Non-alcoholic fatty liver disease and gut microbial dysbiosis- underlying mechanisms and gut microbiota mediated treatment strategies
Rev Endocr Metab Disord. 2023 Oct 16. doi: 10.1007/s11154-023-09843-z. Online ahead of print.ABSTRACTNon-alcoholic fatty liver disease (NAFLD) is by far the most prevalent form of liver disease worldwide. It's also the leading cause of liver-related hospitalizations and deaths. Furthermore, there is a link between obesity and NAFLD risk. A projected 25% of the world's population grieves from NAFLD, making it the most common chronic liver disorder. Several factors, such as obesity, oxidative stress, and insulin resistance, typically accompany NAFLD. Weight loss, lipid-lowering agents, thiazolidinediones, and metformin help ...
Source: ENDOCR REV - October 15, 2023 Category: Endocrinology Authors: Muthukumaran Jayachandran Shen Qu Source Type: research
Non-alcoholic fatty liver disease and gut microbial dysbiosis- underlying mechanisms and gut microbiota mediated treatment strategies
Rev Endocr Metab Disord. 2023 Oct 16. doi: 10.1007/s11154-023-09843-z. Online ahead of print.ABSTRACTNon-alcoholic fatty liver disease (NAFLD) is by far the most prevalent form of liver disease worldwide. It's also the leading cause of liver-related hospitalizations and deaths. Furthermore, there is a link between obesity and NAFLD risk. A projected 25% of the world's population grieves from NAFLD, making it the most common chronic liver disorder. Several factors, such as obesity, oxidative stress, and insulin resistance, typically accompany NAFLD. Weight loss, lipid-lowering agents, thiazolidinediones, and metformin help ...
Source: ENDOCR REV - October 15, 2023 Category: Endocrinology Authors: Muthukumaran Jayachandran Shen Qu Source Type: research
Non-alcoholic fatty liver disease and gut microbial dysbiosis- underlying mechanisms and gut microbiota mediated treatment strategies
Rev Endocr Metab Disord. 2023 Oct 16. doi: 10.1007/s11154-023-09843-z. Online ahead of print.ABSTRACTNon-alcoholic fatty liver disease (NAFLD) is by far the most prevalent form of liver disease worldwide. It's also the leading cause of liver-related hospitalizations and deaths. Furthermore, there is a link between obesity and NAFLD risk. A projected 25% of the world's population grieves from NAFLD, making it the most common chronic liver disorder. Several factors, such as obesity, oxidative stress, and insulin resistance, typically accompany NAFLD. Weight loss, lipid-lowering agents, thiazolidinediones, and metformin help ...
Source: ENDOCR REV - October 15, 2023 Category: Endocrinology Authors: Muthukumaran Jayachandran Shen Qu Source Type: research
Thirty years of active surveillance for low-risk thyroid cancer, lessons learned and future directions
Rev Endocr Metab Disord. 2023 Oct 14. doi: 10.1007/s11154-023-09844-y. Online ahead of print.ABSTRACTActive Surveillance is a non-invasive strategy designed to identify a minority of patients with low-risk papillary thyroid carcinoma who might experience clinical progression and benefit from additional definitive treatments. Global experience suggests that these tumors typically show minimal changes in size during active surveillance, often demonstrating very slow growth or even size reduction. Moreover, the rate of lymph node metastases is low and can be effectively managed through rescue surgery, without impacting cancer...
Source: ENDOCR REV - October 13, 2023 Category: Endocrinology Authors: Anabella Smulever Fabian Pitoia Source Type: research
Thirty years of active surveillance for low-risk thyroid cancer, lessons learned and future directions
Rev Endocr Metab Disord. 2023 Oct 14. doi: 10.1007/s11154-023-09844-y. Online ahead of print.ABSTRACTActive Surveillance is a non-invasive strategy designed to identify a minority of patients with low-risk papillary thyroid carcinoma who might experience clinical progression and benefit from additional definitive treatments. Global experience suggests that these tumors typically show minimal changes in size during active surveillance, often demonstrating very slow growth or even size reduction. Moreover, the rate of lymph node metastases is low and can be effectively managed through rescue surgery, without impacting cancer...
