177Lu-DOTA-0-Tyr3-octreotate infusion modeling for real-time detection and characterization of extravasation during PRRT
Given the recent and rapid development of peptide receptor radionuclide therapy (PRRT), increasing emphasis should be placed on the early identification and quantification of therapeutic radiopharmaceutical (t... (Source: EJNMMI Physics)
Source: EJNMMI Physics - May 3, 2022 Category: Radiology Authors: Christophe Mazzara, Julien Salvadori, Florian Ritzenthaler, Simon Martin, Cl émence Porot and Alessio Imperiale Tags: Original research Source Type: research
3D printed anthropomorphic left ventricular myocardial phantom for nuclear medicine imaging applications
Anthropomorphic torso phantoms, including a cardiac insert, are frequently used to investigate the imaging performance of SPECT and PET systems. These phantom solutions are generally featuring a simple anatomi... (Source: EJNMMI Physics)
Source: EJNMMI Physics - May 3, 2022 Category: Radiology Authors: Janos Kiss, Laszlo Balkay, Kornel Kukuts, Marton Miko, Attila Forgacs, Gyorgy Trencsenyi and Aron K. Krizsan Tags: Original research Source Type: research
Development of a dynamic myocardial perfusion phantom model for tracer kinetic measurements
Absolute myocardial perfusion imaging (MPI) is beneficial in the diagnosis and prognosis of patients with suspected or known coronary artery disease. However, validation and standardization of perfusion estima... (Source: EJNMMI Physics)
Source: EJNMMI Physics - April 25, 2022 Category: Radiology Authors: Marije E. Kamphuis, Henny Kuipers, Jacqueline Verschoor, Johannes C. G. van Hespen, Marcel J. W. Greuter, Riemer H. J. A. Slart and Cornelis H. Slump Tags: Original research Source Type: research
High resolution detectors for whole-body PET scanners by using dual-ended readout
Most current whole-body positron emission tomography (PET) scanners use detectors with high timing resolution to measure the time-of-flight of two 511 keV photons, improving the signal-to-noise ratio of PET im... (Source: EJNMMI Physics)
Source: EJNMMI Physics - April 21, 2022 Category: Radiology Authors: Zheng Liu, Ming Niu, Zhonghua Kuang, Ning Ren, San Wu, Longhan Cong, Xiaohui Wang, Ziru Sang, Crispin Williams and Yongfeng Yang Tags: Original research Source Type: research
166Holmium –99mTechnetium dual-isotope imaging: scatter compensation and automatic healthy-liver segmentation for 166Holmium radioembolization dosimetry
Partition modeling allows personalized activity calculation for holmium-166 (166Ho) radioembolization. However, it requires the definition of tumor and non-tumorous liver, by segmentation and registration of a se... (Source: EJNMMI Physics)
Source: EJNMMI Physics - April 21, 2022 Category: Radiology Authors: Martina Stella, Arthur J. A. T. Braat, Marnix G. E. H. Lam, Hugo W. A. M. de Jong and Rob van Rooij Tags: Original research Source Type: research
Harmonization of [11C]raclopride brain PET images from the HR+ and HRRT: method development and validation in human subjects
There has been an ongoing need to compare and combine the results of new PET imaging studies conducted with [11C]raclopride with older data. This typically means harmonizing data across different scanners. Previo... (Source: EJNMMI Physics)
Source: EJNMMI Physics - April 13, 2022 Category: Radiology Authors: Jocelyn Hoye, Takuya Toyonaga, Yasmin Zakiniaeiz, Gelsina Stanley, Michelle Hampson and Evan D. Morris Tags: Short communication Source Type: research
A mesh-based model of liver vasculature: implications for improved radiation dosimetry to liver parenchyma for radiopharmaceuticals
To develop a model of the internal vasculature of the adult liver and demonstrate its application to the differentiation of radiopharmaceutical decay sites within liver parenchyma from those within organ blood. (Source: EJNMMI Physics)
Source: EJNMMI Physics - April 13, 2022 Category: Radiology Authors: Camilo M. Correa-Alfonso, Julia D. Withrow, Sean J. Domal, Shu Xing, Jungwook Shin, Clemens Grassberger, Harald Paganetti and Wesley E. Bolch Tags: Original research Source Type: research
EARL compliance measurements on the biograph vision Quadra PET/CT system with a long axial field of view
Our aim was to determine sets of reconstruction parameters for the Biograph Vision Quadra (Siemens Healthineers) PET/CT system that result in quantitative images compliant with the European Association of Nucl... (Source: EJNMMI Physics)
