The role of ablation index-guided pulmonary vein isolation in high-sensitivity TrThe role of ablation index-guided pulmonary vein isolation in high-sensitivoponin I and atrial fibrillation recurrence
ConclusionsThese data suggest that AI-guided catheter ablation is associated with reduced levels of of Hs-cTnI and AEQ. Neither Hs-cTnI and AEQ should be used to predict arrhythmia recurrence. Abstract Figure. (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

Simultaneous orthogonal bipole mapping compared to conventional electrode configurations and impact on ablation strategies: results from a real world observational study
ConclusionThe HD grid catheter combined with simultaneous orthogonal bipole configuration can define myocardial substrate more accurately compared to standard along-the-spline configuration. The difference in substrate identification has potential impact on ablation strategy. Further clinical trials are needed to elucidate the role of orthogonal bipole configuration mapping and improved ablation success rates. (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

ECG wearable rhythm monitoring in covid-19 patients
ConclusionsUsing of wearable  electronic devices may contribute to better monitoring of the state of patients and control of symptoms. Abstract Figure. Hemodynamically significant rhythm pause (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

The pitfalls of unipolar voltage mapping of the right ventricle
Conclusion In the majority of endocardial and epicardial points the window-of-interest for unipolar voltage mapping needs to be adjusted to exclude far-field signal or ST-segment elevation/depression contributing to the automatically determined amplitude. Unadjusted unipolar voltage mapping underestimates low UV regions. RV-pacing generates a large unipolar far-field signal, which can obscure the local unipolar near-field signal. Accordingly, RV UV mapping during RV pacing should be used with caution. Abstract Figure. The pitfalls of UV mapping of the RV (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

Reducing clinical review burden for insertable cardiac monitors
ConclusionEGM prioritization rules for selecting up to 3 episodes/day significantly reduced EGM burden across all patients, not just "frequent fliers," with no delay-to-diagnosis in>97% of patients who exhibited a true arrhythmia. Implementing these rules on the patient care network may improve clinical workflow and ICM patient management. Abstract Figure. (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

Electrocardiographic markers of incident atrial fibrillation in patients with cryptogenic stroke
Conclusion: PWD and P-wave axis predicted incident AF in this subset of pts with cryptogenic stroke. The ECG may be a toll to identify pts at risk of developing AF, although larger studies are needed to confirm these results. Abstract Figure. (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

Sudden cardiac death due to ARVC in the young: molecular autopsy by whole exome sequencing of DNA from dried blood spots (DBS) collected at birth
ConclusionsDNA obtained from DBS has a quality comparable to that of blood and is a reliable source for WES-based molecular autopsy that may improve the diagnostic yield in cases of SCD. In a proportion of cases diagnosed post-mortem with ARVC, our molecular autopsy analysis pointed to a different diagnosis, highlighting its importance for the correct medical care of surviving relatives. (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

Single sweep pulmonary vein isolation using the endoscopic ablation system. Dream or reality?
ConclusionThe new X3 EAS equipped with a motor driven laser generator allows for single sweep PVI in 56% of PVs. Almost all PVs (94%) may be isolated with RAPID mode only leading to a very high first pass isolation rate. Altogether, this leads to substantially faster procedure times compared to the predecessor EAS. (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

Voltage bridge mapping in atrioventricular nodal reentry tachycardia ablation in adult population: results from a multicenter registry
ConclusionThe visualization of the Low Voltage Bridge may be a helpful tool to guide AVNRT ablation in a large cohort of pts; furthermore it is associated with reduced RF applications time. The KT characteristics are difficult to be predicted a priori according to patient gender, age or weight. (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

Sudden cardiac death risk stratification in patients with a preserved or mildly reduced ejection fraction: role of cardiac magnetic resonance and electrophysiological study
CONCLUSION Our preliminary results demonstrated that in patients with ischemic or non ischemic cardiopathy with preserved or mildly reduced EF, a positive MRI LGE pattern and the inducibility of ventricular arrhythmias during induction EPS identify a population at higher risk for clinical recurrence of ventr icular arryhthmic events. Further investigation is needed to validate this combined diagnostic strategy as new SCD prevention tool. (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

Impact of the COVID-19 pandemic on electrophysiological procedures at a national referral center
ConclusionsThe COVID-19 pandemic considerably affected the number of electrophysiological procedures in our center, reducing it by 33.4% compared to the previous years. The reduction of procedures fundamentally affected the electrophysiological studies and ablations, reducing them by 55.97%. The number of CIED related procedures were no affected. Electrophysiological procedures Procedures2017201820192017-2019 average2020CIED related procedures186148188174189Electrophysiological studies and ablations293263323293129Total479411511467319Comparative table of the electrophysiological procedures performed in our center in recent ...
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

A new electrocardiographic marker with higher sensitivity and specificity for epicardial location of posteroseptal accessory pathway
ConclusionThis study shows that an initially isoelectric or biphasic delta wave aspect in lead V1 has a higher specificity, sensitivity and positive predictive value than previously described ECG markers for epicardial location of posteroseptal accessory pathways. (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

Technical and electrophysiological aspects of multisite cardiac stimulation through the access of the middle cardiac vein
Conclusion: Multisite stimulation through the access of the middle cardiac vein proved to be a possible alternative, easy to perform and with a high PT index responsive to cardiac resynchronization therapy. (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

QT interval estimation in patients with right bundle branch block using validated formulas for left bundle branch block
CONCLUSIONSPreviously described formulas for LBBB exhibit marked differences regarding reliability in the estimation of QTc interval in the setting of RBBB. According to our results, Yankelson ’s method shows the most consistent agreement when estimating baseline QTc interval in patients with RBBB. Table 1.LBBB METHODFormula to estimate baseline QTcPearson’s R correlation coefficientCI (95%)Intraclass correlation coefficientCI (95%)YankelsonQTc - QRS + 95 (m) or 88 (f)0.805(0.632-0.97 7)0.882(0.788-0.934)Bogossian**QT - (QRS/2)0.813(0.644-0.982)0.756(-0.127-0.919)Wang**QT - (0.86*QRS - 71)0.801(0.627-0.974)0.834(0.465-...
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research

European early experience with a novel 3D mapping system
ConclusionsInitial European experience with this novel 3D mapping system included a wide variety of arrhythmias in the atria and ventricles. This new mapping system offered operators the flexibility to tailor to specific procedure needs with two imaging modalities which were both widely utilized. (Source: Europace)
Source: Europace - May 24, 2021 Category: Cardiology Source Type: research