Data-driven model links BMIz to gene expression in pediatric asthma
Conclusion: We found differential gene expression and implicated pathways for children with lower vs higher BMIz by asthma severity group, which could provide possible mechanisms underlying the obese-asthma phenotype. Larger studies are needed to validate this. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Dandenault, V., Hachem, N., Adcock, I. M., Andersson, L. I., Auffray, C., Chung, F. K., Dahlen, S.-E., De Meulder, B., Djukanovic, R., Howarth, P., Knowles, R. G., Krug, N., Roberts, A., Sousa, A. R., Sterk, P. J., Supple, D., Rao, N., Roberts, G., Uddin, Tags: Paediatric asthma and allergy Source Type: research
Asthma and atopy in overweight children
Conclusion: No influence of atopy in the association between asthma and obesity was verified. Further analyses of specific inflammatory markers, for evaluation of the mechanisms leading to association of obesity and asthma, as chronic diseases are warranted. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Cvejoska-Cholakovska, V., Vlashki, E., Velikj-Stefanovska, V. Tags: Paediatric asthma and allergy Source Type: research
Increasing Medical Research Council breathlessness scores are associated with longer hospital stays
Conclusion: This study is the first to identify an association between longer inpatient hospital LoS and increasing MRC score. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Karsanji, U., Brunelli, V. N., Kochovska, S., Ferreira, D., Kinchin, I., Ekström, M., Quint, J. K., Steiner, M. C., Evans, R. A., Currow, D. C. Tags: Epidemiology Source Type: research
Identifying the factors most strongly associated to breathlessness in the general population: an evaluation of 465 different factors using machine learning.
Conclusions: The identified factors could be important targets for public health interventions aiming to reduce the long-term breathlessness in the general population. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Olsson, M., Ekström, M. Tags: Epidemiology Source Type: research
Can machine learning improve predictive performance of long-term outcomes for adults with breathlessness?
Conclusion: Our results suggest ML methods may not always improve predictive performance of models for health research and LR can be sufficient. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Karsanji, U., Steiner, M. C., Lawson, C. A., Petherick, E., Evans, R. A., Richardson, M. Tags: Epidemiology Source Type: research
Sense of control association to breathlessness: an analysis of 30,000 men and women in the general population.
Conclusions: Sense of control can be important to consider for non-pharmacological interventions for breathlessness. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Olsson, M., Ekström, M. Tags: Epidemiology Source Type: research
The role of Low-Dose CT scan in the early diagnosis of malignant neoplasms of different localization.
Conclusion: The significantly high frequency of detection of malignant neoplasms of various localizations during the Low-Dose CT scan suggests that the COVID-19 pandemic has increased the understanding of the feasibility of this imaging method as a screening for malignant neoplasms of various organs. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Kovchun, A., Kovchun, V., Kachkovska, V., Prystupa, L. Tags: Epidemiology Source Type: research
Post-pandemic seasonal dynamics in the frequency of hospitalized exacerbations and triggers in COPD
Conclusion: Typical seasonal variation in AECOPD admissions was lost during 2022, following two years of the pandemic. It remains to be seen if seasonality will return in future years. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Aung, H. W., Aung, A., Mcauley, H., Elneima, O., Flynn, C., Thornton, T., Evans, H., Brightling, C., Greening, N. Tags: Epidemiology Source Type: research
Epidemiology of Respiratory Syncytial Virus in Germany before and during covid-19 pandemic
Conclusion: Our results indicate that the complete lack of cases from 05/2020 to 06/2021 stimulated a catch-up effect in season 2021/22 with significantly higher RSV incidence and associated with lower disease severity, especially in infants. The early onset of the RSV season during the pandemic should be considered for future vaccination strategies. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Loerch, S., Erdnuess, F., Reineke, T., Frerich, B., Kamin, W., Loerch, S. Tags: Epidemiology Source Type: research
Impact of the Covid19 pandemic on survival of patients with home mechanical ventilation(HMV)
Conclusions: The pandemic represented an increase in the mortality of HMV patients. Apart from the direct effect of the infection, a disruption care may have favored this increase. To minimize it, it is important to create structures that allow adequate monitoring, such as telemedicine. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Marin Muniz, A., Cordoba Izquierdo, A., Sarasate Azkona, M., Farrero Munoz, E., Vidales Sepulveda, Z., Mateu Gomez, L., Santos Perez, S., Prats Soro, E. Tags: Epidemiology Source Type: research
The effects Covid-19 had on the children of health care professionals
Conclusions: The children of healthcare workers were affected more than their age range by Covid-19. Thus, we must be available to meet their needs in such times. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Havlucu, E., Özkul, A., Kızılırmak, D. Tags: Epidemiology Source Type: research
Blood biomarkers and biological age among patients with long COVID
Conclusion: Long COVID phenotypes correspond to differences in blood biomarkers and biological ageing. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Subramanian, A., Nirantharakumar, K., Lord, J., Wraith, D. C., Haroon, S. Tags: Epidemiology Source Type: research
The role of booster vaccination in decreasing COVID-19 age-adjusted case fatality rate: evidence from 32 countries
Conclusions: Boosters reduce ad-CFRs, but addressing country-specific risks and implementing joint intervention strategies are also crucial. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Gao, J., Zhou, C., Wheelock, A., Zhang, C., Ma, J., Dong, K., Li, Z., Liang, W., Xu, L. Tags: Epidemiology Source Type: research
SARS-CoV-2 and risk of psychiatric hospital admission and use of psychopharmaceuticals: A nationwide registry study of 4,585,083 adult Danish citizens
Conclusions: We found a signal of increased use of psychoactive medication, specifically benzodiazepines, among SARS-CoV-2 positive persons, but the incidence of psychiatric admissions did not increase, possibly simply because of relevant pharmacological treatment, which may have prevented some admissions. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Romer, V., Sivapalan, P., Eklöf, J., Dam Nielsen, S., Barrella Harboe, Z., Biering-Sorensen, T., Itenov, T., Staehr Jensen, J.-U. Tags: Epidemiology Source Type: research
The cost of primary care consultations associated with long COVID in non-hospitalised adults: a retrospective cohort study using UK primary care data
ConclusionsThe costs of primary care consultationsassociated with long COVID in non-hospitalised adults are substantial. Costs are significantly higher among those diagnosed with long COVID, those with long COVID symptoms,older adults, females, and those with obesity and comorbidities. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Tufts, J., Zemedikun, D., Subramanian, A., Guan, N., Gokhale, K., Myles, P., Williams, T., Marshall, T., Calvert, M., Matthews, K., Nirantharakumar, K., Jackson, L., Haroon, S. Tags: Epidemiology Source Type: research
