Reduction of radiation exposure in cryoballoon ablation procedures: a single-centre study applying intracardiac echocardiography and other radioprotective measures
AbstractAimsThe population treated with cryoballoon (CB) ablation is relatively young, and radiation protection is of major importance. We aimed to demonstrate that radiation exposure can be markedly reduced by intracardiac echocardiography (ICE) and optimized settings of the X-ray system.Methods and resultsWe analysed 100 patients undergoing CB pulmonary vein isolation (PVI) for treatment of paroxysmal atrial fibrillation. In 50 consecutive patients (25 male, 59 ± 13 years; Group 1), we used ICE, skipped PV angiography prior to CB inflation, and avoided fluoroscopy whenever possible. Furthermore, we reduced the fra...
Source: Europace - June 2, 2016 Category: Cardiology Source Type: research

Exome sequencing in arrhythmogenic right ventricular cardiomyopathy: a new diagnostic tool?
This editorial refers to ‘Arrhythmogenic right ventricular cardiomyopathy: implications of next-generation sequencing in appropriate diagnosis, by A. Medeiros-Domingoet al., on pages 1063 –1069. (Source: Europace)
Source: Europace - June 2, 2016 Category: Cardiology Source Type: research

Magnetic resonance imaging in patients with cardiac implanted electronic devices: focus on contraindications to magnetic resonance imaging protocols
ConclusionUsing a pre-specified protocol, cardiac and non-cardiac MRIs were performed in CIED patients with pacemaker dependency, abandoned leads, or depleted batteries without occurrence of major adverse events. Patients with devices on advisory need to be monitored carefully during MRI, especially if they are pacemaker dependent. (Source: Europace)
Source: Europace - June 2, 2016 Category: Cardiology Source Type: research

Influence of patients' age at implantation on mortality and defibrillator shocks
AimsPatients have increasing comorbidities and competing causes of death with advancing age, raising questions about the effectiveness of the implantable cardioverter defibrillators (ICD) in older age. We therefore investigated the effect of patients' age at initial device implantation on all-cause mortality and on the risk of ICD shocks in single-chamber (V-ICD), dual-chamber (D-ICD), and cardiac resynchronization therapy defibrillator (CRT-D) recipients.Methods and resultsWe reviewed de-identified records of 67 128 ICD recipients enrolled in the Boston Scientific ALTITUDE database of remote monitored patients [V-ICD (n =...
Source: Europace - June 2, 2016 Category: Cardiology Source Type: research

Implanted defibrillators in trouble: initial device misclassification leads to correct diagnosis —a case series
ConclusionThorough analysis of stored electrograms yielded correct diagnosis in all cases, which subsequently was confirmed by electrophysiological study. (Source: Europace)
Source: Europace - June 2, 2016 Category: Cardiology Source Type: research

Limited left atrial surgical ablation effectively treats atrial fibrillation but decreases left atrial function
AimsLimited left atrial (LA) surgical ablation with bipolar radiofrequency is considered to be an effective procedure for treatment of atrial fibrillation (AF). We studied whether limited LA surgical ablation concomitant to cardiac surgery is able to maintain LA function.Methods and ResultsThirty-six consecutive patients (age 66 ± 12 years, 53% male, 78% persistent AF) scheduled for valve surgery and/or coronary revascularization and concomitant LA surgical ablation were included. Epicardial pulmonary vein isolation (PVI) and additional endo-epicardial lines were performed using bipolar radiofrequency. An age- and g...
Source: Europace - June 2, 2016 Category: Cardiology Source Type: research

Self-reported physical activity and major adverse events in patients with atrial fibrillation: a report from the EURObservational Research Programme Pilot Survey on Atrial Fibrillation (EORP-AF) General Registry
AimsPhysical activity is protective against cardiovascular (CV) events, both in general population and in high-risk CV cohorts. However, the relationship between physical activity with major adverse outcomes in atrial fibrillation (AF) is not well-established. Our aim was to analyse this relationship in a ‘real-world’ AF population. Second, we investigated the influence of physical activity on arrhythmia progression.Methods and ResultsWe studied all patients enrolled in the EURObservational Research Programme on AF (EORP-AF) Pilot Survey. Physical activity was defined as ‘none’, ‘occasional&rs...
Source: Europace - June 2, 2016 Category: Cardiology Source Type: research

