Estimation of brain amyloid accumulation using deep learning in clinical [11C]PiB PET imaging
Estimation of brain amyloid accumulation is valuable for evaluation of patients with cognitive impairment in both research and clinical routine. The development of high throughput and accurate strategies for t... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 14, 2023 Category: Radiology Authors: Claes N øhr Ladefoged, Lasse Anderberg, Karine Madsen, Otto Mølby Henriksen, Steen Gregers Hasselbalch, Flemming Littrup Andersen, Liselotte Højgaard and Ian Law Tags: Original research Source Type: research
Collection on total-body PET
(Source: EJNMMI Physics)
Source: EJNMMI Physics - July 10, 2023 Category: Radiology Authors: Kuangyu Shi and Charalampos Tsoumpas Tags: Editorial Source Type: research
A machine learning-based model for a dose point kernel calculation
This study reports on the design, implementation, and test of a multi-target regressor approach to ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - June 26, 2023 Category: Radiology Authors: Ignacio Scarinci, Mauro Valente and Pedro P érez Tags: Original research Source Type: research
A list-mode multi-energy window low-count SPECT reconstruction method for isotopes with multiple emission peaks
(Source: EJNMMI Physics)
Source: EJNMMI Physics - June 22, 2023 Category: Radiology Authors: Md Ashequr Rahman, Zekun Li, Zitong Yu, Richard Laforest, Daniel L. J. Thorek and Abhinav K. Jha Tags: Original research Source Type: research
Tumor dosimetry using 177Lu: influence of background activity, measurement method and reconstruction algorithm
Image-based tumor dosimetry after radionuclide therapy, using the isotope 177Lu, finds application e.g., for tumor-to-organ dose comparison and for dose response evaluation. When the tumor extent is not much larg... (Source: EJNMMI Physics)
Source: EJNMMI Physics - June 21, 2023 Category: Radiology Authors: Peter Fr øhlich Staanum Tags: Original research Source Type: research
Variability in PET image quality and quantification measured with a permanently filled 68Ge-phantom: a multi-center study
This study evaluated, as a snapshot, the variability in quantification and image quality (IQ) of the clinically utilized PET [18F]FDG whole-body protocols in Finland using a NEMA/IEC IQ phantom permanently filled... (Source: EJNMMI Physics)
Source: EJNMMI Physics - June 16, 2023 Category: Radiology Authors: O. Sipil ä, J. Liukkonen, H.-L. Halme, T. Tolvanen, A. Sohlberg, M. Hakulinen, A.-L. Manninen, K. Tahvanainen, V. Tunninen, T. Ollikainen, T. Kangasmaa, A. Kangasmäki and J. Vuorela Tags: Original research Source Type: research
Monte Carlo simulation of the system performance of a long axial field-of-view PET based on monolithic LYSO detectors
In light of the milestones achieved in PET design so far, further sensitivity improvements aim to optimise factors such as the dose, throughput, and detection of small lesions. While several longer axial field... (Source: EJNMMI Physics)
Source: EJNMMI Physics - June 13, 2023 Category: Radiology Authors: Maya Abi-Akl, Meysam Dadgar, Yassine Toufique, Othmane Bouhali and Stefaan Vandenberghe Tags: Original research Source Type: research
Evaluation of reconstruction methods and image noise levels concerning visual assessment of simulated liver lesions in 111In-octreotide SPECT imaging
Early cancer detection is crucial for patients ’ survival. The image quality in 111In-octreotide SPECT imaging could be improved by using Monte Carlo (MC)-based reconstruction. The aim of this observational study ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - June 2, 2023 Category: Radiology Authors: Emma Wikberg, Martijn van Essen, Tobias Ryd én, Johanna Svensson, Peter Gjertsson and Peter Bernhardt Tags: Original research Source Type: research
Development of a bespoke phantom to optimize molecular PET imaging of pituitary tumors
Image optimization is a key step in clinical nuclear medicine, and phantoms play an essential role in this process. However, most phantoms do not accurately reflect the complexity of human anatomy, and this pr... (Source: EJNMMI Physics)
