Occurrence of simultaneous cathodal –anodal capture with left ventricular quadripolar leads for cardiac resynchronization therapy: an electrocardiogram evaluation
ConclusionIn our experience, additional anodal capture by the proximal LV ring during LV pacing is provable in most recipients of a resynchronization device equipped with a multipolar LV lead. (Source: Europace)
Source: Europace - December 2, 2016 Category: Cardiology Source Type: research

Association of pre-ablation level of vitamin D with atrial fibrillation recurrence after catheter ablation: reply
Vitamin D was not involved in our article, because there had been no studies focusing on the association of vitamin D and atrial fibrillation (AF) recurrence after catheter ablation.1 (Source: Europace)
Source: Europace - November 17, 2016 Category: Cardiology Source Type: research

European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulación Cardiaca y Electrofisiologia (SOLAECE)
(Source: Europace)
Source: Europace - November 17, 2016 Category: Cardiology Source Type: research

Impact of sedation vs. general anaesthesia on percutaneous epicardial access safety and procedural outcomes
ConclusionsChoice of anaesthesia for EpiAcc does not appear to significantly affect safety and procedural or clinical outcomes. For patients in whom anaesthesia may pose increased risk, it is reasonable to obtain epicardial access under sedation. (Source: Europace)
Source: Europace - November 15, 2016 Category: Cardiology Source Type: research

Coincidental ganglionated plexus modification during radiofrequency pulmonary vein isolation and post-ablation arrhythmia recurrence
ConclusionCoincidentally elicited VR during radiofrequency PVI in patients with paroxysmal AF do not appear to be related to lower risk of arrhythmia recurrence. This may mean that, even if a VR is truly a sign of coincidental ablation of a ganglionated plexus, this does not necessarily mean that a therapeutic modification has been effected, at least to a degree associated with clinical benefit. (Source: Europace)
Source: Europace - November 10, 2016 Category: Cardiology Source Type: research

Pre-participation cardiovascular evaluation for athletic participants to prevent sudden death: Position paper from the EHRA and the EACPR, branches of the ESC. Endorsed by APHRS, HRS, and SOLAECE
(Source: Europace)
Source: Europace - November 4, 2016 Category: Cardiology Source Type: research

Multiple leadless pacemakers implanted in the right ventricle of swine
Conclusion Multiple leadless pacemakers implanted in the RV do not appear to impact cardiac function. Therefore, it appears safe to implant multiple leadless pacemakers in the same heart. (Source: Europace)
Source: Europace - November 2, 2016 Category: Cardiology Authors: Chen, K., Zheng, X., Dai, Y., Wang, H., Tang, Y., Lan, T., Zhang, J., Tian, Y., Zhang, B., Zhou, X., Bonner, M., Zhang, S. Tags: Basic Science Source Type: research

Combined leadless pacemaker and subcutaneous implantable defibrillator therapy: feasibility, safety, and performance
Conclusion Combined LP and S-ICD therapy appears feasible in all animal experiments (n = 2) and in one human subject. No interference in sensing and pacing during intrinsic and paced rhythm was noted in both animal and human subjects. However, induced arrhythmia testing was not performed in the patient. Defibrillation therapy did not seem to affect LP function. More data on safety and performance are needed. (Source: Europace)
Source: Europace - November 2, 2016 Category: Cardiology Authors: Tjong, F. V. Y., Brouwer, T. F., Smeding, L., Kooiman, K. M., de Groot, J. R., Ligon, D., Sanghera, R., Schalij, M. J., Wilde, A. A. M., Knops, R. E. Tags: Basic Science Source Type: research

Syncope in patients paced for atrioventricular block
Conclusions Cardiac pacing is highly effective in preventing syncopal recurrences when AVB is documented. Syncope may recur in a non-negligible minority of paced patients when AVB is suspected but not documented and in patients without SHD. (Source: Europace)
Source: Europace - November 2, 2016 Category: Cardiology Authors: Aste, M., Oddone, D., Donateo, P., Solano, A., Maggi, R., Croci, F., Solari, D., Brignole, M. Tags: Syncope and event loop recorders Source Type: research