Provision of magnetic resonance imaging for patients with ‘MR-conditional’ cardiac implantable electronic devices: an unmet clinical need
ConclusionProvision of MRI for patients with CIEDs is currently poor, despite increasing numbers of patients with MR-conditional devices and extremely low reported complication rates. (Source: Europace)
Source: Europace - June 1, 2016 Category: Cardiology Source Type: research

Atypical lower loop reentrant tachycardia associated with multiple hepatic veins
(Source: Europace)
Source: Europace - June 1, 2016 Category: Cardiology Source Type: research

Premature termination of radiofrequency delivery during pulmonary vein isolation due to oesophageal temperature alerts: impact on acute and chronic pulmonary vein reconnection
ConclusionJust over half of patients undergoing PV isolation will have an oesophageal temperature alert, however, precautionary oesophageal temperature monitoring does not compromise ablation efficacy. (Source: Europace)
Source: Europace - May 31, 2016 Category: Cardiology Source Type: research

Is modification of the VVI backup mode in implantable cardioverter-defibrillators from St Jude medical required due to increased risk of inappropriate shocks?
Inappropriate implantable cardioverter-defibrillator (ICD) shock therapy is painful, stressful, and typically occurs unexpected in conscious patients and may be related to a less favourable prognosis. In our institution, we have observed four cases of multiple inappropriate ICD shocks during reset to VVI backup mode. All four patients were implanted with a St Jude Medical ICD since 2010. The reset to VVI backup mode happens as a ‘safety’ response when the ICD encounters errors in the software or hardware often due to electromagnetic interference. The ICD then operates in a simple mode, with only a ventricular f...
Source: Europace - May 31, 2016 Category: Cardiology Source Type: research

Ablation index, a novel marker of ablation lesion quality: prediction of pulmonary vein reconnection at repeat electrophysiology study and regional differences in target values
AimsForce –Time Integral (FTI) is commonly used as a marker of ablation lesion quality during pulmonary vein isolation (PVI), but does not incorporate power. Ablation Index (AI) is a novel lesion quality marker that utilizes contact force, time, and power in a weighted formula. Furthermore, only a single FT I target value has been suggested despite regional variation in left atrial wall thickness. We aimed to study AI's and FTI's relationships with PV reconnection at repeat electrophysiology study, and regional threshold values that predicted no reconnection.Methods and resultsForty paroxysmal atrial fibrillation pat...
Source: Europace - May 31, 2016 Category: Cardiology Source Type: research

Left ventricular dysfunction is associated with frequent premature ventricular complexes and asymptomatic ventricular tachycardia in children
ConclusionIn children with idiopathic PVCs and asymptomatic VTs, development of LV dysfunction is associated with a higher burden of PVCs, the presence of sVTs, and couplets. Left ventricular dysfunction appears to be reversible if the burden of PVCs is decreased by medication or ablation. (Source: Europace)
Source: Europace - May 31, 2016 Category: Cardiology Source Type: research

Long-term outcome of transvenous pacemaker implantation in infants: a retrospective cohort study
AimEvaluation of long-term outcome of transvenous pacemaker (PM) implantation in infants.Methods and ResultsA retrospective analysis of all transvenous PM implantations in infants
Source: Europace - May 31, 2016 Category: Cardiology Source Type: research

Impact of basal inferolateral scar burden determined by automatic analysis of 99m Tc-MIBI myocardial perfusion SPECT on the long-term prognosis of cardiac resynchronization therapy
ConclusionThe scarring determined by automatic analysis of MP-SPECT images may predict a poor response to CRT regardless of the pathogenesis of cardiomyopathy. The basal inferolateral scar burden in particular may have an adverse impact on long-term prognosis. (Source: Europace)
Source: Europace - May 31, 2016 Category: Cardiology Source Type: research

