Impact of segmentation and discretization on radiomic features in 68Ga-DOTA-TOC PET/CT images of neuroendocrine tumor
To identify the impact of segmentation methods and intensity discretization on radiomic features (RFs) extraction from 68Ga-DOTA-TOC PET images in patients with neuroendocrine tumors. (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 27, 2021 Category: Radiology Authors: Virginia Liberini, Bruno De Santi, Osvaldo Rampado, Elena Gallio, Beatrice Dionisi, Francesco Ceci, Giulia Polverari, Philippe Thuillier, Filippo Molinari and D ésirée Deandreis Tags: Original research Source Type: research

Cross-validation study between the HRRT and the PET component of the SIGNA PET/MRI system with focus on neuroimaging
The Siemens high-resolution research tomograph (HRRT - a dedicated brain PET scanner) is to this day one of the highest resolution PET scanners; thus, it can serve as useful benchmark when evaluating performan... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 26, 2021 Category: Radiology Authors: Julia G. Mannheim, Ju-Chieh (Kevin) Cheng, Nasim Vafai, Elham Shahinfard, Carolyn English, Jessamyn McKenzie, Jing Zhang, Laura Barlow and Vesna Sossi Tags: Original research Source Type: research

Head-to-head comparison of a Si-photomultiplier-based and a conventional photomultiplier-based PET-CT system
A novel generation of PET scanners based on silicon (Si)-photomultiplier (PM) technology has recently been introduced. Concurrently, there has been development of new reconstruction methods aimed at increasing... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 25, 2021 Category: Radiology Authors: Jenny Oddstig, Gustav Brolin, Elin Tr ägårdh and David Minarik Tags: Original research Source Type: research

Standard MRI-based attenuation correction for PET/MRI phantoms: a novel concept using MRI-visible polymer
We present a PET/MRI phantom built from MRI-visible m... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 18, 2021 Category: Radiology Authors: Ivo Rausch, Alejandra Valladares, Lalith Kumar Shiyam Sundar, Thomas Beyer, Marcus Hacker, Martin Meyerspeer and Ewald Unger Tags: Original research Source Type: research

Quantitative imaging of bone remodeling in patients with a unicompartmental joint unloading knee implant (ATLAS Knee System) —effect of metal artifacts on a SPECT-CT-based quantification
SPECT-CT using radiolabeled phosphonates is considered a standard for assessing bone metabolism (e.g., in patients with osteoarthritis of knee joints). However, SPECT can be influenced by metal artifacts in CT... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 17, 2021 Category: Radiology Authors: Oliver S. Grosser, Marcus Klutzny, Heiko Wissel, Dennis Kupitz, Michael Finger, Simone Schenke, Jan Wuestemann, Christoph H. Lohmann, Christoph Hoeschen, Maciej Pech, Christian Staerke and Michael C. Kreissl Tags: Original research Source Type: research

Theranostic SPECT reconstruction for improved resolution: application to radionuclide therapy dosimetry
SPECT-derived dose estimates in tissues of diameter less than 3 × system resolution are subject to significant losses due to the limited spatial resolution of the gamma camera. Incorporating resolution modellin... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 17, 2021 Category: Radiology Authors: H. Marquis, D. Deidda, A. Gillman, K. P. Willowson, Y. Gholami, T. Hioki, E. Eslick, K. Thielemans and D. L. Bailey Tags: Original research Source Type: research

Evaluation of SUVlean consistency in FDG and PSMA PET/MR with Dixon-, James-, and Janma-based lean body mass correction
To systematically evaluate the consistency of various standardized uptake value (SUV) lean body mass (LBM) normalization methods in a clinical positron emission tomography/magnetic resonance imaging (PET/MR) s... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 17, 2021 Category: Radiology Authors: Jun Zhao, Qiaoyi Xue, Xing Chen, Zhiwen You, Zhe Wang, Jianmin Yuan, Hui Liu and Lingzhi Hu Tags: Original research Source Type: research

Comparing lesion detection efficacy and image quality across different PET system generations to optimize the iodine-124 PET protocol for recurrent thyroid cancer
In recurrent differentiated thyroid cancer patients, detectability in 124I PET is limited for lesions with low radioiodine uptake. We assess the improvements in lesion detectability and image quality between thre... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 15, 2021 Category: Radiology Authors: David Kersting, Walter Jentzen, Miriam Sraieb, Pedro Fragoso Costa, Maurizio Conti, Lale Umutlu, Gerald Antoch, Michael Nader, Ken Herrmann, Wolfgang Peter Fendler, Christoph Rischpler and Manuel Weber Tags: Original research Source Type: research