The first reported case of a transvenous left ventricular pacing lead of cardiac resynchronization therapy causing aggravation of coronary atherosclerosis
(Source: Europace)
Source: Europace - November 2, 2016 Category: Cardiology Authors: Sato, A., Hasegawa, Y., Minamino, T. Tags: Case Express Reports Source Type: research

Incidence of arrhythmias in a large cohort of patients with current implantable cardioverter-defibrillators in Spain: results from the UMBRELLA Registry
Aims The benefit of implantable cardioverter-defibrillators (ICDs) in patients at risk of sudden death has been established in randomized clinical trials (RCTs) using the ICD models available at the time. However, observational large-scale data on the incidence of arrhythmias in up-to-date ICDs implanted according to the current guidelines are scarce. The aim was to assess the incidence of arrhythmias in a large, current ICD population based on a blinded peer review of the detected episodes. Methods and results UMBRELLA is a multicentre, observational registry of ICD patients followed by remote monitoring. Stored episodes...
Source: Europace - November 2, 2016 Category: Cardiology Authors: Fontenla, A., Martinez-Ferrer, J. B., Alzueta, J., Vinolas, X., Garcia-Alberola, A., Brugada, J., Peinado, R., Sancho-Tello, M. J., Cano, A., Fernandez-Lozano, I. Tags: Sudden death and ICDs Source Type: research

Brockenbrough needle markedly deformed by vein tortuosity
(Source: Europace)
Source: Europace - November 2, 2016 Category: Cardiology Authors: Mitacchione, G., Marazzi, R., De Ponti, R. Tags: Images in Electrophysiology Source Type: research

Different impact of long-detection interval and anti-tachycardia pacing in reducing unnecessary shocks: data from the ADVANCE III trial
Aims A long-detection interval (LDI) (30/40 intervals) has been proved to be superior to a standard-detection interval (SDI) (18/24 intervals) in terms of reducing unnecessary implantable cardioverter defibrillator (ICD) therapies. To better evaluate the different impact of LDI and anti-tachycardia pacing (ATP) on reducing painful shocks, we assessed all treated episodes in the ADVANCE III trial. Methods and results A total of 452 fast (200 ms
Source: Europace - November 2, 2016 Category: Cardiology Authors: Arenal, A., Proclemer, A., Kloppe, A., Lunati, M., Martinez Ferrer, J. B., Hersi, A., Gulaj, M., Wijffels, M. C. E. F., Santi, E., Manotta, L., Mangoni, L., Gasparini, M. Tags: Sudden death and ICDs Source Type: research

Atrial fibrillation driven by scar-related atrial flutter
(Source: Europace)
Source: Europace - November 2, 2016 Category: Cardiology Authors: Itoh, T., Yamada, T., Okumura, K. Tags: Images in Electrophysiology Source Type: research

High plasma level of soluble RAGE is independently associated with a low recurrence of atrial fibrillation after catheter ablation in diabetic patient
Conclusion High plasma level of sRAGE was independently associated with low AF recurrence after catheter ablation in diabetic patients, especially those with paroxysmal AF. (Source: Europace)
Source: Europace - November 2, 2016 Category: Cardiology Authors: Yang, P.-S., Kim, T.-h., Uhm, J.-S., Park, S., Joung, B., Lee, M.-H., Pak, H.-N. Tags: Ablation for atrial fibrillation Source Type: research

