High-density biatrial activation mapping during typical atrial flutter after bicavopulmonary bypass
(Source: Europace)
Source: Europace - August 30, 2016 Category: Cardiology Authors: Maury, P., Capellino, S., Hascoet, S. Tags: CASE EXPRESS REPORTS Source Type: research

Five-year efficacy of pulmonary vein antrum isolation as a primary ablation strategy for atrial fibrillation: a single-centre cohort study
Conclusion Five-year freedom of atrial tachyarrhythmia could be achieved by PVAI as primary ablation strategy in 58.3% of patients. Additional substrate modification only moderately increased overall success. (Source: Europace)
Source: Europace - August 30, 2016 Category: Cardiology Authors: Teunissen, C., Kassenberg, W., van der Heijden, J. F., Hassink, R. J., van Driel, V. J. H. M., Zuithoff, N. P. A., Doevendans, P. A., Loh, P. Tags: Ablation for atrial fibrillation Source Type: research

Cystic tumour of the atrioventricular node: can an electrophysiological study predict sudden death?
(Source: Europace)
Source: Europace - August 30, 2016 Category: Cardiology Authors: Ueda, K., Tagusari, O., Kasao, M. Tags: CASE EXPRESS REPORTS Source Type: research

Von Willebrand factor is associated with atrial fibrillation development in ischaemic patients after cardiac surgery
Conclusion Plasma vWF levels are associated with tissue fibrosis in patients undergoing cardiac surgery and with post-surgical AF development in ischaemic patients. These findings suggest an association among vWF levels, atrial remodelling, and AF development. It is supported by higher vWF expression in right atrial tissue in ischaemic patients, who developed post-surgical AF. (Source: Europace)
Source: Europace - August 30, 2016 Category: Cardiology Authors: Hernandez-Romero, D., Lahoz, A., Roldan, V., Jover, E., Romero-Aniorte, A. I., Martinez, C. M., Jara-Rubio, R., Arribas, J. M., Garcia-Alberola, A., Canovas, S., Valdes, M., Marin, F. Tags: Atrial fibrillation Source Type: research

A useful irrigated tip to cannulate distal coronary sinus
(Source: Europace)
Source: Europace - August 30, 2016 Category: Cardiology Authors: Fedida, J., Lepiece, C., Knecht, S. Tags: CASE EXPRESS REPORTS Source Type: research

Effectiveness and safety of dabigatran versus acenocoumarol in 'real-world patients with atrial fibrillation
Conclusion In ‘real-world’ patients with AF, dabigatran appears to be as effective, but significantly safer than acenocoumarol. (Source: Europace)
Source: Europace - August 30, 2016 Category: Cardiology Authors: Korenstra, J., Wijtvliet, E. P. J., Veeger, N. J. G. M., Geluk, C. A., Bartels, G. L., Posma, J. L., Piersma-Wichers, M., Van Gelder, I. C., Rienstra, M., Tieleman, R. G. Tags: Atrial fibrillation Source Type: research

Antithrombotic therapy use in patients with atrial fibrillation before the era of non-vitamin K antagonist oral anticoagulants: the Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF) Phase I cohort
Conclusion Phase I of GLORIA-AF shows that VKAs were mostly used in patients with persistent/permanent (vs. paroxysmal) AF and in those with high stroke risk. Furthermore, there were meaningful geographical differences in the use of VKA therapy in the era before the availability of NOACs, including a much lower use of VKAs in China, where most patients either received antiplatelet agents or no antithrombotic treatment. (Source: Europace)
Source: Europace - August 30, 2016 Category: Cardiology Authors: Huisman, M. V., Ma, C. S., Diener, H.-C., Dubner, S. J., Halperin, J. L., Rothman, K. J., Teutsch, C., Schoof, N., Kleine, E., Bartels, D. B., Lip, G. Y. H., for the GLORIA-AF Investigators Tags: Atrial fibrillation Source Type: research

