Protective Factors and the Pathogenesis of Complications in Diabetes
Endocr Rev. 2023 Aug 28:bnad030. doi: 10.1210/endrev/bnad030. Online ahead of print.ABSTRACTChronic complications of diabetes are due to myriad disorders of numerous metabolic pathways, which are responsible for most of the morbidity and mortality associated with the disease. Traditionally, diabetes complications are divided into those of micro- and macrovascular origin. We suggest revising this antiquated classification into diabetes complications of vascular, parenchymal, and hybrid (both vascular and parenchymal) tissue origin, since the profile of diabetes complications ranges from those involving only vascular tissues...
Source: ENDOCR REV - August 28, 2023 Category: Endocrinology Authors: Marc Gregory Yu Daniel Gordin Jialin Fu Kyoungmin Park Qian Li George Liang King Source Type: research
Protective Factors and the Pathogenesis of Complications in Diabetes
Endocr Rev. 2023 Aug 28:bnad030. doi: 10.1210/endrev/bnad030. Online ahead of print.ABSTRACTChronic complications of diabetes are due to myriad disorders of numerous metabolic pathways, which are responsible for most of the morbidity and mortality associated with the disease. Traditionally, diabetes complications are divided into those of micro- and macrovascular origin. We suggest revising this antiquated classification into diabetes complications of vascular, parenchymal, and hybrid (both vascular and parenchymal) tissue origin, since the profile of diabetes complications ranges from those involving only vascular tissues...
Source: ENDOCR REV - August 28, 2023 Category: Endocrinology Authors: Marc Gregory Yu Daniel Gordin Jialin Fu Kyoungmin Park Qian Li George Liang King Source Type: research
Efficacy of antiresorptive agents in fibrous dysplasia and McCune Albright syndrome, a systematic review and meta-analysis
This study supports the overall efficacy of antiresorptive therapies in terms of reducing bone remodeling, improving bone density, and pain in FD.PMID:37632645 | DOI:10.1007/s11154-023-09832-2 (Source: ENDOCR REV)
Source: ENDOCR REV - August 26, 2023 Category: Endocrinology Authors: H élios Bertin Mahmoud S Moussa Svetlana Komarova Source Type: research
Efficacy of antiresorptive agents in fibrous dysplasia and McCune Albright syndrome, a systematic review and meta-analysis
This study supports the overall efficacy of antiresorptive therapies in terms of reducing bone remodeling, improving bone density, and pain in FD.PMID:37632645 | DOI:10.1007/s11154-023-09832-2 (Source: ENDOCR REV)
Source: ENDOCR REV - August 26, 2023 Category: Endocrinology Authors: H élios Bertin Mahmoud S Moussa Svetlana Komarova Source Type: research
Metformin, cognitive function, and changes in the gut microbiome
Endocr Rev. 2023 Aug 21:bnad029. doi: 10.1210/endrev/bnad029. Online ahead of print.ABSTRACTThe decline in cognitive function and the prevalence of neurodegenerative disorders are among the most serious threats to health in old age. The prevalence of dementia has reached 50 million people worldwide and has become one of the major public health problems. The causes of age-related cognitive impairment are multiple, complex, and difficult to determine. However, type 2 diabetes (T2D) is linked to an enhanced risk of cognitive impairment and dementia. Human studies have shown that patients with T2D exhibit dysbiosis of the gut ...
Source: ENDOCR REV - August 21, 2023 Category: Endocrinology Authors: Marisel Rosell-D íaz Jos é Manuel Fernández-Real Source Type: research
Metformin, cognitive function, and changes in the gut microbiome
Endocr Rev. 2023 Aug 21:bnad029. doi: 10.1210/endrev/bnad029. Online ahead of print.ABSTRACTThe decline in cognitive function and the prevalence of neurodegenerative disorders are among the most serious threats to health in old age. The prevalence of dementia has reached 50 million people worldwide and has become one of the major public health problems. The causes of age-related cognitive impairment are multiple, complex, and difficult to determine. However, type 2 diabetes (T2D) is linked to an enhanced risk of cognitive impairment and dementia. Human studies have shown that patients with T2D exhibit dysbiosis of the gut ...
Source: ENDOCR REV - August 21, 2023 Category: Endocrinology Authors: Marisel Rosell-D íaz Jos é Manuel Fernández-Real Source Type: research
Metformin, cognitive function, and changes in the gut microbiome
Endocr Rev. 2023 Aug 21:bnad029. doi: 10.1210/endrev/bnad029. Online ahead of print.ABSTRACTThe decline in cognitive function and the prevalence of neurodegenerative disorders are among the most serious threats to health in old age. The prevalence of dementia has reached 50 million people worldwide and has become one of the major public health problems. The causes of age-related cognitive impairment are multiple, complex, and difficult to determine. However, type 2 diabetes (T2D) is linked to an enhanced risk of cognitive impairment and dementia. Human studies have shown that patients with T2D exhibit dysbiosis of the gut ...
Source: ENDOCR REV - August 21, 2023 Category: Endocrinology Authors: Marisel Rosell-D íaz Jos é Manuel Fernández-Real Source Type: research
Metformin, cognitive function, and changes in the gut microbiome
Endocr Rev. 2023 Aug 21:bnad029. doi: 10.1210/endrev/bnad029. Online ahead of print.ABSTRACTThe decline in cognitive function and the prevalence of neurodegenerative disorders are among the most serious threats to health in old age. The prevalence of dementia has reached 50 million people worldwide and has become one of the major public health problems. The causes of age-related cognitive impairment are multiple, complex, and difficult to determine. However, type 2 diabetes (T2D) is linked to an enhanced risk of cognitive impairment and dementia. Human studies have shown that patients with T2D exhibit dysbiosis of the gut ...