Geometry of Koch's triangle
ConclusionMean values and proportions of triangle's sides and angles were presented. Koch's triangle showed considerable individual variations in size. The dimensions of the triangle were strongly independent from individual-specific and heart-specific morphometric parameters; however, the maximum triangle's height can be estimated as 22 mm. (Source: Europace)
Source: Europace - May 30, 2016 Category: Cardiology Source Type: research

Sudden cardiac death in adult congenital heart disease: can the unpredictable be foreseen?
AimsSudden cardiac death (SCD) is a major cause of mortality in adults with congenital heart disease (CHD). Several risk factors for SCD including conduction disturbances and ventricular dysfunction have been described previously. However, electrocardiogram (ECG) and echocardiographic parameters may change over time, and the predictive value of such temporal changes, rather than their point estimates, for SCD remains unknown.Methods and resultsThis was a retrospective case–control study in adults with CHD and proven or presumed SCD and matched controls. Data were obtained from three databases including 25 000 adults ...
Source: Europace - May 30, 2016 Category: Cardiology Source Type: research

Atrial fibrillation and gastroesophageal reflux disease: the cardiogastric interaction
Atrial fibrillation (AF) is the most common sustained arrhythmia and is associated with significant morbidity and mortality. Multiple conditions like hypertension, heart failure, diabetes, sleep apnoea, and obesity play a role for the initiation and perpetuation of AF. Recently, a potential association between gastroesophageal reflux disease (GERD) and AF development has been proposed due to the close anatomic vicinity of the oesophagus and the left atrium. As an understanding of the association between acid reflux disease and AF may be important in the global multimodal treatment strategy to further improve outcomes in a ...
Source: Europace - May 30, 2016 Category: Cardiology Source Type: research

Midterm clinical outcomes of concomitant thoracoscopic epicardial and transcatheter endocardial ablation for persistent and long-standing persistent atrial fibrillation: a single-centre experience
ConclusionThe hybrid procedure yields promising results in the setting of both persistent and long-standing persistent AF after midterm follow-up, at the expense of a non-negligible rate of adverse events. Our findings need to be confirmed by further larger and prospective studies. (Source: Europace)
Source: Europace - May 30, 2016 Category: Cardiology Source Type: research

Influence of automatic frequent pace-timing adjustments on effective left ventricular pacing during cardiac resynchronization therapy
ConclusionAdaptivCRT ™ significantly increased effective LV pacing over echo-optimized CRT. (Source: Europace)
Source: Europace - May 26, 2016 Category: Cardiology Source Type: research

Long-term follow-up of implantable cardioverter-defibrillators in adult congenital heart disease patients: indications and outcomes
ConclusionsMost patients had ICD for secondary prevention (62%), and the majority had repaired TOF. There was a 2.9% annual appropriate shock rate. However, there was a high incidence of complications with more than a third suffering a major complication (9% per annum). The risks and benefits of ICD implantation are patient and disease specific, and must be clearly discussed prior to implantation. Further research is warranted into the use of primary prevention ICD in ACHD and in alternatives to ICD such as ablation in specific patient groups. (Source: Europace)
Source: Europace - May 25, 2016 Category: Cardiology Source Type: research

Programmed ventricular stimulation early after myocardial infarction: authors' reply
(Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Spaulding, C., Blomstrom Lundqvist,, C., Priori, S. G. Tags: LETTERS TO THE EDITOR Source Type: research

Programmed ventricular stimulation early after myocardial infarction: are the guidelines right?
(Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Kulakowski, P. Tags: LETTERS TO THE EDITOR Source Type: research

Stakeholders in NOACs prescription: authors' reply
(Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Andreotti, F., Pinto, F. J., Camm, A. J., on behalf of the Action for Stroke Prevention Alliance Tags: LETTERS TO THE EDITOR Source Type: research

Stakeholders in non-Vitamin K antagonist oral anticoagulants prescription: the case of Italy
(Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: De Sensi, F., Paneni, F. Tags: LETTERS TO THE EDITOR Source Type: research

European Heart Rhythm Association Young Electrophysiology Community: the future is just ahead
(Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Kutyifa, V., Arbelo, E., Barsamyan, S., Kosiuk, J., Metzner, A., Pazdernik, M., De Potter, T. Tags: YOUNG EP Source Type: research

