145 Remote monitoring of implantable cardioverter-defibrillators: can usage be predicted at a UK tertiary centre?
This study investigated the percentage of patients who do not use RM at a London tertiary centre and identified groups of patients where usage is low. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

144 Implantable cardiac monitors (ICM): quality assurance audit outcomes of an innovative specialist nurse led service.
Background/Objective: A Cardiac Rhythm Management (CRM) nurse-led service was developed in 2015 utilising Medtronic Reveal LINQ ICM devices and advanced remote monitoring technology. Advances in technology have allowed for implantation in a procedure room by CRM specialist nurses. Following implant, all patients received remote monitoring equipment and access to a nurse-led telephone helpline. Daily assessment, management of patient transmissions and follow-up care by scheduled telephone appointments were coordinated by the CRM nurse team. Outcomes were compared from the nurse-led service versus traditional pathway over th...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

143 AV delay optimisation in patients with congenitally corrected transposition of the great arteries.
Background: Adults with congenitally corrected transposition of the great arteries (ccTGA) are at risk of systemic right ventricular failure and cardiac arrhythmias requiring the implantation of pacemakers, ICDs and CRT devices. These devices permit adjustment of the atrioventricular delay to restore atrioventricular synchrony. The importance of atrioventricular delay optimisation in patients with ccTGA has not been investigated. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

142 Do atrial high rate episodes & lt;6  minutes in duration in pacemaker patients increase stroke risk?
Introduction: Atrial fibrillation (AF) is a well-known risk factor for stroke. Recently, episodes as short as 6  minutes in duration have been linked with an increased risk of ischaemic stroke in pacemaker (PPM) patients (Healeyet al., 2012). (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

141 Remote monitoring of ILRs, when is more too much?
Introduction: Remote monitoring has become an accepted and utilised tool for use with implantable cardiac devices: with safety at heart it is easy to see why when it comes to implantable defibrillators. The same is not so evident for implantable loop recorders (ILRs). This paper explores the impact of remote ILR monitoring on cardiac departmental workload. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

140 A retrospective study to assess feasibility of daycase complex device insertion
Introduction: Routinely, patients undergoing elective complex device insertion are discharged the day post-procedure after satisfactory pacing interrogation and chest radiography to confirm lead placements. However, there is a paucity of data relating to early complication rates in patients with device therapy that are discharged on the day of procedure. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

139 Day-case device implantation- a prospective single-centre experience including patient satisfaction data
Introduction; Cardiac rhythm management (CRM) device implantation is associated with serious complications and traditionally patients are admitted overnight for observation. As operative experience has increased, many centres now perform new device implants as day-case procedures. Retrospective studies have evaluated the safety of this approach but there is a lack of prospective data. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

138 Failure of timely referral to acute in-hospital heart failure services
Introduction: Acute heart failure is the leading cause of hospital admissions inpatients 65 years or older. Current guidelines from National institute for Health and Clinical Excellence (UK) recommends all patients admitted with acute heart failure be seen within 24  hours of admission by a specialist multidisciplinary team. Early input from a dedicated heart failure team reduces mortality and hospital readmission rates. The ESC advices appropriate referral and consultation with the multidisciplinary team. We evaluated adherence to these guidelines at our in stitution.  (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

137 Do octogenarians tolerate CRT-P insertion?
Introduction: Cardiac resynchronisation therapy via biventricular pacing (CRT-P) is of established benefit in patients with congestive heart failure (CHF) that are on optimised pharmacotherapy and fulfil specific criteria relating to NYHA class and QRS duration. However, there is a paucity of data relating to procedural tolerability and complication rates in octogenarians undergoing CRT-P implantation.   (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

136 Cardiac resynchronization pacing in patients with chronic heart failure
The objective of this study was to investigate whether cardiac resynchronization therapy improved morbidity among patients with heart failure. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