Can a penalized-likelihood estimation algorithm be used to reduce the injected dose or the acquisition time in 68Ga-DOTATATE PET/CT studies?
Image quality and quantitative accuracy of positron emission tomography (PET) depend on several factors such as uptake time, scanner characteristics and image reconstruction methods. Ordered subset expectation... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 12, 2021 Category: Radiology Authors: Alexandre Chicheportiche, Elinor Goshen, Jeremy Godefroy, Simona Grozinsky-Glasberg, Kira Oleinikov, Amichay Meirovitz, David J. Gross and Simona Ben-Haim Tags: Original research Source Type: research

A method for evaluation of patient-specific lean body mass from limited-coverage CT images and its application in PERCIST: comparison with predictive equation
Standardized uptake value (SUV) normalized by lean body mass ([LBM] SUL) is recommended as metric by PERCIST 1.0. The James predictive equation (PE) is a frequently used formula for LBM estimation, but may cau... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 8, 2021 Category: Radiology Authors: Jingjie Shang, Zhiqiang Tan, Yong Cheng, Yongjin Tang, Bin Guo, Jian Gong, Xueying Ling, Lu Wang and Hao Xu Tags: Original research Source Type: research

Use of population input functions for reduced scan duration whole-body Patlak 18F-FDG PET imaging
Whole-body Patlak images can be obtained from an acquisition of first 6  min of dynamic imaging over the heart to obtain the arterial input function (IF), followed by multiple whole-body sweeps up to 60 min pi.... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 5, 2021 Category: Radiology Authors: Joyce van Sluis, Maqsood Yaqub, Adrienne H. Brouwers, Rudi A. J. O. Dierckx, Walter Noordzij and Ronald Boellaard Tags: Short communication Source Type: research

Clinical validation of time reduction strategy in continuous step-and-shoot mode during SPECT acquisition
The SwiftScan solution (General Electric Healthcare) combines a new low-energy high-resolution sensitivity collimator and a tomographic step-and-shoot continuous (SSC) mode acquisition. The purpose of this study ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 2, 2021 Category: Radiology Authors: Valentin Picone, Nikolaos Makris, Fanny Boutevin, Sarah Roy, Margot Playe and Michael Soussan Tags: Original research Source Type: research

Correction to: Combined quality and dose-volume histograms for assessing the predictive value of 99mTc-MAA SPECT/CT simulation for personalizing radioembolization treatment in liver metastatic colorectal cancer
An amendment to this paper has been published and can be accessed via the original article. (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 27, 2021 Category: Radiology Authors: Hugo Levillain, Manuela Burghelea, Ivan Duran Derijckere, Thomas Guiot, Akos Gulyban, Bruno Vanderlinden, Michael Vouche, Patrick Flamen and Nick Reynaert Tags: Correction Source Type: research

A methodological investigation of healthy tissue, hepatocellular carcinoma, and other lesions with dynamic 68Ga-FAPI-04 PET/CT imaging
The study aimed to establish a 68Ga-FAPI-04 kinetic model in hepatic lesions, to determine the potential role of kinetic parameters in the differentiation of hepatocellular carcinoma (HCC) from non-HCC lesions. (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 22, 2021 Category: Radiology Authors: Barbara Katharina Geist, Haiqun Xing, Jingnan Wang, Ximin Shi, Haitao Zhao, Marcus Hacker, Xinting Sang, Li Huo and Xiang Li Tags: Short communication Source Type: research

Effect of data conserving respiratory motion compensation on left ventricular functional parameters assessed in gated myocardial perfusion SPECT
Respiratory motion compromises image quality in myocardial perfusion (MP) single-photon emission computed tomography (SPECT) imaging and may affect analysis of left ventricular (LV) functional parameters, incl... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 21, 2021 Category: Radiology Authors: Matti J Kortelainen, Tuomas M Koivum äki, Marko J Vauhkonen and Mikko A Hakulinen Tags: Original research Source Type: research

