The analgesic effects of dezocine in rats with chronic constriction injuries
In conclusion, the analgesic effect of dezocine on rats with CCI is dose-dependent and has little effect on the tension or contraction frequencies of intestinal smooth muscles. Our research proved the analgesic effect of dezocine in rats with CCI, and provided further insights into new therapies for NP treatment.PMID:37331802 | DOI:10.1538/expanim.23-0036 (Source: Experimental Animals)
Source: Experimental Animals - June 18, 2023 Category: Research Authors: Baojun Fu Jingjing Jiang Yuqiong Huang Source Type: research
Effects of taxifolin on aspirin-induced gastric damage in rats: macroscopic and biochemical evaluation
In conclusion, in light of the results that we obtained, 50 mg/kg taxifolin was revealed to have anti-ulcer effects. At this dose, taxifolin was able to bring COX-1 activities to a level close to those seen in healthy rats with appropriate macroscopic, oxidant/antioxidant, and biochemical parameters. Based on these results, it can be said that taxifolin may be successfully used as a more potent alternative to famotidine, which is the currently accepted treatment for aspirin-induced ulcers.PMID:37331803 | DOI:10.1538/expanim.22-0065 (Source: Experimental Animals)
Source: Experimental Animals - June 18, 2023 Category: Research Authors: Serkan Cerrah Nergiz Akbas Fatih Özcicek Renad Mammadov Durdu Altuner Halis S üleyman Seval Bulut Source Type: research
The analgesic effects of dezocine in rats with chronic constriction injuries
In conclusion, the analgesic effect of dezocine on rats with CCI is dose-dependent and has little effect on the tension or contraction frequencies of intestinal smooth muscles. Our research proved the analgesic effect of dezocine in rats with CCI, and provided further insights into new therapies for NP treatment.PMID:37331802 | DOI:10.1538/expanim.23-0036 (Source: Experimental Animals)
Source: Experimental Animals - June 18, 2023 Category: Research Authors: Baojun Fu Jingjing Jiang Yuqiong Huang Source Type: research
Effects of taxifolin on aspirin-induced gastric damage in rats: macroscopic and biochemical evaluation
In conclusion, in light of the results that we obtained, 50 mg/kg taxifolin was revealed to have anti-ulcer effects. At this dose, taxifolin was able to bring COX-1 activities to a level close to those seen in healthy rats with appropriate macroscopic, oxidant/antioxidant, and biochemical parameters. Based on these results, it can be said that taxifolin may be successfully used as a more potent alternative to famotidine, which is the currently accepted treatment for aspirin-induced ulcers.PMID:37331803 | DOI:10.1538/expanim.22-0065 (Source: Experimental Animals)
Source: Experimental Animals - June 18, 2023 Category: Research Authors: Serkan Cerrah Nergiz Akbas Fatih Özcicek Renad Mammadov Durdu Altuner Halis S üleyman Seval Bulut Source Type: research
The analgesic effects of dezocine in rats with chronic constriction injuries
In conclusion, the analgesic effect of dezocine on rats with CCI is dose-dependent and has little effect on the tension or contraction frequencies of intestinal smooth muscles. Our research proved the analgesic effect of dezocine in rats with CCI, and provided further insights into new therapies for NP treatment.PMID:37331802 | DOI:10.1538/expanim.23-0036 (Source: Experimental Animals)
Source: Experimental Animals - June 18, 2023 Category: Research Authors: Baojun Fu Jingjing Jiang Yuqiong Huang Source Type: research
Effects of taxifolin on aspirin-induced gastric damage in rats: macroscopic and biochemical evaluation