Perioperative management of antithrombotic treatment during implantation or revision of cardiac implantable electronic devices: the European Snapshot Survey on Procedural Routines for Electronic Device Implantation (ESS-PREDI)
The European Snapshot Survey on Procedural Routines for Electronic Device Implantation (ESS-PREDI) was a prospective European survey of consecutive adults who had undergone implantation/surgical revision of a cardiac implantable electronic device (CIED) on chronic antithrombotic therapy (enrolment March–June 2015). The aim of the survey was to investigate perioperative treatment with oral anticoagulants and antiplatelets in CIED implantation or surgical revision and to determine the incidence of complications, including clinically significant pocket haematomas. Information on antithrombotic therapy before and after s...
Source: Europace - May 24, 2016 Category: Cardiology Authors: Deharo, J.-C., Sciaraffia, E., Leclercq, C., Amara, W., Doering, M., Bongiorni, M. G., Chen, J., Dagres, N., Estner, H., Larsen, T. B., Johansen, J. B., Potpara, T. S., Proclemer, A., Pison, L., Brunet, C., Blomström-Lundqvist, C., Coordinated by Tags: EHRA SURVEY Source Type: research

Comparison of the new risk prediction model (HCM Risk-SCD) and classic risk factors for sudden death in patients with hypertrophic cardiomyopathy and defibrillator
Aims Hypertrophic cardiomyopathy is one of the main causes of sudden death in young people. Recent clinical practice guidelines include a risk prediction model for sudden death (HCM Risk-SCD), which facilitates the decision of whether to implant a defibrillator. The aim of our study was to ascertain the percentage of events in our series of primary prevention implantable cardioverter-defibrillator recipients with hypertrophic cardiomyopathy and whether HCM Risk-SCD predicts the onset of arrhythmic events. Methods and results This was an observational, retrospective cohort study, which included 48 primary prevention defibr...
Source: Europace - May 24, 2016 Category: Cardiology Authors: Ruiz-Salas, A., Garcia-Pinilla, J. M., Cabrera-Bueno, F., Fernandez-Pastor, J., Pena-Hernandez, J., Medina-Palomo, C., Barrera-Cordero, A., De Teresa, E., Alzueta, J. Tags: Electrocardiology and risk stratification Source Type: research

Interrelationship between electrocardiographic left ventricular hypertrophy, QT prolongation, and ischaemic stroke: the REasons for Geographic and Racial Differences in Stroke Study
Conclusion The combination of ECG-LVH and prolonged QT is associated with a higher risk of ischaemic stroke compared with either condition in isolation, and the stroke risk for each condition does not depend on the presence of the other. (Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: O'Neal, W. T., Howard, V. J., Kleindorfer, D., Kissela, B., Judd, S. E., McClure, L. A., Cushman, M., Howard, G., Soliman, E. Z. Tags: Electrocardiology and risk stratification Source Type: research

Lead extractions: the Zwolle experience with the Evolution mechanical sheath
Conclusion Use of Evolution for lead extractions seems to be safe and effective, with a high clinical success rate. (Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Delnoy, P. P. H. M., Witte, O. A., Adiyaman, A., Ghani, A., Smit, J. J. J., Ramdat Misier, A. R., Elvan, A. Tags: Leads and lead extraction Source Type: research

First clinical evaluation of an atrial haemodynamic sensor lead for automatic optimization of cardiac resynchronization therapy
Conclusion The atrial lead is safe to implant and shows stable electrical performance over time. It therefore offers a promising tool for automatic CRT optimization to further improve responder rates to CRT. (Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Duncker, D., Delnoy, P. P., Nägele, H., Mansourati, J., Mont, L., Anselme, F., Stengel, P., Anselmi, F., Oswald, H., Leclercq, C. Tags: Leads and lead extraction Source Type: research

