Early repolarization pattern and its day-to-day dynamic change as markers for ventricular fibrillation in patients with vasospastic angina
This study aimed to clarify the relation between ER and VF in patients with VSA and to investigate the long-term outcomes of ICD therapy. Methods and results This retrospective, observational survey evaluated 265 consecutive VSA patients, including 21 with VF. Their electrocardiogram findings and clinical course were analysed over a mean follow-up of 5.5 ± 3.3 years. Early repolarization was observed in 64 patients (24.2%) and was more frequent in patients with VF history than those without (P = 0.001). Early repolarization was independently associated with VF history. During follow-up, four patients had VF recurre...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Kitamura, T., Fukamizu, S., Hojo, R., Aoyama, Y., Komiyama, K., Nishizaki, M., Sakurada, H., Hiraoka, M. Tags: Cardiac electrophysiology Source Type: research

The limbus of the fossa ovalis: an unusual location for incessant focal atrial tachycardia in children
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Di Pino, A., Caruso, E., Gitto, P. Tags: CASE EXPRESS REPORTS Source Type: research

Propofol sedation administered by cardiologists for patients undergoing catheter ablation for ventricular tachycardia
Aims Propofol sedation has been shown to be safe for atrial fibrillation ablation and internal cardioverter-defibrillator implantation but its use for catheter ablation (CA) of ventricular tachycardia (VT) has yet to be evaluated. Here, we tested the hypothesis that VT ablation can be performed using propofol sedation administered by trained nurses under a cardiologist's supervision. Methods and results Data of 205 procedures (157 patients, 1.3 procedures/patient) undergoing CA for sustained VT under propofol sedation were analysed. The primary endpoint was change of sedation and/or discontinuation of propofol sedation du...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Servatius, H., Höfeler, T., Hoffmann, B. A., Sultan, A., Lüker, J., Schäffer, B., Willems, S., Steven, D. Tags: Cardiac electrophysiology Source Type: research

Solvent-facilitated lead disconnection for battery replacement in patients with pacemakers or implantable cardioverter defibrillators
Conclusion Ethanol has utility as a simple and inexpensive modality for lead disconnection from ICD or PM headers. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Erne, P., Kobza, R., Lehner, M., Resink, T. J. Tags: Leads and lead extraction Source Type: research

Inappropriate high-rate pacing with maximal output due to runaway pacemaker malfunction in a temporary device
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Park, S. M., Son, J.-W., Hong, K.-S. Tags: CASE EXPRESS REPORTS Source Type: research

Active fixation of a thin transvenous left-ventricular lead by a side helix facilitates targeted and stable placement in cardiac resynchronization therapy
Conclusion Active fixation of this 4Fr LV lead by using a side helix, offers flexibility to place the lead precisely in targeted vein segments over a wide range of vein anatomies. The average LV pacing threshold was low at implantation and follow-ups. The lead seems to be extractable and no late dislodgements have been observed. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Keilegavlen, H., Hovstad, T., Faerestrand, S. Tags: Leads and lead extraction Source Type: research

Haemodynamic effects of cardiac resynchronization therapy using single-vein, three-pole, multipoint left ventricular pacing in patients with ischaemic cardiomyopathy and a left ventricular free wall scar: the MAESTRO study
Aims The clinical response to cardiac resynchronization therapy (CRT) is variable. Multipoint left ventricular (LV) pacing could achieve more effective haemodynamic response than single-point LV pacing. Deployment of an LV lead over myocardial scar is associated with a poor haemodynamic response to and clinical outcome of CRT. We sought to determine whether the acute haemodynamic response to CRT using three-pole LV multipoint pacing (CRT3P-MPP) is superior to that to conventional CRT using single-site LV pacing (CRTSP) in patients with ischaemic cardiomyopathy and an LV free wall scar. Methods and results Sixteen patients...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Umar, F., Taylor, R. J., Stegemann, B., Marshall, H., Flannigan, S., Lencioni, M., De Bono, J., Griffith, M., Leyva, F. Tags: Pacing and resynchronization therapy Source Type: research