In conclusion, in light of the results that we obtained, 50 mg/kg taxifolin was revealed to have anti-ulcer effects. At this dose, taxifolin was able to bring COX-1 activities to a level close to those seen in healthy rats with appropriate macroscopic, oxidant/antioxidant, and biochemical parameters. Based on these results, it can be said that taxifolin may be successfully used as a more potent alternative to famotidine, which is the currently accepted treatment for aspirin-induced ulcers.PMID:37331803 | DOI:10.1538/expanim.22-0065 (Source: Experimental Animals)
Source: Experimental Animals - June 18, 2023 Category: Research Authors: Serkan Cerrah Nergiz Akbas Fatih Özcicek Renad Mammadov Durdu Altuner Halis S üleyman Seval Bulut Source Type: research
The analgesic effects of dezocine in rats with chronic constriction injuries
In conclusion, the analgesic effect of dezocine on rats with CCI is dose-dependent and has little effect on the tension or contraction frequencies of intestinal smooth muscles. Our research proved the analgesic effect of dezocine in rats with CCI, and provided further insights into new therapies for NP treatment.PMID:37331802 | DOI:10.1538/expanim.23-0036 (Source: Experimental Animals)
Source: Experimental Animals - June 18, 2023 Category: Research Authors: Baojun Fu Jingjing Jiang Yuqiong Huang Source Type: research
Effects of taxifolin on aspirin-induced gastric damage in rats: macroscopic and biochemical evaluation
In conclusion, in light of the results that we obtained, 50 mg/kg taxifolin was revealed to have anti-ulcer effects. At this dose, taxifolin was able to bring COX-1 activities to a level close to those seen in healthy rats with appropriate macroscopic, oxidant/antioxidant, and biochemical parameters. Based on these results, it can be said that taxifolin may be successfully used as a more potent alternative to famotidine, which is the currently accepted treatment for aspirin-induced ulcers.PMID:37331803 | DOI:10.1538/expanim.22-0065 (Source: Experimental Animals)
Source: Experimental Animals - June 18, 2023 Category: Research Authors: Serkan Cerrah Nergiz Akbas Fatih Özcicek Renad Mammadov Durdu Altuner Halis S üleyman Seval Bulut Source Type: research
Effect of felodipine on indomethacin-induced gastric ulcers in rats
Exp Anim. 2023 Jun 13. doi: 10.1538/expanim.23-0052. Online ahead of print.ABSTRACTFelodipine is a calcium channel blocker with antioxidant and anti-inflammatory properties. Researchers have stated that oxidative stress and inflammation also play a role in the pathophysiology of gastric ulcers caused by nonsteroidal anti-inflammatory drugs. The aim of this study was to investigate the antiulcer effect of felodipine on indomethacin-induced gastric ulcers in Wistar rats and compare it with that of famotidine. The antiulcer activities of felodipine (5 mg/kg) and famotidine were investigated biochemically and macroscopically i...
Source: Experimental Animals - June 14, 2023 Category: Research Authors: Nergis Akba ş Bahad ır Süleyman Renad Mammadov Mine G ülaboğlu Emin Murat Akba ş Halis S üleyman Source Type: research
Ando-Tajima Award
Exp Anim. 2023;72(Supplement):S1. doi: 10.1538/expanim.72suppl-L1.NO ABSTRACTPMID:37316215 | DOI:10.1538/expanim.72suppl-L1 (Source: Experimental Animals)
Source: Experimental Animals - June 14, 2023 Category: Research Source Type: research
Poster Presentation
Exp Anim. 2023;72(Supplement):S104-S157. doi: 10.1538/expanim.72suppl-P.NO ABSTRACTPMID:37316216 | DOI:10.1538/expanim.72suppl-P (Source: Experimental Animals)
Source: Experimental Animals - June 14, 2023 Category: Research Source Type: research
Symposium 2
Exp Anim. 2023;72(Supplement):S13-S16. doi: 10.1538/expanim.72suppl-S2.NO ABSTRACTPMID:37316217 | DOI:10.1538/expanim.72suppl-S2 (Source: Experimental Animals)
Source: Experimental Animals - June 14, 2023 Category: Research Source Type: research
