Disturbance in the reconstitution of distinct T-cell subsets and the incidence of GvHD following allo-HSCT in pediatric patients with non-malignant hematological disorders
CONCLUSION: Our findings suggest a possible relationship between the influence of acute GvHD and its prevention on delayed CD4 T-cell reconstitution and, reciprocally, unbalanced regeneration of CD4 and CD8 T-cell subsets in the development of chronic GvHD.PMID:37474024 | DOI:10.1016/j.imlet.2023.07.008 (Source: Immunology Letters)
Source: Immunology Letters - July 20, 2023 Category: Allergy & Immunology Authors: Shideh Namazi Bayegi Amir Ali Hamidieh Maryam Behfar Mahmood Bozorgmehr Amene Saghazadeh Nader Tajik Ali-Akbar Delbandi Farzaneh Tofighi Zavareh Samaneh Delavari Mehdi Shekarabi Nima Rezaei Source Type: research
Disturbance in the reconstitution of distinct T-cell subsets and the incidence of GvHD following allo-HSCT in pediatric patients with non-malignant hematological disorders
CONCLUSION: Our findings suggest a possible relationship between the influence of acute GvHD and its prevention on delayed CD4 T-cell reconstitution and, reciprocally, unbalanced regeneration of CD4 and CD8 T-cell subsets in the development of chronic GvHD.PMID:37474024 | DOI:10.1016/j.imlet.2023.07.008 (Source: Immunology Letters)
Source: Immunology Letters - July 20, 2023 Category: Allergy & Immunology Authors: Shideh Namazi Bayegi Amir Ali Hamidieh Maryam Behfar Mahmood Bozorgmehr Amene Saghazadeh Nader Tajik Ali-Akbar Delbandi Farzaneh Tofighi Zavareh Samaneh Delavari Mehdi Shekarabi Nima Rezaei Source Type: research
Disturbance in the reconstitution of distinct T-cell subsets and the incidence of GvHD following allo-HSCT in pediatric patients with non-malignant hematological disorders
CONCLUSION: Our findings suggest a possible relationship between the influence of acute GvHD and its prevention on delayed CD4 T-cell reconstitution and, reciprocally, unbalanced regeneration of CD4 and CD8 T-cell subsets in the development of chronic GvHD.PMID:37474024 | DOI:10.1016/j.imlet.2023.07.008 (Source: Immunology Letters)
Source: Immunology Letters - July 20, 2023 Category: Allergy & Immunology Authors: Shideh Namazi Bayegi Amir Ali Hamidieh Maryam Behfar Mahmood Bozorgmehr Amene Saghazadeh Nader Tajik Ali-Akbar Delbandi Farzaneh Tofighi Zavareh Samaneh Delavari Mehdi Shekarabi Nima Rezaei Source Type: research
Disturbance in the reconstitution of distinct T-cell subsets and the incidence of GvHD following allo-HSCT in pediatric patients with non-malignant hematological disorders
CONCLUSION: Our findings suggest a possible relationship between the influence of acute GvHD and its prevention on delayed CD4 T-cell reconstitution and, reciprocally, unbalanced regeneration of CD4 and CD8 T-cell subsets in the development of chronic GvHD.PMID:37474024 | DOI:10.1016/j.imlet.2023.07.008 (Source: Immunology Letters)
Source: Immunology Letters - July 20, 2023 Category: Allergy & Immunology Authors: Shideh Namazi Bayegi Amir Ali Hamidieh Maryam Behfar Mahmood Bozorgmehr Amene Saghazadeh Nader Tajik Ali-Akbar Delbandi Farzaneh Tofighi Zavareh Samaneh Delavari Mehdi Shekarabi Nima Rezaei Source Type: research
Disturbance in the reconstitution of distinct T-cell subsets and the incidence of GvHD following allo-HSCT in pediatric patients with non-malignant hematological disorders
CONCLUSION: Our findings suggest a possible relationship between the influence of acute GvHD and its prevention on delayed CD4 T-cell reconstitution and, reciprocally, unbalanced regeneration of CD4 and CD8 T-cell subsets in the development of chronic GvHD.PMID:37474024 | DOI:10.1016/j.imlet.2023.07.008 (Source: Immunology Letters)