Source: ENDOCR REV - October 13, 2023 Category: Endocrinology Authors: Anabella Smulever Fabian Pitoia Source Type: research
Thirty years of active surveillance for low-risk thyroid cancer, lessons learned and future directions
Rev Endocr Metab Disord. 2023 Oct 14. doi: 10.1007/s11154-023-09844-y. Online ahead of print.ABSTRACTActive Surveillance is a non-invasive strategy designed to identify a minority of patients with low-risk papillary thyroid carcinoma who might experience clinical progression and benefit from additional definitive treatments. Global experience suggests that these tumors typically show minimal changes in size during active surveillance, often demonstrating very slow growth or even size reduction. Moreover, the rate of lymph node metastases is low and can be effectively managed through rescue surgery, without impacting cancer...
Source: ENDOCR REV - October 13, 2023 Category: Endocrinology Authors: Anabella Smulever Fabian Pitoia Source Type: research
The relationship between thyroid and human-associated microbiota: A systematic review of reviews
Rev Endocr Metab Disord. 2023 Oct 12. doi: 10.1007/s11154-023-09839-9. Online ahead of print.ABSTRACTIn recent years, a growing number of studies have examined the relationship between thyroid pathophysiology and intestinal microbiota composition. The reciprocal influence between these two entities has been proven so extensive that some authors coined the term "gut-thyroid axis". However, since some papers reported conflicting results, several aspects of this correlation need to be clarified. This systematic review was conceived to achieve more robust information about: 1)the characteristics of gut microbiota composition i...
Source: ENDOCR REV - October 12, 2023 Category: Endocrinology Authors: Camilla Virili Ilaria Stramazzo Maria Flavia Bagaglini Anna Lucia Carretti Silvia Capriello Francesco Romanelli Pierpaolo Trimboli Marco Centanni Source Type: research
Preoperative systemic inflammatory markers as prognostic factors in differentiated thyroid cancer: a systematic review and meta-analysis
CONCLUSIONS: Our meta-analysis showed no association between NLR, PLR, LMR and DFS in DTC; however, more prospective data are needed to better define the association between inflammatory status and prognosis of DTC.PMID:37828383 | DOI:10.1007/s11154-023-09845-x (Source: ENDOCR REV)
Source: ENDOCR REV - October 12, 2023 Category: Endocrinology Authors: Elena Russo Mathilda Guizzardi Luca Canali Francesca Gaino Andrea Costantino Gherardo Mazziotti Andrea Lania Silvia Uccella Luca Di Tommaso Fabio Ferreli Luca Malvezzi Giuseppe Spriano Giuseppe Mercante Source Type: research
The relationship between thyroid and human-associated microbiota: A systematic review of reviews
Rev Endocr Metab Disord. 2023 Oct 12. doi: 10.1007/s11154-023-09839-9. Online ahead of print.ABSTRACTIn recent years, a growing number of studies have examined the relationship between thyroid pathophysiology and intestinal microbiota composition. The reciprocal influence between these two entities has been proven so extensive that some authors coined the term "gut-thyroid axis". However, since some papers reported conflicting results, several aspects of this correlation need to be clarified. This systematic review was conceived to achieve more robust information about: 1)the characteristics of gut microbiota composition i...
Source: ENDOCR REV - October 12, 2023 Category: Endocrinology Authors: Camilla Virili Ilaria Stramazzo Maria Flavia Bagaglini Anna Lucia Carretti Silvia Capriello Francesco Romanelli Pierpaolo Trimboli Marco Centanni Source Type: research
Preoperative systemic inflammatory markers as prognostic factors in differentiated thyroid cancer: a systematic review and meta-analysis
CONCLUSIONS: Our meta-analysis showed no association between NLR, PLR, LMR and DFS in DTC; however, more prospective data are needed to better define the association between inflammatory status and prognosis of DTC.PMID:37828383 | DOI:10.1007/s11154-023-09845-x (Source: ENDOCR REV)
Source: ENDOCR REV - October 12, 2023 Category: Endocrinology Authors: Elena Russo Mathilda Guizzardi Luca Canali Francesca Gaino Andrea Costantino Gherardo Mazziotti Andrea Lania Silvia Uccella Luca Di Tommaso Fabio Ferreli Luca Malvezzi Giuseppe Spriano Giuseppe Mercante Source Type: research
Exploring the role of the inflammasomes on prostate cancer: Interplay with obesity
Rev Endocr Metab Disord. 2023 Oct 11. doi: 10.1007/s11154-023-09838-w. Online ahead of print.ABSTRACTObesity is a weight-related disorder characterized by excessive adipose tissue growth and dysfunction which leads to the onset of a systemic chronic low-grade inflammatory state. Likewise, inflammation is considered a classic cancer hallmark affecting several steps of carcinogenesis and tumor progression. In this regard, novel molecular complexes termed inflammasomes have been identified which are able to react to a wide spectrum of insults, impacting several metabolic-related disorders, but their contribution to cancer bio...
