How to better distinguish between Type II and III selective fetal growth restriction in monochorionic twin pregnancies?
CONCLUSIONS:
The presence of an AA anastomosis, signs of cardiac strain in the large twin, and proximate cord insertions suggested Type III sFGR, whereas placental dichotomy and a severe growth restriction were typically present in Type II. Prospective studies need to validate if these markers help prenatal differentiation between Type II and III sFGR. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - March 1, 2022 Category: Perinatology & Neonatology Source Type: research
Contents
Fetal Diagn Ther 2021;48:I –VIII (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - February 28, 2022 Category: Perinatology & Neonatology Source Type: research
Acknlowledgement to Reviewers
Fetal Diagn Ther 2021;48:863 –864 (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - February 28, 2022 Category: Perinatology & Neonatology Source Type: research
Universal Cell Free DNA or Contingent Screening for Trisomy 21: Does It Make a Difference? A Comparative Study with Real Data
Conclusion: This study demonstrates that a contingent approach provides similar detection rates for trisomy 21 as universal cfDNA screening, by a reduction of 73% the number of cfDNA tests.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - February 22, 2022 Category: Perinatology & Neonatology Source Type: research
Universal cell free DNA or contingent screening for trisomy 21 – does it make a difference?
A comparative study with real data.
Objective:
To compare the detection rate for trisomy 21 of universal cell free DNA (cfDNA) screening with contingent screening.
Methods:
Retrospective study at 3 German centers. The study included euploid and trisomy 21 pregnancies where cfDNA and first trimester (FT) screening assessment was carried out.
The FT risk for trisomy 21 was computed based on combined screening and stratified into the following classes: high risk>1:10, intermediate risk 1:11 – 2,500, low risk (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - February 22, 2022 Category: Perinatology & Neonatology Source Type: research
Clinical correlates of placental pathologic features in early-onset fetal growth restriction.
Introdcution: The purpose of this study was to evaluate the association between placental pathologic features of maternal (MVM) or fetal (FVM) vascular malperfusion and clinical characteristics, sonographic findings and neonatal outcome in a cohort of pregnancies complicated by early-onset (diagnosed before 32 weeks of gestational age) fetal growth restriction (FGR).
Methods: A prospective cohort study included 250 singleton early-onset FGR pregnancies diagnosed, followed up and delivered at a single Centre. Elementary placental pathologic lesions were classified according to standard recommendations. Logistic regression ...
Source: Fetal Diagnosis and Therapy - February 14, 2022 Category: Perinatology & Neonatology Source Type: research
The value of exome sequencing in thoracoamniotic shunt for severe pleural effusion with fetal hydrops: a retrospective clinical study
Conclusions Single gene disorders was one of the major causes of perinatal death in NIHF cases that underwent fetal therapy. Prenatal rapid exome sequencing may be of good promise in NIHF to exploring precise etiology and guide fetal therapy. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - February 9, 2022 Category: Perinatology & Neonatology Source Type: research
Erratum
Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - February 7, 2022 Category: Perinatology & Neonatology Source Type: research
Altered Doppler velocimetry of fetal middle cerebral artery in singleton pregnancies complicated by mild well-controlled gestational diabetes.
Introduction
The aim the present study is to evaluate fetal umbilical artery (UA) and middle cerebral artery (MCA) blood flow in patients with gestational diabetes (GD), in order to determine whether minimal anomalies of glucose metabolism may influence fetal placental function.
Methods
UA and MCA flow were prospectively measured by transabdominal ultrasound in singleton pregnancies between 34 and 37 weeks of gestation.
Results
The study included 35 women with GD and 217 non-diabetic patients. Middle cerebral pusatility index (PI) was significantly higher in the GD group (mean MCA – PI =1.82±0.27 vs 1.71 ±0.26; p...
Source: Fetal Diagnosis and Therapy - February 1, 2022 Category: Perinatology & Neonatology Source Type: research
< b > < i > Fetal Diagnosis and Therapy < /i > < /b > : Farewell as Editor-in-Chief
Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - January 21, 2022 Category: Perinatology & Neonatology Source Type: research
Publisher ’s Note
Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - January 20, 2022 Category: Perinatology & Neonatology Source Type: research
Subamniotic Hemorrhage, a Possible New Presentation of Fetal and Neonatal Alloimmune Thrombocytopenia
Conclusion: A subamniotic hematoma appears to be the first manifestation of FNAIT. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - January 12, 2022 Category: Perinatology & Neonatology Source Type: research
Subamniotic haemorrhage, a possible new presentation of fetal and neonatal alloimmune thrombocytopenia
Conclusion: A subamniotic hematoma appears to be the first manifestation of FNAIT. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - January 12, 2022 Category: Perinatology & Neonatology Source Type: research
Effectiveness of Ultrasound Screening for a Placenta Accreta Spectrum Using Standard Ultrasound Criteria in a Secondary Care Setting
Conclusions: Standardized ultrasound screening protocol in women at risk due to PP in the third trimester was highly effective in detecting PAS in a secondary-level hospital setting. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - January 11, 2022 Category: Perinatology & Neonatology Source Type: research
