AFA-Recur: an ESC EORP AFA-LT registry machine-learning web calculator predicting atrial fibrillation recurrence after ablation
ConclusionAFA-Recur, a machine-learning-based probability score predicting 1-year risk of recurrent atrial arrhythmia after AF ablation, achieved good predictive performance, significantly better than currently available tools. The calculator, freely available online, allows patient-specific predictions, favouring tailored therapeutic approaches for the individual patient. (Source: Europace)
Source: Europace - August 25, 2022 Category: Cardiology Source Type: research

In-hospital mortality and major complications related to radiofrequency catheter ablations of over 10 000 supraventricular arrhythmias from 2005 to 2020: individualized case analysis of multicentric administrative data
ConclusionThe present case-based analysis shows an overall low incidence of in-hospital complications after SVT ablation highlighting the overall very good safety profile of SVT ablations in high-volume centres. Further prospective analysis is still warranted to guarantee continuous quality control and optimal patient care. (Source: Europace)
Source: Europace - August 25, 2022 Category: Cardiology Source Type: research

Mobile health vs. standard care after cardiac surgery: results of The Box 2.0 study
ConclusionScheduled self-measurements with mHealth devices could increase the probability of detecting POAF within 3 months after cardiac surgery. The effect of an increase in POAF detection on clinical outcomes needs to be addressed in future research. (Source: Europace)
Source: Europace - August 11, 2022 Category: Cardiology Source Type: research

Identification of Cx43 variants predisposing to ventricular fibrillation in the acute phase of ST-elevation myocardial infarction
ConclusionConnexin 43 variants are associated with increased VF susceptibility in STEMI patients. Restoring Cx43 function may be a potential therapeutic target to prevent PVF in patients with acute MI.Clinical trial registrationClinical Trial Registration:https://clinicaltrials.gov/ct2/show/NCT00859300 (Source: Europace)
Source: Europace - August 9, 2022 Category: Cardiology Source Type: research

Novel dual-reference approach facilitates the activation mapping and catheter ablation of premature atrial complexes with non-pulmonary vein and non-superior vena cava origins
ConclusionAs a novel strategy, the DRA shortens the procedural time and improves both instant and long-term success of PAC ablation, serving as a promising approach in mapping PACs with non-PV and non-SVC origins. (Source: Europace)
Source: Europace - August 9, 2022 Category: Cardiology Source Type: research

The association of coagulation and atrial fibrillation: a systematic review and meta-analysis
ConclusionThese findings suggest that higher levels of coagulation factors are associated with prevalent and incident AF. These associations are most pronounced with prevalent AF in cross-sectional studies. Limited evidence from longitudinal studies suggests a prothrombotic state underlying AF development. (Source: Europace)
Source: Europace - August 9, 2022 Category: Cardiology Source Type: research

New-onset atrial fibrillation following left bundle branch area pacing vs. right ventricular pacing: a two-centre prospective cohort study
ConclusionLeft bundle branch area pacing demonstrated a reduced risk of new-onset AF compared with RVP. Patients with a high ventricular pacing burden might benefit from LBBAP. (Source: Europace)
Source: Europace - August 9, 2022 Category: Cardiology Source Type: research

Personalized ablation vs. conventional ablation strategies to terminate atrial fibrillation and prevent recurrence
ConclusionThe novel PersonALin silico technology allows to unveil all AF-perpetuating areas and personalize ablation by leveraging atrial digital twins. (Source: Europace)
Source: Europace - August 9, 2022 Category: Cardiology Source Type: research

Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference
AbstractDespite marked progress in the management of atrial fibrillation (AF), detecting AF remains difficult and AF-related complications cause unacceptable morbidity and mortality even on optimal current therapy. This document summarizes the key outcomes of the 8th AFNET/EHRA Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA). Eighty-three international experts met in Hamburg for 2 days in October 2021. Results of the interdisciplinary, hybrid discussions in breakout groups and the plenary based on recently published and unpublished observations are summarized...
Source: Europace - July 27, 2022 Category: Cardiology Source Type: research

Arrhythmogenesis of surgical atrial incisions and lesions in Maze procedure: insights from high-resolution mapping of atrial tachycardias
ConclusionsReentry is the main mechanism of the post-Maze ATs. The pro-arrhythmic substrates are most likely caused by surgical incisions and lesions. The slow conduction regions and the protected channels yielded from these areas are the major arrhythmogenic factors. (Source: Europace)
Source: Europace - July 19, 2022 Category: Cardiology Source Type: research

An evaluation of 24 h Holter monitoring in patients with myotonic dystrophy type 1
ConclusionTwenty-four hour Holter monitoring is of added value to routine cardiac screening for all DM1 patients. (Source: Europace)
Source: Europace - July 19, 2022 Category: Cardiology Source Type: research

Catheter ablation for patients with atrial fibrillation and heart failure with reduced and preserved ejection fraction: insights from the KiCS-AF multicentre cohort study
ConclusionAmong AF-HF patients, CA was associated with improved QoL and lower risk of cardiovascular events against drug therapy alone, even for patients with mildly reduced and preserved LVEF. (Source: Europace)
Source: Europace - July 19, 2022 Category: Cardiology Source Type: research

Characterization of circumferential antral pulmonary vein isolation areas resulting from pulsed-field catheter ablation
ConclusionFluoroscopy-guided PFA-PVI frequently results in insufficient isolation areas in the left anterior antral PV segments and enlarged LA isolation areas on the posterior wall/roof, which both may be extensive. To optimize the procedure, full integration of PFA catheter visualization into three-dimensional-mapping systems is needed. (Source: Europace)
Source: Europace - July 19, 2022 Category: Cardiology Source Type: research

Prognostic value of P-wave morphology in general population
ConclusionAbnormalities of P-wave morphology are associated with the risk of all modes of death in general population. After relevant adjustments, PMD was still closely associated with the risk of SCD but not with NSCD or NCD. P-MaxAmp-Z predicted SCD even after adjustments, however, it also retained its association with NSCD and NCD. (Source: Europace)
Source: Europace - July 19, 2022 Category: Cardiology Source Type: research

Use of instant messaging in electrophysiological clinical practice in Latin America: a LAHRS survey
ConclusionsIM apps are used by medical professionals worldwide to share and discuss clinical data and are preferred to many other methods of data sharing and are often used to share many different types of clinical data. They are perceived as a fast and easy way of communication, but medical professionals should be aware of the appropriate use of IM to prevent legal and privacy issues. (Source: Europace)
Source: Europace - June 21, 2022 Category: Cardiology Source Type: research