Location, Location, Location: The Role of Objective Neighborhood Characteristics for Perceptions of Control
Conclusion: Findings highlight the importance of access to neighborhood resources for control beliefs across old age and can inform interventions to build up neighborhood characteristics which might be especially helpful in residential areas with high unemployment.Gerontology (Source: Gerontology)
Source: Gerontology - May 17, 2021 Category: Geriatrics Source Type: research

Social Support and Functional Decline in the Oldest Old
Discussion: Our findings highlight the meaning of social support for functional status among the oldest old. Finding ways to sustain social support in highest age may be a promising approach in order to postpone functional decline.Gerontology (Source: Gerontology)
Source: Gerontology - May 12, 2021 Category: Geriatrics Source Type: research

Reinforcement Effects of Social Network Intervention during Nutritional Supplementation in Frail Older Adults
Conclusion: Our results indicate that social network intervention combined with protein supplementation can improve both the magnitude and duration of functional status among frail older community-dwelling adults.Gerontology (Source: Gerontology)
Source: Gerontology - May 11, 2021 Category: Geriatrics Source Type: research

Prevalence of Polypharmacy and Risks of Potentially Inappropriate Medication Use in the Older Population in a Developing Country: A Systematic Review and Meta-Analysis
Conclusion: This first meta-analysis from a developing country revealed a high prevalence of polypharmacy and PIM use in the Ethiopian older population. There was no awareness about the risk of PIMs in patients with polypharmacy and polymorbidity, and older age significantly predicted PIM use. Interventions ensuring rational geriatric pharmacotherapy are essential in developing countries in order to reduce the expected burden of PIM-related geriatric morbidity, higher costs, and mortality.Gerontology (Source: Gerontology)
Source: Gerontology - May 11, 2021 Category: Geriatrics Source Type: research

Digital Biomarkers of Cognitive Frailty: The Value of Detailed Gait Assessment Beyond Gait Speed
Conclusions: This study suggests that gait performances measured by wearable sensors are potential digital biomarkers of CF among older adults. Dual-task gait and other detailed gait metrics provide value for identifying CF above gait speed alone. Future studies need to examine the potential benefits of gait performances for early diagnosis of CF and/or tracking its severity over time.Gerontology (Source: Gerontology)
Source: Gerontology - May 10, 2021 Category: Geriatrics Source Type: research

Effects of Short- and Long-Term Aerobic-Strength Training and Determinants of Walking Speed in the Elderly
Conclusions: Supervised aerobic-strength training increased WS, strength, and dynamics of voluntary knee extension as well as habitual physical activity in older individuals. Favorable changes in WS were sustainable over the 21-month period by a lower dose of aerobic-strength training. Training effects on WS were not limited by age, and cerebellar cortex volume was the key determinant of WS.Gerontology (Source: Gerontology)
Source: Gerontology - May 10, 2021 Category: Geriatrics Source Type: research

Apolipoprotein E4 Allele in Subjects with COVID-19
Gerontology (Source: Gerontology)
Source: Gerontology - May 7, 2021 Category: Geriatrics Source Type: research

Plasma Amino Acids and Risk of Impaired Lower-Extremity Function and Role of Dietary Intake: A Nested Case-Control Study in Older Adults
Conclusion: Some amino acid species could serve as risk markers for physical function decline in older adults, and healthy diet might attenuate the excess risk of ILEF linked to essential amino acids.Gerontology (Source: Gerontology)
Source: Gerontology - May 7, 2021 Category: Geriatrics Source Type: research

Racial/Ethnic Differences in the Longitudinal Effects of Fear of Falling on Falls
Conclusions: Clear evidence of racial/ethnic differences was found in the relationship between fear of falling and falls among community-dwelling older adults in the USA. Special attention should be paid to black older adults with a fear of falling but have not fallen down recently and Hispanics with fear of falling and have fallen in the past year. Readily available educational programs should be actively advertised to older adults to reduce the fear of falling, and at the same time, culturally tailored educational programs should be developed for older adults from racial/ethnic minority backgrounds.Gerontology (Source: Gerontology)
Source: Gerontology - May 6, 2021 Category: Geriatrics Source Type: research

Quick Sequential Organ Failure Assessment, Sequential Organ Failure Assessment, and Procalcitonin for Early Diagnosis and Prediction of Death in Elderly Patients with Suspicion of Sepsis in the Emergency Department, Based on Sepsis-3 Definition
Conclusion: In the elderly population with suspicion of infection on admission to the emergency department, qSOFA presents a low diagnostic performance of confirmed sepsis and in-hospital mortality, for which other tools with higher diagnostic and prognostic performance should be added, such as PCT and lactate.Gerontology (Source: Gerontology)
Source: Gerontology - May 5, 2021 Category: Geriatrics Source Type: research

Life Satisfaction during the Transition to Widowhood among Japanese Older Adults
Discussion: Our results show that spousal bereavement has, on average, an initial negative impact on well-being with substantial individual differences in recovery 1 year later. When designing interventions to promote adaptation after spousal loss, it is important to consider the bereaved individual ’s cultural background and preloss resources.Gerontology (Source: Gerontology)
Source: Gerontology - May 4, 2021 Category: Geriatrics Source Type: research

Slower Decline in Processing Speed Is Associated with Familial Longevity
Conclusion: Individuals in families with longevity appear to have better cognitive performance than their spouses for cognitive processes including psychomotor processing, episodic memory, and retrieval. Additionally, they demonstrate longer cognitive health spans with a slower decline on a multifactorial test of processing speed, a task requiring the integration of processes including organized visual search, working and incidental memory, and graphomotor ability. Long-lived families may be a valuable cohort for studying resilience to cognitive aging.Gerontology (Source: Gerontology)
Source: Gerontology - May 4, 2021 Category: Geriatrics Source Type: research

Evaluation of Motor and Cognitive Performance in People with Parkinson ’s Disease Using Instrumented Trail-Making Test
Conclusion: This study demonstrated the feasibility and early results supporting the potential application of iTMT to determine cognitive-motor and distinguishing individuals with MCI and PD from CN-older adults. Future studies are warranted to test the ability of iTMT to track its subtle changes over time.Gerontology (Source: Gerontology)
Source: Gerontology - May 3, 2021 Category: Geriatrics Source Type: research

Microphthalmia-Associated Transcription Factor in Senescence and Age-Related Diseases
Although microphthalmia-associated transcription factor (MITF) has been known for decades as a key regulator for melanocytic differentiation, recent studies expanded its other roles in multiple biological processes. Among these newfound roles, the relationship between MITF and aging is attractive; however, the underlying mechanism remains elusive. Here, we review the documented cues that highlight the implication of MITF in the aging process and particularly discuss the possible mechanisms underlying the participation of MITF in cellular senescence. First, it summarizes the association of MITF with melanocytic senescence, ...
Source: Gerontology - May 3, 2021 Category: Geriatrics Source Type: research

Crucial Role of Respite Care in Supporting Informal Caregivers: A Challenge for the Care of Older Adults in the Middle East and North Africa
In conclusion, those receiving care, caregivers, and the public health-care s ystem will gain from the development of a range of respite care services.Gerontology (Source: Gerontology)
Source: Gerontology - April 29, 2021 Category: Geriatrics Source Type: research