Concomitant cryoballoon ablation and percutaneous closure of left atrial appendage in patients with atrial fibrillation
Aims Pulmonary veins (PVs) isolation is the cornerstone of atrial fibrillation (AF) ablation and can be achieved either by conventional radiofrequency ablation or by cryoenergy. Left atrial appendage (LAA) closure has been proposed as alternative treatment to vitamin K antagonists (VKA). We aimed to evaluate the feasibility of combining cryoballoon (CB) ablation and LAA occlusion in patients with AF and a high thromboembolic risk or contraindication to antithrombotic therapy. Methods and results Thirty-five patients (28 males, 74 ± 2 years) underwent CB ablation. Left atrial appendage occlusion was carried out by u...
Source: Europace - November 2, 2016 Category: Cardiology Authors: Fassini, G., Conti, S., Moltrasio, M., Maltagliati, A., Tundo, F., Riva, S., Dello Russo, A., Casella, M., Majocchi, B., Zucchetti, M., Russo, E., Marino, V., Pepi, M., Tondo, C. Tags: Ablation for atrial fibrillation Source Type: research

Flecainide-metoprolol combination reduces atrial fibrillation clinical recurrences and improves tolerability at 1-year follow-up in persistent symptomatic atrial fibrillation
This study is a monocentric, prospective, randomized, open-blinded trial on 173 patients with a recent episode of paroxysmal or persistent AF. Patients were randomized into group A (flecainide + metoprolol; n = 80), group B (flecainide only; n = 72), or group C (metoprolol only; n = 21). Main exclusion criteria were recent acute coronary syndrome, heart failure New York Heart Association class III–IV, left ventricular ejection fraction
Source: Europace - November 2, 2016 Category: Cardiology Authors: Capucci, A., Piangerelli, L., Ricciotti, J., Gabrielli, D., Guerra, F. Tags: Atrial fibrillation Source Type: research

Conduction recovery at the mitral isthmus triggers atrial fibrillation in a patient with rate-dependent 'block and recurrent atrial fibrillation after previous pulmonary vein isolation and left atrial linear ablation
(Source: Europace)
Source: Europace - November 2, 2016 Category: Cardiology Authors: Brunelli, M., Dähne, T., Cima, A., Geller, J. C. Tags: Case Express Reports Source Type: research

Atrial fibrillation and risk of stroke: a nationwide cohort study
Conclusions Stroke/TE/TIA risk was particularly increased when prior stroke/TE/TIA was present. Atrial fibrillation is associated with an increase in risk of stroke/TE/TIA in the absence of other risk factors but only a moderate increase in risk when other risk factors are present. (Source: Europace)
Source: Europace - November 2, 2016 Category: Cardiology Authors: Christiansen, C. B., Gerds, T. A., Olesen, J. B., Kristensen, S. L., Lamberts, M., Lip, G. Y. H., Gislason, G. H., Kober, L., Torp-Pedersen, C. Tags: Atrial fibrillation Source Type: research

Heart failure due to right ventricular apical pacing: the importance of flow patterns
In patients receiving permanent cardiac electrical stimulation, a high burden of apical right ventricular pacing is associated with an increased incidence of heart failure. Despite the large body of electrocardiographic, echocardiographic, and pathological data, mechanisms underlying this serious complication are not fully understood. Moreover, the empirical use of alternative right ventricular pacing sites, both in the experimental and in the clinical setting, has not provided better results in terms of clinical outcome. Recent data derived by echocardiographic particle image velocimetry of intracardiac flows have shown a...
Source: Europace - November 2, 2016 Category: Cardiology Authors: Cicchitti, V., Radico, F., Bianco, F., Gallina, S., Tonti, G., De Caterina, R. Tags: Review Source Type: research

Transient left ventricular dysfunction during fever-induced Brugada-like electrocardiographic pattern
(Source: Europace)
Source: Europace - October 19, 2016 Category: Cardiology Authors: Stankovic, I., Janicijevic, A., Neskovic, A. N. Tags: Case Reports Source Type: research