Extra-cardiac stimulators: what do cardiologists need to know?
For several decades, treating patients with pacemakers has been the privilege of cardiologists. However, in the last 30 years, researchers have found new targets for electrical stimulation in different clinical subspecialities, such as deep brain stimulation (for the treatment of Parkinson's disease, essential tremor, dystonia, and some psychiatric illnesses); spinal cord stimulation (for refractory angina, chronic pain, and peripheral artery disease); and sacral (for diverse urologic and proctologic conditions), vagal (for epilepsy), and phrenic nerve stimulation (for sleep apnoea). The purpose of this article is to famil...
Source: Europace - August 30, 2016 Category: Cardiology Authors: Guinand, A., Noble, S., Frei, A., Renard, J., Tramer, M. R., Burri, H. Tags: REVIEWS Source Type: research

Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop
Both biomedical research and clinical practice rely on complex datasets for the physiological and genetic characterization of human hearts in health and disease. Given the complexity and variety of approaches and recordings, there is now growing recognition of the need to embed computational methods in cardiovascular medicine and science for analysis, integration and prediction. This paper describes a Workshop on Computational Cardiovascular Science that created an international, interdisciplinary and inter-sectorial forum to define the next steps for a human-based approach to disease supported by computational methodologi...
Source: Europace - August 30, 2016 Category: Cardiology Authors: Rodriguez, B., Carusi, A., Abi-Gerges, N., Ariga, R., Britton, O., Bub, G., Bueno-Orovio, A., Burton, R. A. B., Carapella, V., Cardone-Noott, L., Daniels, M. J., Davies, M. R., Dutta, S., Ghetti, A., Grau, V., Harmer, S., Kopljar, I., Lambiase, P., Lu, H. Tags: REVIEWS Source Type: research

Longevity of implantable cardioverter-defibrillators: still a long way to go
(Source: Europace)
Source: Europace - August 30, 2016 Category: Cardiology Authors: Johansen, J. B., Nielsen, J. C., Sandgaard, N. C. F. Tags: EDITORIALS Source Type: research

Pharmacoepidemiological comparisons between acenocoumarol and dabigatran: interpretation of data reflecting clinical practice
(Source: Europace)
Source: Europace - August 30, 2016 Category: Cardiology Authors: Nielsen, P. B. Tags: EDITORIALS Source Type: research

Incidence of asymptomatic oesophageal lesions after atrial fibrillation ablation using an oesophageal temperature probe with insulated thermocouples: a comparative controlled study
ConclusionAccording to these preliminary results, the use of oesophageal temperature probes with insulated thermocouples seems to be feasible in patients undergoing AF RF catheter ablation. The incidence of post-procedural EDEL when using a cut-off of 39°C is comparable to the incidence of EDEL without using a temperature probe. (Source: Europace)
Source: Europace - August 17, 2016 Category: Cardiology Source Type: research

Percutaneous left atrial appendage occlusion: the Munich consensus document on definitions, endpoints, and data collection requirements for clinical studies
The increasing interest in left atrial appendage occlusion (LAAO) for ischaemic stroke prevention in atrial fibrillation (AF) fuels the need for more clinical data on the safety and effectiveness of this therapy. Besides an assessment of the effectiveness of the therapy in specific patients groups, comparisons with pharmacological stroke prophylaxis, surgical approaches, and other device-based therapies are warranted. This paper documents the consensus reached among clinical experts in relevant disciplines from Europe and North America, European cardiology professional societies, and representatives from the medical device...
Source: Europace - August 17, 2016 Category: Cardiology Source Type: research

Assessing cardiac autonomic function via heart rate variability analysis requires monitoring respiration: reply
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Malik, M., Sassi, R., Cerutti, S., Lombardi, F., Huikuri, H. V., Peng, C.-K., Schmidt, G., Yamamoto, Y. Tags: LETTERS TO THE EDITOR Source Type: research

Assessing cardiac autonomic function via heart rate variability analysis requires monitoring respiration
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Wessel, N., Sidorenko, L., Kraemer, J. F., Schoebel, C., Baumann, G. Tags: LETTERS TO THE EDITOR Source Type: research