Improved image reconstruction of 89Zr-immunoPET studies using a Bayesian penalized likelihood reconstruction algorithm
The aim of this study was to evaluate the use of a Bayesian penalized likelihood reconstruction algorithm (Q.Clear) for 89Zr-immunoPET image reconstruction and its potential to improve image quality and reduce th... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 19, 2021 Category: Radiology Authors: Julian Kirchner, Joseph A. O ’Donoghue, Anton S. Becker and Gary A. Ulaner Tags: Original research Source Type: research

Evaluation of image quality at the detector ’s edge of dedicated breast positron emission tomography
Using phantoms and clinical studies in prone hanging breast imaging, we assessed the image quality of a commercially available dedicated breast PET (dbPET) at the detector ’s edge, where mammary glands near the... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 18, 2021 Category: Radiology Authors: Yoko Satoh, Utaroh Motosugi, Masamichi Imai, Yoshie Omiya and Hiroshi Onishi Tags: Original research Source Type: research

Individual dosimetry system for targeted alpha therapy based on PHITS coupled with microdosimetric kinetic model
An individual dosimetry system is essential for the evaluation of precise doses in nuclear medicine. The purpose of this study was to develop a system for calculating not only absorbed doses but also EQDX( α/β) fr... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 12, 2021 Category: Radiology Authors: Tatsuhiko Sato, Takuya Furuta, Yuwei Liu, Sadahiro Naka, Shushi Nagamori, Yoshikatsu Kanai and Tadashi Watabe Tags: Original research Source Type: research

Assessment of cardiac amyloidosis with 99mTc-pyrophosphate (PYP) quantitative SPECT
This study was aimed to assess the diagn... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 7, 2021 Category: Radiology Authors: Chao Ren, Jingyun Ren, Zhuang Tian, Yanrong Du, Zhixin Hao, Zongyao Zhang, Wei Fang, Fang Li, Shuyang Zhang, Bailing Hsu and Li Huo Tags: Original research Source Type: research

Quantitative bone SPECT/CT reconstruction utilizing anatomical information
Bone SPECT/CT has been shown to offer superior sensitivity and specificity compared to conventional whole-body planar scanning. Furthermore, bone SPECT/CT allows quantitative imaging, which is challenging with... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 6, 2021 Category: Radiology Authors: Tuija S. Kangasmaa, Chris Constable and Antti O. Sohlberg Tags: Original research Source Type: research

Fully digital PET is unaffected by any deterioration in TOF resolution and TOF image quality in the wide range of routine PET count rates
Digital PET involving silicon photomultipliers (SiPM) provides an enhanced time-of-flight (TOF) resolution as compared with photomultiplier (PMT)-based PET, but also a better prevention of the count-related ri... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 6, 2021 Category: Radiology Authors: Julien Salvadori, Freddy Odille, Gilles Karcher, Pierre-Yves Marie and Laetitia Imbert Tags: Original research Source Type: research

Accuracy and precision of zero-echo-time, single- and multi-atlas attenuation correction for dynamic [11C]PE2I PET-MR brain imaging
A valid photon attenuation correction (AC) method is instrumental for obtaining quantitatively correct PET images. Integrated PET/MR systems provide no direct information on attenuation, and novel methods for ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - December 28, 2020 Category: Radiology Authors: Jo ão M. Sousa, Lieuwe Appel, Inés Merida, Rolf A. Heckemann, Nicolas Costes, Mathias Engström, Stergios Papadimitriou, Dag Nyholm, Håkan Ahlström, Alexander Hammers and Mark Lubberink Tags: Original research Source Type: research

Combined quality and dose-volume histograms for assessing the predictive value of 99mTc-MAA SPECT/CT simulation for personalizing radioembolization treatment in liver metastatic colorectal cancer
The relationship between the mean absorbed dose delivered to the tumour and the outcome in liver metastases from colorectal cancer patients treated with radioembolization has already been presented in several ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - December 14, 2020 Category: Radiology Authors: Hugo Levillain, Manuela Burghelea, Ivan Duran Derijckere, Thomas Guiot, Akos Gulyban, Bruno Vanderlinden, Michael Vouche, Patrick Flamen and Nick Reynaert Tags: Original research Source Type: research

Automated quantification of baseline imaging PET metrics on FDG PET/CT images of pediatric Hodgkin lymphoma patients
For pediatric lymphoma, quantitative FDG PET/CT imaging features such as metabolic tumor volume (MTV) are important for prognosis and risk stratification strategies. However, feature extraction is difficult an... (Source: EJNMMI Physics)
Source: EJNMMI Physics - December 14, 2020 Category: Radiology Authors: Amy J. Weisman, Jihyun Kim, Inki Lee, Kathleen M. McCarten, Sandy Kessel, Cindy L. Schwartz, Kara M. Kelly, Robert Jeraj, Steve Y. Cho and Tyler J. Bradshaw Tags: Original research Source Type: research

