Long-term results of His bundle pacing and atrioventricular node ablation: is this the future?
This editorial refers to ‘Long-term performance and risk factors analysis after permanent His-bundle pacing and atrioventricular node ablation in patients with atrial fibrillation and heart failure’, by L. Suet al., on pages ii19--ii26. (Source: Europace)
Source: Europace - December 28, 2020 Category: Cardiology Source Type: research
Long-term performance and risk factors analysis after permanent His-bundle pacing and atrioventricular node ablation in patients with atrial fibrillation and heart failure
ConclusionHis-bundle pacing combined with AVN ablation was effective in patients with AF and drug-refectory HF. High PASP, high Scr, or low LVEF at baseline was independent predictors of composite endpoint of all-cause mortality or HFH. (Source: Europace)
Source: Europace - December 28, 2020 Category: Cardiology Source Type: research
Feasibility and efficacy of left bundle branch area pacing in patients indicated for cardiac resynchronization therapy
ConclusionThe present study demonstrates the clinical feasibility of LBBAP in CRT-indicated patients. Left bundle branch area pacing generated narrow QRSd and led to reversal remodelling of LV with improvement in cardiac function. LBBAP may be an alternative to CRT in patients with failure of LV lead placement and a first-line option in selected patients such as those with LBBB and heart failure. (Source: Europace)
Source: Europace - December 28, 2020 Category: Cardiology Source Type: research
Lead performance and clinical outcomes of patients with permanent His-Purkinje system pacing: a single-centre experience
ConclusionHis-Purkinje system pacing produced favourable electrical synchrony and improved cardiac function in patients with heart failure. Left bundle branch pacing showed superior pacing parameters over HB pacing. Lead micro-displacement with changes in paced QRS morphology posts a concern in LBB pacing. (Source: Europace)
Source: Europace - December 28, 2020 Category: Cardiology Source Type: research
Electrical characteristics of pacing different portions of the His bundle in bradycardia patients
ConclusionThis study demonstrates that vHBP features a low and stable pacing capture threshold and high R-wave amplitude, suggesting better pacing mode management and battery longevity can be achieved by HBP in the ventricular side. (Source: Europace)
Source: Europace - December 28, 2020 Category: Cardiology Source Type: research
Novel left ventricular cardiac synchronization: left ventricular septal pacing or left bundle branch pacing?
This article reviews the clinical application and differences between LVSP and LBBP. Compared with LVSP, LBBP has strict criteria for left conduction system capture and lead location. In addition to LV septal capture it also stimulates the proximal left bundle branch, resulting in rapid and physiological LV activation. With a uniformity and standardization of the implant procedure and definitions, it may be possible to achieve widespread application of this form of physiological pacing. (Source: Europace)
Source: Europace - December 28, 2020 Category: Cardiology Source Type: research
Foreword 10th Theo Rossi Di Montelera Forum on computer simulation and experimental assessment of cardiac function: towards the digital twin
What ’s new?For many years, computer modelling of physiological principles underlying the behaviour of the heart, which started during the 1970 ’s, was considered more as a hobby of engineers than as a potentially important tool for understanding how properties of microscopical components determine the macroscopical behaviour of the organ.The papers in this supplement demonstrate that computer modelling has become an essential tool for un derstanding (patho)physiological behaviour of the heart and that it is well on its way to become an essential instrument in patient management. (Source: Europace)
Source: Europace - December 26, 2020 Category: Cardiology Source Type: research
Paradigm shifts in electrophysiological mechanisms of atrial fibrillation
AbstractDetermining the sequence of activation is a major source of information for understanding the electrophysiological mechanism(s) of atrial fibrillation (AF). However, the complex morphology of the electrograms hampers their analysis, and has stimulated generations of electrophysiologists to develop a large variety of technologies for recording, pre-processing, and analysis of fibrillation electrograms. This variability of approaches is mirrored by a large variability in the interpretation of fibrillation electrograms and, thereby, opinions regarding the basic electrophysiological mechanism(s) of AF vary widely. Mult...