Combining an subcutaneous ICD and a pacemaker with abdominal device location and bipolar epicardial left ventricular lead: first-in-man approach
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Gemein, C., Haj, M., Schmitt, J. Tags: CASE EXPRESS REPORTS Source Type: research

Diagnostic role of head-up tilt test in patients with cough syncope
Conclusion Syncope during coughing is a result of hypotension, rather than bradycardia. Coughing during HUT is a useful test in patients suspected to have cough syncope but in whom the history is not conclusive. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Mereu, R., Taraborrelli, P., Sau, A., Di Toro, A., Halim, S., Hayat, S., Bernardi, L., Francis, D. P., Sutton, R., Lim, P. B. Tags: Syncope and event loop recorders Source Type: research

External prolonged electrocardiogram monitoring in unexplained syncope and palpitations: results of the SYNARR-Flash study
Aims SYNARR-Flash study (Monitoring of SYNcopes and/or sustained palpitations of suspected ARRhythmic origin) is an international, multicentre, observational, prospective trial designed to evaluate the role of external 4-week electrocardiogram (ECG) monitoring in clinical work-up of unexplained syncope and/or sustained palpitations of suspected arrhythmic origin. Methods and results Consecutive patients were enrolled within 1 month after unexplained syncope or palpitations (index event) after being discharged from emergency room or hospitalization without a conclusive diagnosis. A 4-week ECG monitoring was obtained by ext...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Locati, E. T., Moya, A., Oliveira, M., Tanner, H., Willems, R., Lunati, M., Brignole, M. Tags: Syncope and event loop recorders Source Type: research

Novel electrophysiological characteristics of atrioventricular nodal continuous conduction curves in atrioventricular nodal re-entrant tachycardia with concomitant cavotricuspid isthmus-dependent atrial flutter
Conclusion Atrioventricular nodal re-entrant tachycardia patients with concomitant CTI-dependent AFL had more continuous AV node function curves. Forty-one per cent of these patients had non-inducible AFL after the SP ablation, indicating a slow conduction isthmus in the triangle of Koch area. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Lin, C.-H., Lin, Y.-J., Chang, S.-L., Lo, L.-W., Huang, H.-K., Chiang, C.-H., Allamsetty, S., Liao, J.-N., Chung, F.-P., Chang, Y.-T., Lin, C.-Y., Chen, S.-A. Tags: Cardiac electrophysiology Source Type: research

Early repolarization pattern and its day-to-day dynamic change as markers for ventricular fibrillation in patients with vasospastic angina
This study aimed to clarify the relation between ER and VF in patients with VSA and to investigate the long-term outcomes of ICD therapy. Methods and results This retrospective, observational survey evaluated 265 consecutive VSA patients, including 21 with VF. Their electrocardiogram findings and clinical course were analysed over a mean follow-up of 5.5 ± 3.3 years. Early repolarization was observed in 64 patients (24.2%) and was more frequent in patients with VF history than those without (P = 0.001). Early repolarization was independently associated with VF history. During follow-up, four patients had VF recurre...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Kitamura, T., Fukamizu, S., Hojo, R., Aoyama, Y., Komiyama, K., Nishizaki, M., Sakurada, H., Hiraoka, M. Tags: Cardiac electrophysiology Source Type: research

The limbus of the fossa ovalis: an unusual location for incessant focal atrial tachycardia in children
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Di Pino, A., Caruso, E., Gitto, P. Tags: CASE EXPRESS REPORTS Source Type: research

Propofol sedation administered by cardiologists for patients undergoing catheter ablation for ventricular tachycardia
Aims Propofol sedation has been shown to be safe for atrial fibrillation ablation and internal cardioverter-defibrillator implantation but its use for catheter ablation (CA) of ventricular tachycardia (VT) has yet to be evaluated. Here, we tested the hypothesis that VT ablation can be performed using propofol sedation administered by trained nurses under a cardiologist's supervision. Methods and results Data of 205 procedures (157 patients, 1.3 procedures/patient) undergoing CA for sustained VT under propofol sedation were analysed. The primary endpoint was change of sedation and/or discontinuation of propofol sedation du...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Servatius, H., Höfeler, T., Hoffmann, B. A., Sultan, A., Lüker, J., Schäffer, B., Willems, S., Steven, D. Tags: Cardiac electrophysiology Source Type: research

