Effects of taxifolin on aspirin-induced gastric damage in rats: macroscopic and biochemical evaluation

In conclusion, in light of the results that we obtained, 50 mg/kg taxifolin was revealed to have anti-ulcer effects. At this dose, taxifolin was able to bring COX-1 activities to a level close to those seen in healthy rats with appropriate macroscopic, oxidant/antioxidant, and biochemical parameters. Based on these results, it can be said that taxifolin may be successfully used as a more potent alternative to famotidine, which is the currently accepted treatment for aspirin-induced ulcers.PMID:37331803 | DOI:10.1538/expanim.22-0065
Source: Experimental Animals - Category: Research Authors: Source Type: research