Source: Europace - December 24, 2020 Category: Cardiology Source Type: research
List of Reviewers
Editor-in-Chief Professor Gerhardt Hindricks and the Editorial Team would like to thank the reviewers who supported the journal in 2019-2020. (Source: Europace)
Source: Europace - December 23, 2020 Category: Cardiology Source Type: research
A case of re-entrant ventricular tachycardia arising from the vicinity of the his bundle that was successfully ablated from the non-coronary aortic sinus of valsalva
Idiopathic ventricular arrhythmia arising from the vicinity of the His bundle (HB) can be ablated from the non-coronary aortic sinus of Valsalva (NCS). However, no such case of re-entrant ventricular tachycardia (VT) has been reported. (Source: Europace)
Source: Europace - December 22, 2020 Category: Cardiology Source Type: research
Understanding important factors for arrhythmogenicity associated with transcatheter aortic valve implantation including left bundle branch block
We read with interest the multicentre prospective study by Muntan é-Carolet al that demonstrated new-onset left bundle branch block (LBBB) was an indicator of high arrhythmogenicity after transcathether aortic valve implantation (TAVI).1 Whilst new tachyarrhythmic events were distributed evenly within the 2-year follow-up the majority of new high-degree atrioventricular block leading to pacemaker (PPM) implantation occurred in the initial months. (Source: Europace)
Source: Europace - December 22, 2020 Category: Cardiology Source Type: research
Vanishing left bundle branch potential during physiological pacing
A 67-years-old gentleman had undergone left bundle branch pacing for symptomatic intra-Hisian block (Panel A). Left bundle branch potential (LBB-Po) was noted after six rapid rotations (Panel B). Additional rotations were given as the peak left ventricular activation time was not short and constant, which resulted in the disappearance of potential. As the unipolar pacing threshold was 0.3 V at 0.5 ms pulse-width and unipolar impedance 620 Ω with LBB current of injury (Type II LBB-COI), we decided to wait before considering lead repositioning for a probable septal perforation. Gradual re-appearance of LBB-Po was n...
Source: Europace - December 17, 2020 Category: Cardiology Source Type: research
Efficacy and safety of left atrial appendage electrical isolation during catheter ablation of atrial fibrillation: an updated meta-analysis
ConclusionAt long-term follow-up, LAAEI led to a significantly higher improvement in freedom from all-atrial arrhythmia recurrence in patients with non-paroxysmal AF, when compared to standard ablation alone. Importantly, this benefit was achieved without an increased risk of acute procedural complications or cerebral thromboembolic events. (Source: Europace)
Source: Europace - December 16, 2020 Category: Cardiology Source Type: research
The interpretation of CHA2DS2-VASc score components in clinical practice: a joint survey by the European Heart Rhythm Association (EHRA) Scientific Initiatives Committee, the EHRA Young Electrophysiologists, the Association of Cardiovascular Nursing and Allied Professionals, and the European Society of Cardiology Council on Stroke
In conclusion, this survey revealed overall good adherence to the correct definition of each component in scoring of the ‘C’, ‘H’, and ‘V’ elements of the CHA2DS2-VASc score, although the variation in their interpretations warrants further clarifications. The preferred referencing resources to calculate the score varied among different healthcare professionals. Guideline education to healthcare professionals and updated and unified online/mobile scoring tools are suggested to improve the accuracy in scoring the CHA2DS2-VASc score. (Source: Europace)
Source: Europace - December 12, 2020 Category: Cardiology Source Type: research
Comparative data on left atrial appendage occlusion efficacy and clinical outcomes by age group in the Amplatzer ™ Amulet™ Occluder Observational Study
ConclusionsDespite the increased risk for ischaemic stroke with increasing age in AF patients, LAAO reduced the risk for ischaemic stroke compared with the predicted rate across all age groups without differences in procedural SAEs. (Source: Europace)
Source: Europace - December 6, 2020 Category: Cardiology Source Type: research