Source: ENDOCR REV - October 11, 2023 Category: Endocrinology Authors: Jes ús M Pérez-Gómez Antonio J Montero-Hidalgo Antonio C Fuentes-Fayos Andr é Sarmento-Cabral Rocio Guzm án-Ruiz Mar ía M Malagón Aura D Herrera-Mart ínez Manuel D Gahete Ra úl M Luque Source Type: research
Exploring the role of the inflammasomes on prostate cancer: Interplay with obesity
Rev Endocr Metab Disord. 2023 Oct 11. doi: 10.1007/s11154-023-09838-w. Online ahead of print.ABSTRACTObesity is a weight-related disorder characterized by excessive adipose tissue growth and dysfunction which leads to the onset of a systemic chronic low-grade inflammatory state. Likewise, inflammation is considered a classic cancer hallmark affecting several steps of carcinogenesis and tumor progression. In this regard, novel molecular complexes termed inflammasomes have been identified which are able to react to a wide spectrum of insults, impacting several metabolic-related disorders, but their contribution to cancer bio...
Source: ENDOCR REV - October 11, 2023 Category: Endocrinology Authors: Jes ús M Pérez-Gómez Antonio J Montero-Hidalgo Antonio C Fuentes-Fayos Andr é Sarmento-Cabral Rocio Guzm án-Ruiz Mar ía M Malagón Aura D Herrera-Mart ínez Manuel D Gahete Ra úl M Luque Source Type: research
Does it work in childhood and adolescence? The predictive role of postoperative/preablative stimulated thyroglobulin levels in paediatric thyroid cancer. A systematic review of the literature
DISCUSSION: ptTg is a readily available and inexpensive parameter, bearing a strong prognostic power in identifying disease persistence, relapse, and the presence of metastases in children affected by DTC.PMID:37743443 | DOI:10.1007/s11154-023-09835-z (Source: ENDOCR REV)
Source: ENDOCR REV - September 24, 2023 Category: Endocrinology Authors: Arnoldo Piccardo Francesco Fiz Gianluca Bottoni Luca Foppiani Domenico Albano Francesco Bertagna Ugo Catrambone Federica Mariani Beatrice Sambucco Michela Massollo Giorgio Treglia Pierpaolo Trimboli Source Type: research
Does it work in childhood and adolescence? The predictive role of postoperative/preablative stimulated thyroglobulin levels in paediatric thyroid cancer. A systematic review of the literature
DISCUSSION: ptTg is a readily available and inexpensive parameter, bearing a strong prognostic power in identifying disease persistence, relapse, and the presence of metastases in children affected by DTC.PMID:37743443 | DOI:10.1007/s11154-023-09835-z (Source: ENDOCR REV)
Source: ENDOCR REV - September 24, 2023 Category: Endocrinology Authors: Arnoldo Piccardo Francesco Fiz Gianluca Bottoni Luca Foppiani Domenico Albano Francesco Bertagna Ugo Catrambone Federica Mariani Beatrice Sambucco Michela Massollo Giorgio Treglia Pierpaolo Trimboli Source Type: research
Does it work in childhood and adolescence? The predictive role of postoperative/preablative stimulated thyroglobulin levels in paediatric thyroid cancer. A systematic review of the literature
DISCUSSION: ptTg is a readily available and inexpensive parameter, bearing a strong prognostic power in identifying disease persistence, relapse, and the presence of metastases in children affected by DTC.PMID:37743443 | DOI:10.1007/s11154-023-09835-z (Source: ENDOCR REV)
Source: ENDOCR REV - September 24, 2023 Category: Endocrinology Authors: Arnoldo Piccardo Francesco Fiz Gianluca Bottoni Luca Foppiani Domenico Albano Francesco Bertagna Ugo Catrambone Federica Mariani Beatrice Sambucco Michela Massollo Giorgio Treglia Pierpaolo Trimboli Source Type: research
