Immunology and Allergy Clinics of North America This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

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ELSEVIER (Source: Immunology and Allergy Clinics of North America)
Source: Immunology and Allergy Clinics of North America - April 14, 2021 Category: Allergy & Immunology Source Type: research

Contributors
AMAL H. ASSA ’AD, MD (Source: Immunology and Allergy Clinics of North America)
Source: Immunology and Allergy Clinics of North America - April 14, 2021 Category: Allergy & Immunology Source Type: research

Contents
Amal H. Assa ’ad (Source: Immunology and Allergy Clinics of North America)
Source: Immunology and Allergy Clinics of North America - April 14, 2021 Category: Allergy & Immunology Source Type: research

Forthcoming Issues
Skin Allergy (Source: Immunology and Allergy Clinics of North America)
Source: Immunology and Allergy Clinics of North America - April 14, 2021 Category: Allergy & Immunology Source Type: research

The Phenotype of the Food-Allergic Patient
Food allergy ’s increasing prevalence across the globe has initiated research into risk factors associated with the disease and coexistence with other allergic diseases. Longitudinal birth cohorts have identified food allergy phenotypes of patients based on genetic background, racial diversity, and environment al factors. Identifying food sensitization patterns and coexistence of other allergic diseases allows physicians to provide appropriate care for food allergy and personalized anticipatory guidance for the appearance of other allergic diseases. The authors seek to detail key findings of 4 longitudina l allergy birth...
Source: Immunology and Allergy Clinics of North America - March 25, 2021 Category: Allergy & Immunology Authors: Amy A. Eapen, Haejin Kim Source Type: research

Biologics and Novel Therapies for Food Allergy
Food allergy is a significant public health burden affecting around 10% of adults and 8% of children. Although the first peanut oral immunotherapy product received Food and Drug Administration approval in 2020, there is still an unmet need for more effective therapeutic options that minimize the risk of anaphylaxis, nutritional deficiencies, and patient ’s quality of life. Biologics are promising modalities, as they may improve compliance, target multiple food allergies, and treat other concomitant atopic diseases. Although omalizumab has been evaluated extensively, most biologics are more novel and have broader immunolo...
Source: Immunology and Allergy Clinics of North America - March 25, 2021 Category: Allergy & Immunology Authors: Sultan Albuhairi, Rima Rachid Source Type: research

Genetics of Food Allergy
The risk factors for food allergy (FA) include both genetic variants and environmental factors. Advances using both candidate-gene association studies and genome-wide approaches have led to the identification of FA-associated genes involved in immune responses and skin barrier functions. Epigenetic changes have also been associated with the risk of FA. In this chapter, we outline current understanding of the genetics, epigenetics and the interplay with environmental risk factors associated with FA. Future studies of gene-environment interactions, gene-gene interactions, and multi-omics integration may help shed light on th...
Source: Immunology and Allergy Clinics of North America - March 25, 2021 Category: Allergy & Immunology Authors: Elisabet Johansson, Tesfaye B. Mersha Source Type: research

Focus on the Patient with Food Allergy
Much has been written about food allergy in scientific journals and in the lay press. This issue takes a novel and different view in that the focus is on the patient with food allergy. The issue opens with a most comprehensive review by Krempski and colleagues from Dr. Nadeau's group of the bidirectional flow between clinical knowledge and basic research, how mouse studies complement human studies, how both generate novel diagnostics and therapeutics and utilize novel systems biology, making food allergy an excellent example of translation research. (Source: Immunology and Allergy Clinics of North America)
Source: Immunology and Allergy Clinics of North America - March 25, 2021 Category: Allergy & Immunology Authors: Amal H. Assa ’ad Tags: Preface Source Type: research

The Infant Microbiome and Its Impact on Development of Food Allergy
The prevalence of food allergy (FA) has been increasing over the past few decades; recent statistics suggest that FA has an impact on up to 10% of the population and 8% of children. Although the pathogenesis of FA is unclear, studies suggest gut microbiome plays a role in the development of FA. The gut microbiome is influenced by infant feeding method, infant diet, and maternal diet during lactation. Breastfeeding, Mediterranean diet, and probiotics are associated with commensal gut microbiota that protect against FA. This area of research is essential to discovering potential preventive methods or therapeutic targets agai...
Source: Immunology and Allergy Clinics of North America - March 24, 2021 Category: Allergy & Immunology Authors: Kylie N. Jungles, Kassidy M. Jungles, Leah Greenfield, Mahboobeh Mahdavinia Source Type: research

