Association of Dietary Patterns with Parkinson ’s Disease: A Cross-Sectional Study Based on the United States National Health and Nutritional Examination Survey Database
Conclusions: The odds of PD decreased by higher MeDi adherence and increased by higher Western pattern adherence, especially sweets intake in this pattern, suggesting population ≥50 years should adhere to MeDi pattern and decrease the adherence to Western pattern, reducing the intake of sweets.Eur Neurol (Source: European Neurology)
Source: European Neurology - December 5, 2022 Category: Neurology Source Type: research
An Association Study of < b > < i > ESR < /i > < /b > 1 – < b > < i > Xba < /i > < /b > I and < b > < i > Pvu < /i > < /b > II Gene Polymorphism in Migraine Susceptibility in the Jammu Region
Conclusion: In conclusion,ESR1-XbaI polymorphism is significantly associated with migraine risk including both subtypes (MA and MO) in the North Indian population of Jammu.Eur Neurol (Source: European Neurology)
Source: European Neurology - November 25, 2022 Category: Neurology Source Type: research
Contents Vol. 85, 2022
Eur Neurol 2022;85:I –VI (Source: European Neurology)
Source: European Neurology - November 9, 2022 Category: Neurology Source Type: research
Acknowledgement to Reviewers
Eur Neurol 2022;85:494 (Source: European Neurology)
Source: European Neurology - November 9, 2022 Category: Neurology Source Type: research
Integrin β1 and the Repair after Nervous System Injury
Background: Integrin β1, as a member of the adhesion molecule family, is widely distributed in many kinds of cells and participates in multiple biological functions of the nervous system, including cytoskeleton reorganization, axon growth, and inflammatory injury.Summary: After nervous system injury, integrin β1 expressed by microglia is mainly involved in promoting inflammatory damage; integrin β1 expressed by astrocytes plays an important role in axon regeneration; integrin β1 expressed by endothelial cells mainly participates in vascular remodeling. We concluded that the function of integrin β1 de pends on the loca...
Source: European Neurology - October 25, 2022 Category: Neurology Source Type: research
Effectiveness of Progressive Resistance Training in Parkinson ’s Disease: A Systematic Review and Meta-Analysis
Conclusions: This meta-analysis revealed that PRT had positive effects on freezing of gait, muscle strength, and improved quality of life during rehabilitation in PD patients.Eur Neurol (Source: European Neurology)
Source: European Neurology - October 20, 2022 Category: Neurology Source Type: research
Migraine, Words and Fiction. Book Review
naEur Neurol (Source: European Neurology)
Source: European Neurology - October 3, 2022 Category: Neurology Source Type: research
Effects of Direct Oral Anticoagulants ’ Nonrecommended Dose in Atrial Fibrillation: A Meta-Analysis
Background: The efficacy and safety profiles of nonrecommended direct oral anticoagulant (DOAC) doses in patients with nonvalvular atrial fibrillation (NVAF) are still undefined.Summary: We searched for randomized controlled trials and observational studies that compared nonrecommended versus recommended doses of DOACs, published up to December 2021. Primary study outcomes were ischemic stroke/transient ischemic attack/systemic embolism (IS/TIA/SE) and major bleeding (MB). All-cause mortality was a secondary outcome. We determined pooled odds ratios (ORs) between groups of patients with a random-effect model. Twenty-three ...
Source: European Neurology - September 13, 2022 Category: Neurology Source Type: research
Chorea: An Update on Genetics
Background: Chorea may be present in a number of diseases including hereditary disorders. Major advances have occurred in our understanding of the genetic background of those disorders, and the present short review aims at highlighting the most salient ones.Summary: Chorea is one of the major manifestations of Huntington ’s disease. However, there are a number of other diseases, in which chorea is present as well and their list is in constant increase thanks to the availability of advanced molecular genetic diagnostic techniques. Finding of new genes followed by the investigation of further cases with part of the phenoty...