Solvent-facilitated lead disconnection for battery replacement in patients with pacemakers or implantable cardioverter defibrillators
Conclusion Ethanol has utility as a simple and inexpensive modality for lead disconnection from ICD or PM headers. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Erne, P., Kobza, R., Lehner, M., Resink, T. J. Tags: Leads and lead extraction Source Type: research

Inappropriate high-rate pacing with maximal output due to runaway pacemaker malfunction in a temporary device
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Park, S. M., Son, J.-W., Hong, K.-S. Tags: CASE EXPRESS REPORTS Source Type: research

Active fixation of a thin transvenous left-ventricular lead by a side helix facilitates targeted and stable placement in cardiac resynchronization therapy
Conclusion Active fixation of this 4Fr LV lead by using a side helix, offers flexibility to place the lead precisely in targeted vein segments over a wide range of vein anatomies. The average LV pacing threshold was low at implantation and follow-ups. The lead seems to be extractable and no late dislodgements have been observed. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Keilegavlen, H., Hovstad, T., Faerestrand, S. Tags: Leads and lead extraction Source Type: research

Haemodynamic effects of cardiac resynchronization therapy using single-vein, three-pole, multipoint left ventricular pacing in patients with ischaemic cardiomyopathy and a left ventricular free wall scar: the MAESTRO study
Aims The clinical response to cardiac resynchronization therapy (CRT) is variable. Multipoint left ventricular (LV) pacing could achieve more effective haemodynamic response than single-point LV pacing. Deployment of an LV lead over myocardial scar is associated with a poor haemodynamic response to and clinical outcome of CRT. We sought to determine whether the acute haemodynamic response to CRT using three-pole LV multipoint pacing (CRT3P-MPP) is superior to that to conventional CRT using single-site LV pacing (CRTSP) in patients with ischaemic cardiomyopathy and an LV free wall scar. Methods and results Sixteen patients...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Umar, F., Taylor, R. J., Stegemann, B., Marshall, H., Flannigan, S., Lencioni, M., De Bono, J., Griffith, M., Leyva, F. Tags: Pacing and resynchronization therapy Source Type: research

Prevalence and predictor factors of severe venous obstruction after cardiovascular electronic device implantation
Conclusion In patients with implantable devices, severe venous obstruction prevalence is not negligible and the lack of symptoms does not exclude it. The presence of three leads and sudden cardiac death as indication for implantable devices seem to be associated with the presence of severe venous obstruction/occlusion. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Santini, M., Di Fusco, S. A., Santini, A., Magris, B., Pignalberi, C., Aquilani, S., Colivicchi, F., Gargaro, A., Ricci, R. P. Tags: Pacing and resynchronization therapy Source Type: research

Atrial reverse remodelling is associated with outcome of cardiac resynchronization therapy
Conclusion Patients without atrial and ventricular reverse remodelling have the worst outcome. Patients with only atrial reverse remodelling have improved left ventricular diastolic filling during follow-up and demonstrate a comparable outcome with patients with both atrial and ventricular reverse remodelling. Assessment of atrial reverse remodelling may provide additional prognostic information in determining CRT outcome. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Kloosterman, M., Rienstra, M., Mulder, B. A., Van Gelder, I. C., Maass, A. H. Tags: Pacing and resynchronization therapy Source Type: research