Slowed depolarization and irregular repolarization in catecholaminergic polymorphic ventricular tachycardia: a study from cellular Ca2+ transients and action potentials to clinical monophasic action potentials and electrocardiography
Aims Spontaneous Ca2+ release leads to afterdepolarizations and triggered arrhythmia in catecholaminergic polymorphic ventricular tachycardia (CPVT). Irregular Ca2+ release is hypothesized to manifest as slowed depolarization and irregular repolarization. Our goal was to study depolarization and repolarization abnormalities in CPVT, as they remain largely uninvestigated. Methods and results We studied intracellular Ca2+ handling and action potentials (APs) in an induced pluripotent stem cell (iPSC) model of CPVT. Induced pluripotent stem cell cardiomyocytes from a RyR2-P2328S patient showed increased non-alternating varia...
Source: Europace - October 19, 2016 Category: Cardiology Authors: Paavola, J., Väänänen, H., Larsson, K., Penttinen, K., Toivonen, L., Kontula, K., Laine, M., Aalto-Setälä, K., Swan, H., Viitasalo, M. Tags: Basic Science Source Type: research

Early repolarization pattern: a marker of increased risk in patients with catecholaminergic polymorphic ventricular tachycardia
Conclusion A pathologic ERP is present in an unexpected large proportion (45%) of patients and is associated with an increased frequency of syncope. In patients with unexplained syncope and ERP at baseline, exercise testing should be performed to detect CPVT. (Source: Europace)
Source: Europace - October 19, 2016 Category: Cardiology Authors: Tülümen, E., Schulze-Bahr, E., Zumhagen, S., Stallmeyer, B., Seebohm, G., Beckmann, B.-M., Kääb, S., Rudic, B., Liebe, V., Wolpert, C., Herrera-Siklody, C., Veltmann, C., Schimpf, R., Borggrefe, M. Tags: Channelopathies Source Type: research

Feasibility and safety of transseptal puncture procedures for radiofrequency catheter ablation in small children weighing below 30 kg: single-centre experience
Aims Transseptal puncture (TSP) has become a common approach in catheter ablation of arrhythmia originating from the left atrium. In paediatric patients, however, TSP can be a challenge due to narrower access vessels and small left atrial size, and the safety of TSP in smaller children is yet to be understood. The purpose of this study was to retrospectively evaluate the feasibility and safety of TSP in children weighing below 30 kg. Methods and results Among 655 paediatric patients who underwent catheter ablation of arrhythmia between July 2009 and April 2015, 43 cases having structurally normal hearts, weighing
Source: Europace - October 19, 2016 Category: Cardiology Authors: Yoshida, S., Suzuki, T., Yoshida, Y., Watanabe, S., Nakamura, K., Sasaki, T., Kawasaki, Y., Ehara, E., Murakami, Y., Kato, T., Nakamura, Y. Tags: Cardiac electrophysiology Source Type: research

'Life-saving inappropriate ICD shock
(Source: Europace)
Source: Europace - October 19, 2016 Category: Cardiology Authors: Ferri-Certic, J. Tags: Case Reports Source Type: research

The circadian variation of premature atrial contractions
Aims The aim of the study was to assess a possible circadian variation of premature atrial contractions (PACs) in a community-based population and to determine if the daily variation could be used to assess a more vulnerable period of PACs in predicting later incidence of atrial fibrillation (AF). Methods and results We studied 638 subjects between the ages of 55 and 75 years from the Copenhagen Holter Study who underwent up to 48 h electrocardiogram recording. Follow-up on cardiovascular endpoints was performed in 2013 with a median follow-up time of 14.4 years. According to previous studies, two subgroups were studied b...
Source: Europace - October 19, 2016 Category: Cardiology Authors: Larsen, B. S., Kumarathurai, P., Nielsen, O. W., Sajadieh, A. Tags: Cardiac electrophysiology Source Type: research

Leadless cardiac pacemaker as alternative in case of congenital vascular abnormality and pocket infection
(Source: Europace)
Source: Europace - October 19, 2016 Category: Cardiology Authors: Garweg, C., Ector, J., Willems, R. Tags: Case Reports Source Type: research

Phrenic paralysis during cardiac electronic device implantation: incidence, causes and clinical course
Conclusions Transient phrenic paralysis may occur during CIED implantation probably related to the infiltration of local anaesthesia in the subclavian area. Mechanism, prevention, and management are discussed. (Source: Europace)
Source: Europace - October 19, 2016 Category: Cardiology Authors: Lopez-Gil, M., Fontenla, A., Julia, J., Parra, J. J., Arribas, F. Tags: Pacing and resynchronization therapy Source Type: research

