E3 ligase Nedd4L promotes macrophage M1 polarization and exacerbates brain damage by TRAF3/TBK1 signaling pathway after ICH in mice
CONCLUSIONS: Our data demonstrated that Nedd4L was involved in the pathogenesis of ICH, which promoted inflammatory responses and exacerbated brain damage by TRAF3 following ICH.PMID:37940007 | DOI:10.1016/j.imlet.2023.11.002 (Source: Immunology Letters)
Source: Immunology Letters - November 8, 2023 Category: Allergy & Immunology Authors: Xiaohui Xia Zhao Yang Jiangwei Zhang Xiongjie Fu Bin Han Qijiang Xiong Anyong Yu Source Type: research

The European B cell network
Immunol Lett. 2023 Nov 2;264:1-3. doi: 10.1016/j.imlet.2023.11.001. Online ahead of print.NO ABSTRACTPMID:37925058 | DOI:10.1016/j.imlet.2023.11.001 (Source: Immunology Letters)
Source: Immunology Letters - November 4, 2023 Category: Allergy & Immunology Authors: Annemiek B van Spriel Rudi W Hendriks Source Type: research

The European B Cell Network
Immunol Lett. 2023 Nov 2:S0165-2478(23)00181-5. doi: 10.1016/j.imlet.2023.11.001. Online ahead of print.NO ABSTRACTPMID:37925058 | DOI:10.1016/j.imlet.2023.11.001 (Source: Immunology Letters)
Source: Immunology Letters - November 4, 2023 Category: Allergy & Immunology Authors: Annemiek van Spriel Rudi W Hendriks Source Type: research

The European B Cell Network
Immunol Lett. 2023 Nov 2:S0165-2478(23)00181-5. doi: 10.1016/j.imlet.2023.11.001. Online ahead of print.NO ABSTRACTPMID:37925058 | DOI:10.1016/j.imlet.2023.11.001 (Source: Immunology Letters)
Source: Immunology Letters - November 4, 2023 Category: Allergy & Immunology Authors: Annemiek van Spriel Rudi W Hendriks Source Type: research

The European B Cell Network
Immunol Lett. 2023 Nov 2:S0165-2478(23)00181-5. doi: 10.1016/j.imlet.2023.11.001. Online ahead of print.NO ABSTRACTPMID:37925058 | DOI:10.1016/j.imlet.2023.11.001 (Source: Immunology Letters)
Source: Immunology Letters - November 4, 2023 Category: Allergy & Immunology Authors: Annemiek van Spriel Rudi W Hendriks Source Type: research

Activation of cannabinoid receptors 2 alleviates myocardial damage in cecal ligation and puncture-induced sepsis by inhibiting pyroptosis
CONCLUSIONS: CB2 receptor activation has a protective effect on the myocardium of mice with sepsis by inhibiting pyroptosis.PMID:37918639 | DOI:10.1016/j.imlet.2023.10.007 (Source: Immunology Letters)
Source: Immunology Letters - November 2, 2023 Category: Allergy & Immunology Authors: Jingjing Zhang Yali Zhu Shuxian Chen Zujin Xu Bin Zhang Anpeng Liu Qianwen He Jia Zhan Source Type: research

Activation of cannabinoid receptors 2 alleviates myocardial damage in cecal ligation and puncture-induced sepsis by inhibiting pyroptosis
CONCLUSIONS: CB2 receptor activation has a protective effect on the myocardium of mice with sepsis by inhibiting pyroptosis.PMID:37918639 | DOI:10.1016/j.imlet.2023.10.007 (Source: Immunology Letters)
Source: Immunology Letters - November 2, 2023 Category: Allergy & Immunology Authors: Jingjing Zhang Yali Zhu Shuxian Chen Zujin Xu Bin Zhang Anpeng Liu Qianwen He Jia Zhan Source Type: research

Activation of cannabinoid receptors 2 alleviates myocardial damage in cecal ligation and puncture-induced sepsis by inhibiting pyroptosis
CONCLUSIONS: CB2 receptor activation has a protective effect on the myocardium of mice with sepsis by inhibiting pyroptosis.PMID:37918639 | DOI:10.1016/j.imlet.2023.10.007 (Source: Immunology Letters)
Source: Immunology Letters - November 2, 2023 Category: Allergy & Immunology Authors: Jingjing Zhang Yali Zhu Shuxian Chen Zujin Xu Bin Zhang Anpeng Liu Qianwen He Jia Zhan Source Type: research

The SMAC mimetic birinapant alleviates lipopolysaccharide-induced acute lung injury by inhibiting MAPK signaling
In conclusion, the results proved that birinapant protected against LPS-induced ALI through inhibiting MAPK activation and K48-linked ubiquitination of TRAF3 in alveolar macrophages.PMID:37913914 | DOI:10.1016/j.imlet.2023.10.008 (Source: Immunology Letters)
Source: Immunology Letters - November 1, 2023 Category: Allergy & Immunology Authors: Hui Hu Man Ma Tao Li Li Shi Peizhi Li Source Type: research

