Role of G-protein-coupled estrogen receptor in the pathogenesis of chronic asthma
CONCLUSION: G-1 administration suppressed allergic airway inflammation in mice with chronic OVA asthma. GPER may be a potential therapeutic target for chronic allergic asthma.PMID:38142780 | DOI:10.1016/j.imlet.2023.12.001 (Source: Immunology Letters)
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Masamichi Itoga Yoshiko Ishioka Tomonori Makiguchi Hisashi Tanaka Kageaki Taima Norihiro Saito Hirofumi Tomita Sadatomo Tasaka Source Type: research
Adenine is an anti-inflammatory metabolite found to be more abundant in M-CSF over GM-CSF-differentiated human macrophages
Immunol Lett. 2023 Dec 22:S0165-2478(23)00204-3. doi: 10.1016/j.imlet.2023.12.003. Online ahead of print.ABSTRACTImmunometabolism has been unveiled in the last decade to play a major role in controlling macrophage metabolism and inflammation. There has been a constant effort to understand the immunomodulating properties of regulated metabolites during inflammation with the aim of controlling and re-wiring aberrant macrophages in inflammatory diseases. M-CSF and GM-CSF-differentiated macrophages play a key role in mounting successful innate immune responses. When a resolution phase is not achieved however, GM-CSF macrophage...
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Karl J Harber Thuc-Anh Nguyen Bauke V Schomakers Daan A F Heister Helga E de Vries Michel van Weeghel Jan Van den Bossche Menno P J de Winther Source Type: research
Role of G-protein-coupled estrogen receptor in the pathogenesis of chronic asthma
CONCLUSION: G-1 administration suppressed allergic airway inflammation in mice with chronic OVA asthma. GPER may be a potential therapeutic target for chronic allergic asthma.PMID:38142780 | DOI:10.1016/j.imlet.2023.12.001 (Source: Immunology Letters)
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Masamichi Itoga Yoshiko Ishioka Tomonori Makiguchi Hisashi Tanaka Kageaki Taima Norihiro Saito Hirofumi Tomita Sadatomo Tasaka Source Type: research
Adenine is an anti-inflammatory metabolite found to be more abundant in M-CSF over GM-CSF-differentiated human macrophages
Immunol Lett. 2023 Dec 22:S0165-2478(23)00204-3. doi: 10.1016/j.imlet.2023.12.003. Online ahead of print.ABSTRACTImmunometabolism has been unveiled in the last decade to play a major role in controlling macrophage metabolism and inflammation. There has been a constant effort to understand the immunomodulating properties of regulated metabolites during inflammation with the aim of controlling and re-wiring aberrant macrophages in inflammatory diseases. M-CSF and GM-CSF-differentiated macrophages play a key role in mounting successful innate immune responses. When a resolution phase is not achieved however, GM-CSF macrophage...
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Karl J Harber Thuc-Anh Nguyen Bauke V Schomakers Daan A F Heister Helga E de Vries Michel van Weeghel Jan Van den Bossche Menno P J de Winther Source Type: research
Role of G-protein-coupled estrogen receptor in the pathogenesis of chronic asthma
CONCLUSION: G-1 administration suppressed allergic airway inflammation in mice with chronic OVA asthma. GPER may be a potential therapeutic target for chronic allergic asthma.PMID:38142780 | DOI:10.1016/j.imlet.2023.12.001 (Source: Immunology Letters)
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Masamichi Itoga Yoshiko Ishioka Tomonori Makiguchi Hisashi Tanaka Kageaki Taima Norihiro Saito Hirofumi Tomita Sadatomo Tasaka Source Type: research
Adenine is an anti-inflammatory metabolite found to be more abundant in M-CSF over GM-CSF-differentiated human macrophages
Immunol Lett. 2023 Dec 22:S0165-2478(23)00204-3. doi: 10.1016/j.imlet.2023.12.003. Online ahead of print.ABSTRACTImmunometabolism has been unveiled in the last decade to play a major role in controlling macrophage metabolism and inflammation. There has been a constant effort to understand the immunomodulating properties of regulated metabolites during inflammation with the aim of controlling and re-wiring aberrant macrophages in inflammatory diseases. M-CSF and GM-CSF-differentiated macrophages play a key role in mounting successful innate immune responses. When a resolution phase is not achieved however, GM-CSF macrophage...
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Karl J Harber Thuc-Anh Nguyen Bauke V Schomakers Daan A F Heister Helga E de Vries Michel van Weeghel Jan Van den Bossche Menno P J de Winther Source Type: research
Role of G-protein-coupled estrogen receptor in the pathogenesis of chronic asthma
CONCLUSION: G-1 administration suppressed allergic airway inflammation in mice with chronic OVA asthma. GPER may be a potential therapeutic target for chronic allergic asthma.PMID:38142780 | DOI:10.1016/j.imlet.2023.12.001 (Source: Immunology Letters)
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Masamichi Itoga Yoshiko Ishioka Tomonori Makiguchi Hisashi Tanaka Kageaki Taima Norihiro Saito Hirofumi Tomita Sadatomo Tasaka Source Type: research
Adenine is an anti-inflammatory metabolite found to be more abundant in M-CSF over GM-CSF-differentiated human macrophages
Immunol Lett. 2023 Dec 22:S0165-2478(23)00204-3. doi: 10.1016/j.imlet.2023.12.003. Online ahead of print.ABSTRACTImmunometabolism has been unveiled in the last decade to play a major role in controlling macrophage metabolism and inflammation. There has been a constant effort to understand the immunomodulating properties of regulated metabolites during inflammation with the aim of controlling and re-wiring aberrant macrophages in inflammatory diseases. M-CSF and GM-CSF-differentiated macrophages play a key role in mounting successful innate immune responses. When a resolution phase is not achieved however, GM-CSF macrophage...