Source: ENDOCR REV - August 21, 2023 Category: Endocrinology Authors: Marisel Rosell-D íaz Jos é Manuel Fernández-Real Source Type: research
Metformin, cognitive function, and changes in the gut microbiome
Endocr Rev. 2023 Aug 21:bnad029. doi: 10.1210/endrev/bnad029. Online ahead of print.ABSTRACTThe decline in cognitive function and the prevalence of neurodegenerative disorders are among the most serious threats to health in old age. The prevalence of dementia has reached 50 million people worldwide and has become one of the major public health problems. The causes of age-related cognitive impairment are multiple, complex, and difficult to determine. However, type 2 diabetes (T2D) is linked to an enhanced risk of cognitive impairment and dementia. Human studies have shown that patients with T2D exhibit dysbiosis of the gut ...
Source: ENDOCR REV - August 21, 2023 Category: Endocrinology Authors: Marisel Rosell-D íaz Jos é Manuel Fernández-Real Source Type: research
Metabolic phenotyping in people living with obesity: Implications for dietary prevention
Rev Endocr Metab Disord. 2023 Aug 15. doi: 10.1007/s11154-023-09830-4. Online ahead of print.ABSTRACTGiven the increasing number of people living with obesity and related chronic metabolic disease, precision nutrition approaches are required to increase the effectiveness of prevention strategies. This review addresses these approaches in different metabolic phenotypes (metabotypes) in obesity. Although obesity is typically associated with an increased cardiometabolic disease risk, some people with obesity are relatively protected against the detrimental effects of excess adiposity on cardiometabolic health, also referred t...
Source: ENDOCR REV - August 15, 2023 Category: Endocrinology Authors: Ellen E Blaak Gijs H Goossens Source Type: research
Metabolic phenotyping in people living with obesity: Implications for dietary prevention
Rev Endocr Metab Disord. 2023 Aug 15. doi: 10.1007/s11154-023-09830-4. Online ahead of print.ABSTRACTGiven the increasing number of people living with obesity and related chronic metabolic disease, precision nutrition approaches are required to increase the effectiveness of prevention strategies. This review addresses these approaches in different metabolic phenotypes (metabotypes) in obesity. Although obesity is typically associated with an increased cardiometabolic disease risk, some people with obesity are relatively protected against the detrimental effects of excess adiposity on cardiometabolic health, also referred t...
Source: ENDOCR REV - August 15, 2023 Category: Endocrinology Authors: Ellen E Blaak Gijs H Goossens Source Type: research
Metabolic phenotyping in people living with obesity: Implications for dietary prevention
Rev Endocr Metab Disord. 2023 Aug 15. doi: 10.1007/s11154-023-09830-4. Online ahead of print.ABSTRACTGiven the increasing number of people living with obesity and related chronic metabolic disease, precision nutrition approaches are required to increase the effectiveness of prevention strategies. This review addresses these approaches in different metabolic phenotypes (metabotypes) in obesity. Although obesity is typically associated with an increased cardiometabolic disease risk, some people with obesity are relatively protected against the detrimental effects of excess adiposity on cardiometabolic health, also referred t...
Source: ENDOCR REV - August 15, 2023 Category: Endocrinology Authors: Ellen E Blaak Gijs H Goossens Source Type: research
Metabolic phenotyping in people living with obesity: Implications for dietary prevention
Rev Endocr Metab Disord. 2023 Aug 15. doi: 10.1007/s11154-023-09830-4. Online ahead of print.ABSTRACTGiven the increasing number of people living with obesity and related chronic metabolic disease, precision nutrition approaches are required to increase the effectiveness of prevention strategies. This review addresses these approaches in different metabolic phenotypes (metabotypes) in obesity. Although obesity is typically associated with an increased cardiometabolic disease risk, some people with obesity are relatively protected against the detrimental effects of excess adiposity on cardiometabolic health, also referred t...
Source: ENDOCR REV - August 15, 2023 Category: Endocrinology Authors: Ellen E Blaak Gijs H Goossens Source Type: research
Metabolic phenotyping in people living with obesity: Implications for dietary prevention
Rev Endocr Metab Disord. 2023 Aug 15. doi: 10.1007/s11154-023-09830-4. Online ahead of print.ABSTRACTGiven the increasing number of people living with obesity and related chronic metabolic disease, precision nutrition approaches are required to increase the effectiveness of prevention strategies. This review addresses these approaches in different metabolic phenotypes (metabotypes) in obesity. Although obesity is typically associated with an increased cardiometabolic disease risk, some people with obesity are relatively protected against the detrimental effects of excess adiposity on cardiometabolic health, also referred t...
Source: ENDOCR REV - August 15, 2023 Category: Endocrinology Authors: Ellen E Blaak Gijs H Goossens Source Type: research
Metabolic phenotyping in people living with obesity: Implications for dietary prevention
Rev Endocr Metab Disord. 2023 Aug 15. doi: 10.1007/s11154-023-09830-4. Online ahead of print.ABSTRACTGiven the increasing number of people living with obesity and related chronic metabolic disease, precision nutrition approaches are required to increase the effectiveness of prevention strategies. This review addresses these approaches in different metabolic phenotypes (metabotypes) in obesity. Although obesity is typically associated with an increased cardiometabolic disease risk, some people with obesity are relatively protected against the detrimental effects of excess adiposity on cardiometabolic health, also referred t...
Source: ENDOCR REV - August 15, 2023 Category: Endocrinology Authors: Ellen E Blaak Gijs H Goossens Source Type: research
