Quantitative validation of Monte Carlo SPECT simulation: application to a Mediso AnyScan GATE simulation
Monte Carlo (MC) simulations are used in nuclear medicine imaging as they provide unparalleled insight into processes that are not directly experimentally measurable, such as scatter and attenuation in an acqu... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 30, 2023 Category: Radiology Authors: Sophia Pells, David M. Cullen, Daniel Deidda, Ana M. Denis-Bacelar, Andrew Fenwick, Kelley M. Ferreira, David Hamilton, Warda Heetun, Peter Julyan, George Needham, Ben Pietras, Emlyn Price, James Scuffham, Jill Tipping and Andrew P. Robinson Tags: Original research Source Type: research

Abstracts of the Total Body PET 2022 conference
(Source: EJNMMI Physics)
Source: EJNMMI Physics - September 28, 2023 Category: Radiology Tags: Meeting Abstracts Source Type: research

Guided block matching and 4-D transform domain filter projection denoising method for dynamic PET image reconstruction
Dynamic PET is an essential tool in oncology due to its ability to visualize and quantify radiotracer uptake, which has the potential to improve imaging quality. However, image noise caused by a low photon cou... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 25, 2023 Category: Radiology Authors: Lin Xin, Weihai Zhuo, Haikuan Liu and Tianwu Xie Tags: Original research Source Type: research

Performance study of a 360 ° CZT camera for monitoring 177Lu-PSMA treatment
The aim of this study was to investigate the quantification performance of a 360 ° CZT camera for 177Lu-based treatment monitoring. (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 22, 2023 Category: Radiology Authors: Laure Vergnaud, Jean-No ël Badel, Anne-Laure Giraudet, David Kryza, Thomas Mognetti, Thomas Baudier, Hanan Rida, Arnaud Dieudonné and David Sarrut Tags: Original research Source Type: research

Clinical validation of an AI-based automatic quantification tool for lung lobes in SPECT/CT
Lung lobar ventilation and perfusion (V/Q) quantification is generally obtained by generating planar scintigraphy images and then imposing three equally sized regions of interest on the data of each lung. This... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 21, 2023 Category: Radiology Authors: Emilie Verrecchia-Ramos, Olivier Morel, Merwan Ginet, Paul Retif and Sinan Ben Mahmoud Tags: Original research Source Type: research

Gamma camera-specific reference standards for radioactive iodine uptake measurements
Current guidelines of the radioiodine uptake (RAIU) test allow the use of different equipment, isotopes, activity and region-of-interest (ROI). We evaluated presence and extent of these differences in clinical... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 13, 2023 Category: Radiology Authors: Jurgen E. M. Mourik, Mark Derks, Erik T. te Beek and Marc R. J. ten Broek Tags: Original research Source Type: research

Framing protocol optimization in oncological Patlak parametric imaging with uKinetics
Total-body PET imaging with ultra-high sensitivity makes high-temporal-resolution framing protocols possible for the first time, which allows to capture rapid tracer dynamic changes. However, whether protocols... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 12, 2023 Category: Radiology Authors: Qing Ye, Hao Zeng, Yizhang Zhao, Weiguang Zhang, Yun Dong, Wei Fan and Yihuan Lu Tags: Original research Source Type: research

A proper protocol for routine 18F-FDG uEXPLORER total-body PET/CT scans
Conventional clinical PET scanners typically have an axial field of view (AFOV) of 15 –30 cm, resulting in limited coverage and relatively low photon detection efficiency. Taking advantage of the development of... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 11, 2023 Category: Radiology Authors: Huiran Hu, Yanchao Huang, Hongyan Sun, Kemin Zhou, Li Jiang, Jinmei Zhong, Li Chen, Lijuan Wang, Yanjiang Han and Hubing Wu Tags: Original research Source Type: research

A review of PET attenuation correction methods for PET-MR
Despite being thirteen years since the installation of the first PET-MR system, the scanners constitute a very small proportion of the total hybrid PET systems installed. This is in stark contrast to the rapid... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 11, 2023 Category: Radiology Authors: Georgios Krokos, Jane MacKewn, Joel Dunn and Paul Marsden Tags: Review Source Type: research

Estimation of relative biological effectiveness of 225Ac compared to 177Lu during [225Ac]Ac-PSMA and [177Lu]Lu-PSMA radiopharmaceutical therapy using TOPAS/TOPAS-nBio/MEDRAS
Over recent years, [225Ac]Ac-PSMA and [177Lu]Lu-PSMA radiopharmaceutical therapy have evolved as a promising treatment option for advanced prostate cancer. Especially for alpha particle emitter treatments, there ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 11, 2023 Category: Radiology Authors: Mikhail Rumiantcev, Wei Bo Li, Simon Lindner, Grigory Liubchenko, Sandra Resch, Peter Bartenstein, Sibylle I. Ziegler, Guido B öning and Astrid Delker Tags: Original research Source Type: research

Individualisation of radiation protection recommendations for patients treated with [177Lu]Lu-DOTA-TATE
As for any other nuclear medicine treatment, patients treated with [177Lu]Lu-DOTA-TATE should be given some radiation protection recommendations after being discharged to limit the dose received by family members... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 4, 2023 Category: Radiology Authors: Teresa Monserrat Fuertes, Borja Santos Zorrozua, Emilia Rode ño Ortiz de Zarate, Miguel Ángel Peinado Montes, Carmen Vigil Díaz and Pablo Mínguez Gabiña Tags: Original research Source Type: research

Deep learning approximation of attenuation maps for myocardial perfusion SPECT with an IQ\(\varvec{\cdot {}}\)SPECT collimator
The use of CT images for attenuation correction of myocardial perfusion imaging with single photon emission computer tomography (SPECT) increases diagnostic confidence. However, acquiring a CT image registered... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 28, 2023 Category: Radiology Authors: Tamino Huxohl, Gopesh Patel, Reinhard Zabel and Wolfgang Burchert Tags: Original research Source Type: research

Predicting [177Lu]Lu-HA-DOTATATE kidney and tumor accumulation based on [68Ga]Ga-HA-DOTATATE diagnostic imaging using semi-physiological population pharmacokinetic modeling
In this study, the population ph... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 24, 2023 Category: Radiology Authors: Hinke Siebinga, Berlinda J. de Wit-van der Veen, Jos H. Beijnen, Marcel P. M. Stokkel, Thomas P. C. Dorlo, Alwin D. R. Huitema and Jeroen J. M. A. Hendrikx Tags: Original research Source Type: research

Imaging of 212Pb in mice with a clinical SPECT/CT
212Pb is a promising radionuclide for targeted alpha therapy. Here, the feasibility of visualising the tumour uptake and biodistribution of 212Pb-NG001 in mice with a clinical SPECT/CT scanner was investigated. (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 21, 2023 Category: Radiology Authors: Monika Kvassheim, Anna Julie Kj øl Tornes, Asta Juzeniene, Caroline Stokke and Mona-Elisabeth R. Revheim Tags: Short communication Source Type: research

A GATE simulation study for dosimetry in cancer cell and micrometastasis from the 225Ac decay chain
Radiopharmaceutical therapy (RPT) with alpha-emitting radionuclides has shown great promise in treating metastatic cancers. The successive emission of four alpha particles in the 225Ac decay chain leads to highly... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 1, 2023 Category: Radiology Authors: Helena Koniar, Cassandra Miller, Arman Rahmim, Paul Schaffer and Carlos Uribe Tags: Original research Source Type: research