Artificial intelligence for reduced dose 18F-FDG PET examinations: a real-world deployment through a standardized framework and business case assessment
To determine whether artificial intelligence (AI) processed PET/CT images of reduced by one-third of 18-F-FDG activity compared to the standard injected dose, were non-inferior to native scans and if so to ass... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 9, 2021 Category: Radiology Authors: Katia Katsari, Daniele Penna, Vincenzo Arena, Giulia Polverari, Annarita Ianniello, Domenico Italiano, Rolando Milani, Alessandro Roncacci, Rowland O. Illing and Ettore Pelosi Tags: Original research Source Type: research
Improved PET/MRI accuracy by use of static transmission source in empirically derived hardware attenuation correction
Accurate quantification of radioactivity, measured by an integrated positron emission tomography (PET) and magnetic resonance imaging (MRI) system, is still a challenge. One aspect of such a challenge is to co... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 8, 2021 Category: Radiology Authors: Adam Farag, R. Terry Thompson, Jonathan D. Thiessen, Frank S. Prato and Jean Th éberge Tags: Original research Source Type: research
Automated assessment of functional lung imaging with 68Ga-ventilation/perfusion PET/CT using iterative histogram analysis
Functional lung mapping from Ga68-ventilation/perfusion (V/Q) PET/CT, which has been shown to correlate with pulmonary function tests (PFTs), may be beneficial in a number of clinical applications where sparing r... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 7, 2021 Category: Radiology Authors: Lachlan McIntosh, Price Jackson, Nicholas Hardcastle, Mathias Bressel, Tomas Kron, Jason W. Callahan, Daniel Steinfort, Nicholas Bucknell, Michael S. Hofman and Shankar Siva Tags: Original research Source Type: research
Gamma camera characterization at high holmium-166 activity in liver radioembolization
High activities of holmium-166 (166Ho) –labeled microspheres are used for therapeutic radioembolization, ideally directly followed by SPECT imaging for dosimetry purposes. The resulting high-count rate potentially... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 2, 2021 Category: Radiology Authors: Martina Stella, Arthur J. A. T. Braat, Marnix G. E. H. Lam, Hugo W. A. M. de Jong and Rob van Rooij Tags: Original research Source Type: research
Impact of segmentation and discretization on radiomic features in 68Ga-DOTA-TOC PET/CT images of neuroendocrine tumor
To identify the impact of segmentation methods and intensity discretization on radiomic features (RFs) extraction from 68Ga-DOTA-TOC PET images in patients with neuroendocrine tumors. (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 27, 2021 Category: Radiology Authors: Virginia Liberini, Bruno De Santi, Osvaldo Rampado, Elena Gallio, Beatrice Dionisi, Francesco Ceci, Giulia Polverari, Philippe Thuillier, Filippo Molinari and D ésirée Deandreis Tags: Original research Source Type: research
Cross-validation study between the HRRT and the PET component of the SIGNA PET/MRI system with focus on neuroimaging
The Siemens high-resolution research tomograph (HRRT - a dedicated brain PET scanner) is to this day one of the highest resolution PET scanners; thus, it can serve as useful benchmark when evaluating performan... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 26, 2021 Category: Radiology Authors: Julia G. Mannheim, Ju-Chieh (Kevin) Cheng, Nasim Vafai, Elham Shahinfard, Carolyn English, Jessamyn McKenzie, Jing Zhang, Laura Barlow and Vesna Sossi Tags: Original research Source Type: research
Head-to-head comparison of a Si-photomultiplier-based and a conventional photomultiplier-based PET-CT system
A novel generation of PET scanners based on silicon (Si)-photomultiplier (PM) technology has recently been introduced. Concurrently, there has been development of new reconstruction methods aimed at increasing... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 25, 2021 Category: Radiology Authors: Jenny Oddstig, Gustav Brolin, Elin Tr ägårdh and David Minarik Tags: Original research Source Type: research
Standard MRI-based attenuation correction for PET/MRI phantoms: a novel concept using MRI-visible polymer
We present a PET/MRI phantom built from MRI-visible m... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 18, 2021 Category: Radiology Authors: Ivo Rausch, Alejandra Valladares, Lalith Kumar Shiyam Sundar, Thomas Beyer, Marcus Hacker, Martin Meyerspeer and Ewald Unger Tags: Original research Source Type: research
