Liraglutide induced browning of visceral white adipose through regulation of miRNAs in high-fat-diet-induced obese mice
ConclusionOur findings suggest that liraglutide could promote brown remodeling of visceral WAT by bi-regulating miRNAs; this might be one of the mechanisms underlying its effect on weight loss. (Source: Endocrine)
Source: Endocrine - February 20, 2024 Category: Endocrinology Source Type: research
Increased oxidative stress is associated with hyperandrogenemia in polycystic ovary syndrome evidenced by oxidized lipoproteins stimulating rat ovarian androgen synthesis in vitro
ConclusionsOxidative stress can promote androgen production by up-regulating the expression of testosterone synthesis-related enzymes in vitro and may be an essential factor in elevating serum TT levels in patients with PCOS. (Source: Endocrine)
Source: Endocrine - February 19, 2024 Category: Endocrinology Source Type: research
Interobserver variability in thyroid ultrasound
ConclusionsInterobserver agreement was acceptable for the identification of nodules requiring cytologic study using various classification systems. However, limited concordance was observed in risk stratification and many ultrasonographic characteristics of the nodules. (Source: Endocrine)
Source: Endocrine - February 19, 2024 Category: Endocrinology Source Type: research
Are they functional hypogonadal men? Testosterone serum levels unravel male idiopathic infertility subgroups
ConclusionAlthough idiopathic infertile men show by definition altered semen analysis and gonadotropins within reference ranges, testosterone serum levels are widely variable in this population. Approximately a quarter of these patients present some sort of functional hypogonadism. Our data support the need to better classify idiopathic male infertility and total testosterone serum levels could be a supportive parameter in tracing the patient ’s therapeutic profile. (Source: Endocrine)
Source: Endocrine - February 19, 2024 Category: Endocrinology Source Type: research
Increased oxidative stress is associated with hyperandrogenemia in polycystic ovary syndrome evidenced by oxidized lipoproteins stimulating rat ovarian androgen synthesis in vitro
ConclusionsOxidative stress can promote androgen production by up-regulating the expression of testosterone synthesis-related enzymes in vitro and may be an essential factor in elevating serum TT levels in patients with PCOS. (Source: Endocrine)
Source: Endocrine - February 19, 2024 Category: Endocrinology Source Type: research
Interobserver variability in thyroid ultrasound
ConclusionsInterobserver agreement was acceptable for the identification of nodules requiring cytologic study using various classification systems. However, limited concordance was observed in risk stratification and many ultrasonographic characteristics of the nodules. (Source: Endocrine)
Source: Endocrine - February 19, 2024 Category: Endocrinology Source Type: research
Are they functional hypogonadal men? Testosterone serum levels unravel male idiopathic infertility subgroups
ConclusionAlthough idiopathic infertile men show by definition altered semen analysis and gonadotropins within reference ranges, testosterone serum levels are widely variable in this population. Approximately a quarter of these patients present some sort of functional hypogonadism. Our data support the need to better classify idiopathic male infertility and total testosterone serum levels could be a supportive parameter in tracing the patient ’s therapeutic profile. (Source: Endocrine)
Source: Endocrine - February 19, 2024 Category: Endocrinology Source Type: research
Construction and validation of a nomogram for predicting lateral lymph node metastasis in pediatric and adolescent with differentiated thyroid carcinoma
ConclusionThe current investigation has effectively constructed a nomogram model utilizing visualized multipopulationsal data. Our findings demonstrate a significant association between various clinical characteristics and lateral LNM in pediatric and adolescent DTC patients. These outcomes hold substantial significance for healthcare practitioners, as they can employ this model to inform individualized clinical judgments for the pediatric and adolescent cohorts. (Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research
The relationship between advanced liver fibrosis and osteoporosis in type 2 diabetes patients with MAFLD
ConclusionThe BMD levels in male aged ≥50 years or postmenopausal female diabetic patients with MAFLD were negatively correlated with the degree of advanced liver fibrosis, which means an increased risk of liver fibrosis with decreasing BMD. (Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research
Association between phase angle and diabetic peripheral neuropathy in Type 2 diabetes patients
ConclusionsFor the first time, PhAs were acknowledged to be independently associated with DPN. Further exploration is needed to explain the findings. (Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research
Association of SGLT2is with respiratory and skin diseases
(Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research
Correction: Neuroendocrine disturbances in women with functional hypothalamic amenorrhea: an update and future directions
(Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research
Construction and validation of a nomogram for predicting lateral lymph node metastasis in pediatric and adolescent with differentiated thyroid carcinoma
ConclusionThe current investigation has effectively constructed a nomogram model utilizing visualized multipopulationsal data. Our findings demonstrate a significant association between various clinical characteristics and lateral LNM in pediatric and adolescent DTC patients. These outcomes hold substantial significance for healthcare practitioners, as they can employ this model to inform individualized clinical judgments for the pediatric and adolescent cohorts. (Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research
The relationship between advanced liver fibrosis and osteoporosis in type 2 diabetes patients with MAFLD
ConclusionThe BMD levels in male aged ≥50 years or postmenopausal female diabetic patients with MAFLD were negatively correlated with the degree of advanced liver fibrosis, which means an increased risk of liver fibrosis with decreasing BMD. (Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research
Association between phase angle and diabetic peripheral neuropathy in Type 2 diabetes patients
ConclusionsFor the first time, PhAs were acknowledged to be independently associated with DPN. Further exploration is needed to explain the findings. (Source: Endocrine)
Source: Endocrine - February 17, 2024 Category: Endocrinology Source Type: research