134 Implantable cardioverter defibrillator use in octogenarians
Introduction: Implantable cardioverter-defibrillators (ICDs) have international guideline endorsement as a therapy to reduced sudden cardiac death in patients with severe systolic cardiac dysfunction. However, their role in octogenarians is uncertain. We sought to describe current practice pertaining to octogenarians and ICD implantation at a tertiary referral centre. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

133 Lower complication rates with MicraTPS versus transvenousVVI pacemakers; a single centre experience
We present our experience utilizing this new technology in a single center retrospective observational study. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

132 The prevalence of upgrade to biventricular pacing after bradycardia pacing is less than 2%: a 12-year series of over 750 patients from a ‘real world’ district general cohort
In this study, we examined a large cohort of patients undergoing bradycardia pacing over a 12-year period and assessed the prevalence of upgrade to biventricular pacing (CRT-D or CRT-P). (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

131 ‘Silent’ atrial tachyarrhythmia and potential cryptogenic stroke: a ‘real-world’ study
Background: Atrial Fibrillation (AFib) and Flutter (AFl) are known to be associated with embolic stroke and current guidelines rightly recommend anticoagulation in these patients to reduce this risk. However, the management of other Atrialtachyarrhythmias (ATAs) in relation to stroke is unclear. The aim of this study was to explore whether ATAs (other than AFib/AFl) could be associated with stroke or progress to AF. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

130 Improving the implementation of anti-coagulation therapy in AF patients at risk of stroke in a primary care setting
Background: Atrial fibrillation (AF) is the most common sustained arrhythmia of the heart and is of increasing prevalence1. There are strong implications of increased stroke risk in AF patients2. In particular, AF related stroke carries a near 50% risk of persisting disability and directly increases costs for treatment by over a third in comparison with non AF stroke patients3,4. As an estimated contributing cause of 15-20% of all strokes, the economic and societal impact of AF is of extreme importance5. To monitor how efficiently stroke prevention is implemented in a primary care setting we will identify those ‘at r...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

129 Atrial flutter in hospital practice: the burden of atrial flutter on a regional cardioversion service, and barriers to referral for ablation
Introduction: Atrial flutter (AFL) is a common arrhythmia with an incidence of 88 per 100 000 person-years. Morbidity from AFL arises from tachycardia, loss of atrial transport, or thromboembolism. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

128 Internal loop recorder ( ‘Reveal’) implantation as a diagnostic tool in patients with unexplained syncope
Introduction: Establishing a precise diagnosis in patients with syncope or palpitations relies on the correlation between symptoms and electrocardiography evidence. In a vast majority of patients the symptoms are paroxysmal and unpredictable. Traditional methods (e.g. external Holter monitoring and Tilt testing etc.) generally fail to provide diagnostic information. Over the last few years, long-term monitoring using an implantable loop recorder (ILR) has gained popularity as a diagnostic tool in the management of these patients. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

127 Setting up a VT ablation service – where to set the bar of patient selection?
Introduction: When developing a VT ablation service, setting an appropriate threshold for patient selection is crucial to ensure that outcomes are optimised. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

126 Implantable loop recorders - diagnostic yield in patients with syncope and presyncope
Syncope is the transient loss of consciousness which results in loss of consciousness and postural tone often leading to collapse and is frequently followed by a spontaneous recovery1. Implantable loop recorders (ILRs) are a reliable means of investigating these events. Current guidelines recommend implantable loop recorders for any patient with syncope that remains unexplained after a conventional work up.1 (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

124 GP-led anticoagulation counselling for non-valvular atrial fibrillation (AF) in the community is neither comprehensive nor accurate: Results from a service improvement project.
Background: Stroke risk in NVAF can be reduced significantly by anticoagulation with either warfarin or the non- vitamin K antagonist (NOACs). NICE recommendations state that NOACs are as efficacious but also associated with significantly less intracranial bleeding compared to Warfarin and in this sense are safer than warfarin. Additionally NOACs do not require regular monitoring of their anticoagulant effects and therefore offer convenience to the patient. However they are not as tried and tested as warfarin and at the time of our study, did not have an available agent to reverse their effects in the event of a bleeding c...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