Prevalence and predictor factors of severe venous obstruction after cardiovascular electronic device implantation
Conclusion In patients with implantable devices, severe venous obstruction prevalence is not negligible and the lack of symptoms does not exclude it. The presence of three leads and sudden cardiac death as indication for implantable devices seem to be associated with the presence of severe venous obstruction/occlusion. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Santini, M., Di Fusco, S. A., Santini, A., Magris, B., Pignalberi, C., Aquilani, S., Colivicchi, F., Gargaro, A., Ricci, R. P. Tags: Pacing and resynchronization therapy Source Type: research

Atrial reverse remodelling is associated with outcome of cardiac resynchronization therapy
Conclusion Patients without atrial and ventricular reverse remodelling have the worst outcome. Patients with only atrial reverse remodelling have improved left ventricular diastolic filling during follow-up and demonstrate a comparable outcome with patients with both atrial and ventricular reverse remodelling. Assessment of atrial reverse remodelling may provide additional prognostic information in determining CRT outcome. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Kloosterman, M., Rienstra, M., Mulder, B. A., Van Gelder, I. C., Maass, A. H. Tags: Pacing and resynchronization therapy Source Type: research

Primary prevention implantable cardioverter-defibrillator and cardiac resynchronization therapy-defibrillator in elderly patients: results of a Spanish multicentre study
Aims Currently, there continues to be a lack of evidence regarding outcomes associated with device-based therapy for ventricular arrhythmias in elderly patients, even more in primary-prevention indications. We aimed to describe the follow-up in terms of efficacy and safety of implantable cardioverter-defibrillator (ICD) therapy in a large cohort of elderly patients. Methods and results Retrospective multicentre study performed in 15 Spanish hospitals. Consecutive patients referred for ICD implantation before 2011 were included. One hundred and sixty-two of 1174 patients (13.8%) ≥75 years were considered as ‘elder...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Exposito, V., Rodriguez-Manero, M., Gonzalez-Enriquez, S., Arias, M. A., Sanchez-Gomez, J. M., Andres La Huerta, A., Bertomeu-Gonzalez, V., Arce-Leon, A., Barrio-Lopez, M. T., Arguedas-Jimenez, H., Seara, J. G., Rodriguez-Entem, F. Tags: Sudden death and ICDs Source Type: research

Retrieval of Medtronic Micra Transcatheter Pacing System after tether removal
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Gerdes, C., Nielsen, J. C. Tags: CASE EXPRESS REPORTS Source Type: research

Sex difference in appropriate shocks but not mortality during long-term follow-up in patients with implantable cardioverter-defibrillators
Aims Implantable cardioverter-defibrillators (ICDs) have been shown to improve survival, although a considerable number of patients never receive therapy. Implantable cardioverter-defibrillators are routinely implanted regardless of sex. There is continuing controversy whether major outcomes differ between men and women. Methods and results In this retrospective single-centre study, 1151 consecutive patients (19% women) undergoing ICD implantation between 1998 and 2010 were followed for mortality and first appropriate ICD shock over 4.9 ± 2.7 years. Sex-related differences were investigated using multivariable Cox ...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Seegers, J., Conen, D., Jung, K., Bergau, L., Dorenkamp, M., Lüthje, L., Sohns, C., Sossalla, S. T., Fischer, T. H., Hasenfuss, G., Friede, T., Zabel, M. Tags: Sudden death and ICDs Source Type: research

Applicability of a risk score for prediction of the long-term benefit of the implantable cardioverter defibrillator in patients receiving cardiac resynchronization therapy
Conclusion A simple risk stratification score comprising five clinical risk factors may help identify CRT patients who are more likely to benefit from the presence of the defibrillator. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Barra, S., Looi, K.-L., Gajendragadkar, P. R., Khan, F. Z., Virdee, M., Agarwal, S. Tags: Sudden death and ICDs Source Type: research

Entrapment of a diagnostic catheter in a novel multipolar basket catheter (Orion™) during right atrial mapping
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Knecht, S., Novak, J., Kühne, M. Tags: CASE EXPRESS REPORTS Source Type: research