Kidney dosimetry in 777 patients during 177Lu-DOTATATE therapy: aspects on extrapolations and measurement time points
Fractionated peptide receptor radionuclide therapy (PRRT) with 177Lu-DOTATATE is increasingly applied as an effective treatment for patients with disseminated neuroendocrine tumors. In parallel to dose planning b... (Source: EJNMMI Physics)
Source: EJNMMI Physics - December 9, 2020 Category: Radiology Authors: Mattias Sandstr öm, Nanette Freedman, Katarzyna Fröss-Baron, Tanweera Kahn and Anders Sundin Tags: Original research Source Type: research

Tumor response prediction in 90Y radioembolization with PET-based radiomics features and absorbed dose metrics
To evaluate whether lesion radiomics features and absorbed dose metrics extracted from post-therapy 90Y PET can be integrated to better predict outcomes in microsphere radioembolization of liver malignancies (Source: EJNMMI Physics)
Source: EJNMMI Physics - December 9, 2020 Category: Radiology Authors: Lise Wei, Can Cui, Jiarui Xu, Ravi Kaza, Issam El Naqa and Yuni K. Dewaraja Tags: Original research Source Type: research

Impact of the dosimetry approach on the resulting 90Y radioembolization planned absorbed doses based on 99mTc-MAA SPECT-CT: is there agreement between dosimetry methods?
Prior radioembolization, a simulation using 99mTc-macroaggregated albumin as 90Y-microspheres surrogate is performed. Gamma scintigraphy images (planar, SPECT, or SPECT-CT) are acquired to evaluate intrahepatic 9... (Source: EJNMMI Physics)
Source: EJNMMI Physics - December 7, 2020 Category: Radiology Authors: Ver ónica Morán, Elena Prieto, Lidia Sancho, Macarena Rodríguez-Fraile, Leticia Soria, Arantxa Zubiria and Josep M. Martí-Climent Tags: Original research Source Type: research

A simulation study on using 252Cf for the treatment of esophagus tumor in human phantom
Due to the sensitivity of this tissue, and the potential for metastasis of its cancer as well, finding accurate methods to be employed for the treatment of esophagus tumors is of especial interest for the rese... (Source: EJNMMI Physics)
Source: EJNMMI Physics - December 3, 2020 Category: Radiology Authors: Fatemeh S. Rasouli, Hasan Bakhshandeh and S. Mohsen Salehkoutahi Tags: Original research Source Type: research

Assessment of population-based input functions for Patlak imaging of whole body dynamic 18F-FDG PET
Arterial blood sampling is the gold standard method to obtain the arterial input function (AIF) for quantification of whole body (WB) dynamic 18F-FDG PET imaging. However, this procedure is invasive and not typic... (Source: EJNMMI Physics)
Source: EJNMMI Physics - November 23, 2020 Category: Radiology Authors: Mika Naganawa, Jean-Dominique Gallezot, Vijay Shah, Tim Mulnix, Colin Young, Mark Dias, Ming-Kai Chen, Anne M. Smith and Richard E. Carson Tags: Original research Source Type: research

Improved PET/MRI attenuation correction in the pelvic region using a statistical decomposition method on T2-weighted images
Attenuation correction of PET/MRI is a remaining problem for whole-body PET/MRI. The statistical decomposition algorithm (SDA) is a probabilistic atlas-based method that calculates synthetic CTs from T2-weight... (Source: EJNMMI Physics)
Source: EJNMMI Physics - November 23, 2020 Category: Radiology Authors: Elin Wallst én, Jan Axelsson, Joakim Jonsson, Camilla Thellenberg Karlsson, Tufve Nyholm and Anne Larsson Tags: Original research Source Type: research

An international multi-center investigation on the accuracy of radionuclide calibrators in nuclear medicine theragnostics
Personalized molecular radiotherapy based on theragnostics requires accurate quantification of the amount of radiopharmaceutical activity administered to patients both in diagnostic and therapeutic application... (Source: EJNMMI Physics)
Source: EJNMMI Physics - November 23, 2020 Category: Radiology Authors: Clarita Saldarriaga Vargas, Matthias Bauwens, Ivo N. A. Pooters, Stefaan Pomm é, Steffie M. B. Peters, Marcel Segbers, Walter Jentzen, Andreas Vogg, Floris H. P. van Velden, Sebastiaan L. Meyer Viol, Martin Gotthardt, Felix M. Mottaghy, Joachim E. Wildbe Tags: Original research Source Type: research