123 CMRI-assessed left ventricular extra-cellular volume fraction, not left atrial late gadolinium uptake, is related to higher left atrial pressure and increased type 1 collagen telopeptide levels in pre-ablation AF patients
Background: Left atrial (LA) fibrosis assessed by late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) and raised LA pressure predict recurrence of atrial fibrillation (AF) after ablation, however the mechanistic links between LA or left ventricular (LV) fibrosis and AF recurrence are not clear. Using CMR techniques and invasive measurements we tested the hypotheses that LA and LV fibrosis are related to each other, LA pressure, and fibrosis biomarker levels. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

122 Reducing the burden of unnecessary LINQ implantable loop recorder remote downloads by implementing an in-hospital multidisciplinary strategy to individualise management of patients with high volume downloads
Introduction: LINQTM implantable loop recorders (ILRs) were first implanted at Nottingham University Hospitals in January 2015. Unlike conventional ILRs which rely on in-clinic downloads (typically routine three-monthly follow up (FU) or when patient-activated), LINQTMILRs are capable of continuous remote downloads either for routine 3-monthly FU, patient-activated events or pre-specified alerts. This has led to a significant increase in workload for our Pacing clinic (25 conventional ILR in-office downloads per month prior to introduction of LINQTMILRS; 150 LINQTM remote downloads per month after introduction of LINQTMILR...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

121 Effective atrial conducting size does not predict human AF vulnerability
Background: The multiple wavelet hypothesis is an established theory to explain initiation and maintenance of atrial fibrillation (AF). (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

120 Cardiopulmonary exercise testing echocardiography features predicting the safety and efficacy of a central arterio-venous fistula with subgroup analysis assessing the impact of the device on blood pressure control and AF burden
Introduction: A central stent derived arterio-venous iliac fistula using the ROX CouplerTM reduces blood pressure (BP) in patients (pts) with resistant and/or uncontrolled hypertension (HTN). We performed detailed stress echocardiograms (echos) during concurrent cardiopulmonary exercise testing (CPET) pre and post insertion of a ROXTMCoupler for HTN. We evaluated the pre and post ROX Coupler characteristics of pts who might progress to cardiac decompensation. We evaluated the impact of perfect blood pressure control in a sub-analysis of paroxysmal atrial fibrillation (PAF) pts. using continuous heart rhythm monitoring with...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

119 P wave duration and spectral analysis of signal averaged P wave: can this guide us in deciding the extent of af ablation required beyond pulmonary vein isolation? - A prospective study
Background& Purpose: Pulmonary vein isolation (PVI) is an established treatment for paroxysmal atrial fibrillation (PAF) however recurrence can occur despite pulmonary vein (PV) isolation because of abnormal left atrial (LA) substrate which requires additional ablation. The P wave triggered signal averaged ECG (SAECG) has been shown to demonstrate longer P wave duration and higher P wave energies in patients with paroxysmal atrial fibrillation (PAF) compared to controls. We postulated that this technique might be used to identify patients with significant atrial substrate change who may require additional ablation beyo...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

13 SAFE2SCREEN - can patient initiated kiosk-based self-screening provide an opportunity to identify atrial fibrillation within a GP waiting room environment?
Introduction: Atrial fibrillation (AF) remains undiagnosed in many patients in the community. We explored the use of a new electrocardiogram (ECG) screening technique to identify patients with AF who were attending GP surgeries for routine appointments. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

12 Is cardiac resynchronisation therapy more effective in females than males? A comparison of STH patients and the findings of MADIT-CRT
Background: Cardiac resynchronisation therapy (CRT) aims to improve cardiac output in patients with heart failure (HF) and electro-mechanical dyssynchrony of the left ventricle. Response to CRT still displays large individual variations, therefore it is important to identify characteristics which may indicate the success of the device. Differences in sex-specific outcomes for death and heart failure events were examined in a sub-study to the MADIT-CRT study, revealing females to achieve significantly better results from CRT devices than males. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