Fluoroscopic position of the second-generation cryoballoon during ablation in the right superior pulmonary vein as a predictor of phrenic nerve injury
Aims Phrenic nerve injury (PNI) is the most frequently observed complication during pulmonary vein isolation procedure using the second-generation cryoballoon (CB). Our objective was to analyse the correlation between the fluoroscopic position of the 28 mm CB during ablation in the right superior pulmonary vein (RSPV) and the occurrence of PNI. Methods and results A total of 165 patients having undergone the large 28 mm CB ablation were retrospectively reviewed. Positioning of the CB relative to the cardiac silhouette was classified under fluoroscopic guidance in antero-posterior projection during RSPV ablation. Regarding...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Saitoh, Y., Ströker, E., Irfan, G., Mugnai, G., Ciconte, G., Hünük, B., Velagic, V., Overeinder, I., Tanaka, K., Brugada, P., de Asmundis, C., Chierchia, G.-B. Tags: Ablation for atrial fibrillation Source Type: research

One-year clinical outcome after ablation with a novel multipolar irrigated ablation catheter for treatment of atrial fibrillation: potential implications for clinical use
Aims Pulmonary vein isolation (PVI) is an established therapy for atrial fibrillation (AF). However, PVI remains a time-consuming procedure. A novel multipolar irrigated radiofrequency (RF) ablation catheter (nMARQ™) is aiming to improve PVI. We investigated the influence on procedural parameters and assessed clinical outcomes after PVI using this novel catheter. Methods and results Fifty-eight consecutive patients with paroxysmal AF were equally allocated (n = 29/group) to PVI treatment with (i) the novel multipolar ablation catheter (nMARQ™) and (ii) a standard single-tip ablation catheter (SAC). Study endpo...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Wakili, R., Siebermair, J., Fichtner, S., Sinner, M. F., Klocker, E., Olesch, L., Hilberath, J. N., Sarai, S., Clauss, S., Sattler, S., Kääb, S., Estner, H. L. Tags: Ablation for atrial fibrillation Source Type: research

Safety and efficacy of the nMARQ catheter for paroxysmal and persistent atrial fibrillation
Conclusion The nMARQ catheter is a highly effective tool for treatment of paroxysmal and persistent AF. Nevertheless, the occurrence of life-threatening oesophageal fistulas is of major concern and requires further investigation. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Vurma, M., Dang, L., Brunner-La Rocca, H.-P., Sütsch, G., Attenhofer-Jost, C. H., Duru, F., Scharf, C. Tags: Ablation for atrial fibrillation Source Type: research

Incidence of real-time recordings of pulmonary vein potentials using the third-generation short-tip cryoballoon
Conclusion The rate of visualization of RT recordings is significantly high during third-generation CB-ST ablation. Real-time recordings can be visualized in ~87.1% of veins with this novel cryoballoon. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Chierchia, G.-B., Mugnai, G., Ströker, E., Velagic, V., Hünük, B., Moran, D., Hacioglu, E., Poelaert, J., Verborgh, C., Umbrain, V., Beckers, S., Ruggiero, D., Brugada, P., de Asmundis, C. Tags: Ablation for atrial fibrillation Source Type: research

Real-world persistence and adherence to oral anticoagulation for stroke risk reduction in patients with atrial fibrillation
Aim To assess persistence and adherence to rivaroxaban, dabigatran, and vitamin K antagonist (VKA) treatment in primary care patients with non-valvular atrial fibrillation (AF) newly starting anticoagulant therapy. Methods and results Prescription data for oral anticoagulants were obtained from 7265 eligible patients from primary care practices across Germany. Persistence with and adherence to anticoagulation were assessed in anticoagulant-naïve patients with AF newly treated with dabigatran, rivaroxaban, or VKA during follow-up periods of at least 180 days, respectively 360 days after the prescription date. Persistence...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Beyer-Westendorf, J., Ehlken, B., Evers, T. Tags: Atrial fibrillation Source Type: research

Serum 25-hydroxyvitamin D and the incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study
Conclusion Low serum 25(OH)D was not associated with incident AF in a community-based cohort and in a meta-analysis of prospective studies. A possible association in younger individuals warrants further investigation. (Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Alonso, A., Misialek, J. R., Michos, E. D., Eckfeldt, J., Selvin, E., Soliman, E. Z., Chen, L. Y., Gross, M. D., Lutsey, P. L. Tags: Atrial fibrillation Source Type: research