Source: EJNMMI Physics - April 8, 2022 Category: Radiology Authors: George A. Prenosil, Michael Hentschel, Thilo Weitzel, Hasan Sari, Kuangyu Shi, Ali Afshar-Oromieh and Axel Rominger Tags: Original research Source Type: research
Hybrid kernelised expectation maximisation for Bremsstrahlung SPECT reconstruction in SIRT with 90Y micro-spheres
Selective internal radiation therapy with Yttrium-90 microspheres is an effective therapy for liver cancer and liver metastases. Yttrium-90 is mainly a high-energy beta particle emitter. These beta particles e... (Source: EJNMMI Physics)
Source: EJNMMI Physics - April 4, 2022 Category: Radiology Authors: Daniel Deidda, Ana M. Denis-Bacelar, Andrew J. Fenwick, Kelley M. Ferreira, Warda Heetun, Brian F. Hutton, Andrew P. Robinson, James Scuffham and Kris Thielemans Tags: Original research Source Type: research
Impact of cyclic changes in pharmacokinetics and absorbed dose in pediatric neuroblastoma patients receiving [177Lu]Lu-DOTATATE
Recent reports personalizing the administered activity (AA) of each cycle of peptide receptor radionuclide therapy based on the predicted absorbed dose (AD) to the kidneys (dose-limiting organ) have been promi... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 28, 2022 Category: Radiology Authors: Javian C. Malcolm, Nadia Falzone, Jennifer E. Gains, Matthew D. Aldridge, David Mirando, Boon Q. Lee, Mark N. Gaze and Katherine A. Vallis Tags: Original research Source Type: research
Small lesion depiction and quantification accuracy of oncological 18F-FDG PET/CT with small voxel and Bayesian penalized likelihood reconstruction
To investigate the influence of small voxel Bayesian penalized likelihood (SVB) reconstruction on small lesion detection compared to ordered subset expectation maximization (OSEM) reconstruction using a clinic... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 26, 2022 Category: Radiology Authors: Lei Xu, Ru-Shuai Li, Run-Ze Wu, Rui Yang, Qin-Qin You, Xiao-Chen Yao, Hui-Fang Xie, Yang Lv, Yun Dong, Feng Wang and Qing-Le Meng Tags: Original research Source Type: research
Impact of a PMMA tube on performances of a Vereos PET/CT system adapted for BSL-3 environment according to the NEMA NU2-2012 standard
A Vereos PET/CT device was adapted to be compatible with the experimentation in large animals within BSL-3 environment. The aim of this study was to investigate the impact of this modification on the performan... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 22, 2022 Category: Radiology Authors: Nidhal Kahlaoui, Thibaut Naninck, Roger Le Grand and Catherine Chapon Tags: Original research Source Type: research
Precision dosimetry in yttrium-90 radioembolization through CT imaging of radiopaque microspheres in a rabbit liver model
To perform precision dosimetry in yttrium-90 radioembolization through CT imaging of radiopaque microspheres in a rabbit liver model and to compare extracted dose metrics to those produced from conventional PE... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 21, 2022 Category: Radiology Authors: E. Courtney Henry, Matthew Strugari, George Mawko, Kimberly Brewer, David Liu, Andrew C. Gordon, Jeffrey N. Bryan, Charles Maitz, Robert Abraham, S. Cheenu Kappadath and Alasdair Syme Tags: Original research Source Type: research
Deep learning for Dixon MRI-based attenuation correction in PET/MRI of head and neck cancer patients
Quantitative whole-body PET/MRI relies on accurate patient-specific MRI-based attenuation correction (AC) of PET, which is a non-trivial challenge, especially for the anatomically complex head and neck region.... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 16, 2022 Category: Radiology Authors: Anders B. Olin, Adam E. Hansen, Jacob H. Rasmussen, Bj örn Jakoby, Anne K. Berthelsen, Claes N. Ladefoged, Andreas Kjær, Barbara M. Fischer and Flemming L. Andersen Tags: Original research Source Type: research
The magnitude of the partial volume effect in SPECT imaging of the kidneys: a phantom study
Single-photon emission computed tomography (SPECT) can cause an over- or underestimation of tissue activity concentration due to limitations in spatial resolution compared to the structures under study. This i... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 14, 2022 Category: Radiology Authors: Andreas Grings, Camille Jobic, Torsten Kuwert and Philipp Ritt Tags: Original research Source Type: research