11 Analysis of trigger factors is one of the important point in the management of patients with stable coronary artery disease and high-grade ventricular arrhythmias
Introduction: To study trigger factors of the ventricular arrhythmias (VA) in patients (pts) with stable coronary artery disease (S СAD) and to evaluate antiarrhythmic effect (AAE) of the individualized and pathogenetic therapy. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

10 Remote monitoring of ILRs, when is more too much?
Introduction: Remote monitoring has become an accepted and utilised tool for use with implantable cardiac devices: with safety at heart it is easy to see why when it comes to implantable defibrillators. The same is not so evident for implantable loop recorders (ILRs). This paper explores the impact of remote ILR monitoring on cardiac departmental workload. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

118 A novel method to determine left atrial compliance in vivo: relationship with markers of remodelling in AF
This study aimed to define a methodology for determining left atrial compliance from date acquired during catheter ablation pro cedures for patients with atrial fibrillation. The relationship between atrial physical properties and other markers of structural remodelling was explored. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

117 The impact of atrial fibrillation on the survival of patients with degenerative aortic stenosis. a prospective clinical study
Introduction: Aortic stenosis has become the most common degenerative valvular heart disease, due to aging of the population. It represents 43% of the cases of degenerative valvular disease. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

116 Survey to evaluate awareness and current practice of venous thromboembolism prevention following electrophysiological procedures in the United Kingdom
Introduction: Invasive electrophysiological (EP) studies require the introduction of multiple catheters into the venous system and a period of immobility, both known pro-thrombotic factors. However there is a paucity of data on strategies to prevent venous thromboembolism (VTE) in this population and they are not explicitly covered in NICE guidelines. The aim of this study was to establish the incidence of VTE in those undergoing EP studies and radiofrequency ablation, excluding patients currently taking therapeutic anti-coagulation, and to survey the current practice within UK EP centres for the prevention of VTE. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

115 Anticoagulation in atrial fibrillation – a single-centre audit on patient education, stroke and bleeding risk assessments and use of direct oral anticoagulants (DOACs)
Objective: To assess adherence to the National Institute of Health and Care Excellence (NICE) guidelines on management of atrial fibrillation in adults, specifically the provision of a personalised package of care and information to patients, and stroke and bleeding risk assessments. To assess the frequency of use of DOACs as the anticoagulant of choice. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

114 P wave morphology and spectral analysis of signal averaged ECG ’S in paroxysmal AF patients: can this explain anatomical basis of paroxysmal AF and their propensity to recurrence
Background& Purpose: Pulmonary vein isolation (PVI) is an established treatment for paroxysmal atrial fibrillation (PAF) however recurrence can occur despite pulmonary vein (PV) isolation because of abnormal left atrial (LA) substrate which requires additional ablation. Signal averaged ECG ’s have been performed on all patients undergoing ablation for PAF. P wave morphology reflects projection of depolarization vector in three dimensional space nd covers both right and left atrial activation., Bachmann’s bundles is considered most important in interatrail conduction pathway.. We p ostulated that this techni...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

113 Review of management of cardiac arrest and predictors of outcome in a large district general hospital “cardiac arrest centre”
Introduction: Cardiac arrest remains a major public health problem with ambulance services attempting resuscitation in 30,000 patients in England annually.  Despite advances in intensive care, post-cardiac arrest survival in the UK remains poor, with pre-hospital factors impacting significantly on outcome. Observational studies have demonstrated improved outcomes with successful Percutaneous Coronary Intervention (PCI). National guidelines have there fore recommended management of out-of-hospital cardiac arrests in designated ‘cardiac arrest centres’ where immediate angiography should be performed if ...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

112 “I don’t know how you can be the decision maker when you don’t understand”: designing a tailored E-health intervention to empower patients living with non-valvular atrial fibrillation
Background: Prevention of thromboembolism is key in individuals with non-valvular atrial fibrillation (NVAF) and nonadherence to oral anticoagulant (OAC) therapy is a frequent causative factor of stroke. Many factors contribute to the complexity of medication nonadherence. Thus, education aimed at changing health behaviors must be tailored to address the unique internal motivations and information needs of those confronted with the daily choice to take a medication to prevent stroke. Delivery of tailored health education and medication reminders may be an effective way to empower individuals with NVAF and in consequence, i...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