Hospitalizations in patients with atrial fibrillation: an analysis from ROCKET AF
We described the frequency of and reasons for hospitalization during study follow-up and utilized Cox proportional hazards models to assess for baseline characteristics associated with all-cause hospitalization. Of 14 171 patients, 14% were hospitalized at least once. Of 2614 total hospitalizations, 41% were cardiovascular including 4% for AF; of the remaining, 12% were for bleeding. Compared with patients not hospitalized, hospitalized patients were older (74 vs. 72 years), and more frequently had diabetes (46 vs. 39%), prior MI (23 vs. 16%), and paroxysmal AF (19 vs. 17%), but less frequently had prior transient ischaemi...
Source: Europace - August 4, 2016 Category: Cardiology Authors: DeVore, A. D., Hellkamp, A. S., Becker, R. C., Berkowitz, S. D., Breithardt, G., Hacke, W., Halperin, J. L., Hankey, G. J., Mahaffey, K. W., Nessel, C. C., Singer, D. E., Fox, K. A. A., Patel, M. R., Piccini, J. P., on behalf of the ROCKET AF Steering Com Tags: Atrial fibrillation Source Type: research

Current and future developments in the field of central sleep apnoea
Central sleep apnoea (CSA) occurs in ~30–50% of patients with heart failure (HF) with reduced left ventricular ejection fraction (LVEF) and in as much as in 18–30% of patients with preserved LVEF. In HF patients, it is characterized by periodic breathing also known as the Cheyne–Stokes respiration followed by pauses of breathing. Central sleep apnoea remains often unrecognized due to its chronic and insidious incidences. Patients may report excessive daytime somnolence, poor sleep quality, nocturnal angina, recurrent arrhythmias, refractory HF symptoms, or demonstrate abnormal respiratory pattern or apnoe...
Source: Europace - August 4, 2016 Category: Cardiology Authors: Bekfani, T., Abraham, W. T. Tags: REVIEW Source Type: research

Catheter ablation for atrial fibrillation in congestive heart failure: consider the upside, consider the downside
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Wong, G. R., Kalman, J. M. Tags: EDITORIALS Source Type: research

Last call on nMARQ™ safety
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Dekker, L. R. Tags: EDITORIALS Source Type: research

Challenges in atrial fibrillation beyond stroke prevention: keeping patients out of the hospital
(Source: Europace)
Source: Europace - August 4, 2016 Category: Cardiology Authors: Pokorney, S. D., Steinberg, B. A. Tags: EDITORIALS Source Type: research

Do we need intracardiac echo to guide ablation of ventricular arrhythmias from the papillary muscles?
This editorial refers to ‘Intracardiac echo-facilitated 3D electroanatomical mapping of ventricular arrhythmias from the papillary muscles: assessing the “fourth dimension” during ablation’ by R. Proiettiet al., on pages21 –28. (Source: Europace)
Source: Europace - August 2, 2016 Category: Cardiology Source Type: research

Intracardiac echo-facilitated 3D electroanatomical mapping of ventricular arrhythmias from the papillary muscles: assessing the ‘fourth dimension’ during ablation
ConclusionAn echo-facilitated 3D electroanatomical mapping allows for real-time creation of precise geometries of cardiac chambers and endocavitary structures. This is useful during procedures such as catheter ablation of VAs originating from PMs, which require detailed representation of anatomical landmarks. Routine adoption of this technique should be considered to improve outcomes of PM VA ablation. (Source: Europace)
Source: Europace - August 1, 2016 Category: Cardiology Source Type: research

Cardiac resynchronization therapy: mechanisms of action and scope for further improvement in cardiac function
AbstractAimsCardiac resynchronization therapy (CRT) may exert its beneficial haemodynamic effect by improving ventricular synchrony and improving atrioventricular (AV) timing. The aim of this study was to establish the relative importance of the mechanisms through which CRT improves cardiac function and explore the potential for additional improvements with improved ventricular resynchronization.Methods and ResultsWe performed simulations using the CircAdapt haemodynamic model and performed haemodynamic measurements while adjusting AV delay, at low and high heart rates, in 87 patients with CRT devices. We assessed QRS dura...
Source: Europace - July 13, 2016 Category: Cardiology Source Type: research

J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge
Sudden cardiac deathJ waveBrugada syndromeEarly repolarization syndromeCardiac arrhythmiaVentricular fibrillationInherited cardiac arrhythmia syndrome (Source: Europace)
Source: Europace - July 13, 2016 Category: Cardiology Source Type: research

