Longitudinal Follow-Up Studies on the Bidirectional Association between ADL/IADL Disability and Multimorbidity: Results from Two National Sample Cohorts of Middle-Aged and Elderly Adults
Conclusion: The consistent findings across 2 national longitudinal studies supported a strong bidirectional association between disability and multimorbidity among middle-aged and elderly adults. Thus, tailored interventions should be taken to prevent the mutual development of disability and multimorbidity.Gerontology (Source: Gerontology)
Source: Gerontology - June 28, 2021 Category: Geriatrics Source Type: research
Management of Older Outpatients during the COVID-19 Pandemic: The GeroCovid Ambulatory Study
Conclusion: Our study suggests that contacts through telephone and video consultations are likely associated with a health status preservation of the patients.Gerontology (Source: Gerontology)
Source: Gerontology - June 28, 2021 Category: Geriatrics Source Type: research
Aging and Mesenchymal Stem Cells: Therapeutic Opportunities and Challenges in the Older Group
With aging, a portion of cells, including mesenchymal stem cells (MSCs), become senescent, and these senescent cells accumulate and promote various age-related diseases. Therefore, the older age group has become a major population for MSC therapy, which is aimed at improving tissue regeneration and function of the aged body. However, the application of MSC therapy is often unsatisfying in the aged group. One reasonable conjecture for this correlation is that aging microenvironment reduces the number and function of MSCs. Cellular senescence also plays an important role in MSC function impairment. Thus, it is necessary to e...
Source: Gerontology - June 23, 2021 Category: Geriatrics Source Type: research
Effects of a Video-Based mHealth Program for Homebound Older Adults: Study Protocol for a Pilot Randomized Controlled Trial
This study attempts to bring this group of older adults to providers ’ attention by designing a health-social-oriented self-care mobile Health (mHealth) program and subjecting it to empirical testing. The aim of this study is to shift the current reactive, cure-oriented approach to a preventive and health-promoting model, empowering homebound older adults to take a n active role in their health, be responsive to their care needs, and subsequently improve their holistic health.Methods: This is a pilot randomized controlled trial. The study is supported by 5 community centers with an estimated sample size of 68 subjects. T...
Source: Gerontology - June 23, 2021 Category: Geriatrics Source Type: research
A High Masticatory Muscle Tone Predicts the Risk of Malnutrition and Frailty in Inpatient Older Adults: A Cross-Sectional Study
Conclusions: A high masticatory muscle tone predicts malnutrition and frailty. Medical professionals should combat masticatory dysfunction-induced malnutrition by detecting masticatory muscle performance using sEMG and referring patients to dental professionals. Additionally, encouraging inpatient older adults to perform oral motor exercise is recommended.Gerontology (Source: Gerontology)
Source: Gerontology - June 17, 2021 Category: Geriatrics Source Type: research
Social Disconnection and Living Arrangements among Older Adults: The Singapore Chinese Health Study
Conclusion: Though living alone is associated with social disconnection, most socially disconnected individuals lived with family. Community interventions could focus on those in poor health despite living with family and older men living alone.Gerontology (Source: Gerontology)
Source: Gerontology - June 16, 2021 Category: Geriatrics Source Type: research
Statin Intake and All-Cause Mortality among Older Nursing Home Residents
Conclusions: The statin intake was associated with decreased all-cause mortality in older people residing in nursing homes. More in-depth studies investigating the potential geroprotector effect of statins in this population are needed.Gerontology (Source: Gerontology)
Source: Gerontology - June 16, 2021 Category: Geriatrics Source Type: research
Indoleamine-2,3-Dioxygenase Activates Wnt/ β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury
Conclusions: IRI could increase IDO expression to activate Wnt/ β-catenin pathway resulting kidney fibrosis. PGE2 could ameliorate kidney fibrosis via inhibiting IDO expression.Gerontology (Source: Gerontology)
Source: Gerontology - June 15, 2021 Category: Geriatrics Source Type: research
Factors and Outcomes of Intensive Care Unit Readmission in Elderly Patients
Conclusions: ICU readmissions occurred in 9.2% of elderly patients and were associated with poor prognosis and higher mortality.Gerontology (Source: Gerontology)
Source: Gerontology - June 9, 2021 Category: Geriatrics Source Type: research
Structural and Functional Aspects of Social Relationships and Episodic Memory: Between-Person and Within-Person Associations in Middle-Aged and Older Adults
Discussion: Both structural and functional aspects of social relationships contribute to between-person differences in levels and fluctuations of episodic memory performance. Ups and downs of relationships to relatives, social contact, and feelings of loneliness contribute to ups and downs of episodic memory. Potential mechanisms underlying these associations are discussed.Gerontology (Source: Gerontology)
Source: Gerontology - June 8, 2021 Category: Geriatrics Source Type: research
International Practice Recommendations for the Recognition and Management of Hearing and Vision Impairment in People with Dementia
Conclusion: This is the first set of international, interdisciplinary practice recommendations that will guide the development of multidisciplinary services and policy to improve the lives of people with dementia and hearing and vision impairment.Gerontology (Source: Gerontology)
Source: Gerontology - June 4, 2021 Category: Geriatrics Source Type: research
Association with Longevity of Phosphatidylinositol 3-Kinase Regulatory Subunit 1 Gene Variants Stems from Protection against Mortality Risk in Men with Cardiovascular Disease
Conclusion: Our study provides novel insights into the basis forPIK3R1 as a longevity gene. We suggest that thePIK3R1 longevity genotype attenuates mortality risk in at-risk individuals by protection against cellular stress caused by CVD.Gerontology (Source: Gerontology)
Source: Gerontology - June 2, 2021 Category: Geriatrics Source Type: research
SARC-F Is Inaccurate to Identify Geriatric Rehabilitation Inpatients at Risk for Sarcopenia: RESORT
Conclusion: The SARC-F showed poor diagnostic accuracy in identifying sarcopenia in geriatric rehabilitation inpatients. Assessment of sarcopenia is recommended without screening.Gerontology (Source: Gerontology)
Source: Gerontology - June 1, 2021 Category: Geriatrics Source Type: research
Age Differences in State Curiosity: Examining the Role of Personal Relevance
Conclusion: Findings replicated previous findings that trait curiosity declined with age, but they also illustrated the distinctions between trait and state curiosity in the context of aging and highlighted the potential role of personal relevance in enhancing curiosity of OAs.Gerontology (Source: Gerontology)
Source: Gerontology - June 1, 2021 Category: Geriatrics Source Type: research
The Modified Healthy Ageing Index Is Associated with Mortality and Disability: The Rugao Longevity and Ageing Study
Conclusion: The modified HAI was a robust and independent predictor of adverse outcomes. It is a valid and feasible tool for monitoring ageing in older adults.Gerontology (Source: Gerontology)
Source: Gerontology - May 17, 2021 Category: Geriatrics Source Type: research