111 Supporting initiation of anticoagulation with ‘jack’, a video counselling tool
Introduction: Optimising the use of medicines and ensuring patient adherence is high on the national agenda (1). Anticoagulants are a high risk group of medicines and ensuring that patients have sufficient knowledge and understanding to take their medicines properly is a priority for healthcare professionals (2). Both NICE AF guidance and Medicines Optimisation guidelines encourage joint decision making between prescriber and patient when anticoagulants are started, supported by comprehensive counselling to ensure patients understand their medicines and what to do if something goes wrong. (3) (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

110 Working with community pharmacists to improve anticoagulation new medicine service discussions
Introduction: Community pharmacists (CPs) in England are funded to deliver New Medicine Service (NMS) discussions with patients newly started on Oral Anticoagulation (OAC) to support initiation, and safeguard patient care. NMS has been demonstrated to increase adherence by 10%. A pilot project was undertaken in West Hampshire CCG (WHCCG) to increase the number of NMS OAC reviews through formal referral from the GP to 27 community pharmacies. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

109 Accuracy of test results for Direct Oral Anticoagulants (DOACs) and Warfarin- importance of External Quality Assessment (EQA)
Introduction: Lifelong anticoagulation is widely used in atrial fibrillation (AF) and anticoagulation with warfarin therapy is effective in stroke prevention in AF patients. The introduction of Direct Oral Anticoagulants (DOACS) has increased choice in anticoagulant control. However one concern with DOACs is the measurement of these drugs. It has been established in clinical trials that these drugs are non inferior or superior to warfarin therapy without the need to monitor but in some circumstances we still need to be able to measure the concentrations and effects of these drugs. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

108 The role of permanent pacing following cardiac surgery. Appropriateness and timing of implants: a large tertiary single centre experience.
Introduction: Managing post-operative cardiac patients with bradyarrhythmias for permanent pacing provides a clinical challenge when considering optimum timing for patient safety and potential delayed discharges. Although some guidelines are available, permanent pacemakers (PPM) following cardiac surgery are a heterogeneous group and European Society of Cardiology recommendations include prolonged observation for up to 7 days in high degree AV block (AVB) or 5 days to weeks in sinus node dysfunction. We aimed to evaluate our current practice in the UK ’s largest heart centre, the Barts Heart Centre. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

107 Thoracoscopicepicardial left atrial appendage occlusion in stroke prevention in non-valvular atrial fibrillation - long-term resultes
Background: Oral anticoagulation remainse the standard of care for stroke prevention in atrial fibrillation. However not every patient is feasible for this therapy. Because approximately 90% thrombotic material originate from the left atrial appendage (LAA), it is assumed that the LAA closure might be not inferior to oral anticoagulation. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

106 ECG predictors of ventricular arrhythmia and non arrhythmic death in the subcutaneous implantable cardioverter defibrillator population
Introduction: A minority of patients with implantable cardioverter defibrillators (ICD) receive appropriate treatment for life threatening arrhythmias, whilst a large proportion receive no benefit from device implantation due to non-arrhythmic death. The electrocardiogram (ECG) is a readily available and inexpensive investigation. ECG parameters that predict likelihood of ventricular arrhythmia can improve risk discrimination and have been successfully identified in the transvenous ICD population.   (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

105 Investigation of the transmural action potential duration and repolarization properties of scar borderzone in patients undergoing ventricular tachycardia ablation
Background: Dispersion of action potential duration (APD) and repolarization are important factors in the genesis of ventricular arrhythmia, facilitating functional block and reentry. Present substrate mapping of VT not only fails to account for repolarization of the tissue, but assesses scar/voltage in a planar fashion. However, arrhythmias within the heart do not traverse a one-dimensional course. It is highly likely that the wavefront is heterogeneous, taking complex paths involving endocardium, mid-myocardium and epicardium. The transmural differences of action potential duration (APD), across scar borderzone,  ar...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