Source: Immunology Letters - July 20, 2023 Category: Allergy & Immunology Authors: Shideh Namazi Bayegi Amir Ali Hamidieh Maryam Behfar Mahmood Bozorgmehr Amene Saghazadeh Nader Tajik Ali-Akbar Delbandi Farzaneh Tofighi Zavareh Samaneh Delavari Mehdi Shekarabi Nima Rezaei Source Type: research
Disturbance in the reconstitution of distinct T-cell subsets and the incidence of GvHD following allo-HSCT in pediatric patients with non-malignant hematological disorders
CONCLUSION: Our findings suggest a possible relationship between the influence of acute GvHD and its prevention on delayed CD4 T-cell reconstitution and, reciprocally, unbalanced regeneration of CD4 and CD8 T-cell subsets in the development of chronic GvHD.PMID:37474024 | DOI:10.1016/j.imlet.2023.07.008 (Source: Immunology Letters)
Source: Immunology Letters - July 20, 2023 Category: Allergy & Immunology Authors: Shideh Namazi Bayegi Amir Ali Hamidieh Maryam Behfar Mahmood Bozorgmehr Amene Saghazadeh Nader Tajik Ali-Akbar Delbandi Farzaneh Tofighi Zavareh Samaneh Delavari Mehdi Shekarabi Nima Rezaei Source Type: research
Corrigendum to "Interleukin-40 is a promising biomarker associated with type 2 diabetes mellitus risk" [Immunology Letters 254 (2023) 1-5]
Immunol Lett. 2023 Jul 17:S0165-2478(23)00115-3. doi: 10.1016/j.imlet.2023.07.002. Online ahead of print.NO ABSTRACTPMID:37468424 | DOI:10.1016/j.imlet.2023.07.002 (Source: Immunology Letters)
Source: Immunology Letters - July 19, 2023 Category: Allergy & Immunology Authors: Shahad W Nussrat Ali H Ad'hiah Source Type: research
Corrigendum to "Interleukin-40 is a promising biomarker associated with type 2 diabetes mellitus risk" [Immunology Letters 254 (2023) 1-5]
Immunol Lett. 2023 Jul 17:S0165-2478(23)00115-3. doi: 10.1016/j.imlet.2023.07.002. Online ahead of print.NO ABSTRACTPMID:37468424 | DOI:10.1016/j.imlet.2023.07.002 (Source: Immunology Letters)
Source: Immunology Letters - July 19, 2023 Category: Allergy & Immunology Authors: Shahad W Nussrat Ali H Ad'hiah Source Type: research
Distribution of Peripheral Blood Mononuclear Cell Subtypes in Patients with West Syndrome: Impact of Synacthen Treatment
CONCLUSIONS: Our findings lend further support for the involvement of inflammation-related mechanisms in WS. New-onset WS patients are inclined to display increased plasma cells in the peripheral blood. Synacthen treatment does not show a beneficial effect on most effector acquired and innate immunity subsets.PMID:37459957 | DOI:10.1016/j.imlet.2023.07.007 (Source: Immunology Letters)
Source: Immunology Letters - July 17, 2023 Category: Allergy & Immunology Authors: Selen Soylu Minara Cherkezzade Ece Akbay ır Hande Y üceer Korkmaz Gizem Koral Elif Şanlı P ınar Topaloğlu Vuslat Y ılmaz Erdem T üzün Cem İsmail Küçükali Source Type: research
The miR-142 miRNAs: shaping the na ïve immune system
Immunol Lett. 2023 Jul 15:S0165-2478(23)00119-0. doi: 10.1016/j.imlet.2023.07.005. Online ahead of print.ABSTRACTImmunity in a naïve organism is tightly controlled. Adequate proportions of the many immune cell subsets must be produced to mount efficient responses to eventual challenges. In addition, a functioning immune system is highly dynamic at steady state. Mature immune cells must be positioned properly and/or circulate to facilitate the detection of dangers. They must also be poised to promptly react to unusual encounters, while ignoring innocuous germs and self. Numerous regulatory mechanisms act at the molecular l...
