New insights into the vitamin D/PTH axis in endocrine-driven metabolic bone diseases
ConclusionsAssessing the status of the vitamin D/PTH axis and using vitamin D and PTH as therapeutic agents is mandatory in several endocrine-related bone metabolic conditions. (Source: Endocrine)
Source: Endocrine - April 17, 2024 Category: Endocrinology Source Type: research
The health-related quality of life of patients with type 1 and type 2 diabetes mellitus: a meta-analysis
ConclusionOur results are sample-specific and cannot be generalized to all patients with DM. Therefore, more research is warranted on this topic. (Source: Endocrine)
Source: Endocrine - April 17, 2024 Category: Endocrinology Source Type: research
Reappraising the role of thyroid scintigraphy in the era of TIRADS: A clinically-oriented viewpoint
AbstractThyroid nodules (TNs) are a common entity, with the majority being benign. Therefore, employing an accurate rule-out strategy in clinical practice is essential. In the thyroid field, the current era is significantly marked by the worldwide diffusion of ultrasound (US)-based malignancy risk stratification systems of TN, usually reported as Thyroid Imaging Reporting And Data System (TIRADS). With the advent of US (and later TIRADS), the role of thyroid scintigraphy (TS) in clinical practice has gradually diminished. The authors of the present paper believe that the role of TS should be reappraised, also considering i...
Source: Endocrine - April 16, 2024 Category: Endocrinology Source Type: research
Neuroendocrine modulation by metamizole and indomethacin: investigating the impact on neuronal markers and GnRH release
ConclusionsThe results of our study showing an increase in the expression of neuronal factors reveal that metamizole and indomethacin may have possible neuroprotective effects. Moreover, the effects on the GnRH expression appear to be different. Animal models are required to confirm these effects of NSAIDs on neurons. (Source: Endocrine)
Source: Endocrine - April 16, 2024 Category: Endocrinology Source Type: research
Hypertension and diabetes, but not leptin and adiponectin, mediate the relationship between body fat and chronic kidney disease
ConclusionOur results suggest that the relations between BMI, TBF and CKD are in part mediated by diabetes and hypertension. (Source: Endocrine)
Source: Endocrine - April 16, 2024 Category: Endocrinology Source Type: research
Reappraising the role of thyroid scintigraphy in the era of TIRADS: A clinically-oriented viewpoint
AbstractThyroid nodules (TNs) are a common entity, with the majority being benign. Therefore, employing an accurate rule-out strategy in clinical practice is essential. In the thyroid field, the current era is significantly marked by the worldwide diffusion of ultrasound (US)-based malignancy risk stratification systems of TN, usually reported as Thyroid Imaging Reporting And Data System (TIRADS). With the advent of US (and later TIRADS), the role of thyroid scintigraphy (TS) in clinical practice has gradually diminished. The authors of the present paper believe that the role of TS should be reappraised, also considering i...
Source: Endocrine - April 16, 2024 Category: Endocrinology Source Type: research
Neuroendocrine modulation by metamizole and indomethacin: investigating the impact on neuronal markers and GnRH release
ConclusionsThe results of our study showing an increase in the expression of neuronal factors reveal that metamizole and indomethacin may have possible neuroprotective effects. Moreover, the effects on the GnRH expression appear to be different. Animal models are required to confirm these effects of NSAIDs on neurons. (Source: Endocrine)
Source: Endocrine - April 16, 2024 Category: Endocrinology Source Type: research
The survival after thyroidectomy versus lobectomy in multifocal papillary thyroid microcarcinoma patients
ConclusionsThyroidectomy was not associated with improved survival compared to thyroid lobectomy for patients with multifocal PTMC. (Source: Endocrine)
Source: Endocrine - April 15, 2024 Category: Endocrinology Source Type: research
Interventions to improve symptomatology in patients with hypothyroidism and persistent symptoms: A systematic review
ConclusionsThere is no high-quality evidence supporting any intervention for persistent symptoms in hypothyroidism. Available evidence, limited by the risk of bias, inconsistency, and heterogeneity, suggests that some persistent symptoms, particularly fatigue, could improve with ginger and thyroidectomy. (Source: Endocrine)
Source: Endocrine - April 15, 2024 Category: Endocrinology Source Type: research
Predictive value of postprandial C-peptide for utilizing multiple daily injection therapy in type 2 diabetes
ConclusionThe results of our study suggest that longer diabetes duration, higher FPG, and lower PCP were associated with necessity for MDI insulin regimen. These findings should assist with the personalization of insulin treatment. (Source: Endocrine)
Source: Endocrine - April 15, 2024 Category: Endocrinology Source Type: research
The survival after thyroidectomy versus lobectomy in multifocal papillary thyroid microcarcinoma patients
ConclusionsThyroidectomy was not associated with improved survival compared to thyroid lobectomy for patients with multifocal PTMC. (Source: Endocrine)
Source: Endocrine - April 15, 2024 Category: Endocrinology Source Type: research
Interventions to improve symptomatology in patients with hypothyroidism and persistent symptoms: A systematic review
ConclusionsThere is no high-quality evidence supporting any intervention for persistent symptoms in hypothyroidism. Available evidence, limited by the risk of bias, inconsistency, and heterogeneity, suggests that some persistent symptoms, particularly fatigue, could improve with ginger and thyroidectomy. (Source: Endocrine)
Source: Endocrine - April 15, 2024 Category: Endocrinology Source Type: research
Predictive value of postprandial C-peptide for utilizing multiple daily injection therapy in type 2 diabetes
ConclusionThe results of our study suggest that longer diabetes duration, higher FPG, and lower PCP were associated with necessity for MDI insulin regimen. These findings should assist with the personalization of insulin treatment. (Source: Endocrine)
Source: Endocrine - April 15, 2024 Category: Endocrinology Source Type: research
The effect of coping strategies on health –related quality of life in acromegaly patients
ConclusionOur results show that maladaptive coping styles have a substantial negative impact on psychological HRQoL in patients with acromegaly, whereas physical HRQoL is influenced to a lesser extent. Specialized training programs aimed at improving coping strategies could reduce long-term disease burden and increase HRQoL in the affected patients. (Source: Endocrine)
Source: Endocrine - April 13, 2024 Category: Endocrinology Source Type: research
