Current and Future Advances in Surgical Therapy for Pituitary Adenoma
Endocr Rev. 2023 May 19:bnad014. doi: 10.1210/endrev/bnad014. Online ahead of print.ABSTRACTThe vital physiological role of the pituitary gland, alongside its proximal critical neurovascular structures means pituitary adenomas cause significant morbidity or mortality. Whilst enormous advancements have been made in the surgical care of pituitary adenomas, treatment failure and recurrence remain challenges. To meet these clinical challenges, there has been an enormous expansion of novel medical technologies (e.g. endoscopy, advanced imaging, artificial intelligence). These innovations have the potential to benefit each step ...
Source: Endocrine Reviews - May 19, 2023 Category: Endocrinology Authors: Danyal Z Khan John G Hanrahan Stephanie E Baldeweg Neil L Dorward Danail Stoyanov Hani J Marcus Source Type: research

Medullary Thyroid Cancer- Updates and Challenges
Endocr Rev. 2023 May 19:bnad013. doi: 10.1210/endrev/bnad013. Online ahead of print.ABSTRACTA personalised approach to the management of Medullary Thyroid Cancer (MTC) presents several challenges, however in the past decade significant progress has been made in both diagnostic and treatment modalities. Germline RET testing in MEN 2 & 3, and somatic RET testing in sporadic MTC have revolutionized the treatment options available to patients. PET imaging with novel radioligands has improved characterization of disease and a new international grading system can predict prognosis. Systemic therapy for persistent and metasta...
Source: Endocrine Reviews - May 19, 2023 Category: Endocrinology Authors: Matti L Gild Roderick J Clifton-Bligh Lori J Wirth Bruce G Robinson Source Type: research

Current and Future Advances in Surgical Therapy for Pituitary Adenoma
Endocr Rev. 2023 May 19:bnad014. doi: 10.1210/endrev/bnad014. Online ahead of print.ABSTRACTThe vital physiological role of the pituitary gland, alongside its proximal critical neurovascular structures means pituitary adenomas cause significant morbidity or mortality. Whilst enormous advancements have been made in the surgical care of pituitary adenomas, treatment failure and recurrence remain challenges. To meet these clinical challenges, there has been an enormous expansion of novel medical technologies (e.g. endoscopy, advanced imaging, artificial intelligence). These innovations have the potential to benefit each step ...
Source: Endocrine Reviews - May 19, 2023 Category: Endocrinology Authors: Danyal Z Khan John G Hanrahan Stephanie E Baldeweg Neil L Dorward Danail Stoyanov Hani J Marcus Source Type: research

Medullary Thyroid Cancer- Updates and Challenges
Endocr Rev. 2023 May 19:bnad013. doi: 10.1210/endrev/bnad013. Online ahead of print.ABSTRACTA personalised approach to the management of Medullary Thyroid Cancer (MTC) presents several challenges, however in the past decade significant progress has been made in both diagnostic and treatment modalities. Germline RET testing in MEN 2 & 3, and somatic RET testing in sporadic MTC have revolutionized the treatment options available to patients. PET imaging with novel radioligands has improved characterization of disease and a new international grading system can predict prognosis. Systemic therapy for persistent and metasta...
Source: Endocrine Reviews - May 19, 2023 Category: Endocrinology Authors: Matti L Gild Roderick J Clifton-Bligh Lori J Wirth Bruce G Robinson Source Type: research

Current and Future Advances in Surgical Therapy for Pituitary Adenoma
Endocr Rev. 2023 May 19:bnad014. doi: 10.1210/endrev/bnad014. Online ahead of print.ABSTRACTThe vital physiological role of the pituitary gland, alongside its proximal critical neurovascular structures means pituitary adenomas cause significant morbidity or mortality. Whilst enormous advancements have been made in the surgical care of pituitary adenomas, treatment failure and recurrence remain challenges. To meet these clinical challenges, there has been an enormous expansion of novel medical technologies (e.g. endoscopy, advanced imaging, artificial intelligence). These innovations have the potential to benefit each step ...
Source: Endocrine Reviews - May 19, 2023 Category: Endocrinology Authors: Danyal Z Khan John G Hanrahan Stephanie E Baldeweg Neil L Dorward Danail Stoyanov Hani J Marcus Source Type: research