Primary prevention implantable cardioverter-defibrillator and cardiac resynchronization therapy-defibrillator in elderly patients: results of a Spanish multicentre study
Aims Currently, there continues to be a lack of evidence regarding outcomes associated with device-based therapy for ventricular arrhythmias in elderly patients, even more in primary-prevention indications. We aimed to describe the follow-up in terms of efficacy and safety of implantable cardioverter-defibrillator (ICD) therapy in a large cohort of elderly patients. Methods and results Retrospective multicentre study performed in 15 Spanish hospitals. Consecutive patients referred for ICD implantation before 2011 were included. One hundred and sixty-two of 1174 patients (13.8%) ≥75 years were considered as ‘elder...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Exposito, V., Rodriguez-Manero, M., Gonzalez-Enriquez, S., Arias, M. A., Sanchez-Gomez, J. M., Andres La Huerta, A., Bertomeu-Gonzalez, V., Arce-Leon, A., Barrio-Lopez, M. T., Arguedas-Jimenez, H., Seara, J. G., Rodriguez-Entem, F. Tags: Sudden death and ICDs Source Type: research

Retrieval of Medtronic Micra Transcatheter Pacing System after tether removal
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Gerdes, C., Nielsen, J. C. Tags: CASE EXPRESS REPORTS Source Type: research

Sex difference in appropriate shocks but not mortality during long-term follow-up in patients with implantable cardioverter-defibrillators
Aims Implantable cardioverter-defibrillators (ICDs) have been shown to improve survival, although a considerable number of patients never receive therapy. Implantable cardioverter-defibrillators are routinely implanted regardless of sex. There is continuing controversy whether major outcomes differ between men and women. Methods and results In this retrospective single-centre study, 1151 consecutive patients (19% women) undergoing ICD implantation between 1998 and 2010 were followed for mortality and first appropriate ICD shock over 4.9 ± 2.7 years. Sex-related differences were investigated using multivariable Cox ...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Seegers, J., Conen, D., Jung, K., Bergau, L., Dorenkamp, M., Lüthje, L., Sohns, C., Sossalla, S. T., Fischer, T. H., Hasenfuss, G., Friede, T., Zabel, M. Tags: Sudden death and ICDs Source Type: research

Applicability of a risk score for prediction of the long-term benefit of the implantable cardioverter defibrillator in patients receiving cardiac resynchronization therapy
Conclusion A simple risk stratification score comprising five clinical risk factors may help identify CRT patients who are more likely to benefit from the presence of the defibrillator. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Barra, S., Looi, K.-L., Gajendragadkar, P. R., Khan, F. Z., Virdee, M., Agarwal, S. Tags: Sudden death and ICDs Source Type: research

Entrapment of a diagnostic catheter in a novel multipolar basket catheter (Orion™) during right atrial mapping
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Knecht, S., Novak, J., Kühne, M. Tags: CASE EXPRESS REPORTS Source Type: research

Fluoroscopic position of the second-generation cryoballoon during ablation in the right superior pulmonary vein as a predictor of phrenic nerve injury
Aims Phrenic nerve injury (PNI) is the most frequently observed complication during pulmonary vein isolation procedure using the second-generation cryoballoon (CB). Our objective was to analyse the correlation between the fluoroscopic position of the 28 mm CB during ablation in the right superior pulmonary vein (RSPV) and the occurrence of PNI. Methods and results A total of 165 patients having undergone the large 28 mm CB ablation were retrospectively reviewed. Positioning of the CB relative to the cardiac silhouette was classified under fluoroscopic guidance in antero-posterior projection during RSPV ablation. Regarding...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Saitoh, Y., Ströker, E., Irfan, G., Mugnai, G., Ciconte, G., Hünük, B., Velagic, V., Overeinder, I., Tanaka, K., Brugada, P., de Asmundis, C., Chierchia, G.-B. Tags: Ablation for atrial fibrillation Source Type: research

One-year clinical outcome after ablation with a novel multipolar irrigated ablation catheter for treatment of atrial fibrillation: potential implications for clinical use
Aims Pulmonary vein isolation (PVI) is an established therapy for atrial fibrillation (AF). However, PVI remains a time-consuming procedure. A novel multipolar irrigated radiofrequency (RF) ablation catheter (nMARQ™) is aiming to improve PVI. We investigated the influence on procedural parameters and assessed clinical outcomes after PVI using this novel catheter. Methods and results Fifty-eight consecutive patients with paroxysmal AF were equally allocated (n = 29/group) to PVI treatment with (i) the novel multipolar ablation catheter (nMARQ™) and (ii) a standard single-tip ablation catheter (SAC). Study endpo...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Wakili, R., Siebermair, J., Fichtner, S., Sinner, M. F., Klocker, E., Olesch, L., Hilberath, J. N., Sarai, S., Clauss, S., Sattler, S., Kääb, S., Estner, H. L. Tags: Ablation for atrial fibrillation Source Type: research

