Correction to: "The Basis for Weekly Insulin Therapy: Evolving Evidence With Insulin Icodec and Insulin Efsitora Alfa"
Endocr Rev. 2024 Mar 22:bnae012. doi: 10.1210/endrev/bnae012. Online ahead of print.NO ABSTRACTPMID:38518751 | DOI:10.1210/endrev/bnae012 (Source: Endocrine Reviews)
Source: Endocrine Reviews - March 22, 2024 Category: Endocrinology Source Type: research
Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine Dysfunction
Endocr Rev. 2024 Mar 19:bnae010. doi: 10.1210/endrev/bnae010. Online ahead of print.ABSTRACTMultiple changes occur in hormonal regulation with aging and across various endocrine organs. These changes are associated with multiple age-related disorders and diseases. A better understanding of responsible underling biological mechanisms could help in the management of multiple endocrine disorders over and above hormone replacement therapy (HRT). Cellular senescence is involved in multiple biological aging processes and pathologies common in elderly individuals. Cellular senescence, which occurs in many older individuals but al...
Source: Endocrine Reviews - March 19, 2024 Category: Endocrinology Authors: Masayoshi Suda Karl H Paul Utkarsh Tripathi Tohru Minamino Tamara Tchkonia James L Kirkland Source Type: research
Relative Energy Deficiency in sport (REDs): Endocrine manifestations, pathophysiology and treatments
Endocr Rev. 2024 Mar 15:bnae011. doi: 10.1210/endrev/bnae011. Online ahead of print.ABSTRACTResearch on lean, energy-deficient athletic and military cohorts has broadened the concept of the Female Athlete Triad into the Relative Energy Deficiency in Sport (REDs) syndrome. REDs represents a spectrum of abnormalities induced by low energy availability (LEA), which serves as the underlying cause of all symptoms described within the REDs concept, affecting exercising populations of either biological sex. Both short- and long-term LEA, in conjunction with other moderating factors, may produce a multitude of maladaptive changes ...
Source: Endocrine Reviews - March 15, 2024 Category: Endocrinology Authors: Angeliki M Angelidi Konstantinos Stefanakis Sharon H Chou Laura Valenzuela-Vallejo Konstantina Dipla Chrysoula Boutari Konstantinos Ntoskas Panagiotis Tokmakidis Alexander Kokkinos Dimitrios G Goulis Helen A Papadaki Christos S Mantzoros Source Type: research
The Search for the Causes of Common Hyperandrogenism, 1965 to circa 2015
Endocr Rev. 2024 Mar 8:bnae007. doi: 10.1210/endrev/bnae007. Online ahead of print.ABSTRACTFrom 1965-2015, immense strides were made into understanding the mechanisms underlying the common androgen excess disorders, premature adrenarche and polycystic ovary syndrome (PCOS). The author reviews the critical discoveries of this era from his perspective investigating these disorders, commencing with his early discoveries of the unique pattern of plasma androgens in premature adrenarche and the elevation of an index of the plasma free testosterone concentration in most hirsute women. The molecular genetic basis, though not the ...
Source: Endocrine Reviews - March 8, 2024 Category: Endocrinology Authors: Robert L Rosenfield Source Type: research
