Bi-atrial high-density mapping reveals inhibition of wavefront turning and reduction of complex propagation patterns as main antiarrhythmic mechanisms of vernakalant
ConclusionsDestabilization of AF by vernakalant is associated with a lowering of fibrillation frequency and inhibition of complex propagation patterns, wave turning, local re-entries, and breakthroughs. (Source: Europace)
Source: Europace - February 26, 2021 Category: Cardiology Source Type: research
Risk stratification of patients undergoing transvenous lead extraction with the ELECTRa Registry Outcome Score (EROS): an ESC EHRA EORP European lead extraction ConTRolled ELECTRa registry analysis
ConclusionEROS successfully identified patients who were at increased risk of significant procedural complications that require urgent surgical intervention. (Source: Europace)
Source: Europace - February 22, 2021 Category: Cardiology Source Type: research
Typical atrial flutter but not fibrillation predicts coronary artery disease in formerly healthy patients
ConclusionThese data suggest that typical atrial flutter constitutes a manifestation of previously asymptomatic CAD. Due to the inclusion criteria, CAD has to be considered silent and chronic in most of the patients. Therefore, the presence of typical atrial flutter in formerly healthy patients should raise suspicion of otherwise silent CAD and initiate further investigations and risk stratification with particular emphasis on the individual CHA2DS2-VASc-Scores. (Source: Europace)
Source: Europace - February 21, 2021 Category: Cardiology Source Type: research
Canadian Registry of Electronic Device Outcomes: remote monitoring outcomes in the Abbott battery performance alert —a multicentre cohort
ConclusionThe use of RM in patients with ICD and cardiac resynchronization therapy under advisory improved detection of PBD, time to device replacement, and was associated with a reduction in all-cause mortality. The factors influencing the association with mortality are unknown and deserve further study. (Source: Europace)
Source: Europace - February 20, 2021 Category: Cardiology Source Type: research
Abnormal pattern of left atrial activation and asynchronous conduction predicted the occurrence of new atrial fibrillation: evidences for Bachmann ’s bundle block in atrial fibrillation pathophysiology
ConclusionsMore pronounced LA asynchrony and abnormal LA activation pattern were associated with new-onset AF. (Source: Europace)
Source: Europace - February 18, 2021 Category: Cardiology Source Type: research
Relationship between procedural volume and complication rates for catheter ablation of atrial fibrillation: a systematic review and meta-analysis
ConclusionThere is an inverse relationship between both hospital and proceduralist AF ablation volume and the incidence of complications. Implementation of minimum hospital and operator AF ablation volume standards should be considered in the context of a broader strategy to identify AF ablation Centers of Excellence. (Source: Europace)
Source: Europace - February 17, 2021 Category: Cardiology Source Type: research
Incorporating coronary calcification by computed tomography into CHA2DS2-VASc score: impact on cardiovascular outcomes in patients with atrial fibrillation
ConclusionCoronary artery calcification is prevalent in AF patients undergoing PVI and independently associated stroke, death and MACE even when adjusted for traditional CHA2DS2-VASc score. Adding CAC as vascular component to the CHA2DS2-VASc score requires further research as it potentially modified the anticoagulation management in 20% of our AF cohort. (Source: Europace)
Source: Europace - February 15, 2021 Category: Cardiology Source Type: research
Diagnostic yield and financial implications of a nationwide electrocardiographic screening programme to detect cardiac disease in the young
ConclusionThe inclusion of an ECG to a health questionnaire is associated with a five-fold increase in the ability to detect disease associated with SCD in young individuals and is more cost effective for detecting serious disease compared with screening with a health questionnaire alone. (Source: Europace)
Source: Europace - February 11, 2021 Category: Cardiology Source Type: research
Deep learning and the electrocardiogram: review of the current state-of-the-art
AbstractIn the recent decade, deep learning, a subset of artificial intelligence and machine learning, has been used to identify patterns in big healthcare datasets for disease phenotyping, event predictions, and complex decision making. Public datasets for electrocardiograms (ECGs) have existed since the 1980s and have been used for very specific tasks in cardiology, such as arrhythmia, ischemia, and cardiomyopathy detection. Recently, private institutions have begun curating large ECG databases that are orders of magnitude larger than the public databases for ingestion by deep learning models. These efforts have demonstr...
Source: Europace - February 10, 2021 Category: Cardiology Source Type: research
Age-related tilt test responses in patients with suspected reflex syncope
ConclusionsAge significantly impacts the haemodynamic pattern of TT responses, starting from the age of 50. Conversely, TT phase —passive or TNG-potentiated—does not significantly influence the type of response, when age-adjusted. Vagal hyperactivity dominates in younger patients, older patients show tendency to vasodepression. (Source: Europace)
Source: Europace - February 10, 2021 Category: Cardiology Source Type: research
Myocardial calcification is associated with endocardial ablation failure of post-myocardial infarction ventricular tachycardia
ConclusionMyocardial calcification was present in 19% of post-MI patients referred for VT ablation and was associated with a high incidence of endocardial ablation failure. (Source: Europace)
Source: Europace - February 7, 2021 Category: Cardiology Source Type: research
Attenuated heart rate recovery is associated with higher arrhythmia recurrence and mortality following atrial fibrillation ablation
ConclusionHeart rate recovery provides additional valuable prognostic information beyond CRF. An impaired HRR is associated with significantly higher rates of arrhythmia recurrence and death following AF ablation. (Source: Europace)
Source: Europace - February 7, 2021 Category: Cardiology Source Type: research
Local catheter impedance drop during pulmonary vein isolation predicts acute conduction block in patients with paroxysmal atrial fibrillation: initial results of the LOCALIZE clinical trial
ConclusionThe magnitude of LI drop was predictive of acute PVI segment conduction block in patients with paroxysmal AF. The thinner posterior wall required smaller LI drops for block compared with the thicker anterior wall. (Source: Europace)
Source: Europace - February 7, 2021 Category: Cardiology Source Type: research
Cryoablation of stellate ganglion for the management of electrical storm: the first reported case
A 64-year-old man with ischaemic cardiomyopathy, cardiac resynchronization therapy with defibrillator and previous ventricular tachycardia (VT) ablation presented due to electrical storm (ES) and recurrent discharges from the device. He was under mexiletine and carvedilol, as he discontinued amiodarone due to thyrotoxicosis. (Source: Europace)
Source: Europace - February 7, 2021 Category: Cardiology Source Type: research
Treatment of atrial fibrillation: is it as easy as A-B-C?
This editorial refers to ‘Relation of outcomes to ABC (Atrial Fibrillation Better Care) pathway adherent care in European patients with atrial fibrillation: an analysis fromthe ESC-EHRA EORPAtrial Fibrillation General Long-Term (AFGen LT) Registry’, by M. Proiettiet al., on pages 174 –183. (Source: Europace)
Source: Europace - February 3, 2021 Category: Cardiology Source Type: research
