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Correction: Neuroendocrine disturbances in women with functional hypothalamic amenorrhea: an update and future directions
(Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research

Construction and validation of a nomogram for predicting lateral lymph node metastasis in pediatric and adolescent with differentiated thyroid carcinoma
ConclusionThe current investigation has effectively constructed a nomogram model utilizing visualized multipopulationsal data. Our findings demonstrate a significant association between various clinical characteristics and lateral LNM in pediatric and adolescent DTC patients. These outcomes hold substantial significance for healthcare practitioners, as they can employ this model to inform individualized clinical judgments for the pediatric and adolescent cohorts. (Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research

The relationship between advanced liver fibrosis and osteoporosis in type 2 diabetes patients with MAFLD
ConclusionThe BMD levels in male aged ≥50 years or postmenopausal female diabetic patients with MAFLD were negatively correlated with the degree of advanced liver fibrosis, which means an increased risk of liver fibrosis with decreasing BMD. (Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research

Association between phase angle and diabetic peripheral neuropathy in Type 2 diabetes patients
ConclusionsFor the first time, PhAs were acknowledged to be independently associated with DPN. Further exploration is needed to explain the findings. (Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research

Association of SGLT2is with respiratory and skin diseases
(Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research

Polymorphism rs5780218, rs12998 and rs10158616 in KISS1 gene among the Hubei province Chinese girls with the central precocious puberty
Conclusionsrs5780218 and rs12998 in theKISS1 gene may participate in genetic susceptibility to CPP in Chinese girls, and theKISS1 gene rs5780218 may serve as a genetic biomarker of CPP. However, the present findings should be validated in future studies with larger sample sizes in other ethnic populations. (Source: Endocrine)
Source: Endocrine - February 15, 2024 Category: Endocrinology Source Type: research

Effects of prediabetes and type 2 diabetes on cognitive functions
ConclusionT2DM causes early brain aging and declines cognitive functions since the prediabetic stage. Poor glycemic control in T2DM patients contributes to cognitive impairments, especially in learning. (Source: Endocrine)
Source: Endocrine - February 15, 2024 Category: Endocrinology Source Type: research

Risk stratification by combining common genetic mutations and TERT promoter methylation in papillary thyroid cancer
ConclusionsThis study suggested that comprehensively analysis ofBRAF/RAS mutations,TERT promoter mutation and methylation is an effective strategy to identify high-risk patients with PTC. (Source: Endocrine)
Source: Endocrine - February 14, 2024 Category: Endocrinology Source Type: research

Gonadal dysfunction in women with diabetes mellitus
AbstractIt is well known that both type 1 and type 2 diabetes mellitus (DM) are related to increased risk for cardiovascular (CV) and chronic kidney disease (CKD). However, besides these prominently presented complications, DM has also been associated with reproductive dysfunctions. It seems that these disorders are met in up to 40% of women with DM and consist of delayed menarche, all types of menstrual disorders, such as amenorrhea, oligomenorrhea, menstrual irregularity, as well as menorrhagia, infertility, characteristics of polycystic ovary syndrome (PCOS) and early (or rarely late) menopause. In type 1 DM (T1DM), ins...
Source: Endocrine - February 14, 2024 Category: Endocrinology Source Type: research

Multiple bronchial carcinoids associated with Cowden syndrome
We present a case of a 46-year-old male patient diagnosed with testicular seminoma and follicular thyroid cancer in his medical history. Our patient met the clinical diagnostic criteria of Cowden syndrome. Genetic analysis established the clinical diagnosis; a known heterozygousPTEN mutation was detected [PTEN (LRG_311t1)c.388 C > T (p.Arg130Ter)]. Incidentally, he was also seen with multiple pulmonary lesions during his oncological follow-up. A video-assisted thoracoscopic left lingula wedge resection and later resections from the right lung were performed. Histological findings revealed typical pulmonary carci...
Source: Endocrine - February 14, 2024 Category: Endocrinology Source Type: research