Nobel and Charcot in Paris: A Brazilian Connection?
Eur Neurol (Source: European Neurology)
Source: European Neurology - March 17, 2021 Category: Neurology Source Type: research
Prestroke Statins Improve Prognosis of Atrial Fibrillation-Associated Stroke through Increasing Suppressor of Cytokine Signaling-3 Levels
Conclusion: Our data suggested that the prestroke use of statins improved the clinical outcomes in AIS patients with AF by upregulating the level of SOCS-3 and reducing the plasma MMP-9 level.Eur Neurol (Source: European Neurology)
Source: European Neurology - March 8, 2021 Category: Neurology Source Type: research
Drip-and-Ship Model for Thrombectomy in Stroke Patients with Large-Vessel Occlusion
Conclusions: The “drip-and-ship” model has the potential to be a feasible model for patients with LVO in the anterior circulation to undergo endovascular treatment. Further large-scale prospective studies are warranted to confirm these findings.Eur Neurol (Source: European Neurology)
Source: European Neurology - March 5, 2021 Category: Neurology Source Type: research
Message from the Editor
Eur Neurol (Source: European Neurology)
Source: European Neurology - March 3, 2021 Category: Neurology Source Type: research
The Art of Charcot: An Outstanding Caricaturist
Jean-Martin Charcot is considered the father of modern neurology; alongside his work as a physician, professor, and researcher in this area, he was also artistically gifted with a taste for caricature. This historical note summarizes 8 caricatures by Charcot that exhibit a mixture of humor, satire, irony, and sarcasm.Eur Neurol (Source: European Neurology)
Source: European Neurology - February 16, 2021 Category: Neurology Source Type: research
Contents Vol. 83, 2020
Eur Neurol 2020;83:I –VIII (Source: European Neurology)
Source: European Neurology - January 29, 2021 Category: Neurology Source Type: research
Increased Number of Perivascular CD20-Positive B Lymphocytes in the Neuropathology of CLIPPERS: Findings of 6 Patients from Mainland China
Conclusion: Our reports highlight the importance of neuropathological examinations when encountering atypical imaging manifestations, such as unilateral and large nodular Gd+ lesions, in order to establish a final diagnosis of CLIPPERS. In addition, the lymphocytic infiltration in the lesions of CLIPPERS may be dominated by CD20+ B cells instead of CD3+ T cells.Eur Neurol (Source: European Neurology)
Source: European Neurology - January 26, 2021 Category: Neurology Source Type: research
Effect of Argatroban Injection on Clinical Efficacy in Patients with Acute Cerebral Infarction: Preliminary Findings
Conclusion: Argatroban injection is effective in the treatment of acute cerebral infarction, which can significantly improve the hemorheology of patients with good safety.Eur Neurol (Source: European Neurology)
Source: European Neurology - January 21, 2021 Category: Neurology Source Type: research
The Potential of Neurofilament Light as a Biomarker in Alzheimer ’s Disease
Background: Alzheimer ’s disease (AD) is the most common neurodegenerative disease characterized by progressive memory loss and cognitive impairment. In 2011, the National Institute on Aging and Alzheimer’s Association (NIA-AA) Research Framework has proposed to use biomarkers to diagnose AD in living persons. AD cor e biomarkers show high diagnostic specificity in distinguishing AD from healthy control subjects, but have little additional value for prognosis or stage of disease.Summary: With the update of detection methods and techniques, other AD biomarkers have been discovered. Neurofilament light (NFL) is currently...
Source: European Neurology - January 21, 2021 Category: Neurology Source Type: research
Botulinum Toxin in WW2 German and Allied Armies: Failures and Myths of Weaponization
Botulinum toxin is nowadays approved as an effective medication for various neurological disorders. The extreme toxicity of this toxin-inducing botulism, a severe lethal muscle-paralyzing illness, has been well known since the seminal works of the end of the 19th century. Because of this toxicity, botulinum toxin was one of the first agents to be considered for use as a biological weapon. The Second World War was a crucial period for the first attempts to weaponize this toxin even if many unknown factors about botulinum toxin still existed at the outbreak of the war. Using documents from the British National Archives and o...
Source: European Neurology - January 20, 2021 Category: Neurology Source Type: research
Detection of Epileptic Seizure Using Pretrained Deep Convolutional Neural Network and Transfer Learning
Conclusion: The proposed automatic identification and classification model can help in the early diagnosis of epilepsy, thus providing the opportunity for effective early treatment.Eur Neurol (Source: European Neurology)
Source: European Neurology - January 8, 2021 Category: Neurology Source Type: research
Association between Pre-Existing Coronary Artery Disease and 5-Year Mortality in Stroke Patients with High-Grade Carotid Artery Stenosis
Conclusion: Pre-existing CAD was associated with an increased risk of 5-year mortality in acute IS patients with high-grade CAS. Intensive treatment for the pre-existing CAD may reduce long-term mortality in acute IS patients with high-grade CAS.Eur Neurol (Source: European Neurology)
Source: European Neurology - December 23, 2020 Category: Neurology Source Type: research
Stroke Care in the First Affiliated Hospital of Chengdu Medical College during the COVID-19 Outbreak
Coronavirus disease-2019 (COVID-19) has become a pandemic disease globally. The First Affiliated Hospital of Chengdu Medical College has adopted telestroke to make stroke care accessible in remote areas. During the period January 2020 to March 2020, there was no COVID-19 case reported in our stroke center. A significant reduction of stroke admission was observed between the ischemic stroke group (235 vs. 588 cases) and the intracerebral hemorrhage group (136 vs. 150 cases) when compared with the same period last year (p #x3c; 0.001). The mean door-to-needle time (DNT) and door-to-puncture time (DPT) was 62 and 124 min, res...
Source: European Neurology - December 18, 2020 Category: Neurology Source Type: research
History of the Concept of Tuberculous Meningitis
This article reviews the writings in Scotland and France that marked the history of the identification of this infectious entity. From John Paisley in 1734 to Robert Whytt in 1738, from Marcellin Chardel in 1799 and L.P. Coll inet in 1802 to Isidore Bricheteau in 1814 and Jean-Louis Brachet in 1818, and then Victor Le Diberder in 1837 and Isidore Valleix in 1838, unknown and forgotten physicians outnumber the famous masters in bringing about the progress and knowledge that enabled this frequent and consistently fatal dis ease in the 19th century to be accurately diagnosed and in most cases cured in the 20th century.Eur Neu...
Source: European Neurology - December 16, 2020 Category: Neurology Source Type: research
Time Trends in Intracerebral Hemorrhage Associated with Oral Anticoagulation and Its Risks Factors in Spain from 2008 to 2015
Conclusions: The incidence of ICH-OAC is increasing in our country. It might at least be partly explained by aging of the population, with mean age at presentation being higher in the last years.Eur Neurol (Source: European Neurology)
Source: European Neurology - December 15, 2020 Category: Neurology Source Type: research
