Symposium 1
Exp Anim. 2023;72(Supplement):S9-S12. doi: 10.1538/expanim.72suppl-S1.NO ABSTRACTPMID:37316233 | DOI:10.1538/expanim.72suppl-S1 (Source: Experimental Animals)
Source: Experimental Animals - June 14, 2023 Category: Research Source Type: research
Effect of felodipine on indomethacin-induced gastric ulcers in rats
Exp Anim. 2023 Jun 13. doi: 10.1538/expanim.23-0052. Online ahead of print.ABSTRACTFelodipine is a calcium channel blocker with antioxidant and anti-inflammatory properties. Researchers have stated that oxidative stress and inflammation also play a role in the pathophysiology of gastric ulcers caused by nonsteroidal anti-inflammatory drugs. The aim of this study was to investigate the antiulcer effect of felodipine on indomethacin-induced gastric ulcers in Wistar rats and compare it with that of famotidine. The antiulcer activities of felodipine (5 mg/kg) and famotidine were investigated biochemically and macroscopically i...
Source: Experimental Animals - June 14, 2023 Category: Research Authors: Nergis Akba ş Bahad ır Süleyman Renad Mammadov Mine G ülaboğlu Emin Murat Akba ş Halis S üleyman Source Type: research
Annual two-dose tetanus toxoid vaccination induces protective humoral immunity to all age groups of rhesus macaques
Exp Anim. 2023 Jun 6. doi: 10.1538/expanim.23-0040. Online ahead of print.ABSTRACTA tetanus outbreak occurred during 2014-2015 in the rhesus macaques reared in an open enclosure in our facility. As the soil of the facility was suspected to be contaminated with Clostridium tetani spores, there was a risk of further tetanus occurring among the macaques. To protect them from tetanus, a tetanus toxoid vaccination was recommended; however, the vaccinated elderly animals might not be effectively protected due to insufficient humoral immune responses. Hence, we evaluated the dynamics of antibody responses among rhesus macaques of...
Source: Experimental Animals - June 7, 2023 Category: Research Authors: Megumi Murata Anastasiia Kovba Akihisa Kaneko Mayumi Morimoto Akiyo Ishigami Takayoshi Natsume Ayaka Washizaki Takako Miyabe-Nishiwaki Juri Suzuki Hirofumi Akari Source Type: research