Usefulness of 'figure-of-eight suture to achieve haemostasis after removal of 15-French calibre femoral venous sheath in patients undergoing cryoablation
Aims Among patients undergoing cryoballoon-based atrial fibrillation (AF) ablation, in order to reduce access site complications, improve staff efficiency, and decrease length of stay, various techniques have been implemented to achieve immediate haemostasis. We aimed to assess the efficacy and safety of ‘figure-of-eight (FoE)’ suture when compared with conventional manual compression for immediate closure of 15-French (Fr) calibre right femoral venous access after cryoablation. Methods and results A total of 200 patients (48% female, mean age 55 ± 12.4 years, and 77% paroxysmal AF) with symptomatic AF ...
Source: Europace - October 19, 2016 Category: Cardiology Authors: Aytemir, K., Canpolat, U., Yorgun, H., Evranos, B., Kaya, E. B., Sahiner, M. L., Özer, N. Tags: Ablation for atrial fibrillation Source Type: research

Thoracoscopic epicardial left atrial ablation in symptomatic patients with atrial fibrillation
Conclusion The total thoracoscopic surgical ablation procedure is highly effective even in patients with LPAF, and it seems safe. The high rate of iatrogenic LA re-entrant tachycardia, however, warrants further improvement of the technique. (Source: Europace)
Source: Europace - October 19, 2016 Category: Cardiology Authors: Probst, J., Jideus, L., Blomström, P., Zemgulis, V., Wassberg, E., Lönnerholm, S., Malmborg, H., Blomström Lundqvist, C. Tags: Ablation for atrial fibrillation Source Type: research

Collateral damage after endocardial catheter ablation
(Source: Europace)
Source: Europace - October 19, 2016 Category: Cardiology Authors: Vroomen, M., La Meir, M., Pison, L. Tags: Images In Electrophysiology Source Type: research

Omega-3 fatty acids do not alter P-wave parameters in electrocardiogram or expression of atrial connexins in patients undergoing coronary artery bypass surgery
Conclusions Omega-3 polyunsaturated fatty acids supplementation does not alter pro-arrhythmic P-wave parameters in ECG or connexin expression in human atrium with no effect on the incidence of AF following CABG surgery. (Source: Europace)
Source: Europace - October 19, 2016 Category: Cardiology Authors: Saravanan, P., West, A. L., Bridgewater, B., Davidson, N. C., Calder, P. C., Dobrzynsky, H., Trafford, A., O'Neill, S. C. Tags: Atrial fibrillation Source Type: research

Yield of screening for atrial fibrillation in primary care with a hand-held, single-lead electrocardiogram device during influenza vaccination
Conclusions Screening seems feasible with an easy to use single-lead, hand-held ECG device with automatic AF detection during influenza vaccination in primary care and results in a ‘1-day’ yield of 1.1% new cases of AF. Trial registration clinicaltrials.gov NCT02006524. (Source: Europace)
Source: Europace - October 19, 2016 Category: Cardiology Authors: Kaasenbrood, F., Hollander, M., Rutten, F. H., Gerhards, L. J., Hoes, A. W., Tieleman, R. G. Tags: Atrial fibrillation Source Type: research

Modelling projections for the uptake of edoxaban in an European population to 2050: effects on stroke, thromboembolism, and health economics perspectives
Conclusion Our data point to a substantial increase in the human and economic cost burden of AF and so emphasize the need to reduce this burden. This may be achieved by the increased use of oral anticoagulants, particularly with the NOACs such as edoxaban. (Source: Europace)
Source: Europace - October 19, 2016 Category: Cardiology Authors: Blann, A. D., Boriani, G., Lip, G. Y. H. Tags: Atrial fibrillation Source Type: research

