Precise activity measurements of medical radionuclides using an ionization chamber: a case study with Terbium-161
161Tb draws an increasing interest in nuclear medicine for therapeutic applications. More than 99% of the emitted gamma and X-rays of 161Tb have an energy below 100 keV. Consequently, precise activity measurement... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 14, 2022 Category: Radiology Authors: Fr édéric Juget, Zeynep Talip, Youcef Nedjadi, M. Teresa Durán, Pascal V. Grundler, Jan Rijn Zeevaart, Nicholas P. van der Meulen and Claude Bailat Tags: Original research Source Type: research

Evaluating different methods of MR-based motion correction in simultaneous PET/MR using a head phantom moved by a robotic system
Due to comparatively long measurement times in simultaneous positron emission tomography and magnetic resonance (PET/MR) imaging, patient movement during the measurement can be challenging. This leads to artif... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 3, 2022 Category: Radiology Authors: Eric Einsp änner, Thies H. Jochimsen, Johanna Harries, Andreas Melzer, Michael Unger, Richard Brown, Kris Thielemans, Osama Sabri and Bernhard Sattler Tags: Original research Source Type: research

Noise sensitivity of 89Zr-Immuno-PET radiomics based on count-reduced clinical images
Low photon count in 89Zr-Immuno-PET results in images with a low signal-to-noise ratio (SNR). Since PET radiomics are sensitive to noise, this study focuses on the impact of noise on radiomic features from 89Zr-I... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 3, 2022 Category: Radiology Authors: Ananthi Somasundaram, David V állez García, Elisabeth Pfaehler, Yvonne W. S. Jauw, Josée M. Zijlstra, Guus A. M. S. van Dongen, Willemien C. Menke-van der Houven van Oordt, Marc C. Huisman, Elisabeth G. E. de Vries and Ronald Boellaard Tags: Original research Source Type: research

Exploration of the total-body PET/CT reconstruction protocol with ultra-low 18F-FDG activity over a wide range of patient body mass indices
The purpose of this study was to investigate the image quality and diagnostic performance of different reconstructions over a wide range of patient body mass indices (BMIs) obtained by total-body PET/CT with u... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 3, 2022 Category: Radiology Authors: Xiuli Sui, Hui Tan, Haojun Yu, Jie Xiao, Chi Qi, Yanyan Cao, Shuguang Chen, Yiqiu Zhang, Pengcheng Hu and Hongcheng Shi Tags: Original research Source Type: research

Correction to: Use of non-Gaussian time-of-flight kernels for image reconstruction of Monte Carlo simulated data of ultra-fast PET scanners
(Source: EJNMMI Physics)
Source: EJNMMI Physics - February 24, 2022 Category: Radiology Authors: Nikos Efthimiou, Kris Thielemans, Elise Emond, Chris Cawthorne, Stephen J. Archibald and Charalampos Tsoumpas Tags: Correction Source Type: research

Assessment of mouse-specific pharmacokinetics in kidneys based on 131I activity measurements using micro-SPECT
In order to acquire accurate drug pharmacokinetic information, which is required for tissue dosimetry, micro-SPECT must be quantitative to allow for an accurate assessment of radioligand activity in the releva... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 23, 2022 Category: Radiology Authors: Clarita Saldarriaga Vargas, Lara Struelens, Matthias D ’Huyvetter, Vicky Caveliers and Peter Covens Tags: Original research Source Type: research

A multicentre simulation study of planar whole-body bone scintigraphy in Sweden
Whole-body bone scintigraphy is a clinically useful non-invasive and highly sensitive imaging method enabling detection of metabolic changes at an early stage of disease, often earlier than with conventional r... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 14, 2022 Category: Radiology Authors: Agnetha Gustafsson, Eva Örndahl, David Minarik, Kerstin Cederholm, Sophia Frantz, Jessica Hagerman, Lena Johansson, Johan Fredén Lindqvist and Cathrine Jonsson Tags: Original research Source Type: research