Source: European Neurology - September 1, 2022 Category: Neurology Source Type: research
Aspiration versus Stent Retriever Thrombectomy in Posterior Circulation Stroke: A Systematic Review and Meta-Analysis
Conclusion: This study provides preliminary evidence for improved morbidity and mortality outcomes in posterior circulation stroke patients undergoing aspiration-based thrombectomies as compared to stent retriever-based thrombectomy. The study also provides evidence for improved endovascular outcomes for patients undergoing aspiration-based thrombectomies. The findings from this study can have implications in developing awareness among neurosurgeons for stratifying patients to manage posterior circulation stroke according to the risks associated with aspiration and stent retriever-based thrombectomies.Eur Neurol (Source: European Neurology)
Source: European Neurology - August 10, 2022 Category: Neurology Source Type: research
Treatments in Ischemic Stroke: Current and Future
Background and Aim: Despite progress made over the last 30 years, stroke is still a leading cause of disability and mortality; likewise, its burden is expected to increase over the next decades, due to population growth and aging. The development of drugs with better safety-efficacy profiles as well as strategies able to improve ischemic stroke management from the pre-hospital setting is needed.Summary: The pathophysiology of ischemic stroke involves multiple pathways resulting in cerebral artery obstruction and brain tissue ischemia. To date, the only approved drug for acute ischemic stroke is intravenous thrombolytic alt...
Source: European Neurology - August 2, 2022 Category: Neurology Source Type: research
Cerebral Gray Matter Volume Changes in Patients with Neuropathic Pain from Total Brachial Plexus Injury
Conclusion: Total brachial plexus injury patients with chronic pain have widespread regions of gray matter atrophy and hypertrophy. The only positive correlation was observed between pain severity and rGMV changes in one specific region, suggesting that nociceptive stimuli trigger a variety of nonpain-specific processes, which confirms the multidimensional nature of pain.Eur Neurol (Source: European Neurology)
Source: European Neurology - July 28, 2022 Category: Neurology Source Type: research
What Is Different about Teratoma-Associated Anti-LGI1 Encephalitis? A Long-Term Clinical and Neuroimaging Case Series
Conclusion: In our series, anti-LGI1 encephalitis included common clinical features in our series: rapidly progressive dementia, faciobrachial dystonic seizures, behavioral disorders, hyponatremia, hippocampal hyperintensity on magnetic resonance imaging, and residual cognitive deficit. We observed some differences (chronic anxiety and status epilepticus) in our case with teratoma, but a larger accumulation of cases is needed to improve our knowledge base.Eur Neurol (Source: European Neurology)
Source: European Neurology - July 27, 2022 Category: Neurology Source Type: research
Ferritin and Neurotoxicity: A Contributor to Deleterious Outcomes for Subarachnoid Hemorrhage
Background: Ferritin is a protein that is critical for storing iron. Ferritin has recently been shown to play a role in iron homeostasis, immunomodulation, inflammation, and antioxidation. Previously, it was believed that ferritin was exclusively an intracellular peptide. However, there is significant evidence that ferritin is also in the serum, cerebral spinal fluid, and synovial fluid.Summary: Within the brain, ferritin can bind to oligodendrocytes adjacent to the blood-brain barrier to allow a docking point for ferritin to be engulfed by microglia in the brain parenchyma. When iron supplies in the brain are low, the lys...
Source: European Neurology - July 22, 2022 Category: Neurology Source Type: research
Clinical and Preclinical Neuroimaging Changes in Spinocerebellar Ataxia Type 12: A Study of Three Chinese Pedigrees
Conclusions: We first found that hypometabolism in the cerebral cortex, but not cerebellum, is an early and prominent change in SCA12. The integrity of presynaptic dopaminergic neurons remains largely spared during the whole disease process.Eur Neurol (Source: European Neurology)
Source: European Neurology - July 19, 2022 Category: Neurology Source Type: research