM1/MAPK signaling pathway
Conclusion: Our findings suggest that icariin treatment can alleviate the development of RA by reducing cell proliferation and inflammation in RA-FLS through the regulation of the GAREM1/MAPK signaling pathway. These results support the potential of icariin as a therapeutic agent for RA treatment. As icariin is safe and well-tolerated in previous studies, further research is warranted to explore its efficacy in clinical settings.PMID:37647355 | DOI:10.1080/08923973.2023.2253990 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - August 30, 2023 Category: Allergy & Immunology Authors: Zhiming Wu Qin Liu Zhengliu Cao Hui Li Yifen Zhou Peng Zhang Source Type: research

Leptin/lipopolysaccharide-treated dendritic cell vaccine improved cellular immune responses in an animal model of breast cancer
CONCLUSION: Compared to the Leptin-treated mDC and LPS-treated mDC vaccines, the Leptin/LPS-treated mDC vaccine was more effective in inhibiting BC development and boosting immune responses against tumor.PMID:37647347 | DOI:10.1080/08923973.2023.2253989 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - August 30, 2023 Category: Allergy & Immunology Authors: Pedram Basirjafar Raziyeh Zandvakili Javad Masoumi Nahid Zainodini Zahra Taghipour Hossein Khorramdelazad Soheila Yousefi Tayyebeh Tavakoli Mahboobeh Vatanparast Sepehr Safdel Mahsa Gheitasi Fatemeh Ayoobi Bahar Naseri Abdollah Jafarzadeh Source Type: research

Icariin decreases cell proliferation and inflammation of rheumatoid arthritis-fibroblast like synoviocytes via GAREM1/MAPK signaling pathway
Conclusion Our findings suggest that icariin treatment can alleviate development of RA by reducing cell proliferation and inflammation in RA-FLS through the regulation of the GAREM1/MAPK signaling pathway. These results support the potential of icariin as a therapeutic agent for RA treatment. As icariin has been shown to be safe and well-tolerated in previous studies, further research is warranted to explore its efficacy in clinical settings.PMID:37647355 | DOI:10.1080/08923973.2023.2253990 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - August 30, 2023 Category: Allergy & Immunology Authors: Zhiming Wu Qin Liu Zhengliu Cao Hui Li Yifen Zhou Peng Zhang Source Type: research

Leptin/lipopolysaccharide-treated dendritic cell vaccine improved cellular immune responses in an animal model of breast cancer
CONCLUSION: Compared to the Leptin-treated mDC and LPS-treated mDC vaccines, the Leptin/LPS-treated mDC vaccine was more effective in inhibiting BC development and boosting immune responses against tumor.PMID:37647347 | DOI:10.1080/08923973.2023.2253989 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - August 30, 2023 Category: Allergy & Immunology Authors: Pedram Basirjafar Raziyeh Zandvakili Javad Masoumi Nahid Zainodini Zahra Taghipour Hossein Khorramdelazad Soheila Yousefi Tayyebeh Tavakoli Mahboobeh Vatanparast Sepehr Safdel Mahsa Gheitasi Fatemeh Ayoobi Bahar Naseri Abdollah Jafarzadeh Source Type: research

Icariin decreases cell proliferation and inflammation of rheumatoid arthritis-fibroblast like synoviocytes via GAREM1/MAPK signaling pathway
Conclusion Our findings suggest that icariin treatment can alleviate development of RA by reducing cell proliferation and inflammation in RA-FLS through the regulation of the GAREM1/MAPK signaling pathway. These results support the potential of icariin as a therapeutic agent for RA treatment. As icariin has been shown to be safe and well-tolerated in previous studies, further research is warranted to explore its efficacy in clinical settings.PMID:37647355 | DOI:10.1080/08923973.2023.2253990 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - August 30, 2023 Category: Allergy & Immunology Authors: Zhiming Wu Qin Liu Zhengliu Cao Hui Li Yifen Zhou Peng Zhang Source Type: research

Leptin/lipopolysaccharide-treated dendritic cell vaccine improved cellular immune responses in an animal model of breast cancer
CONCLUSION: Compared to the Leptin-treated mDC and LPS-treated mDC vaccines, the Leptin/LPS-treated mDC vaccine was more effective in inhibiting BC development and boosting immune responses against tumor.PMID:37647347 | DOI:10.1080/08923973.2023.2253989 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - August 30, 2023 Category: Allergy & Immunology Authors: Pedram Basirjafar Raziyeh Zandvakili Javad Masoumi Nahid Zainodini Zahra Taghipour Hossein Khorramdelazad Soheila Yousefi Tayyebeh Tavakoli Mahboobeh Vatanparast Sepehr Safdel Mahsa Gheitasi Fatemeh Ayoobi Bahar Naseri Abdollah Jafarzadeh Source Type: research

Icariin decreases cell proliferation and inflammation of rheumatoid arthritis-fibroblast like synoviocytes via GAREM1/MAPK signaling pathway
Conclusion Our findings suggest that icariin treatment can alleviate development of RA by reducing cell proliferation and inflammation in RA-FLS through the regulation of the GAREM1/MAPK signaling pathway. These results support the potential of icariin as a therapeutic agent for RA treatment. As icariin has been shown to be safe and well-tolerated in previous studies, further research is warranted to explore its efficacy in clinical settings.PMID:37647355 | DOI:10.1080/08923973.2023.2253990 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - August 30, 2023 Category: Allergy & Immunology Authors: Zhiming Wu Qin Liu Zhengliu Cao Hui Li Yifen Zhou Peng Zhang Source Type: research

Effects of erucin on inflammatory mediators and antioxidant enzymes' expression in TNF- α-stimulated human oral epithelial cells
Conclusions: These results suggest that erucin may provide a new anti-inflammatory agent that can be used in the treatment of periodontitis.PMID:37624680 | DOI:10.1080/08923973.2023.2250551 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - August 25, 2023 Category: Allergy & Immunology Authors: Masahiro Shimoyama Yoshitaka Hosokawa Ikuko Hosokawa Kazumi Ozaki Keiichi Hosaka Source Type: research