The ratio of the neutrophil leucocytes to the lymphocytes predicts the outcome after cardiac resynchronization therapy
Aims The low lymphocyte counts and high neutrophil leucocyte fractions have been associated with poor prognosis in chronic heart failure. We hypothesized that the baseline ratio of the neutrophil leucocytes to the lymphocytes (NL ratio) would predict the outcome of chronic heart failure patients undergoing cardiac resynchronization therapy (CRT). Methods and results The qualitative blood counts and the serum levels of N-terminal of the prohormone brain natriuretic peptide (NT-proBNP) of 122 chronic heart failure patients and 122 healthy controls were analysed prospectively in this observational study. The 2-year mortality...
Source: Europace - May 24, 2016 Category: Cardiology Authors: Boros, A. M., Szeplaki, G., Perge, P., Jenei, Z., Bagyura, Z., Zima, E., Molnar, L., Apor, A., Becker, D., Geller, L., Prohaszka, Z., Merkely, B. Tags: Pacing and resynchronization therapy Source Type: research

Safety and efficiency of ventricular pacing prevention with an AAI-DDD changeover mode in patients with sinus node disease or atrioventricular block: impact on battery longevity--a sub-study of the ANSWER trial
Aims This ANSWER (EvaluAtioN of the SafeR mode in patients With a dual chambER pacemaker indication) sub-study assesses safety and effectiveness of SafeR™ and the impact of ventricular pacing (VP) prevention on anticipated device longevity and replacement rate. Methods and results Patients implanted for atrioventricular block (AVB, n = 310) or sinus node dysfunction (SND, n = 336) were randomly assigned to SafeR (n = 314) or DDD (n = 318) and followed for 36 months. Safety, median VP, estimated device longevity (mean difference, 95% confidence interval [CI]), and anticipated replacement rates were analysed by pacing...
Source: Europace - May 24, 2016 Category: Cardiology Authors: Stockburger, M., Defaye, P., Boveda, S., Stancak, B., Lazarus, A., Sipötz, J., Nardi, S., Rolando, M., Moreno, J. Tags: Pacing and resynchronization therapy Source Type: research

The clinical outcome of cardiac resynchronization therapy in post-surgical valvular cardiomyopathy
Conclusions Compared with IDCM, PSVCM was associated with a worse outcome after CRT. Outcomes from PSVCM were similar to ICM. These findings indicate that PSVCM behaves very differently to IDCM after CRT. (Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Leyva, F., Umar, F., Taylor, R. J., Steeds, R. P., Frenneaux, M. P. Tags: Pacing and resynchronization therapy Source Type: research

Low risk of electromagnetic interference between smartphones and contemporary implantable cardioverter defibrillators
Conclusion The risk of EMI between modern smartphones and contemporary ICDs is low. This is probably due to the filters incorporated in the ICDs and low emission by the phones, as well as the small size of the magnets in the smartphones tested. Study registration NCT02330900 (http://www.clinicaltrials.gov). (Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Burri, H., Mondouagne Engkolo, L. P., Dayal, N., Etemadi, A., Makhlouf, A.-M., Stettler, C., Trentaz, F. Tags: Sudden death and ICDs Source Type: research

Early repolarization pattern is the strongest predictor of arrhythmia recurrence in patients with idiopathic ventricular fibrillation: results from a single centre long-term follow-up over 20 years
Conclusion The recurrence rate of ventricular arrhythmias in iVF survivors is high and recurrence might occur delayed (>7 years after the initial event). ERP seems to be highly predictive with respect to early arrhythmia recurrence. Our results highlight that better pathophysiologic understanding of ERP might facilitate a better risk stratification before and an optimal treatment after an iVF event. The high rate of AF and ERP in iVF survivors might indicate an underlying heart disease or myocardial electrical disorder not apparent at the index event. (Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Siebermair, J., Sinner, M. F., Beckmann, B.-M., Laubender, R. P., Martens, E., Sattler, S., Fichtner, S., Estner, H. L., Kääb, S., Wakili, R. Tags: Sudden death and ICDs Source Type: research

