T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1
This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb ref...
Source: Immunobiology - September 1, 2023 Category: Allergy & Immunology Authors: Roberto de Sena Rodrigues J únior J éssica Antonia Nunes Gomes George Alberto da Silva Dias Satomi Fujihara Gilberto Toshimitsu Yoshikawa Roberta Vilela Lopes Koyama Rita Catarina Medeiros Sousa Juarez Antonio Sim ões Quaresma Hellen Thais Fuzii Source Type: research
T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1
This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb ref...
Source: Immunobiology - September 1, 2023 Category: Allergy & Immunology Authors: Roberto de Sena Rodrigues J únior J éssica Antonia Nunes Gomes George Alberto da Silva Dias Satomi Fujihara Gilberto Toshimitsu Yoshikawa Roberta Vilela Lopes Koyama Rita Catarina Medeiros Sousa Juarez Antonio Sim ões Quaresma Hellen Thais Fuzii Source Type: research
T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1
This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb ref...
Source: Immunobiology - September 1, 2023 Category: Allergy & Immunology Authors: Roberto de Sena Rodrigues J únior J éssica Antonia Nunes Gomes George Alberto da Silva Dias Satomi Fujihara Gilberto Toshimitsu Yoshikawa Roberta Vilela Lopes Koyama Rita Catarina Medeiros Sousa Juarez Antonio Sim ões Quaresma Hellen Thais Fuzii Source Type: research
T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1
This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb ref...
Source: Immunobiology - September 1, 2023 Category: Allergy & Immunology Authors: Roberto de Sena Rodrigues J únior J éssica Antonia Nunes Gomes George Alberto da Silva Dias Satomi Fujihara Gilberto Toshimitsu Yoshikawa Roberta Vilela Lopes Koyama Rita Catarina Medeiros Sousa Juarez Antonio Sim ões Quaresma Hellen Thais Fuzii Source Type: research
T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1
This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb ref...
Source: Immunobiology - September 1, 2023 Category: Allergy & Immunology Authors: Roberto de Sena Rodrigues J únior J éssica Antonia Nunes Gomes George Alberto da Silva Dias Satomi Fujihara Gilberto Toshimitsu Yoshikawa Roberta Vilela Lopes Koyama Rita Catarina Medeiros Sousa Juarez Antonio Sim ões Quaresma Hellen Thais Fuzii Source Type: research
T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1
This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb ref...
Source: Immunobiology - September 1, 2023 Category: Allergy & Immunology Authors: Roberto de Sena Rodrigues J únior J éssica Antonia Nunes Gomes George Alberto da Silva Dias Satomi Fujihara Gilberto Toshimitsu Yoshikawa Roberta Vilela Lopes Koyama Rita Catarina Medeiros Sousa Juarez Antonio Sim ões Quaresma Hellen Thais Fuzii Source Type: research
T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1
This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb ref...
Source: Immunobiology - September 1, 2023 Category: Allergy & Immunology Authors: Roberto de Sena Rodrigues J únior J éssica Antonia Nunes Gomes George Alberto da Silva Dias Satomi Fujihara Gilberto Toshimitsu Yoshikawa Roberta Vilela Lopes Koyama Rita Catarina Medeiros Sousa Juarez Antonio Sim ões Quaresma Hellen Thais Fuzii Source Type: research
T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1
This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb ref...
Source: Immunobiology - September 1, 2023 Category: Allergy & Immunology Authors: Roberto de Sena Rodrigues J únior J éssica Antonia Nunes Gomes George Alberto da Silva Dias Satomi Fujihara Gilberto Toshimitsu Yoshikawa Roberta Vilela Lopes Koyama Rita Catarina Medeiros Sousa Juarez Antonio Sim ões Quaresma Hellen Thais Fuzii Source Type: research
Complement and coagulation crosstalk - Factor H in the spotlight
Immunobiology. 2023 Jul 12;228(6):152707. doi: 10.1016/j.imbio.2023.152707. Online ahead of print.ABSTRACTThe immune complement and the coagulation systems are blood-based proteolytic cascades that are activated by pathway-specific triggers, based on protein-protein interactions and enzymatic cleavage reactions. Activation of these systems is finely balanced and controlled through specific regulatory mechanisms. The complement and coagulation systems are generally viewed as distinct, but have common evolutionary origins, and several interactions between these homologous systems have been reported. This complement and coagu...
