Is There Any Link between Cognitive Impairment and Gut Microbiota? A Systematic Review
Conclusions: The gut microbiota may alter brain function or trigger various psychiatric conditions through the gut-brain axis. Prospective studies are needed in order to explore the role of the gut microbiota in the etiology of dementia and to achieve clinical recommendations.Gerontology (Source: Gerontology)
Source: Gerontology - March 9, 2022 Category: Geriatrics Source Type: research
Direct and Indirect Effects of COVID-19 on Long-Term Care Residents and Their Family Members
Conclusion: The interplay of multiple factors affected LTCF residents against the backdrop of COVID-19 restrictions. The emergence of mitigating factors which provide solutions to some of the challenges has the potential of improving quality of care for LTCF residents as the pandemic continues and thereafter.Gerontology (Source: Gerontology)
Source: Gerontology - March 8, 2022 Category: Geriatrics Source Type: research
Relevance of Cardiovascular Risk Factors Screening in People Aged over 65 Years: Results from a Large French Urban Population (The CARVAR92 Study)
Conclusions: Screening CVRFs especially hypertension remains relevant in people aged over 65 years as it enables to detect unknown CVRFs in numerous subjects. Increasing awareness of CVRFs may be the first step to CVRF control, which is known to be efficient on cardiovascular mortality and functional autonomy in later life.Gerontology (Source: Gerontology)
Source: Gerontology - March 2, 2022 Category: Geriatrics Source Type: research
The Association of Weight Loss, Weight Status, and Abdominal Obesity with All-Cause Mortality in Older Adults
Conclusion: In community-dwelling adults aged ≥65 years, abdominal obesity was strongly associated with increased mortality risk. Being overweight appeared, however, to be protective against mortality. Modest self-reported weight loss was not associated with all-cause mortality in community-dwelling older adults after adjusting for health and lifestyle factors. However, men reporting recent weight loss of more than 3 kg may be at increased risk. The findings of this study support the use of WC, rather than BMI, as a predictor of mortality risk in older adults.Gerontology (Source: Gerontology)
Source: Gerontology - February 17, 2022 Category: Geriatrics Source Type: research
Older Persons Displaying Parkinsonian Gait: Prediction and Explanation of the Recurrent Falling Phenomenon and Its Related Poor Prognosis
Conclusion: Within this population of older persons presenting parkinsonian gait, a previous history of falls and abnormal posture may be used to easily identify individuals at risk of recurrent falls. Cognitive decline and fluctuations may underlie the transition of NRF to RF.Gerontology (Source: Gerontology)
Source: Gerontology - February 11, 2022 Category: Geriatrics Source Type: research
BNT162b2 mRNA COVID-19 (Comirnaty) Vaccine Effectiveness in Elderly Patients Who Live in Long-Term Care Facilities: A Nationwide Cohort
Conclusion: This study shows that the BNT162b2 mRNA COVID-19 vaccine effectively prevents SARS-CoV-2 infection, COVID-19-related death, and all-cause mortality in LTCF residents. Further research is warranted on the effect of the third vaccine (booster) in this population.Gerontology (Source: Gerontology)
Source: Gerontology - February 8, 2022 Category: Geriatrics Source Type: research
Erratum
Gerontology (Source: Gerontology)
Source: Gerontology - February 7, 2022 Category: Geriatrics Source Type: research
Long-Term Effects on Preventing Frailty and Health Care Costs Associated with a Multifactorial Intervention in the Elderly: Three-Year Follow-Up Data from the Pre-Frail 80 Study
Conclusions: A multifactorial, interdisciplinary intervention carried out in primary care prevented frailty in pre-frail elderly people at 36-month follow-up. Although the IG was grouped into higher grade Clinical Risk Groups and therefore had greater morbidity, the cost was lower than that in the CG.Gerontology (Source: Gerontology)
Source: Gerontology - February 4, 2022 Category: Geriatrics Source Type: research
Sense of Purpose in Life and Markers of Hearing Function: Replicated Associations across Two Longitudinal Cohorts
Discussion: Across samples, measures, and analytical approaches, the present research indicates replicable associations between sense of purpose in life and hearing health. It further indicates that hearing may be one factor that associates purpose with better episodic memory.Gerontology (Source: Gerontology)
Source: Gerontology - February 3, 2022 Category: Geriatrics Source Type: research
Frail Older Adults with Presymptomatic SARS-CoV-2 Infection: Clinical Course and Prognosis
Conclusions: In this large cohort, we report care and prognosis of asymptomatic older adults with major functional or cognitive impairments during the COVID-19 pandemic. Most presymptomatic patients do not develop severe infection, and age stays a predominant risk factor, even in the frailest older adults.Gerontology (Source: Gerontology)
Source: Gerontology - January 31, 2022 Category: Geriatrics Source Type: research
Age-Related Changes in the Composition of Intestinal Microbiota in Elderly Chinese Individuals
Conclusions: The diversity of intestinal microbiota in the oldest participants (centenarians) decreased significantly, with several beneficial bacterial strains showing increased or decreased abundance; harmful bacterial species showed a similar trend. Our oldest participants (centenarians) demonstrated significantly increased levels of pro-inflammatory cytokines, which may be related to inflammaging.Gerontology (Source: Gerontology)
Source: Gerontology - January 31, 2022 Category: Geriatrics Source Type: research
Risk Assessment of Mortality in Elderly Individuals: A Nationwide Cohort Study
Conclusions: Our results showed the relationship between each condition and mortality rate among elderly individuals in Korea. Our nomogram showed a satisfactory performance in the assessment of the risk of all-cause mortality in elderly Korean people.Gerontology (Source: Gerontology)
Source: Gerontology - January 31, 2022 Category: Geriatrics Source Type: research
Muscle Mass and Inflammation in Older Adults: Impact of the Metabolic Syndrome
Conclusions: Among BASE-II participants, low ALMBMI was associated with inflammation. Low-grade inflammation triggered by disease state, especially in the context of MetS, might favor loss of muscle mass, so a better control of MetS might help to prevent sarcopenia. Intervention studies to test whether strategies to prevent MetS might also prevent loss of muscle mass seem to be promising.Gerontology (Source: Gerontology)
Source: Gerontology - January 31, 2022 Category: Geriatrics Source Type: research
Instrumented Functional Test for Objective Outcome Evaluation of Balance Rehabilitation in Elderly Fallers: A Clinical Study
Conclusion: IMUs enable not only the characterization of underlying causes of impaired balance but also the identification of improved and yet impaired aspects of balance post-rehabilitation. Hence, IMUs allow us to characterize risk factors post-rehabilitation in elderly fallers, whereas the BBS scores only show changes in overall balance. It is crucial to objectively evaluate the effectiveness of such interventions to reduce future falls and their adverse consequences. Therefore, instrumented balance assessment is recommended since it can provide quantitative and objective measures for clinical outcome evaluations.Geront...
Source: Gerontology - January 28, 2022 Category: Geriatrics Source Type: research
Sestrins ’ Expression in the Liver Is Not Altered by Short-Term Calorie Restriction in Young and Old Rats
Conclusion: Sestrins ’ hepatic expression is only minimally affected by SCR in young and old rats. We propose that sestrins may not be a major effector of mild SCR in the liver of young or old rats.Gerontology (Source: Gerontology)
Source: Gerontology - January 27, 2022 Category: Geriatrics Source Type: research