Safety and efficacy of the nMARQ catheter for paroxysmal and persistent atrial fibrillation
Conclusion The nMARQ catheter is a highly effective tool for treatment of paroxysmal and persistent AF. Nevertheless, the occurrence of life-threatening oesophageal fistulas is of major concern and requires further investigation. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Vurma, M., Dang, L., Brunner-La Rocca, H.-P., Sütsch, G., Attenhofer-Jost, C. H., Duru, F., Scharf, C. Tags: Ablation for atrial fibrillation Source Type: research

Incidence of real-time recordings of pulmonary vein potentials using the third-generation short-tip cryoballoon
Conclusion The rate of visualization of RT recordings is significantly high during third-generation CB-ST ablation. Real-time recordings can be visualized in ~87.1% of veins with this novel cryoballoon. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Chierchia, G.-B., Mugnai, G., Ströker, E., Velagic, V., Hünük, B., Moran, D., Hacioglu, E., Poelaert, J., Verborgh, C., Umbrain, V., Beckers, S., Ruggiero, D., Brugada, P., de Asmundis, C. Tags: Ablation for atrial fibrillation Source Type: research

Real-world persistence and adherence to oral anticoagulation for stroke risk reduction in patients with atrial fibrillation
Aim To assess persistence and adherence to rivaroxaban, dabigatran, and vitamin K antagonist (VKA) treatment in primary care patients with non-valvular atrial fibrillation (AF) newly starting anticoagulant therapy. Methods and results Prescription data for oral anticoagulants were obtained from 7265 eligible patients from primary care practices across Germany. Persistence with and adherence to anticoagulation were assessed in anticoagulant-naïve patients with AF newly treated with dabigatran, rivaroxaban, or VKA during follow-up periods of at least 180 days, respectively 360 days after the prescription date. Persistence...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Beyer-Westendorf, J., Ehlken, B., Evers, T. Tags: Atrial fibrillation Source Type: research

Serum 25-hydroxyvitamin D and the incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study
Conclusion Low serum 25(OH)D was not associated with incident AF in a community-based cohort and in a meta-analysis of prospective studies. A possible association in younger individuals warrants further investigation. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Alonso, A., Misialek, J. R., Michos, E. D., Eckfeldt, J., Selvin, E., Soliman, E. Z., Chen, L. Y., Gross, M. D., Lutsey, P. L. Tags: Atrial fibrillation Source Type: research

Hospitalizations in patients with atrial fibrillation: an analysis from ROCKET AF
We described the frequency of and reasons for hospitalization during study follow-up and utilized Cox proportional hazards models to assess for baseline characteristics associated with all-cause hospitalization. Of 14 171 patients, 14% were hospitalized at least once. Of 2614 total hospitalizations, 41% were cardiovascular including 4% for AF; of the remaining, 12% were for bleeding. Compared with patients not hospitalized, hospitalized patients were older (74 vs. 72 years), and more frequently had diabetes (46 vs. 39%), prior MI (23 vs. 16%), and paroxysmal AF (19 vs. 17%), but less frequently had prior transient ischaemi...
Source: Europace - August 4, 2016 Category: Cardiology Authors: DeVore, A. D., Hellkamp, A. S., Becker, R. C., Berkowitz, S. D., Breithardt, G., Hacke, W., Halperin, J. L., Hankey, G. J., Mahaffey, K. W., Nessel, C. C., Singer, D. E., Fox, K. A. A., Patel, M. R., Piccini, J. P., on behalf of the ROCKET AF Steering Com Tags: Atrial fibrillation Source Type: research