Medullary Thyroid Cancer- Updates and Challenges
Endocr Rev. 2023 May 19:bnad013. doi: 10.1210/endrev/bnad013. Online ahead of print.ABSTRACTA personalised approach to the management of Medullary Thyroid Cancer (MTC) presents several challenges, however in the past decade significant progress has been made in both diagnostic and treatment modalities. Germline RET testing in MEN 2 & 3, and somatic RET testing in sporadic MTC have revolutionized the treatment options available to patients. PET imaging with novel radioligands has improved characterization of disease and a new international grading system can predict prognosis. Systemic therapy for persistent and metasta...
Source: Endocrine Reviews - May 19, 2023 Category: Endocrinology Authors: Matti L Gild Roderick J Clifton-Bligh Lori J Wirth Bruce G Robinson Source Type: research

Current and Future Advances in Surgical Therapy for Pituitary Adenoma
Endocr Rev. 2023 May 19:bnad014. doi: 10.1210/endrev/bnad014. Online ahead of print.ABSTRACTThe vital physiological role of the pituitary gland, alongside its proximal critical neurovascular structures means pituitary adenomas cause significant morbidity or mortality. Whilst enormous advancements have been made in the surgical care of pituitary adenomas, treatment failure and recurrence remain challenges. To meet these clinical challenges, there has been an enormous expansion of novel medical technologies (e.g. endoscopy, advanced imaging, artificial intelligence). These innovations have the potential to benefit each step ...
Source: Endocrine Reviews - May 19, 2023 Category: Endocrinology Authors: Danyal Z Khan John G Hanrahan Stephanie E Baldeweg Neil L Dorward Danail Stoyanov Hani J Marcus Source Type: research

Medullary Thyroid Cancer- Updates and Challenges
Endocr Rev. 2023 May 19:bnad013. doi: 10.1210/endrev/bnad013. Online ahead of print.ABSTRACTA personalised approach to the management of Medullary Thyroid Cancer (MTC) presents several challenges, however in the past decade significant progress has been made in both diagnostic and treatment modalities. Germline RET testing in MEN 2 & 3, and somatic RET testing in sporadic MTC have revolutionized the treatment options available to patients. PET imaging with novel radioligands has improved characterization of disease and a new international grading system can predict prognosis. Systemic therapy for persistent and metasta...
Source: Endocrine Reviews - May 19, 2023 Category: Endocrinology Authors: Matti L Gild Roderick J Clifton-Bligh Lori J Wirth Bruce G Robinson Source Type: research

Current and Future Advances in Surgical Therapy for Pituitary Adenoma
Endocr Rev. 2023 May 19:bnad014. doi: 10.1210/endrev/bnad014. Online ahead of print.ABSTRACTThe vital physiological role of the pituitary gland, alongside its proximal critical neurovascular structures means pituitary adenomas cause significant morbidity or mortality. Whilst enormous advancements have been made in the surgical care of pituitary adenomas, treatment failure and recurrence remain challenges. To meet these clinical challenges, there has been an enormous expansion of novel medical technologies (e.g. endoscopy, advanced imaging, artificial intelligence). These innovations have the potential to benefit each step ...
Source: Endocrine Reviews - May 19, 2023 Category: Endocrinology Authors: Danyal Z Khan John G Hanrahan Stephanie E Baldeweg Neil L Dorward Danail Stoyanov Hani J Marcus Source Type: research

AMPK and the Endocrine Control of Metabolism
Endocr Rev. 2023 Apr 28:bnad012. doi: 10.1210/endrev/bnad012. Online ahead of print.ABSTRACTComplex multi-cellular organisms require a coordinated response from multiple tissues to maintain whole-body homeostasis in the face of energetic stressors like fasting, cold and exercise. It is also essential that energy is stored efficiently with feeding and the chronic nutrient surplus that occurs with obesity. Mammals have adapted several endocrine signals that regulate metabolism in response to changes in nutrient availability and energy demand. These include hormones altered by fasting and refeeding including insulin, glucagon...
Source: Endocrine Reviews - April 28, 2023 Category: Endocrinology Authors: Logan K Townsend Gregory R Steinberg Source Type: research