Quantitative imaging of bone remodeling in patients with a unicompartmental joint unloading knee implant (ATLAS Knee System) —effect of metal artifacts on a SPECT-CT-based quantification
SPECT-CT using radiolabeled phosphonates is considered a standard for assessing bone metabolism (e.g., in patients with osteoarthritis of knee joints). However, SPECT can be influenced by metal artifacts in CT... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 17, 2021 Category: Radiology Authors: Oliver S. Grosser, Marcus Klutzny, Heiko Wissel, Dennis Kupitz, Michael Finger, Simone Schenke, Jan Wuestemann, Christoph H. Lohmann, Christoph Hoeschen, Maciej Pech, Christian Staerke and Michael C. Kreissl Tags: Original research Source Type: research
Theranostic SPECT reconstruction for improved resolution: application to radionuclide therapy dosimetry
SPECT-derived dose estimates in tissues of diameter less than 3 × system resolution are subject to significant losses due to the limited spatial resolution of the gamma camera. Incorporating resolution modellin... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 17, 2021 Category: Radiology Authors: H. Marquis, D. Deidda, A. Gillman, K. P. Willowson, Y. Gholami, T. Hioki, E. Eslick, K. Thielemans and D. L. Bailey Tags: Original research Source Type: research
Evaluation of SUVlean consistency in FDG and PSMA PET/MR with Dixon-, James-, and Janma-based lean body mass correction
To systematically evaluate the consistency of various standardized uptake value (SUV) lean body mass (LBM) normalization methods in a clinical positron emission tomography/magnetic resonance imaging (PET/MR) s... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 17, 2021 Category: Radiology Authors: Jun Zhao, Qiaoyi Xue, Xing Chen, Zhiwen You, Zhe Wang, Jianmin Yuan, Hui Liu and Lingzhi Hu Tags: Original research Source Type: research
Comparing lesion detection efficacy and image quality across different PET system generations to optimize the iodine-124 PET protocol for recurrent thyroid cancer
In recurrent differentiated thyroid cancer patients, detectability in 124I PET is limited for lesions with low radioiodine uptake. We assess the improvements in lesion detectability and image quality between thre... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 15, 2021 Category: Radiology Authors: David Kersting, Walter Jentzen, Miriam Sraieb, Pedro Fragoso Costa, Maurizio Conti, Lale Umutlu, Gerald Antoch, Michael Nader, Ken Herrmann, Wolfgang Peter Fendler, Christoph Rischpler and Manuel Weber Tags: Original research Source Type: research
Can a penalized-likelihood estimation algorithm be used to reduce the injected dose or the acquisition time in 68Ga-DOTATATE PET/CT studies?
Image quality and quantitative accuracy of positron emission tomography (PET) depend on several factors such as uptake time, scanner characteristics and image reconstruction methods. Ordered subset expectation... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 12, 2021 Category: Radiology Authors: Alexandre Chicheportiche, Elinor Goshen, Jeremy Godefroy, Simona Grozinsky-Glasberg, Kira Oleinikov, Amichay Meirovitz, David J. Gross and Simona Ben-Haim Tags: Original research Source Type: research
A method for evaluation of patient-specific lean body mass from limited-coverage CT images and its application in PERCIST: comparison with predictive equation
Standardized uptake value (SUV) normalized by lean body mass ([LBM] SUL) is recommended as metric by PERCIST 1.0. The James predictive equation (PE) is a frequently used formula for LBM estimation, but may cau... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 8, 2021 Category: Radiology Authors: Jingjie Shang, Zhiqiang Tan, Yong Cheng, Yongjin Tang, Bin Guo, Jian Gong, Xueying Ling, Lu Wang and Hao Xu Tags: Original research Source Type: research
Use of population input functions for reduced scan duration whole-body Patlak 18F-FDG PET imaging
Whole-body Patlak images can be obtained from an acquisition of first 6 min of dynamic imaging over the heart to obtain the arterial input function (IF), followed by multiple whole-body sweeps up to 60 min pi.... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 5, 2021 Category: Radiology Authors: Joyce van Sluis, Maqsood Yaqub, Adrienne H. Brouwers, Rudi A. J. O. Dierckx, Walter Noordzij and Ronald Boellaard Tags: Short communication Source Type: research