Source: Immunobiology - August 26, 2023 Category: Allergy & Immunology Authors: Meike Heurich Genevi ève McCluskey Source Type: research
Complement and coagulation crosstalk - Factor H in the spotlight
Immunobiology. 2023 Jul 12;228(6):152707. doi: 10.1016/j.imbio.2023.152707. Online ahead of print.ABSTRACTThe immune complement and the coagulation systems are blood-based proteolytic cascades that are activated by pathway-specific triggers, based on protein-protein interactions and enzymatic cleavage reactions. Activation of these systems is finely balanced and controlled through specific regulatory mechanisms. The complement and coagulation systems are generally viewed as distinct, but have common evolutionary origins, and several interactions between these homologous systems have been reported. This complement and coagu...
Source: Immunobiology - August 26, 2023 Category: Allergy & Immunology Authors: Meike Heurich Genevi ève McCluskey Source Type: research
Complement and coagulation crosstalk - Factor H in the spotlight
Immunobiology. 2023 Jul 12;228(6):152707. doi: 10.1016/j.imbio.2023.152707. Online ahead of print.ABSTRACTThe immune complement and the coagulation systems are blood-based proteolytic cascades that are activated by pathway-specific triggers, based on protein-protein interactions and enzymatic cleavage reactions. Activation of these systems is finely balanced and controlled through specific regulatory mechanisms. The complement and coagulation systems are generally viewed as distinct, but have common evolutionary origins, and several interactions between these homologous systems have been reported. This complement and coagu...
Source: Immunobiology - August 26, 2023 Category: Allergy & Immunology Authors: Meike Heurich Genevi ève McCluskey Source Type: research
Complement and coagulation crosstalk - Factor H in the spotlight
Immunobiology. 2023 Jul 12;228(6):152707. doi: 10.1016/j.imbio.2023.152707. Online ahead of print.ABSTRACTThe immune complement and the coagulation systems are blood-based proteolytic cascades that are activated by pathway-specific triggers, based on protein-protein interactions and enzymatic cleavage reactions. Activation of these systems is finely balanced and controlled through specific regulatory mechanisms. The complement and coagulation systems are generally viewed as distinct, but have common evolutionary origins, and several interactions between these homologous systems have been reported. This complement and coagu...
Source: Immunobiology - August 26, 2023 Category: Allergy & Immunology Authors: Meike Heurich Genevi ève McCluskey Source Type: research
Complement and coagulation crosstalk - Factor H in the spotlight
Immunobiology. 2023 Jul 12;228(6):152707. doi: 10.1016/j.imbio.2023.152707. Online ahead of print.ABSTRACTThe immune complement and the coagulation systems are blood-based proteolytic cascades that are activated by pathway-specific triggers, based on protein-protein interactions and enzymatic cleavage reactions. Activation of these systems is finely balanced and controlled through specific regulatory mechanisms. The complement and coagulation systems are generally viewed as distinct, but have common evolutionary origins, and several interactions between these homologous systems have been reported. This complement and coagu...
Source: Immunobiology - August 26, 2023 Category: Allergy & Immunology Authors: Meike Heurich Genevi ève McCluskey Source Type: research
Lycopene alleviates food allergy by modulating the PI3K/AKT pathway in peanut-sensitized BALB/c mice
Immunobiology. 2023 Aug 15;228(6):152731. doi: 10.1016/j.imbio.2023.152731. Online ahead of print.ABSTRACTFood allergies, which lead to life-threatening acute symptoms, are considered an important public health problem. Therefore, it is essential to develop efficient preventive and treatment measures. We developed a crude peanut protein extract (PPE)-induced allergy mouse model to investigate the effects of lycopene on peanut allergy. Mice were divided into four groups: 5 mg/kg lycopene, 20 mg/kg lycopene, no treatment, and control groups. Serum inflammatory factors were detected using enzyme-linked immunosorbent assay. In...
Source: Immunobiology - August 22, 2023 Category: Allergy & Immunology Authors: Hongjuan He Xiaoyan Ji Lihua Cao Zhenzhen Wang Xiaoyu Wang Xiu-Min Li Mingsan Miao Source Type: research
XXIX International Complement Workshop Newcastle 2023
Immunobiology. 2023 Sep;228(5):152729. doi: 10.1016/j.imbio.2023.152729. Epub 2023 Aug 10.NO ABSTRACTPMID:37607846 | DOI:10.1016/j.imbio.2023.152729 (Source: Immunobiology)
Source: Immunobiology - August 22, 2023 Category: Allergy & Immunology Authors: Kevin J Marchbank David Kavanagh Claire L Harris Source Type: research