103 How is our local AF management? The management of atrial fibrillation (af) in coventry and rugby clinical commissioning group (ccg), england compared to national data and nice (national institute for clinical excellence) 2014
Background: AF is the most common cardiac arrhythmia affecting 2% in the UK.AF carriers 5 fold risk of stroke, with increased stroke mortality, morbidity& longer hospital stay.CHADSVAs guides anti-coagulation ( ≥1 anti-coagulate)Risk factor modification reduces AF reoccurrenceNurse led clinics reduce AF related stroke risk, improve AF management, risk factor reduction whilst providing safe anticoagulation. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

102 Protocol for a systematic search and critical review of studies, in effective strategies to maintain quality of life in adult patients with postural orthostatic tachycardia syndrome utilizing an interpretive approach
Background: POTS is a rare condition which disproportionately affects young women (5:1). Diagnosis is by tilttable which confirms>30 beat per minute heart rate rise on standing. Symptoms for sufferers are variable, including palpitation, dizzyness, poor concentration, "brain fog", pains, anxiety and gastrointestinal disturbances. Current evidence base is limited. Treatment is salt, fluids, compression stockings, tilt exercises and medication. There is no systematic review published in POTS. Meta-analysis is not possible due to heterogeneity of studies (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

99 Temporary pacing optimisation post cardiac surgery. Are we missing a trick?
Introduction: Optimisation of haemodynamic status post cardiac surgery is complex. In the UK, these patients are typically managed by Anaethetists and/or Intesivists. Adjustments in fluid replacement and inotropic support are routine in hypotensive patients, while temporary pacing optimisation is considered less frequently. We hypothesise that for patients with intact atrioventricular (AV) node conduction and appropriate fluid balance, the promotion of intrinsic ventricular conduction may increase blood pressure (BP) and reduce the need for inotropic support. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

101 REVEAL ™ AND CARELINK™ (REAL CARE): minimising diagnostic time in the implantable loop recorder populatioN
Introduction: Syncope accounts for ≈2.7/1000 population/year of presentations to UK healthcare, a figure believed to be underestimated by up to 30% due to misdiagnosis. For some patients the cause of their episode/s may remain unexplained. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

100 Do automatic CRT optimisation algorithms work? A comparison of techniques
Introduction: At least 30% of heart failure patients who receive cardiac resynchronisation therapy (CRT) are ‘non-responders’. Optimisation of pacing intervals, referred to as CRT optimisation, is frequently undertaken in an attempt to reduce non-response and maximise the effectiveness of this therapy. Traditional approaches to CRT optimisation, however, are often expensive and time consuming. Thus, us e of automatic, device based algorithms which utilise features of the intracardiac electrogram (IEGM) for CRT optimisation provide an attractive alternative technique. The aim of this study was to assess effectiv...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

97 Patient self-reported pain and contributing factors during the implant of cardiac implantable electronic devices
Cardiac implantable electronic device (CIED) implantation is becoming an increasingly prevalent part of cardiac rhythm management. Patient experience is a key metric by which the delivery of health care is assessed. For CIED implantation, adequate peri-procedural pain management is central to patient experience. Pocket formation is typically uncomfortable  and local anesthethic is not always sufficient. The 2011 Association of Anaesthetists of Great Britain Guidelines state that operators should develop techniques that permit the patient to undergo the surgical procedure with minimum stress and maximum comfort. Audit ...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

96 Cost effectiveness of a risk-stratified approach to cardiac resynchronisation therapy defibrillators at the time of generator change
Background: Responders to cardiac resynchronisation therapy whose device has a defibrillator component and who do not receive a therapy in the lifetime of the first generator have a very low incidence of appropriate therapy after box change.  We investigated the cost implications of using a risk stratification tool at the time of generator change resulting in these patients being reimplanted with a resynchronisation pacemaker. (Source: Europace)
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research