Dose-reduced [18F]PSMA-1007 PET is feasible for functional imaging of the renal cortex
In Prostate-specific membrane antigen (PSMA) positron emission tomography with computed tomography (PET-CT), there is significant renal uptake. The standard in renal cortical functional imaging is scintigraphy... (Source: EJNMMI Physics)
Source: EJNMMI Physics - October 29, 2021 Category: Radiology Authors: Kristian Valind, Jonas J ögi, David Minarik, Gustav Brolin and Elin Trägårdh Tags: Original research Source Type: research

Dual energy window imaging for optimisation of P/V ratios in VP SPECT
Ventilation –perfusion single-photon emission computed tomography (VP SPECT) plays an important role in pulmonary embolism diagnosis. Rapid results may be obtained using same-day ventilation followed by perfusi... (Source: EJNMMI Physics)
Source: EJNMMI Physics - October 16, 2021 Category: Radiology Authors: A. G. G. Doruyter and J. L. Holness Tags: Original research Source Type: research

Quantitative Effect of Metal Artefact Reduction on CT-based attenuation correction in FDG PET/CT in patients with hip prosthesis
This study aimed to investigate the effect of Smart MAR on quantitative PET anal... (Source: EJNMMI Physics)
Source: EJNMMI Physics - October 9, 2021 Category: Radiology Authors: Maarten Haemels, Delphine Vandendriessche, Jeroen De Geeter, James Velghe, Maxence Vandekerckhove and Frank De Geeter Tags: Original research Source Type: research

Performance evaluation of a PET insert for preclinical MRI in stand-alone PET and simultaneous PET –MRI modes
This study aimed to evaluate the performance of a preclinical PET insert in three configurations: as a stand-alone unit outside the MRI bore, inside the bore of a cryogen-free 3T MRI and, finally, while perfor... (Source: EJNMMI Physics)
Source: EJNMMI Physics - October 9, 2021 Category: Radiology Authors: Gaelle Emvalomenos, Sofie Trajanovska, Binh T. T. Pham, Peter Doughty, Jerome Burnet, Isabelle Smith, Ruslan Garipov, Marie-Claude Gregoire, Nana Sunn, John McGrath and Steven R. Meikle Tags: Original research Source Type: research

Impacts of acquisition and reconstruction parameters on the absolute technetium quantification of the cadmium –zinc–telluride-based SPECT/CT system: a phantom study
The digital cadmium –zinc–telluride (CZT)-based SPECT system has many advantages, including better spatial and energy resolution. However, the impacts of different acquisition and reconstruction parameters on C... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 26, 2021 Category: Radiology Authors: Ruyi Zhang, Miao Wang, Yaqian Zhou, Shen Wang, Yiming Shen, Ning Li, Peng Wang, Jian Tan, Zhaowei Meng and Qiang Jia Tags: Original research Source Type: research

Individualised dosimetry and safety of SIRT for intrahepatic cholangiocarcinoma
The aim of this study was to investigate the safety and efficacy of selective internal radiation therapy (SIRT) with 90Y resin microspheres for the treatment of Intrahepatic Cholangiocarcinoma (ICC). A total of 2... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 14, 2021 Category: Radiology Authors: Kathy P. Willowson, Enid M. Eslick and Dale L. Bailey Tags: Original research Source Type: research

Data-driven gated PET/CT: implications for lesion segmentation and quantitation
Data-driven gating (DDG) can improve PET quantitation and alleviate many issues with patient motion. However, misregistration between DDG-PET and CT may occur due to the distinct temporal resolutions of PET an... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 28, 2021 Category: Radiology Authors: M. Allan Thomas and Tinsu Pan Tags: Original research Source Type: research

Multimodal phantoms for clinical PET/MRI
Phantoms are commonly used throughout medical imaging and medical physics for a multitude of applications, the designs of which vary between modalities and clinical or research requirements. Within positron em... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 26, 2021 Category: Radiology Authors: Eve Lennie, Charalampos Tsoumpas and Steven Sourbron Tags: Review Source Type: research

