Minimally Invasive Precise Application of Bioadhesives to Prevent IPPROM on a Pregnant Sheep Model
Discussion: This in vivo study confirms that fetoscopically induced FM defects can be sealed by the application of tissue adhesives.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 23, 2021 Category: Perinatology & Neonatology Source Type: research
Noninvasive prenatal testing for DiGeorge syndrome: is it ready for clinical practice?
None (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 22, 2021 Category: Perinatology & Neonatology Source Type: research
Use of Remifentanil Associated with Lidocaine for Feticides in Late Terminations of Pregnancy: A Randomized Clinical Trial
Conclusion: Use of remifentanil instead of sufentanil for feticide procedure did not improve time to fetal asystole. No harmful effect was observed for either maternal tolerance or interpretation of the histologic slides.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 22, 2021 Category: Perinatology & Neonatology Source Type: research
Comparison of the Performances of Middle Cerebral Artery Peak Systolic Velocity and Cardiothoracic Diameter Ratio in Predicting Fetal Anemia: Using Fetal Hemoglobin Bart ’s Disease as a Study Model
Conclusion: The performance of CTR is much better than MCA-PSV in predicting fetal anemia caused by Hb Bart ’s disease. Nevertheless, whether this can be reproduced in anemia due to other causes, like isoimmunization, is yet to be explored.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 18, 2021 Category: Perinatology & Neonatology Source Type: research
Frequent Placental SARS-CoV-2 in Patients with COVID-19-Associated Hypertensive Disorders of Pregnancy
Conclusion: Among women diagnosed with COVID-19 during pregnancy, the presence of SARS-CoV-2 in the placenta was more frequent among women suffering from PE or gestational hypertension. Furthermore, the most severe cases of HDP were associated with high placental viral load, not necessarily associated with a positive nasopharyngeal RT-PCR at delivery. Our data suggest that SARS-CoV-2 infection during pregnancy could trigger gestational hypertensive disorders through persistent placental infection and resulting placental damage.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 18, 2021 Category: Perinatology & Neonatology Source Type: research
MRI-Derived Fetal Weight Estimation in the Midpregnancy Fetus: A Method Comparison Study
Conclusions: MRI-EFW results should be interpreted with caution in midpregnancy. Despite excellent observer agreement with MRI volumetry, refinement of the EFW formula is needed in the second trimester, for the small and for the GA and preterm fetus to compensate for lower fetal densities.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 17, 2021 Category: Perinatology & Neonatology Source Type: research
Fetal Biometry: A Method for Comparing Local Curve Populations with Those from Major Reference Standards
Conclusion: This statistical method allows sonographers to assess potential differences between standard curves and local curve population, enabling a more proper identification of abnormal growth trajectories.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 15, 2021 Category: Perinatology & Neonatology Source Type: research
Care Pathway for Foetal Joint Contractures, Foetal Akinesia Deformation Sequence, and Arthrogryposis Multiplex Congenita
Conclusion: The scheduled serial structural and motor sonograpahic assessment together with follow-up examinations and genetic analysis should be tailored per prenatal centre per available resources. The multidisciplinary care pathway may pave the way to increase the detection rate and diagnosis of isolated contracture(s), TEV with underlying genetic causes, and the rare phenotypes AMC/FADS and prompt treatment after birth within expertise teams.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 12, 2021 Category: Perinatology & Neonatology Source Type: research
Care pathway for fetal joint contractures, Fetal Akinesia Deformation Sequence and Arthrogryposis Multiplex Congenita.
Discussion/conclusion
The scheduled serial structural and motor sonograpahic assessment together with follow-up examinations and genetic analysis, should be tailored per prenatal centre per available resources. The multidisciplinary care pathway may pave the way to increase detection rate and diagnosis of isolated contracture(s), talipes equinovares with underlying genetic causes and the rare phenotypes AMC/FADS and prompt treatment after birth within expertise teams. (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 12, 2021 Category: Perinatology & Neonatology Source Type: research
Why Do the Fetal Membranes Rupture after Fetoscopy?: Comments on Proposed Mechanisms and Adding the Fetus as a Potential Culprit
(Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 12, 2021 Category: Perinatology & Neonatology Source Type: research
Letter - Why do the fetal membranes rupture after fetoscopy? – Comments on proposed mechanisms and adding the fetus as a potential culprit
It has never been taken into account that the fetus itself, by being trapped within the iatrogenic openings in the amniotic membrane from a previous intervention, can tear her home to pieces. As early rupture of membranes within hours or days after percutaneous fetoscopic surgery for spina bifida occurs in less than 10% of our cases, I would attribute most ruptures later in gestation to this effect. Fetal fingers and toes fit all too easily and – with advanced gestational age (the mean age of PROM after my approach to fetoscopic spina bifida surgery occurs around 30 weeks of gestation) – the fetus becomes certainly str...
Source: Fetal Diagnosis and Therapy - November 12, 2021 Category: Perinatology & Neonatology Source Type: research
Next-Generation Sequencing Gene Panels and “Solo” Clinical Exome Sequencing Applied in Structurally Abnormal Fetuses
Conclusions: A monogenic disease was established as the underlying cause in 35% of selected fetal structural anomalies by gene panels and solo-CES.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 12, 2021 Category: Perinatology & Neonatology Source Type: research
Management of Fetal Supraventricular Tachycardia: Case Series from a Tertiary Perinatal Cardiac Center
Conclusions: Digoxin and flecainide polytherapy were well tolerated and successfully achieved rhythm and rate control in fetuses with prenatally diagnosed supraventricular tachycardia. The presence of hydrops was a poor prognostic feature.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 9, 2021 Category: Perinatology & Neonatology Source Type: research
Consensus on Training and Assessment of Competence in Performing Chorionic Villus Sampling and Amniocentesis: An International Delphi Survey
Conclusion: We established consensus among international fetal medicine experts on content to be included in a CVS/AC curriculum and on an assessment tool to evaluate CVS/AC skills. These results are important to help transition current training and assessment methods from a time- and volume-based approach to a competency-based approach which is a key step in improving patient safety and outcomes for the 2 most common invasive procedures in fetal medicine.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 8, 2021 Category: Perinatology & Neonatology Source Type: research
Reduced Growth in Non-Small for Gestational Age Fetuses from 35 Weeks of Gestation to Birth and Perinatal Outcomes
Conclusion: Fetuses with a decrease in the EPW between the ultrasound at 35 weeks of gestation and birth have a higher risk of APOs, being double in fetuses with a decrease of #x3e;40 percentile points.Fetal Diagn Ther (Source: Fetal Diagnosis and Therapy)
Source: Fetal Diagnosis and Therapy - November 2, 2021 Category: Perinatology & Neonatology Source Type: research
