Effectiveness of ultrasound screening for placenta accreta spectrum using standard ultrasound criteria in a secondary care setting
Conclusions: Standardized ultrasound screening protocol in women at risk due to placenta previa in the third trimester was highly effective in detecting PAS in a secondary-level hospital setting. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - January 11, 2022 Category: Perinatology & Neonatology Source Type: research
Fetoscopic balloon dilation and stent placement of congenital high airway obstruction syndrome leading to successful Caesarian delivery
Conclusion: Use of repeated fetoscopy in order to relieve fetal upper airway obstruction offers the potential to minimize neonatal hypoxia, while concurrently decreasing maternal morbidity by avoiding an EXIT procedure. Use of the tracheal stent in CHAOS requires further investigation. The long-term reconstruction and respiratory support of children with CHAOS remain challenging (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - January 7, 2022 Category: Perinatology & Neonatology Source Type: research
Fetal-maternal surgery for spina bifida in a HIV-infected mother
CONCLUSION: This case shows that maternal HIV is not a priori a diagnosis that excludes fetal surgery. Rather, it might be a surrogate for movi ng towards personalized medicine and away from applying too rigorous exclusion criteria in the selection of candidates for maternal-fetal surgery. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - January 6, 2022 Category: Perinatology & Neonatology Source Type: research
Severe Fetal Symptomatic Infection from Human Cytomegalovirus following Nonprimary Maternal Infection: Report of Two Cases
Conclusion: The impact of nonprimary maternal infection on pregnancy outcome is unknown and fetal brain damage in HCMV seroimmune transmitter-mothers can occur as a consequence of maternal reinfection or reactivation for a hypotetic different role of HCMV-primed CD4+ or CD8+ T-cells in fetal brain, with progressive brain lesions coexistent in the first case and with severe unexpected anemia in the second case. A previous maternal HCMV immunity should not exempt to test anemic fetuses for such infection, nor to consider a potential transplacental transmission. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - December 30, 2021 Category: Perinatology & Neonatology Source Type: research
Severe fetal symptomatic infection from human cytomegalovirus following non-primary maternal infection: report of two cases
Conclusion
The impact of non-primary maternal infection on pregnancy outcome is unknown and fetal brain damage in HCMV seroimmune transmitter-mothers can occur as a consequence of maternal re-infection or reactiva tion for a hypotetic different role of HCMV-primed CD4+ or CD8+ T-cells in fetal brain, with progressive brain lesions coexistent in the first case and with severe unexpected anemia in the second case. A previous maternal HCMV immunity should not exempt to test anemic fetuses for such infection, nor to consider a potential transplacental transmission. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - December 30, 2021 Category: Perinatology & Neonatology Source Type: research
Outcome of Monochorionic Monoamniotic Twin Reversed Arterial Perfusion Sequence Diagnosed in the First Trimester
Conclusions: Intrauterine intervention in MOMA TRAP pregnancies significantly improves neonatal survival, although it is still associated with a substantial risk for IUD by hemodynamic complications or entanglement.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - December 13, 2021 Category: Perinatology & Neonatology Source Type: research
Placental Location in Maternal-Fetal Surgery for Myelomeningocele
Conclusions: Anterior placental location is associated with increased risk of intraoperative fetal resuscitation and increased thinning at the hysterotomy closure site. Individual institutional experiences may have varied but the aggregate data from the fMMC Consortium did not show a significant impact on the gestational age at delivery or maternal or fetal clinical outcomes. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - December 10, 2021 Category: Perinatology & Neonatology Source Type: research
Assessment of the Size and Shape of the 4-Chamber View and the Right and Left Ventricles using Fetal Speckle Tracking in Normal Fetuses at 17-24 Gestational Weeks
Conclusion: Our study provided z-score and corresponding centile calculators, 5th and 95th centile reference tables, and corresponding graphs for evaluating the size and shape of the 4CV and the right and left ventricles using 6 independent variables between 17 and 24 weeks of gestation. These results provide normal reference ranges for future studies of fetuses with pathologies that may alter the size and shape of the 4-chamber view and ventricles. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - December 10, 2021 Category: Perinatology & Neonatology Source Type: research
The Relation between Head Circumference and Mid-Pelvic Circumference: A Simple Index for Cephalopelvic Disproportion Evaluation
Conclusions: The MP-CPCI, representing the relative dimensions of the fetal HC and maternal PC, is a simple tool that can potentially distinguish between parturients at lower and higher risk of CPD. Prospective randomized studies are required to evaluate the feasibility of prenatal pelvimetry and MP-CPCI to predict the risk of CPD during labor.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - December 8, 2021 Category: Perinatology & Neonatology Source Type: research
The relation between head circumference and mid pelvic circumference: A simple index for cephalo-pelvic disproportion evaluation
Conclusions: The MP-CPCI, representing the relative dimensions of the fetal HC and maternal PC, is a simple tool that can potentially distinguish between parturients at lower and higher risk of CPD. Prospective randomized studies are required to evaluate the feasibility of prenatal pelvimetry and MP-CPCI to predict the risk of CPD during labor. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - December 8, 2021 Category: Perinatology & Neonatology Source Type: research
Prenatal Diagnosis of Aortic Coarctation: Prediction Algorithm according to Gestational Age
Conclusions: Diagnostic discrimination of anatomic predictive factors for CoA varies according to GA. Specific algorithms according to GA increase accuracy in CoA ’s prenatal prediction.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - December 6, 2021 Category: Perinatology & Neonatology Source Type: research
Significance of Low Maternal Serum ?-hCG Levels in the Assessment of the Risk of Atypical Chromosomal Abnormalities
Conclusion: Traditional cFTS can potentially identify a substantial proportion of atypical chromosomal aberrations, and women with increased NT or low maternal serum ?-hCG levels are at increased risk of having pathogenic CMA results. Our results may help clinicians and women decide whether invasive testing or prenatal cell-free DNA screening testing is more appropriate for each situation.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - December 6, 2021 Category: Perinatology & Neonatology Source Type: research
Significance of low maternal serum Β-hcg levels in the assessment of the risk of atypical chromosomal abnormalities
Conclusion: Traditional cFTS can potentially identify a substantial pro portion of atypical chromosomal aberrations, and women with increased NT or low maternal serum β-hCG levels are at increased risk of having pathogenic CMA results. Our results may help clinicians and women decide whether invasive testing or prenatal cell-free DNA screening testing are more appropri ate for each situation. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - December 6, 2021 Category: Perinatology & Neonatology Source Type: research
Methods for Monitoring Risk of Hypoxic Damage in Fetal and Neonatal Brains: A Review
Fetal, perinatal, and neonatal asphyxia are vital health issues for the most vulnerable groups in human beings, including fetuses, newborns, and infants. Severe reduction in oxygen and blood supply to the fetal brain can cause hypoxic-ischemic encephalopathy, leading to long-term neurological disorders, including mental impairment and cerebral palsy. Such neurological disorders are major healthcare concerns. Therefore, there has been a continuous effort to develop clinically useful diagnostic tools for accurately and quantitatively measuring and monitoring blood and oxygen supply to the fetal and neonatal brain to avoid se...
Source: Fetal Diagnosis and Therapy - December 6, 2021 Category: Perinatology & Neonatology Source Type: research
Reply to: Noninvasive prenatal testing for DiGeorge syndrome: is it ready for clinical practice?
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Source: Fetal Diagnosis and Therapy - November 23, 2021 Category: Perinatology & Neonatology Source Type: research