Source: EJNMMI Physics - June 1, 2023 Category: Radiology Authors: Daniel Gillett, Daniel Marsden, Rosy Crawford, Safia Ballout, James MacFarlane, Merel van der Meulen, Bethany Gillett, Nick Bird, Sarah Heard, Andrew S. Powlson, Thomas Santarius, Richard Mannion, Angelos Kolias, Ines Harper, Iosif A. Mendichovszky, Luigi Tags: Original research Source Type: research
NEMA NU 1-2018 performance characterization and Monte Carlo model validation of the Cubresa Spark SiPM-based preclinical SPECT scanner
The Cubresa Spark is a novel benchtop silicon-photomultiplier (SiPM)-based preclinical SPECT system. SiPMs in SPECT significantly improve resolution and reduce detector size compared to preclinical cameras wit... (Source: EJNMMI Physics)
Source: EJNMMI Physics - June 1, 2023 Category: Radiology Authors: Matthew E. Strugari, Drew R. DeBay, Steven D. Beyea and Kimberly D. Brewer Tags: Original research Source Type: research
Characterization of the partial volume effect along the axial field-of-view of the Biograph Vision Quadra total-body PET/CT system for multiple isotopes
Total-body PET scanners with axial field of views (FOVs) longer than 1 m enable new applications to study multiple organs (e.g., the brain-gut-axis) simultaneously. As the spatial resolution and the associated... (Source: EJNMMI Physics)
Source: EJNMMI Physics - May 27, 2023 Category: Radiology Authors: Julia G. Mannheim, Ivo Rausch, Maurizio Conti, Christian la Foug ère and Fabian P. Schmidt Tags: Original research Source Type: research
A systematic review and meta-analysis on the radiation dose of computed tomography in hybrid nuclear medicine imaging
While diagnostic reference levels (DRLs) are well-established for the radiopharmaceutical part, published DRLs for the CT component of positron emission tomography/computed tomography (PET/CT) and single photo... (Source: EJNMMI Physics)
Source: EJNMMI Physics - May 25, 2023 Category: Radiology Authors: Gwenny Verfaillie, Caro Franck, An De Crop, Laurence Beels, Yves D ’Asseler and Klaus Bacher Tags: Review Source Type: research
Safety injections of nuclear medicine radiotracers: towards a new modality for a real-time detection of extravasation events and 18F-FDG SUV data correction
18F-FDG PET/CT imaging allows to study oncological patients and their relative diagnosis through the standardised uptake value (SUV) evaluation. During radiopharmaceutical injection, an extravasation event may o.... (Source: EJNMMI Physics)
Source: EJNMMI Physics - May 23, 2023 Category: Radiology Authors: Mauro Iori, Elisa Grassi, Lorenzo Piergallini, Greta Meglioli, Andrea Botti, Giada Sceni, Noemi Cucurachi, Laura Verzellesi, Domenico Finocchiaro, Annibale Versari, Beatrice Fraboni and Federica Fioroni Tags: Original research Source Type: research
Triple modality image reconstruction of PET data using SPECT, PET, CT information increases lesion uptake in images of patients treated with radioembolization with \(^{90}Y\) micro-spheres
Nuclear medicine imaging modalities like computed tomography (CT), single photon emission CT (SPECT) and positron emission tomography (PET) are employed in the field of theranostics to estimate and plan the do... (Source: EJNMMI Physics)
Source: EJNMMI Physics - May 3, 2023 Category: Radiology Authors: Daniel Deidda, Ana M. Denis-Bacelar, Andrew J. Fenwick, Kelley M. Ferreira, Warda Heetun, Brian F. Hutton, Daniel R. McGowan, Andrew P. Robinson, James Scuffham, Kris Thielemans and Robert Twyman Tags: Original research Source Type: research
Quantitative application of dual-phase 99mTc-sestamibi SPECT/CT imaging of parathyroid lesions: identification of optimal timing in secondary hyperparathyroidism
In this retrospective study, we compared the maximum standardized uptake values (SUVmax) of parathyroid lesions and the target-to-background ratio (TBR) of parathyroid lesions to thyroid tissue in early-phase ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - April 20, 2023 Category: Radiology Authors: Yuhua Wang, Ye Liu, Na Li, Kang Xu and Wanchun Zhang Tags: Original research Source Type: research