Macrophage-derived inflammation Promotes Pulmonary Vascular Remodeling in Hypoxia-induced Pulmonary Arterial Hypertension mice
In conclusion, pulmonary artery remodeling in HPH mice worsens progressively in a time-dependent manner, with inflammatory cell infiltration predominating in the early stage and pulmonary vascular remodeling occurring in the later stage.PMID:37875238 | DOI:10.1016/j.imlet.2023.10.005 (Source: Immunology Letters)
Source: Immunology Letters - October 24, 2023 Category: Allergy & Immunology Authors: Hong Liu Yuxiang Wang Qingqing Zhang Chuanchuan Liu Yougang Ma Pan Huang Rili Ge Lan Ma Source Type: research

Thymic atrophy induced by Plasmodium berghei ANKA and Plasmodium yoelii 17XL Infection
Immunol Lett. 2023 Oct 22:S0165-2478(23)00166-9. doi: 10.1016/j.imlet.2023.10.006. Online ahead of print.ABSTRACTThe thymus is the anatomical site where T cells undergo a complex process of differentiation, proliferation, selection, and elimination of autorreactive cells which involves molecular signals in different intrathymic environment. However, the immunological functions of the thymus can be compromised upon exposure to different infections, affecting thymocyte populations. In this work, we investigated the impact of malaria parasites on the thymus by using C57BL/6 mice infected with Plasmodium berghei ANKA and Plasm...
Source: Immunology Letters - October 24, 2023 Category: Allergy & Immunology Authors: G M Corral-Ruiz M J P érez-Vega A Gal án-Salinas I Mancilla-Herrera J Barrios-Pay án L Fabila-Castillo R Hern ández-Pando L E S ánchez-Torres Source Type: research

Macrophage-derived inflammation Promotes Pulmonary Vascular Remodeling in Hypoxia-induced Pulmonary Arterial Hypertension mice
In conclusion, pulmonary artery remodeling in HPH mice worsens progressively in a time-dependent manner, with inflammatory cell infiltration predominating in the early stage and pulmonary vascular remodeling occurring in the later stage.PMID:37875238 | DOI:10.1016/j.imlet.2023.10.005 (Source: Immunology Letters)
Source: Immunology Letters - October 24, 2023 Category: Allergy & Immunology Authors: Hong Liu Yuxiang Wang Qingqing Zhang Chuanchuan Liu Yougang Ma Pan Huang Rili Ge Lan Ma Source Type: research

Thymic atrophy induced by Plasmodium berghei ANKA and Plasmodium yoelii 17XL Infection
Immunol Lett. 2023 Oct 22:S0165-2478(23)00166-9. doi: 10.1016/j.imlet.2023.10.006. Online ahead of print.ABSTRACTThe thymus is the anatomical site where T cells undergo a complex process of differentiation, proliferation, selection, and elimination of autorreactive cells which involves molecular signals in different intrathymic environment. However, the immunological functions of the thymus can be compromised upon exposure to different infections, affecting thymocyte populations. In this work, we investigated the impact of malaria parasites on the thymus by using C57BL/6 mice infected with Plasmodium berghei ANKA and Plasm...
Source: Immunology Letters - October 24, 2023 Category: Allergy & Immunology Authors: G M Corral-Ruiz M J P érez-Vega A Gal án-Salinas I Mancilla-Herrera J Barrios-Pay án L Fabila-Castillo R Hern ández-Pando L E S ánchez-Torres Source Type: research

Macrophage-derived inflammation Promotes Pulmonary Vascular Remodeling in Hypoxia-induced Pulmonary Arterial Hypertension mice
In conclusion, pulmonary artery remodeling in HPH mice worsens progressively in a time-dependent manner, with inflammatory cell infiltration predominating in the early stage and pulmonary vascular remodeling occurring in the later stage.PMID:37875238 | DOI:10.1016/j.imlet.2023.10.005 (Source: Immunology Letters)
Source: Immunology Letters - October 24, 2023 Category: Allergy & Immunology Authors: Hong Liu Yuxiang Wang Qingqing Zhang Chuanchuan Liu Yougang Ma Pan Huang Rili Ge Lan Ma Source Type: research

Thymic atrophy induced by Plasmodium berghei ANKA and Plasmodium yoelii 17XL Infection
Immunol Lett. 2023 Oct 22:S0165-2478(23)00166-9. doi: 10.1016/j.imlet.2023.10.006. Online ahead of print.ABSTRACTThe thymus is the anatomical site where T cells undergo a complex process of differentiation, proliferation, selection, and elimination of autorreactive cells which involves molecular signals in different intrathymic environment. However, the immunological functions of the thymus can be compromised upon exposure to different infections, affecting thymocyte populations. In this work, we investigated the impact of malaria parasites on the thymus by using C57BL/6 mice infected with Plasmodium berghei ANKA and Plasm...
Source: Immunology Letters - October 24, 2023 Category: Allergy & Immunology Authors: G M Corral-Ruiz M J P érez-Vega A Gal án-Salinas I Mancilla-Herrera J Barrios-Pay án L Fabila-Castillo R Hern ández-Pando L E S ánchez-Torres Source Type: research