Source: Immunology Letters - July 17, 2023 Category: Allergy & Immunology Authors: William J Olson Emmanuel Derudder Source Type: research
Distribution of Peripheral Blood Mononuclear Cell Subtypes in Patients with West Syndrome: Impact of Synacthen Treatment
CONCLUSIONS: Our findings lend further support for the involvement of inflammation-related mechanisms in WS. New-onset WS patients are inclined to display increased plasma cells in the peripheral blood. Synacthen treatment does not show a beneficial effect on most effector acquired and innate immunity subsets.PMID:37459957 | DOI:10.1016/j.imlet.2023.07.007 (Source: Immunology Letters)
Source: Immunology Letters - July 17, 2023 Category: Allergy & Immunology Authors: Selen Soylu Minara Cherkezzade Ece Akbay ır Hande Y üceer Korkmaz Gizem Koral Elif Şanlı P ınar Topaloğlu Vuslat Y ılmaz Erdem T üzün Cem İsmail Küçükali Source Type: research
The miR-142 miRNAs: shaping the na ïve immune system
Immunol Lett. 2023 Jul 15:S0165-2478(23)00119-0. doi: 10.1016/j.imlet.2023.07.005. Online ahead of print.ABSTRACTImmunity in a naïve organism is tightly controlled. Adequate proportions of the many immune cell subsets must be produced to mount efficient responses to eventual challenges. In addition, a functioning immune system is highly dynamic at steady state. Mature immune cells must be positioned properly and/or circulate to facilitate the detection of dangers. They must also be poised to promptly react to unusual encounters, while ignoring innocuous germs and self. Numerous regulatory mechanisms act at the molecular l...
Source: Immunology Letters - July 17, 2023 Category: Allergy & Immunology Authors: William J Olson Emmanuel Derudder Source Type: research
Human toll-like receptor 8 (TLR8) in NK cells: implication for cancer immunotherapy
Immunol Lett. 2023 Jul 12:S0165-2478(23)00116-5. doi: 10.1016/j.imlet.2023.07.003. Online ahead of print.ABSTRACTToll-like receptors (TLR)s are homo- or heterodimeric proteins, whose structure and function were widely described in the antigen presenting cells (APC), such as Dendritic cells (DC). Recently, the expression and the role of TLRs in fighting against pathogens, was described also in NK cells. Their activation and functional properties can be directly and indirectly modulated by agonists for TLRs. In particular CD56bright NK cells subset, that is the most abundant NK cell subset in tissues and tumor microenvironme...
Source: Immunology Letters - July 14, 2023 Category: Allergy & Immunology Authors: Irene Veneziani Claudia Alicata Lorenzo Moretta Enrico Maggi Source Type: research
Epstein-Barr virus and genetic risk variants as determinants of T-bet < sup > + < /sup > B cell-driven autoimmune diseases
Immunol Lett. 2023 Jul 12:S0165-2478(23)00118-9. doi: 10.1016/j.imlet.2023.07.006. Online ahead of print.ABSTRACTB cells expressing the transcription factor T-bet are found to have a protective role in viral infections, but are also considered major players in the onset of different types of autoimmune diseases. Currently, the exact mechanisms driving such 'atypical' memory B cells to contribute to protective immunity or autoimmunity are unclear. In addition to general autoimmune-related factors including sex and age, the ways T-bet+ B cells instigate autoimmune diseases may be determined by the close interplay between gen...
Source: Immunology Letters - July 14, 2023 Category: Allergy & Immunology Authors: Laurens Bogers Kirsten L Kuiper Joost Smolders Jasper Rip Marvin M van Luijn Source Type: research
Human toll-like receptor 8 (TLR8) in NK cells: implication for cancer immunotherapy
Immunol Lett. 2023 Jul 12:S0165-2478(23)00116-5. doi: 10.1016/j.imlet.2023.07.003. Online ahead of print.ABSTRACTToll-like receptors (TLR)s are homo- or heterodimeric proteins, whose structure and function were widely described in the antigen presenting cells (APC), such as Dendritic cells (DC). Recently, the expression and the role of TLRs in fighting against pathogens, was described also in NK cells. Their activation and functional properties can be directly and indirectly modulated by agonists for TLRs. In particular CD56bright NK cells subset, that is the most abundant NK cell subset in tissues and tumor microenvironme...
Source: Immunology Letters - July 14, 2023 Category: Allergy & Immunology Authors: Irene Veneziani Claudia Alicata Lorenzo Moretta Enrico Maggi Source Type: research