Longevity of implantable cardioverter defibrillators: a comparison among manufacturers and over time
Aims Longevity of implantable cardioverter defibrillators (ICDs) is crucial for patients and healthcare systems as replacements impact on infection rates and cost-effectiveness. Aim was to determine longevity using very large databases of two teaching hospitals with a high number of replacements and a rather homogeneous distribution among manufacturers. Methods and results The study population consists of all patients in whom an ICD was inserted in. All ICD manufacturers operating in Switzerland and the Netherlands and all implanted ICDs were included. Implantable cardioverter defibrillator replacements due to normal batt...
Source: Europace - May 24, 2016 Category: Cardiology Authors: von Gunten, S., Schaer, B. A., Yap, S.-C., Szili-Torok, T., Kühne, M., Sticherling, C., Osswald, S., Theuns, D. A. M. J. Tags: Sudden death and ICDs Source Type: research

Phrenic nerve injury during ablation with the second-generation cryoballoon: analysis of the temperature drop behaviour in a large cohort of patients
Conclusion The analysis of the temperature course within the first 40 s after the initiation of the freezing cycle showed that the temperature dropped significantly faster in patients with PNI during ablation in the RSPV. (Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Mugnai, G., de Asmundis, C., Velagic, V., Hünük, B., Ströker, E., Wauters, K., Irfan, G., Overeinder, I., Hacioglu, E., Hernandez-Ojeda, J., Poelaert, J., Verborgh, C., Paparella, G., Brugada, P., Chierchia, G.-B. Tags: Ablation for atrial fibrillation Source Type: research

Typical atrial flutter with muscular type tricuspid atresia
(Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Itoh, T., Kimura, M., Yamada, T. Tags: IMAGES IN ELECTROPHYSIOLOGY Source Type: research

Data on procedural handling and complications of pulmonary vein isolation using the pulmonary vein ablation catheter GOLD(R)
Conclusion The PVAC GOLD® seems to have an acceptable safety profile. The handling is comparable with the previous generation PVAC®. (Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Leitz, P., Güner, F., Wasmer, K., Foraita, P., Pott, C., Dechering, D. G., Zellerhoff, S., Kochhäuser, S., Lange, P. S., Eckardt, L., Mönnig, G. Tags: Ablation for atrial fibrillation Source Type: research

Low rate of asymptomatic cerebral embolism and improved procedural efficiency with the novel pulmonary vein ablation catheter GOLD: results of the PRECISION GOLD trial
Aims This prospective, multicentre study (PRECISION GOLD) evaluated the incidence of asymptomatic cerebral embolism (ACE) after pulmonary vein isolation (PVI) using a new gold multi-electrode radiofrequency (RF) ablation catheter, pulmonary vein ablation catheter (PVAC) GOLD. Also, procedural efficiency of PVAC GOLD was compared with ERACE. The ERACE study demonstrated that a low incidence of ACE can be achieved with a platinum multi-electrode RF catheter (PVAC) combined with procedural manoeuvres to reduce emboli. Methods and results A total of 51 patients with paroxysmal atrial fibrillation (AF) (age 57 ± 9 years...
Source: Europace - May 24, 2016 Category: Cardiology Authors: De Greef, Y., Dekker, L., Boersma, L., Murray, S., Wieczorek, M., Spitzer, S. G., Davidson, N., Furniss, S., Hocini, M., Geller, J. C., Csanadi, Z., for the PRECISION GOLD investigators Tags: Ablation for atrial fibrillation Source Type: research

Repetitive inappropriate implantable cardioverter-defibrillator shocks due to insulation failure with externalized conductor cables of a Biotronik Linox SD ICD lead
(Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Reichlin, T., Kühne, M., Sticherling, C. Tags: EP CASE EXPRESS Source Type: research

Catheter ablation of atrial fibrillation in patients with heart failure: impact of maintaining sinus rhythm on heart failure status and long-term rates of stroke and death
Aims Catheter ablation of atrial fibrillation (AF) in patients with heart failure (HF) can improve left ventricular (LV) function and HF symptoms. We aimed to investigate whether long-term maintenance of sinus rhythm impacts on hard outcomes such as stroke and death. Methods and results An international multicentre registry was compiled from seven centres for consecutive patients undergoing catheter ablation of AF. Long-term freedom from AF was examined in patients with and without HF. The impact of maintaining sinus rhythm on rates of stroke and death was also examined. A total of 1273 patients were included: 171 with HF...
Source: Europace - May 24, 2016 Category: Cardiology Authors: Ullah, W., Ling, L.-H., Prabhu, S., Lee, G., Kistler, P., Finlay, M. C., Earley, M. J., Sporton, S., Bashir, Y., Betts, T. R., Rajappan, K., Thomas, G., Duncan, E., Staniforth, A., Mann, I., Chow, A., Lambiase, P., Schilling, R. J., Hunter, R. J. Tags: Ablation for atrial fibrillation Source Type: research