Strategies for prediction and early detection of atrial fibrillation: present and future
This editorial refers to ‘CHA2DS2-VASc score and blood biomarkers to identify patients with atrial high-rate episodes and paroxysmal atrial fibrillation’ by P. Wakulaet al., on pages 544 –551. (Source: Europace)
Source: Europace - July 7, 2016 Category: Cardiology Source Type: research

Association of pre-ablation level of potential blood markers with atrial fibrillation recurrence after catheter ablation: a meta-analysis
ConclusionIncreased pre-ablation level of ANP, BNP, NT-pro-BNP, IL-6, C-reactive protein, LDL, and TIMP-2 was associated with greater risk of AF recurrence after RFCA. (Source: Europace)
Source: Europace - July 6, 2016 Category: Cardiology Source Type: research

Predictors of sinus rhythm after electrical cardioversion of atrial fibrillation: results from a data mining project on the Flec-SL trial data set
ConclusionsPharmacological conversion of persistent AF with flecainide without the need for electrical cardioversion is a powerful and independent predictor of maintenance of SR. A strategy of flecainide pretreatment for 48 h prior to planned electrical cardioversion may be a useful planning of a strategy of long-term rhythm control. (Source: Europace)
Source: Europace - July 2, 2016 Category: Cardiology Source Type: research

Contact-force-guided vs. contact-force-blinded catheter ablation of typical atrial flutter: a prospective study
ConclusionsCatheter ablation of AFL guided by real-time CF assessment results in a significant reduction in total RF delivery time. Real-time CF measurements facilitate the maintenance of homogenous efficient contact all along the CTI, particularly in the anterior segment where CF is generally lower. (Source: Europace)
Source: Europace - July 2, 2016 Category: Cardiology Source Type: research

Smart detection of atrial fibrillation †
ConclusionThe algorithm tested reliably discriminated between SR and AF based on pulse wave signals from a smartphone camera only. Implementation of this algorithm into a smartwatch is the next logical step. (Source: Europace)
Source: Europace - July 1, 2016 Category: Cardiology Source Type: research

Reliability of luminal oesophageal temperature monitoring during radiofrequency ablation of atrial fibrillation: insights from probe visualization and oesophageal reconstruction using magnetic resonance imaging
ConclusionDue to the unknown exact lateral position of the LET probe within the oesophagus, the measured temperature does not necessarily reflect the maximal LET. The absence of LET increase does not rule out significant temperature increase within the oesophagus. Consequently, the temperature information of the linear multipolar probe should be used with caution. (Source: Europace)
Source: Europace - June 29, 2016 Category: Cardiology Source Type: research

Lead-related infective endocarditis: factors influencing the formation of large vegetations
The objective of the present study was to evaluate risk factors of ILV and their impact on vegetation size.Methods and resultsClinical data of 500 patients with LRIE undergoing transvenous lead extraction in 2006 –15 were retrospectively analysed. The study population consisted of 352 patients with the presence of vegetations (giant,>3 cm; large, 2.0 –2.9 cm; moderate-sized, 1.0–1.9 cm; and small,
Source: Europace - June 29, 2016 Category: Cardiology Source Type: research

Non-vitamin K oral anticoagulants in patients with atrial fibrillation after cardiac surgery: the results of the European Heart Rhythm Association Survey
The purpose of this European Heart Rhythm Association survey was to assess the current practice concerning the use of oral anticoagulation in patients with post-operative atrial fibrillation (pre-existing or new-onset). The survey highlights the considerable heterogeneity of the type of anticoagulation, with 25% of the centres never using the non-vitamin K antagonist oral anticoagulants (NOACs) in this setting, as well the timing of oral anticoagulation initiation, the use and dosing of low-molecular-weight heparins, and the duration of anticoagulation when sinus rhythm is restored. One-third of the centres stated that the...
Source: Europace - June 28, 2016 Category: Cardiology Authors: Vranckx, P., Potpara, T., Dagres, N., Heidbuchel, H. Tags: EP WIRE Source Type: research

Tilt testing results are influenced by tilt protocol
Aims It is unknown how the return to supine position influences duration of loss of consciousness (LOC) and cardioinhibition during tilt test. Methods and results Retrospective analysis of two datasets containing records of patients who underwent tilt testing for unexplained syncope in two centres was performed. Patients, totalling 1232, were included in the study: 262 in a Swedish centre and 970 patients in a Polish centre. In Sweden, tilt table with tilt-down time (TDT) of 18 s was used (Group II). In Poland, two different tilt tables were used, one of them with TDT of 10 s (Group I, n = 325), and the other with TDT of ...
Source: Europace - June 28, 2016 Category: Cardiology Authors: Zysko, D., Fedorowski, A., Nilsson, D., Rudnicki, J., Gajek, J., Melander, O., Sutton, R. Tags: Syncope and event loop recorders Source Type: research