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Karl J Harber Thuc-Anh Nguyen Bauke V Schomakers Daan A F Heister Helga E de Vries Michel van Weeghel Jan Van den Bossche Menno P J de Winther Source Type: research
Role of G-protein-coupled estrogen receptor in the pathogenesis of chronic asthma
CONCLUSION: G-1 administration suppressed allergic airway inflammation in mice with chronic OVA asthma. GPER may be a potential therapeutic target for chronic allergic asthma.PMID:38142780 | DOI:10.1016/j.imlet.2023.12.001 (Source: Immunology Letters)
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Masamichi Itoga Yoshiko Ishioka Tomonori Makiguchi Hisashi Tanaka Kageaki Taima Norihiro Saito Hirofumi Tomita Sadatomo Tasaka Source Type: research
Adenine is an anti-inflammatory metabolite found to be more abundant in M-CSF over GM-CSF-differentiated human macrophages
Immunol Lett. 2023 Dec 22:S0165-2478(23)00204-3. doi: 10.1016/j.imlet.2023.12.003. Online ahead of print.ABSTRACTImmunometabolism has been unveiled in the last decade to play a major role in controlling macrophage metabolism and inflammation. There has been a constant effort to understand the immunomodulating properties of regulated metabolites during inflammation with the aim of controlling and re-wiring aberrant macrophages in inflammatory diseases. M-CSF and GM-CSF-differentiated macrophages play a key role in mounting successful innate immune responses. When a resolution phase is not achieved however, GM-CSF macrophage...
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Karl J Harber Thuc-Anh Nguyen Bauke V Schomakers Daan A F Heister Helga E de Vries Michel van Weeghel Jan Van den Bossche Menno P J de Winther Source Type: research
Role of G-protein-coupled estrogen receptor in the pathogenesis of chronic asthma
CONCLUSION: G-1 administration suppressed allergic airway inflammation in mice with chronic OVA asthma. GPER may be a potential therapeutic target for chronic allergic asthma.PMID:38142780 | DOI:10.1016/j.imlet.2023.12.001 (Source: Immunology Letters)
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Masamichi Itoga Yoshiko Ishioka Tomonori Makiguchi Hisashi Tanaka Kageaki Taima Norihiro Saito Hirofumi Tomita Sadatomo Tasaka Source Type: research
Adenine is an anti-inflammatory metabolite found to be more abundant in M-CSF over GM-CSF-differentiated human macrophages
Immunol Lett. 2023 Dec 22:S0165-2478(23)00204-3. doi: 10.1016/j.imlet.2023.12.003. Online ahead of print.ABSTRACTImmunometabolism has been unveiled in the last decade to play a major role in controlling macrophage metabolism and inflammation. There has been a constant effort to understand the immunomodulating properties of regulated metabolites during inflammation with the aim of controlling and re-wiring aberrant macrophages in inflammatory diseases. M-CSF and GM-CSF-differentiated macrophages play a key role in mounting successful innate immune responses. When a resolution phase is not achieved however, GM-CSF macrophage...
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Karl J Harber Thuc-Anh Nguyen Bauke V Schomakers Daan A F Heister Helga E de Vries Michel van Weeghel Jan Van den Bossche Menno P J de Winther Source Type: research
Role of G-protein-coupled estrogen receptor in the pathogenesis of chronic asthma
CONCLUSION: G-1 administration suppressed allergic airway inflammation in mice with chronic OVA asthma. GPER may be a potential therapeutic target for chronic allergic asthma.PMID:38142780 | DOI:10.1016/j.imlet.2023.12.001 (Source: Immunology Letters)
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Masamichi Itoga Yoshiko Ishioka Tomonori Makiguchi Hisashi Tanaka Kageaki Taima Norihiro Saito Hirofumi Tomita Sadatomo Tasaka Source Type: research
Adenine is an anti-inflammatory metabolite found to be more abundant in M-CSF over GM-CSF-differentiated human macrophages
Immunol Lett. 2023 Dec 22:S0165-2478(23)00204-3. doi: 10.1016/j.imlet.2023.12.003. Online ahead of print.ABSTRACTImmunometabolism has been unveiled in the last decade to play a major role in controlling macrophage metabolism and inflammation. There has been a constant effort to understand the immunomodulating properties of regulated metabolites during inflammation with the aim of controlling and re-wiring aberrant macrophages in inflammatory diseases. M-CSF and GM-CSF-differentiated macrophages play a key role in mounting successful innate immune responses. When a resolution phase is not achieved however, GM-CSF macrophage...
Source: Immunology Letters - December 24, 2023 Category: Allergy & Immunology Authors: Karl J Harber Thuc-Anh Nguyen Bauke V Schomakers Daan A F Heister Helga E de Vries Michel van Weeghel Jan Van den Bossche Menno P J de Winther Source Type: research
CD36 as a double-edged sword in cancer
Immunol Lett. 2023 Dec 19;265:7-15. doi: 10.1016/j.imlet.2023.12.002. Online ahead of print.ABSTRACTThe membrane protein CD36 is a lipid transporter, scavenger receptor, and receptor for the antiangiogenic protein thrombospondin 1 (TSP1). CD36 is expressed by cancer cells and by many associated cells including various cancer-infiltrating immune cell types. Thereby, CD36 plays critical roles in cancer, and it has been reported to affect cancer growth, metastasis, angiogenesis, and drug resistance. However, these roles are partly contradictory, as CD36 has been both reported to promote and inhibit cancer progression. Moreove...
Source: Immunology Letters - December 20, 2023 Category: Allergy & Immunology Authors: Muwei Jiang Renske Karsenberg Frans Bianchi Geert van den Bogaart Source Type: research
