“You Are Older, although You Do Not Know That”: Time, Consciousness, and Memory in “A Kind of Alaska” by Harold Pinter (1930–2008)
This article analyzes how Pinter’s drama investigated the mysterious and fascinating relationship between time, memory, and consciousness. The term “awakenings,” chosen by Sacks himself, clearly refers to the restoration of voluntary motor function in patients with postencephalitic parkinsonism who responded to levodopa. However, it also suggests that these patients had an impairment of awareness. Actually, beyond the acute phase, subjects with postencephal itic parkinsonism were not sleeping but severely akinetic and therefore probably aware of the passage of time. Oliver Sacks probably did not entirely recognize th...
Source: European Neurology - July 20, 2021 Category: Neurology Source Type: research
The Effect of Water-Based Therapy Compared to Land-Based Therapy on Balance and Gait Parameters of Patients with Stroke: A Systematic Review
Conclusion: Findings from meta-analysis support the effectiveness of land-based therapy in the improvement of balance and gait parameters of patients with stroke. However, the evidence for water-based therapy continues to be limited, and higher quality studies are required to determine the effectiveness of water-based therapy on patients with stroke, particularly on balance and gait.Eur Neurol (Source: European Neurology)
Source: European Neurology - July 16, 2021 Category: Neurology Source Type: research
Validation of the Finnish Version of the Unified Dyskinesia Rating Scale
Conclusion: The overall factor structure of the Finnish version was consistent with that of the reference standard, and it can be designated as the official version of the UDysRS for Finnish speaking populations.Eur Neurol (Source: European Neurology)
Source: European Neurology - July 14, 2021 Category: Neurology Source Type: research
Clinical Course of Migraine during Strict Quarantine due to SARS-CoV-2: Effect of Psychiatric Comorbidities in a Clinical Cohort
Conclusion: During the SARS-CoV-2 pandemic, depression, anxiety, and the deterioration of sleep quality influenced the probability of progression from episodic migraine to chronic migraine.Eur Neurol (Source: European Neurology)
Source: European Neurology - July 9, 2021 Category: Neurology Source Type: research
Do Not Replace Personal Patient/Doctor Interactions by Electronic Visits in Myotonic Dystrophy Patients
Eur Neurol (Source: European Neurology)
Source: European Neurology - July 1, 2021 Category: Neurology Source Type: research
Secondary Trigeminal Neuralgia: Do Not Forget the Pontine Ischemic Infarction
Eur Neurol (Source: European Neurology)
Source: European Neurology - July 1, 2021 Category: Neurology Source Type: research
On the Threshold of Scientific Medicine: Gerard van Swieten and His Perception of the Pathophysiology in Traumatic Brain Injury
Gerard van Swieten (1700 –1772), famous pupil of Professor Herman Boerhaave (1668–1738) of Leiden University and personal physician of Austrian Habsburg Empress Maria Theresa (1717–1780). Herman Boerhaave was a renowned Dutch physician inside and outside Europe in the 18th century. He was not only appointed professor in medicine, chemistry, and botany but also a chancellor of the Leiden University in 1714 and published his well-knownAphorismi de cognoscendis et curandis morbis in 1709. Gerard van Swieten commented upon Boerhaave ’s aphorisms and demonstrated actual knowledge, less well-known among the medical commu...
Source: European Neurology - July 1, 2021 Category: Neurology Source Type: research
Volatile Organic Compounds to Identify Infectious (Bacteria/Viruses) Diseases of the Central Nervous System: A Pilot Study
Conclusions: Ethylene oxide and phenol may be potential biomarkers to distinguish bacterial ME and viral ME. VOC analysis of CSF may be used as a supporting tool for clinical diagnosis.Eur Neurol (Source: European Neurology)
Source: European Neurology - June 28, 2021 Category: Neurology Source Type: research
Association of Anxiety and Depressive Symptoms with Memory Function following Traumatic Brain Injury
Conclusion: More depressive symptoms rather than anxiety symptoms and less years of education are significant predictors for posttraumatic memory dysfunction.Eur Neurol (Source: European Neurology)
Source: European Neurology - June 28, 2021 Category: Neurology Source Type: research
Diagnostic Validity of the Sleep Condition Indicator to Screen for Diagnostic and Statistical Manual-5 Insomnia Disorder in Patients with Parkinson ’s Disease
Conclusion: The SCI can be used as a valid and reliable screener for DSM-5 insomnia disorder in PD patients. Due to its short length, it is useful in both clinical practice and scientific research.Eur Neurol (Source: European Neurology)
Source: European Neurology - June 28, 2021 Category: Neurology Source Type: research
Longitudinal Timed Up and Go Assessment in Amyotrophic Lateral Sclerosis: A Pilot Study
Progressive loss of walking ability in amyotrophic lateral sclerosis (ALS) has been scarcely studied as a potential predictive factor for survival in motor neuron disease. We aimed to assess the progression of gait decline and its association with mortality in ALS using the Timed Up and Go test (TUG). Patients were followed up prospectively at the Centre for ALS and Related Disorders in Geneva University Hospitals between 2012 and 2016. The TUG was performed at baseline and subsequent evaluations occurred every 3 months. At inclusion, patients were classified as unable to perform the TUG, “slow TUG” (#x3e;10.6 s), and ...
Source: European Neurology - June 24, 2021 Category: Neurology Source Type: research
Does Chronic Kidney Disease Have an Impact on the Use of Oral Anticoagulants after Stroke? An Observational Follow-Up Study
Conclusion: Our results show that chronic kidney disease was not the main factor in the decision to withhold oral anticoagulation in patients with recent stroke/TIA and AF.Eur Neurol (Source: European Neurology)
Source: European Neurology - June 24, 2021 Category: Neurology Source Type: research
Pre- and Postictal Changes in the Innate Immune System: Cause or Effect?
Conclusion: Our study argues for a role of the innate immune system in the pre- and postictal phases. NK cells might be involved in preictal changes or be altered as an epiphenomenon in the immediate preictal interval.Eur Neurol (Source: European Neurology)
Source: European Neurology - June 17, 2021 Category: Neurology Source Type: research
A Questionnaire-Based Study on Clinical REM Sleep Behavior Disorder and Subtypes in Multiple System Atrophy
Conclusion: In our study, the prevalence of clinical RBD is unrelated to the subtypes of MSA. The onset of clinical RBD during the premotor period was not different between subtypes of MSA. However, we found that the severity of RBD occurring before the motor symptoms was more than that occurring after the motor symptoms in MSA-C patients. Our results showed that MSA-P and MSA-C patients may have a probable indicator for the similar pathologic mechanism of the disease and its sleep problems.Eur Neurol (Source: European Neurology)
Source: European Neurology - June 16, 2021 Category: Neurology Source Type: research
Association of the Irregular 3-Dimensional Shape of White Matter Hyperintensities with Cognitive Function
Conclusion: An irregular WMH shape may be associated with the high cerebrovascular component of cognitive impairment and the diagnosis and low cognitive flexibility of SVD, which may improve the prediction of SVD diagnosis when used in combination with WMH volume.Eur Neurol (Source: European Neurology)
Source: European Neurology - June 2, 2021 Category: Neurology Source Type: research
