Long-Term Outcome of Monochorionic Twins after Fetoscopic Laser Therapy Compared to Matched Dichorionic Twins
Conclusion: The outcome of monochorionic twins treated with FLS is comparable to the outcome of dichorionic twins. Long-term neurodevelopment in the cohort was mainly dependent on GA at birth.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - September 2, 2020 Category: Perinatology & Neonatology Source Type: research
The IFMSS Tower Lecture: Fetal Surgery Past, Fetal Surgery Present, and Fetal Surgery Yet to Come!
Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - September 2, 2020 Category: Perinatology & Neonatology Source Type: research
Reconsidering ECMO in Premature Neonates
Extracorporeal membrane oxygenation (ECMO) is a life-saving intervention for neonates with respiratory failure or congenital cardiac disease refractory to maximal medical management. Early studies showed high rates of mortality and morbidities among preterm and low birthweight (BW) neonates, leading to widely accepted ECMO inclusion criteria of gestational age (GA) ≥34 weeks and BW #x3e;2 kg. In recent years, publications involving neonates of 32–34 weeks GA have reported improved survival and decreased intracranial hemorrhage. As such, ECMO should be considered on a case-by-case basis in premature neonates as long as ...
Source: Fetal Diagnosis and Therapy - September 1, 2020 Category: Perinatology & Neonatology Source Type: research
The Management of Myelomeningocele Study: Short-Term Neonatal Outcomes
Conclusion: The benefits of prenatal surgery outweigh the complications of prematurity.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - August 31, 2020 Category: Perinatology & Neonatology Source Type: research
Developing an Infrastructure for Bereavement Outreach in a Maternal-Fetal Care Center
Although bereavement programs are a common element of palliative medicine and hospice programs, few maternal-fetal care centers offer universal bereavement outreach services following perinatal loss. In this article, we describe the implementation of a bereavement outreach program at the Center for Fetal Diagnosis and Treatment at the Children ’s Hospital of Philadelphia. The four primary goals identified when developing the bereavement outreach protocol included: (1) centralize communication for patient tracking when a perinatal loss occurs, (2) provide individualized and consistent resource support for grieving patient...
Source: Fetal Diagnosis and Therapy - August 31, 2020 Category: Perinatology & Neonatology Source Type: research
Early Prophylactic Enoxaparin for the Prevention of Preeclampsia and Intrauterine Growth Restriction: A Randomized Trial
Conclusion: LMWH did not reduce the incidence of placenta-mediated complications either in women with previous adverse obstetric history without thrombophilia or in women selected by first trimester screening for PE. Based on these results, we cannot recommend the use of LMWH alone in women at risk of placental complications.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - August 25, 2020 Category: Perinatology & Neonatology Source Type: research
Inter- and Intraobserver Agreement in First Trimester Ultrasound Evaluation of Placental Biometry
Conclusions: PV, PT, and CP are reproducible measurements to evaluate first trimester placental biometry. Further research is needed to assess the clinical utility of these variables as predictors of poor obstetric outcomes.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - August 12, 2020 Category: Perinatology & Neonatology Source Type: research
Response to “Contemporary Outcomes of Patients with Isolated Bilateral Renal Agenesis with and without Fetal Intervention” by RAFT Investigators
Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - August 7, 2020 Category: Perinatology & Neonatology Source Type: research
Risk Factors for Co-Twin Fetal Demise following Radiofrequency Ablation in Multifetal Monochorionic Gestations
Conclusion: Co-twin FGR was associated with an increased risk of post-RFA demise. When compared to other indications, patients with TRAP sequence were less likely to have a co-twin demise.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - August 7, 2020 Category: Perinatology & Neonatology Source Type: research
Twin-Twin Transfusion Syndrome Complicated by Proximate Placental Cord Insertion Sites: Endoscopic Clip-Assisted Laser Occlusion
Conclusion: Endoscopic clip-assisted laser occlusion of a placental vessel is technically feasible and may be a useful therapeutic option in select cases.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - August 6, 2020 Category: Perinatology & Neonatology Source Type: research
Survival Outcomes by Fetal Weight Discordance after Laser Surgery for Twin-Twin Transfusion Syndrome Complicated by Donor Fetal Growth Restriction
Discussion: In TTTS cases complicated by donor IUGR with severe growth discordance, laser surgery was associated with donor survivorship greater than 60% suggesting that, in this setting, laser surgery remains a reasonable alternative treatment to UCO.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - July 31, 2020 Category: Perinatology & Neonatology Source Type: research
Critical Coarctation of the Aorta in Selective Fetal Growth Restriction and the Role of Coronary Stent Implantation
Conclusions: CoA specifically affects the smaller twin of growth discordant monochorionic twin pairs. Stent implantation is a feasible bridging therapy to surgery in these low birth weight neonates.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - July 27, 2020 Category: Perinatology & Neonatology Source Type: research
Tetralogy of Fallot and Outlet Ventricular Septal Defect with Anterior Malalignment Detected at Early Fetal Echocardiography
Conclusions: TOF and outlet VSD with am diagnosed before 16 weeks ’ gestation can progress in severity throughout pregnancy in over one-quarter of cases. In addition, a high proportion of cases diagnosed in the first trimester may have associated extracardiac anomalies, with a significant impact on clinical management and on the rate of early termination of preg nancy.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - July 17, 2020 Category: Perinatology & Neonatology Source Type: research
Intra-Amniotic Sildenafil Treatment Promotes Lung Growth and Attenuates Vascular Remodeling in an Experimental Model of Congenital Diaphragmatic Hernia
Conclusions: Defective embryonic pulmonary blood flow may contribute to lung maldevelopment in CDH. Enhancement of embryonic pulmonary blood flow via intra-amniotic sildenafil results in lung growth and attenuation of pulmonary vascular remodeling and may have therapeutic potential for CDH.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - July 14, 2020 Category: Perinatology & Neonatology Source Type: research
Prescriptive Reference Standards of Third-Trimester Cerebroplacental Ratio and Its Physiological Determinants
Conclusions: This study provides methodologically sound prescriptive standards and suggests that maternal body mass index is a determinant of a cutoff commonly used for decision-making.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - July 14, 2020 Category: Perinatology & Neonatology Source Type: research