Free-breathing 3D Stack of Stars GRE (StarVIBE) sequence for detecting pulmonary nodules in 18F-FDG PET/MRI
The free-breathing T1-weighted 3D Stack of Stars GRE (StarVIBE) MR sequence potentially reduces artifacts in chest MRI. The purpose of this study was to evaluate StarVIBE for the detection of pulmonary nodules... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 7, 2022 Category: Radiology Authors: Nils Martin Bruckmann, Julian Kirchner, Janna Morawitz, Lale Umutlu, Wolfgang P. Fendler, Ken Herrmann, Ann-Kathrin Bittner, Oliver Hoffmann, Tanja Fehm, Maike E. Lindemann, Christian Buchbender, Gerald Antoch and Lino M. Sawicki Tags: Original research Source Type: research

What validation tests can be done by the clinical medical physicist while waiting for the standardization of quantitative SPECT/CT imaging?
The aim of the study was to assess the accuracy of quantitative SPECT/CT imaging in a clinical setting and to compare test results from two nuclear medicine departments. (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 5, 2022 Category: Radiology Authors: Hanna Piwowarska-Bilska, Aleksandra Supi ńska and Bożena Birkenfeld Tags: Original research Source Type: research

A novel semiautomated method for background activity and biological tumour volume definition to improve standardisation of 18F-FET PET imaging in glioblastoma
Multicentre clinical trials evaluating the role of 18F-Fluoroethyl-l-tyrosine (18F-FET) PET as a diagnostic biomarker in glioma management have highlighted a need for standardised methods of data analysis. 18F-FE... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 5, 2022 Category: Radiology Authors: Caterina Brighi, Simon Puttick, Shenpeng Li, Paul Keall, Katherine Neville, David Waddington, Pierrick Bourgeat, Ashley Gillman and Michael Fay Tags: Original research Source Type: research

Performance evaluation of the IRIS XL-220 PET/CT system, a new camera dedicated to non-human primates
Non-human primates (NHP) are critical in biomedical research to better understand the pathophysiology of diseases and develop new therapies. Based on its translational and longitudinal abilities along with its... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 5, 2022 Category: Radiology Authors: Fr édéric Boisson, Sophie Serriere, Liji Cao, Sylvie Bodard, Alessandro Pilleri, Lionel Thomas, Giancarlo Sportelli, Johnny Vercouillie, Patrick Emond, Clovis Tauber, Nicola Belcari, Jean-Luc Lefaucheur, David Brasse and Laurent Galineau Tags: Original research Source Type: research

Deep learning-assisted PET imaging achieves fast scan/low-dose examination
This study aimed to investigate the impact of a deep learning (DL)-based denoising method on the image quality and lesion detectability of 18F-FDG positron emission tomography (PET) images. (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 4, 2022 Category: Radiology Authors: Yan Xing, Wenli Qiao, Taisong Wang, Ying Wang, Chenwei Li, Yang Lv, Chen Xi, Shu Liao, Zheng Qian and Jinhua Zhao Tags: Original research Source Type: research

Freely available convolutional neural network-based quantification of PET/CT lesions is associated with survival in patients with lung cancer
Metabolic positron emission tomography/computed tomography (PET/CT) parameters describing tumour activity contain valuable prognostic information, but to perform the measurements manually leads to both intra- ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 3, 2022 Category: Radiology Authors: Pablo Borrelli, Jos é Luis Loaiza Góngora, Reza Kaboteh, Johannes Ulén, Olof Enqvist, Elin Trägårdh and Lars Edenbrandt Tags: Original research Source Type: research

Evaluating two respiratory correction methods for abdominal PET/MRI imaging
To evaluate two respiratory correction methods for abdominal PET/MRI images and further to analyse the effects on standard uptake values (SUVs) of respiratory motion correction, 17 patients with 25 abdominal l... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 31, 2022 Category: Radiology Authors: Weiwei Ruan, Fang Liu, Xun Sun, Fan Hu, Tingfan Wu, Yongxue Zhang and Xiaoli Lan Tags: Original research Source Type: research

Aortic valve imaging using 18F-sodium fluoride: impact of triple motion correction
Current 18F-NaF assessments of aortic valve microcalcification using 18F-NaF PET/CT are based on evaluations of end-diastolic or cardiac motion-corrected (ECG-MC) images, which are affected by both patient and re... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 29, 2022 Category: Radiology Authors: Martin Lyngby Lassen, Evangelos Tzolos, Daniele Massera, Sebastien Cadet, Rong Bing, Jacek Kwiecinski, Damini Dey, Daniel S. Berman, Marc R. Dweck, David E. Newby and Piotr J. Slomka Tags: Original research Source Type: research