Modified criteria for carotid sinus hypersensitivity are associated with increased mortality in a population-based study
Conclusion Carotid sinus hypersensitivity defined according to Kerr criteria is associated with increased mortality. This raises an interesting question as to the suitability of the current criteria used to define CSH. (Source: Europace)
Source: Europace - June 28, 2016 Category: Cardiology Authors: McDonald, C., Pearce, M. S., Newton, J. L., Kerr, S. R. J. Tags: Syncope and event loop recorders Source Type: research

Expert cardiologists cannot distinguish between Brugada phenocopy and Brugada syndrome electrocardiogram patterns
Conclusion Our results provide strong evidence that BrP and BrS ECG patterns are visually identical and indistinguishable. These findings support the use of systematic diagnostic criteria for differentiating BrP vs. BrS as an erroneous diagnosis may have a negative impact on patient morbidity and mortality. (Source: Europace)
Source: Europace - June 28, 2016 Category: Cardiology Authors: Gottschalk, B. H., Anselm, D. D., Brugada, J., Brugada, P., Wilde, A. A., Chiale, P. A., Perez-Riera, A. R., Elizari, M. V., De Luna, A. B., Krahn, A. D., Tan, H. L., Postema, P. G., Baranchuk, A. Tags: Channelopathies Source Type: research

Phenotypic expression is a prerequisite for malignant arrhythmic events and sudden cardiac death in arrhythmogenic right ventricular cardiomyopathy
Conclusions The ARVC phenotypic expression is a prerequisite for the occurrence of life-threatening arrhythmias in DS-gene mutation carriers. The vast majority of malignant arrhythmic events occurred in patients with an overt disease phenotype and major risk factors suggesting that this subgroup most benefits from ICD therapy. (Source: Europace)
Source: Europace - June 28, 2016 Category: Cardiology Authors: Zorzi, A., Rigato, I., Pilichou, K., Perazzolo Marra, M., Migliore, F., Mazzotti, E., Gregori, D., Thiene, G., Daliento, L., Iliceto, S., Rampazzo, A., Basso, C., Bauce, B., Corrado, D. Tags: Channelopathies Source Type: research

Standard heart rate variability spectral analysis: does it purely assess cardiac autonomic function?
(Source: Europace)
Source: Europace - June 28, 2016 Category: Cardiology Authors: Sidorenko, L., Kraemer, J. F., Wessel, N. Tags: CASE EXPRESS REPORTS Source Type: research

T-wave area as biomarker of clinical response to cardiac resynchronization therapy
Aims There is increasing evidence that left bundle branch block (LBBB) morphology on the electrocardiogram is a positive predictor for response to cardiac resynchronization therapy (CRT). We previously demonstrated that the vectorcardiography (VCG)-derived T-wave area predicts echocardiographic CRT response in LBBB patients. In the present study, we investigate whether the T-wave area also predicts long-term clinical outcome to CRT. Methods and results This is a retrospective study consisting of 335 CRT recipients. Primary endpoint were the composite of heart failure (HF) hospitalization, heart transplantation, left ventr...
Source: Europace - June 28, 2016 Category: Cardiology Authors: Vegh, E. M., Engels, E. B., van Deursen, C. J. M., Merkely, B., Vernooy, K., Singh, J. P., Prinzen, F. W. Tags: Electrocardiology and risk stratification Source Type: research

A novel approach to detect phrenic nerve stimulation in cardiac resynchronization therapy
(Source: Europace)
Source: Europace - June 28, 2016 Category: Cardiology Authors: Kiblboeck, D., Siostrzonek, P., Reisinger, J. Tags: CASE EXPRESS REPORTS Source Type: research