Simple model for estimation of absorbed dose by organs and tumors after PRRT from a single SPECT/CT study
Following each cycle of peptide receptor radionuclide therapy (PRRT), absorbed doses by tumors and normal organs are typically calculated from three quantitative single-photon emission computed tomography (SPE... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 26, 2021 Category: Radiology Authors: Alexandre Chicheportiche, Moshe Sason, Jeremy Godefroy, Yodphat Krausz, Mahmoud Zidan, Kira Oleinikov, Amichay Meirovitz, David J. Gross, Simona Grozinsky-Glasberg and Simona Ben-Haim Tags: Original research Source Type: research

Evaluation of Iodine-123 and Iodine-131 SPECT activity quantification: a Monte Carlo study
The quantitative accuracy of Nuclear Medicine images, acquired for both planar and SPECT studies, is influenced by the isotope-collimator combination as well as image corrections incorporated in the iterative ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 19, 2021 Category: Radiology Authors: Michaella Morphis, Johan A. van Staden, Hanlie du Raan and Michael Ljungberg Tags: Original research Source Type: research

Correction to: Variability in lutetium-177 SPECT quantification between different state-of-the-art SPECT/CT systems
(Source: EJNMMI Physics)
Source: EJNMMI Physics - August 18, 2021 Category: Radiology Authors: Steffie M. B. Peters, Sebastiaan L. Meyer Viol, Niels R. van der Werf, Nick de Jong, Floris H. P. van Velden, Antoi Meeuwis, Mark W. Konijnenberg, Martin Gotthardt, Hugo W. A. M. de Jong and Marcel Segbers Tags: Correction Source Type: research

Dosimetric impact of Ac-227 in accelerator-produced Ac-225 for alpha-emitter radiopharmaceutical therapy of patients with hematological malignancies: a pharmacokinetic modeling analysis
Actinium-225 is an alpha-particle emitter under investigation for use in radiopharmaceutical therapy. To address limited supply, accelerator-produced 225Ac has been recently made available. Accelerator-produced 2... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 18, 2021 Category: Radiology Authors: George Sgouros, Bin He, Nitya Ray, Dale L. Ludwig and Eric C. Frey Tags: Original research Source Type: research

Optimisation of CT protocols in PET-CT across different scanner models using different automatic exposure control methods and iterative reconstruction algorithms
A significant proportion of the radiation dose from a PET-CT examination is dependent on the CT protocol, which should be optimised for clinical purposes. Matching protocols on different scanners within an ima... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 31, 2021 Category: Radiology Authors: Sarah-May Gould, Jane Mackewn, Sugama Chicklore, Gary J. R. Cook, Andrew Mallia and Lucy Pike Tags: Original research Source Type: research

Optimization of SPECT/CT imaging protocols for quantitative and qualitative 99mTc SPECT
The introduction of hybrid SPECT/CT devices enables quantitative imaging in SPECT, providing a methodological setup for quantitation using SPECT tracers comparable to PET/CT. We evaluated a specific quantitati... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 30, 2021 Category: Radiology Authors: Dennis Kupitz, Heiko Wissel, Jan Wuestemann, Stephanie Bluemel, Maciej Pech, Holger Amthauer, Michael C. Kreissl and Oliver S. Grosser Tags: Original research Source Type: research

Yttrium-90 quantitative phantom study using digital photon counting PET
PET imaging of 90Y-microsphere distribution following radioembolisation is challenging due to the count-starved statistics from the low branching ratio of e+/e − pair production during 90Y decay. PET systems using... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 27, 2021 Category: Radiology Authors: Joey Labour, Philippe Boissard, Thomas Baudier, Fouzi Khayi, David Kryza, Pascale Veyrat Durebex, Sandrine Parisse-Di Martino, Thomas Mognetti, David Sarrut and Jean-No ël Badel Tags: Original research Source Type: research