Ventricular arrhythmia during ajmaline challenge for the Brugada syndrome
The Brugada syndrome is a genetic disease characterized by an abnormal electrocardiogram (ECG) and an elevated risk of sudden cardiac death. Sodium channel blockers (SCBs), such as ajmaline, are used to unmask the characteristic type 1 Brugada electrocardiographic pattern. We review the literature on the incidence of ventricular arrhythmia (VA) during SCB challenge. We evaluate the clinical and electrocardiographic characteristics of these patients as well as their prognosis. All articles published from January 2000 until August 2015, in which the incidence and predictors of VAs during SCB challenge were reported, are revi...
Source: Europace - October 19, 2016 Category: Cardiology Authors: Dobbels, B., De Cleen, D., Ector, J. Tags: Reviews Source Type: research

Imaging for assessment of sudden death risk: current role and future prospects
Sudden cardiac death (SCD) remains a major public health problem and there is an urgent need to maximize the impact of primary prevention using the implantable defibrillator. While implantable defibrillators are of utility for prevention of SCD, current methods of selecting candidates have significant shortcomings. Major advancements have occurred in the field of cardiac imaging, with significant potential to identify novel cardiac substrates for improved prediction. While assessment of the left ventricular ejection fraction remains the current major predictor, it is likely that several novel imaging markers will be incorp...
Source: Europace - October 19, 2016 Category: Cardiology Authors: Suzuki, T., Nazarian, S., Jerosch-Herold, M., Chugh, S. S. Tags: Reviews Source Type: research

The multiple proarrhythmic roles of cardiac calcium-handling abnormalities: triggered activity, conduction abnormalities, beat-to-beat variability, and adverse remodelling
(Source: Europace)
Source: Europace - October 19, 2016 Category: Cardiology Authors: Heijman, J., Schirmer, I., Dobrev, D. Tags: Editorials Source Type: research

Can screening for atrial fibrillation be implemented at scale?
(Source: Europace)
Source: Europace - October 19, 2016 Category: Cardiology Authors: Lowres, N., Neubeck, L., Freedman, S. B. Tags: Editorials Source Type: research

Ranolazine reduces atrial fibrillatory wave frequency
ConclusionRanolazine is associated with lower AF DF but no change in OI or fibrillatory wave amplitude. Prospective trials are needed to evaluate ranolazine's potential as a novel antiarrhythmic drug for AF. (Source: Europace)
Source: Europace - October 18, 2016 Category: Cardiology Source Type: research

Molecular autopsy of sudden unexplained deaths reveals genetic predispositions for cardiac diseases among young forensic cases
AbstractAimsCoronary artery disease accounts for the majority of sudden cardiac deaths (SCD) in the older population whereas cardiomyopathies and arrhythmogenic abnormalities predominate in younger SCD victims (
Source: Europace - October 17, 2016 Category: Cardiology Source Type: research

Ghostbusters should come back to lead extraction arena in order to fight with ghosts: Author's reply
We appreciate the interest of Dr Canpolat in our article.1,2 Persistence of residual fibrous tissue after transvenous lead extraction (TLE) has been described variously over the last few years.3–5 Focusing on pathophysiological mechanism for development of ‘ghost’, Andreaset al. described the histopathology of an inhomogeneous highly mobile structure in the right atrium after TLE, as organized thrombus in a case report.6 Immunohistochemical analysis of 17 extracted leads revealed that a fibrous capsule surrounding the lead was partially or completely covered with a monolayer of CD34 expressing endothelial...
Source: Europace - October 17, 2016 Category: Cardiology Source Type: research

Ghostbusters should come back to lead extraction arena in order to fight with ghosts
I was grateful to read an interesting paper by Narducciet al.1 which showed an association of the presence of ‘ghost’ after transvenous lead extraction (TLE) with Charlson co-morbidity index and intra-cardiac echocardiography (ICE) detected endocarditis. They also demonstrated that the occurrence of ‘ghost’ after TLE and systemic infection on admission were found as independent predictors of mortali ty at median 11 months follow-up. However, the pathophysiological mechanism for development of ‘ghost’ and its association with increased mortality were unclear. (Source: Europace)
Source: Europace - October 17, 2016 Category: Cardiology Source Type: research