The Unmet Needs of Patients with Food Allergies
This article reviews the unmet needs of patients with food allergies. Anxiety is common among patients with food allergies and their caregivers, which naturally stems from the avoidance, exposure, and uncertainty involved in care. Anxiety associated with allergen avoidance can have both adaptive and detrimental effects on overall health. Anxiety has implications for transitioning the responsibility of health and well-being from caregivers to the patients. As more children with food allergies become adults with food allergies, this will be an urgent topic. Moreover, as more exposure-based therapies become available, underst...
Source: Immunology and Allergy Clinics of North America - March 24, 2021 Category: Allergy & Immunology Authors: Melissa L. Engel, Bryan J. Bunning Source Type: research

Psychosocial Aspects of Food Allergy
This article reviews developmental milestones within the context of food allergy in infancy, school-age children, adolescents, and adults. Recommendations for promoting resilience in patients with food allergy are provided. (Source: Immunology and Allergy Clinics of North America)
Source: Immunology and Allergy Clinics of North America - March 24, 2021 Category: Allergy & Immunology Authors: Christine J. Rubeiz, Michelle M. Ernst Source Type: research

Racial/Ethnic Differences in Food Allergy
Immunoglobulin E –mediated food allergy is an increasingly prevalent public health concern globally. In North America, particularly in the United States, racial and ethnic differences in food allergy prevalence and rates of sensitization have become apparent. Black and Hispanic children in the United States have b een estimated to have the highest rates of food allergy. Beyond rates of prevalence, food allergy outcomes, such as health care utilization, psychosocial outcomes, and economic burden, also vary considerably by race and ethnicity. It is important to consider socioeconomic status in conjunction with race and eth...
Source: Immunology and Allergy Clinics of North America - March 24, 2021 Category: Allergy & Immunology Authors: Christopher M. Warren, Audrey G. Brewer, Benjamin Grobman, Jialing Jiang, Ruchi S. Gupta Source Type: research

Tackling Food Allergy in Infancy
This article focuses on identification, diagnosis, management, and prevention of food allergy in the infant population. (Source: Immunology and Allergy Clinics of North America)
Source: Immunology and Allergy Clinics of North America - March 24, 2021 Category: Allergy & Immunology Authors: Ashley Lynn Devonshire, Adora A. Lin Source Type: research

Developing National and International Guidelines
Food allergy (FA) is considered an emerging public health problem. The development of evidence-based guidelines aims to help health care professionals in an accurate diagnosis and management of such diseases. It is proven that there are differences in the factors that determine FA in the different regions of the world. It is necessary to encourage standardization processes of guidelines development. Nevertheless, in the future it will be necessary to take into consideration not only a methodologically correct analysis of the evidence but also the socio-economic realities where the guidelines will be applied. (Source: Immun...
Source: Immunology and Allergy Clinics of North America - March 24, 2021 Category: Allergy & Immunology Authors: Maurizio Mennini, Stefania Arasi, Alessandro Giovanni Fiocchi, Amal Assa'ad Source Type: research

Effect of Climate Change on Allergenic Airborne Pollen in Japan
In Japan, the representative allergenic airborne pollen-related allergic diseases include Cupressaceae in early spring, the birch family and grass in spring and mugwort in autumn. As a result of a long- term survey the past 27 to 33 years, an increasing in the amount of conifer airborne pollen and an earlier start dispersal were observed, related climate change. In addition, an increase in the number of patients with Japanese cedar pollinosis and the severity has been observed. Provision of medical pollen information, medication and sublingual immunotherapy have all been enhanced. Recently, pollen-food allergic syndrome ha...
Source: Immunology and Allergy Clinics of North America - November 21, 2020 Category: Allergy & Immunology Authors: Reiko Kishikawa, Eiko Koto Source Type: research