Current and future developments in the field of central sleep apnoea
Central sleep apnoea (CSA) occurs in ~30–50% of patients with heart failure (HF) with reduced left ventricular ejection fraction (LVEF) and in as much as in 18–30% of patients with preserved LVEF. In HF patients, it is characterized by periodic breathing also known as the Cheyne–Stokes respiration followed by pauses of breathing. Central sleep apnoea remains often unrecognized due to its chronic and insidious incidences. Patients may report excessive daytime somnolence, poor sleep quality, nocturnal angina, recurrent arrhythmias, refractory HF symptoms, or demonstrate abnormal respiratory pattern or apnoe...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Bekfani, T., Abraham, W. T. Tags: REVIEW Source Type: research

Catheter ablation for atrial fibrillation in congestive heart failure: consider the upside, consider the downside
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Wong, G. R., Kalman, J. M. Tags: EDITORIALS Source Type: research

Last call on nMARQ™ safety
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Dekker, L. R. Tags: EDITORIALS Source Type: research

Challenges in atrial fibrillation beyond stroke prevention: keeping patients out of the hospital
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Pokorney, S. D., Steinberg, B. A. Tags: EDITORIALS Source Type: research

Do we need intracardiac echo to guide ablation of ventricular arrhythmias from the papillary muscles?
This editorial refers to ‘Intracardiac echo-facilitated 3D electroanatomical mapping of ventricular arrhythmias from the papillary muscles: assessing the “fourth dimension” during ablation’ by R. Proiettiet al., on pages21 –28. (Source: Europace)
Source: Europace - August 2, 2016 Category: Cardiology Source Type: research

Intracardiac echo-facilitated 3D electroanatomical mapping of ventricular arrhythmias from the papillary muscles: assessing the ‘fourth dimension’ during ablation
ConclusionAn echo-facilitated 3D electroanatomical mapping allows for real-time creation of precise geometries of cardiac chambers and endocavitary structures. This is useful during procedures such as catheter ablation of VAs originating from PMs, which require detailed representation of anatomical landmarks. Routine adoption of this technique should be considered to improve outcomes of PM VA ablation. (Source: Europace)
Source: Europace - August 1, 2016 Category: Cardiology Source Type: research

Cardiac resynchronization therapy: mechanisms of action and scope for further improvement in cardiac function
AbstractAimsCardiac resynchronization therapy (CRT) may exert its beneficial haemodynamic effect by improving ventricular synchrony and improving atrioventricular (AV) timing. The aim of this study was to establish the relative importance of the mechanisms through which CRT improves cardiac function and explore the potential for additional improvements with improved ventricular resynchronization.Methods and ResultsWe performed simulations using the CircAdapt haemodynamic model and performed haemodynamic measurements while adjusting AV delay, at low and high heart rates, in 87 patients with CRT devices. We assessed QRS dura...
Source: Europace - July 13, 2016 Category: Cardiology Source Type: research

J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge
Sudden cardiac deathJ waveBrugada syndromeEarly repolarization syndromeCardiac arrhythmiaVentricular fibrillationInherited cardiac arrhythmia syndrome (Source: Europace)
Source: Europace - July 13, 2016 Category: Cardiology Source Type: research

Strategies for prediction and early detection of atrial fibrillation: present and future
This editorial refers to ‘CHA2DS2-VASc score and blood biomarkers to identify patients with atrial high-rate episodes and paroxysmal atrial fibrillation’ by P. Wakulaet al., on pages 544 –551. (Source: Europace)
Source: Europace - July 7, 2016 Category: Cardiology Source Type: research

Association of pre-ablation level of potential blood markers with atrial fibrillation recurrence after catheter ablation: a meta-analysis
ConclusionIncreased pre-ablation level of ANP, BNP, NT-pro-BNP, IL-6, C-reactive protein, LDL, and TIMP-2 was associated with greater risk of AF recurrence after RFCA. (Source: Europace)
Source: Europace - July 6, 2016 Category: Cardiology Source Type: research