‘… And now what to do?’ Direct surgical trans-atrial endocardial pacing electrode implantation in a very complex situation
(Source: Europace)
Source: Europace - October 17, 2016 Category: Cardiology Source Type: research

Clinical events preceding switching and discontinuation of oral anticoagulant treatment in patients with atrial fibrillation
ConclusionFor about one in five patients, treatment changes during anticoagulant therapy were preceded by a major clinical event. However, the majority of patients changed treatment for reasons not recorded in health registries. (Source: Europace)
Source: Europace - October 17, 2016 Category: Cardiology Source Type: research

Torsade de pointes arrhythmias arise at the site of maximal heterogeneity of repolarization in the chronic complete atrioventricular block dog
ConclusionChronic complete atrioventricular block dogs susceptible for TdP demonstrate higher RT differences. Torsade de pointes arises from a region with maximal heterogeneity of repolarization suggesting that a minimal gradient is required in order to initiate TdP. (Source: Europace)
Source: Europace - October 17, 2016 Category: Cardiology Source Type: research

Abrupt disruption of remote monitoring transmission as an indicator of safe backup mode
(Source: Europace)
Source: Europace - October 17, 2016 Category: Cardiology Source Type: research

Influence of energy source on early atrial fibrillation recurrences: a comparison of cryoballoon vs. radiofrequency current energy ablation with the endpoint of unexcitability in pulmonary vein isolation
AbstractIntroductionComparative data of early recurrence rates of atrial fibrillation (ERAF) following second-generation cryoballoon (CB-G2) and radiofrequency current (RFC) ablation for pulmonary vein isolation (PVI) in paroxysmal AF (PAF) are rare. We randomized PAF patients into either PVI with CB-G2 (group 1) or PVI with a combined RFC-approach applying contact force (CF) with the endpoint of unexcitability (group 2) to investigate ERAF.Methods and resultsIn group 1 (n = 30), CB-G2-PVI was performed. After CF-PVI in group 2 (n = 30), bipolar pacing on the ablation line and additional ablation until unexcitability was c...
Source: Europace - October 14, 2016 Category: Cardiology Source Type: research

Medium-term outcomes of idiopathic ventricular fibrillation survivors and family screening: a multicentre experience
ConclusionVentricular arrhythmia recurrence was lower than previously reported. Early repolarization was common in this IVF cohort, and horizontal ST segments were suggestive predictor for poorer outcomes. Persistent ER in proband was associated with ER in first-degree relatives. With better understanding of its predictive value and the relationship to IVF, this information could potentially be used to guide family screening and identify new mutations using family members with persistent ER. (Source: Europace)
Source: Europace - October 14, 2016 Category: Cardiology Source Type: research

Surgery for supraventricular tachycardia and congenital heart defects: long-term efficacy of the combined approach in adult patients
We present our long-term results with the surgical treatment of arrhythmias in adults with CHD (ACHD) undergoing elective cardiac surgery and the clinical predictors for arrhythmia recurrence.Methods and resultsBetween 2002 and 2013, 80 consecutive patients with CHD, mean age of 39 years, underwent intraoperative ablation with monopolar irrigated radiofrequency during cardiac surgery procedures. Significant clinical predictors of arrhythmia recurrence were determined by univariate analysis. We performed 47 right-sided Maze procedures, and 33 Cox-Maze III procedures. In 75 survivors, the ablation was effective immediately. ...
Source: Europace - October 14, 2016 Category: Cardiology Source Type: research

Clinically guided pacemaker choice and setting: pacemaker expert programming study
ConclusionsIn the present ‘real-world’ registry, a large number of patients (35.7%) did not receive an optimal PM for their rhythm disorders. Moreover, one-fourth of appropriate PMs were not programmed according to the patients’ clinical characteristics. (Source: Europace)
Source: Europace - October 14, 2016 Category: Cardiology Source Type: research