Direct comparison of brain [18F]FDG images acquired by SiPM-based and PMT-based PET/CT: phantom and clinical studies
Silicon photomultiplier-positron emission tomography (SiPM-PET) has better sensitivity, spatial resolution, and timing resolution than photomultiplier tube (PMT)-PET. The present study aimed to clarify the adv... (Source: EJNMMI Physics)
Source: EJNMMI Physics - November 23, 2020 Category: Radiology Authors: Kei Wagatsuma, Muneyuki Sakata, Kenji Ishibashi, Akira Hirayama, Hirofumi Kawakami, Kenta Miwa, Yukihisa Suzuki and Kenji Ishii Tags: Original research Source Type: research

Halo artifacts of indwelling urinary catheter by inaccurate scatter correction in 18F-FDG PET/CT imaging: incidence, mechanism, and solutions
Halo artifacts from urinary catheters can occur due to inaccurate scatter correction, and the artifacts affect the tumor visibility in 18F-FDG PET/CT images. We investigated the incidence rate and the mechanisms ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - November 13, 2020 Category: Radiology Authors: Keiichi Magota, Naoto Numata, Daiki Shinyama, Junya Katahata, Yamato Munakata, Piotr J. Maniawski, Kentaro Kobayashi, Osamu Manabe, Kenji Hirata, Ukihide Tateishi, Kohsuke Kudo and Tohru Shiga Tags: Original research Source Type: research

High-quality brain perfusion SPECT images may be achieved with a high-speed recording using 360 ° CZT camera
The aim of this study was to compare brain perfusion SPECT obtained from a 360 ° CZT and a conventional Anger camera. (Source: EJNMMI Physics)
Source: EJNMMI Physics - November 4, 2020 Category: Radiology Authors: Manon Bordonne, Mohammad B. Chawki, Pierre-Yves Marie, Timoth ée Zaragori, Véronique Roch, Rachel Grignon, Laetitia Imbert and Antoine Verger Tags: Original research Source Type: research

Performance evaluation of fifth-generation ultra-high-resolution SPECT system with two stationary detectors and multi-pinhole imaging
Small-animal single-photon emission computed tomography (SPECT) systems with multi-pinhole collimation and large stationary detectors have advantages compared to systems with moving small detectors. These syst... (Source: EJNMMI Physics)
Source: EJNMMI Physics - November 2, 2020 Category: Radiology Authors: Jan V. Hoffmann, Jan P. Janssen, Takayuki Kanno, Takayuki Shibutani, Masahisa Onoguchi, Constantin Lapa, Jan-Peter Grunz, Andreas K. Buck and Takahiro Higuchi Tags: Original research Source Type: research

Uncertainty analysis of tumour absorbed dose calculations in molecular radiotherapy
Internal dosimetry evaluation consists of a multi-step process ranging from imaging acquisition to absorbed dose calculations. Assessment of uncertainty is complicated and, for that reason, it is commonly igno... (Source: EJNMMI Physics)
Source: EJNMMI Physics - October 12, 2020 Category: Radiology Authors: Domenico Finocchiaro, Jonathan I. Gear, Federica Fioroni, Glenn D. Flux, Iain Murray, Gastone Castellani, Annibale Versari, Mauro Iori and Elisa Grassi Tags: Original research Source Type: research

Influence of X-ray computed tomography (CT) exposure and reconstruction parameters on positron emission tomography (PET) quantitation
The CT of PET CT provides diagnostic information, anatomic localisation and attenuation correction (AC). When only AC is required, very lose dose CT is desirable. CT iterative reconstruction (IR) improves imag... (Source: EJNMMI Physics)
Source: EJNMMI Physics - October 9, 2020 Category: Radiology Authors: Ivan Ho Shon, Christopher Reece, Thomas Hennessy, Megan Horsfield and Bruce McBride Tags: Original research Source Type: research