Non-sustained wide complex tachycardia: an underappreciated sign to aid in diagnosis
Aims The electrocardiographic (ECG) signs used to differentiate ventricular tachycardia (VT) from supraventricular tachycardia (SVT) with aberrancy are specific but not highly sensitive. The purpose of this study was to define the utility of an underappreciated form of atrioventricular (AV) dissociation at the onset of tachycardia, a single dissociated P wave, in the differentiation of non-sustained monomorphic wide complex tachycardia (WCT) in hospitalized patients. Methods and results We prospectively analysed tracings from 102 consecutive hospitalized patients who had an episode of non-sustained (≥5 beats,
Source: Europace - June 28, 2016 Category: Cardiology Authors: Padala, S. K., Sidhu, M. S., Brown, J. R., Zipursky, J. S., Steckman, D. A., Parikh, D. R., Greenberg, M. L. Tags: Electrocardiology and risk stratification Source Type: research

Focal atrial tachycardia originating from the septal mitral annulus: electrocardiographic and electrophysiological characteristics and radiofrequency ablation
This study sought to investigate electrocardiographic characteristics, electrophysiological features, and radiofrequency ablation in patients with focal atrial tachycardia (AT) originating from the septal mitral annulus. Methods and results In 13 patients with AT originating from the septal mitral annulus, activation mapping was performed to identify the earliest activation site. Successful ablation was performed through either a transseptal (n = 12) or a retrograde aortic approach (n = 1). As confirmed by electrogram recordings, fluoroscopy, and three-dimensional (3D) mapping, successful ablation sites were located in th...
Source: Europace - June 28, 2016 Category: Cardiology Authors: Wang, Y., Li, D., Zhang, J., Han, Z., Wang, Y., Ren, X., Li, X., Chen, F. Tags: Cardiac electrophysiology Source Type: research

Transbaffle catheter ablation of atrial re-entrant tachycardia within the pulmonary venous atrium in adult patients with congenital heart disease
Conclusion Transbaffle access to the PVA for ablation of atrial re-entrant tachycardia is feasible, less invasive than alternative approaches and can be safely applied in patients after Mustard procedure or with a Fontan circulation. However, the rigidity of prosthetic material may preclude baffle puncture at least in a subset of those patients. (Source: Europace)
Source: Europace - June 28, 2016 Category: Cardiology Authors: Krause, U., Backhoff, D., Klehs, S., Schneider, H. E., Paul, T. Tags: Cardiac electrophysiology Source Type: research

Incidence, predictors, and outcome of inadvertent malposition of transvenous pacing or defibrillation lead in the left heart
Aims Inadvertent lead malposition (ILM) in the left heart is a potential cause of thromboembolism and, therefore, a complication of heart rhythm device implantation [HRDI: pacemaker, implantable cardioverter defibrillator (ICD), cardiac resynchronization therapy (CRT)]. The aim of the study was to report the incidence and clinical outcome of ILM. Methods and results Postoperative lateral and posterior–anterior chest X-rays of all consecutive patients undergoing HRDI from 2007 through 2012 were retrospectively analysed. During the study period, 2579 patients underwent HRDI at our institution. ILM was present in six p...
Source: Europace - June 28, 2016 Category: Cardiology Authors: Ohlow, M.-A., Roos, M., Lauer, B., Von Korn, H., Geller, J. C. Tags: Leads and lead extraction Source Type: research

Initial experience with the TightRail™ Rotating Mechanical Dilator Sheath for transvenous lead extraction
Conclusion Our preliminary data with small sample size show that TightRail™ Mechanical Dilator Sheath is a new useful tool for chronically implanted pacemaker (PM)/ICD leads. Continued investigation including large patient cohort is required to evaluate success and complication rates in comparison to other tools and techniques. (Source: Europace)
Source: Europace - June 28, 2016 Category: Cardiology Authors: Aytemir, K., Yorgun, H., Canpolat, U., Sahiner, M. L., Kaya, E. B., Evranos, B., Özer, N. Tags: Leads and lead extraction Source Type: research

Pacemakers implantation and radiofrequency catheter ablation procedures during medical missions in Morocco: an 8-year experience
Conclusion Radiofrequency catheter ablation for arrhythmias in developing countries is technically challenging but feasible, despite technical and cultural difficulties. (Source: Europace)
Source: Europace - June 28, 2016 Category: Cardiology Authors: Bun, S.-S., Latcu, D. G., Errahmouni, A., Zarqane, N., Yaïci, K., Moustaghfir, A., Tazi-Mezalek, A., Saoudi, N. Tags: Pacing and resynchronization therapy Source Type: research