Mineralocorticoid receptor antagonists and atrial fibrillation: a meta-analysis
Conclusion Our meta-analysis suggests that MRAs may be effective in AF prevention especially in the HF setting. However, there are insufficient data for the widespread use of aldosterone antagonists solely for AF prevention. Larger RCTs with long-term follow-up in different clinical settings are needed to clarify the impact of MRAs on AF. (Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Liu, T., Korantzopoulos, P., Shao, Q., Zhang, Z., Letsas, K. P., Li, G. Tags: Atrial fibrillation Source Type: research

Management of a previously unreported implantable cardioverter-defibrillator lead complication
(Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Mendenhall, G. S., Saba, S., Voigt, A. Tags: EP CASE EXPRESS Source Type: research

Ischaemic stroke in patients with atrial fibrillation with chronic kidney disease undergoing peritoneal dialysis
Conclusion In CKD patients on PD with AF, who had similar ischaemic stroke risk as non-CKD counterparts, warfarin therapy is associated with reduction in risk of ischaemic stroke without a higher risk of ICH. (Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Chan, P.-H., Huang, D., Yip, P.-S., Hai, J., Tse, H.-F., Chan, T.-M., Lip, G. Y. H., Lo, W.-K., Siu, C.-W. Tags: Atrial fibrillation Source Type: research

Familial clustering and subsequent incidence of atrial fibrillation among first-degree relatives in Denmark
Conclusion Familial AF was associated with an increased RR of AF in first-degree relatives compared with the general Danish population. This suggests that familial AF is a major risk factor for developing AF in relatives. (Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Gundlund, A., Christiansen, M. N., Hansen, M. L., Olesen, J. B., Zahir, D., Kober, L., Gislason, G. H., Piccini, J. P., Peterson, E. D., Torp-Pedersen, C., Fosbol, E. L. Tags: Atrial fibrillation Source Type: research

An unusual cause of superior vena cava syndrome after pacemaker implantation
(Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Watanabe, H., Iino, T., Ito, H. Tags: EP CASE EXPRESS Source Type: research

'Real-world management and outcomes of patients with paroxysmal vs. non-paroxysmal atrial fibrillation in Europe: the EURObservational Research Programme-Atrial Fibrillation (EORP-AF) General Pilot Registry
Conclusion In this ‘real-world’ contemporary observational registry, patients with non-paroxysmal AF had a worse outcome, in terms of all-cause mortality, which was related to a more severe clinical profile. The risk of stroke at 1 year was relatively low, perhaps reflecting the high rates of anticoagulation use in this cohort. (Source: Europace)
Source: Europace - May 24, 2016 Category: Cardiology Authors: Boriani, G., Laroche, C., Diemberger, I., Fantecchi, E., Popescu, M. I., Rasmussen, L. H., Dan, G.-A., Kalarus, Z., Tavazzi, L., Maggioni, A. P., Lip, G. Y. H. Tags: Atrial fibrillation Source Type: research

Catheter ablation of atrial fibrillation in chronic heart failure: state-of-the-art and future perspectives
Catheter ablation of atrial fibrillation (AFCA) is a widely recommended treatment for symptomatic atrial fibrillation (AF) patients refractory to pharmacological treatment. Catheter ablation of AF is becoming a therapeutic option also among patients with chronic heart failure (CHF), on top of optimal medical treatment, being this arrhythmia related to a higher risk of death and/or symptom's worsening. In fact, in this setting, clinical evidences are continuously increasing. The present systematic review pools all published experiences concerning AFCA among CHF patients, or patients with structural cardiomyopathies, in orde...
Source: Europace - May 24, 2016 Category: Cardiology Authors: Anselmino, M., Matta, M., Castagno, D., Giustetto, C., Gaita, F. Tags: REVIEW Source Type: research