Setting up a quantitative SPECT imaging network for a European multi-centre dosimetry study of radioiodine treatment for thyroid cancer as part of the MEDIRAD project
Differentiated thyroid cancer has been treated with radioiodine for almost 80  years, although controversial questions regarding radiation-related risks and the optimisation of treatment regimens remain unresol... (Source: EJNMMI Physics)
Source: EJNMMI Physics - October 8, 2020 Category: Radiology Authors: Jan Taprogge, Francesca Leek, Tino Schurrat, Johannes Tran-Gia, Delphine Vallot, Manuel Bardi ès, Uta Eberlein, Michael Lassmann, Susanne Schlögl, Alex Vergara Gil and Glenn D. Flux Tags: Original research Source Type: research

Advances on inorganic scintillator-based optic fiber dosimeters
This article presents a new perspective on the development of inorganic scintillator-based fiber dosimeters (IOSFDs) for medical radiotherapy dosimetry (RTD) focusing on real-time in vivo dosimetry. The scinti... (Source: EJNMMI Physics)
Source: EJNMMI Physics - October 6, 2020 Category: Radiology Authors: Liang Ding, Qiong Wu, Qun Wang, Yamei Li, Richard M. Perks and Liang Zhao Tags: Review Source Type: research

Development and evaluation of an automated quantification tool for amyloid PET images
Quantitative evaluation of amyloid positron emission tomography (PET) with standardized uptake value ratio (SUVR) plays a key role in clinical studies of Alzheimer ’s disease (AD). We have proposed a PET-only (... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 29, 2020 Category: Radiology Authors: Yuma Tsubaki, Go Akamatsu, Natsumi Shimokawa, Suguru Katsube, Aya Takashima and Masayuki Sasaki Tags: Young investigators Source Type: research

Human dosimetry of free 211At and meta-[211At]astatobenzylguanidine (211At-MABG) estimated using preclinical biodistribution from normal mice
211At is one of the ideal nuclides for targeted radionuclide therapies (TRTs). Meta-[211At]astatobenzylguanidine (211At-MABG) has been proposed for the treatment of pheochromocytoma. To effectively use these radi... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 22, 2020 Category: Radiology Authors: Naoyuki Ukon, Songji Zhao, Kohshin Washiyama, Noboru Oriuchi, Chengbo Tan, Saki Shimoyama, Miho Aoki, Hitoshi Kubo, Kazuhiro Takahashi and Hiroshi Ito Tags: Original research Source Type: research

Error propagation analysis of seven partial volume correction algorithms for [18F]THK-5351 brain PET imaging
Novel partial volume correction (PVC) algorithms have been validated by assuming ideal conditions of image processing; however, in real clinical PET studies, the input datasets include error sources which caus... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 14, 2020 Category: Radiology Authors: Senri Oyama, Ayumu Hosoi, Masanobu Ibaraki, Colm J. McGinnity, Keisuke Matsubara, Shoichi Watanuki, Hiroshi Watabe, Manabu Tashiro and Miho Shidahara Tags: Original research Source Type: research

Optimization of a Bayesian penalized likelihood algorithm (Q.Clear) for 18F-NaF bone PET/CT images acquired over shorter durations using a custom-designed phantom
The Bayesian penalized likelihood (BPL) algorithm Q.Clear (GE Healthcare) allows fully convergent iterative reconstruction that results in better image quality and quantitative accuracy, while limiting image n... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 11, 2020 Category: Radiology Authors: Tokiya Yoshii, Kenta Miwa, Masashi Yamaguchi, Kai Shimada, Kei Wagatsuma, Tensho Yamao, Yuto Kamitaka, Seiya Hiratsuka, Rinya Kobayashi, Hajime Ichikawa, Noriaki Miyaji, Tsuyoshi Miyazaki and Kenji Ishii Tags: Original research Source Type: research

From a PMT-based to a SiPM-based PET system: a study to define matched acquisition/reconstruction parameters and NEMA performance of the Biograph Vision 450
The purpose of this work was to propose an approach based on noise measurement to adapt present clinical acquisition and reconstruction parameters adapted to a PMT-based system (Biograph mCT) to a SiPM-based s... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 3, 2020 Category: Radiology Authors: Thomas Carlier, Ludovic Ferrer, Maurizio Conti, Caroline Bodet-Milin, Caroline Rousseau, Yanic Bercier, Bernard Bendriem and Fran çoise Kraeber-Bodéré Tags: Original research Source Type: research

68Ga-PSMA-11 PET/MRI: determining ideal acquisition times to reduce noise and increase image quality
In this study, we investigate the impact of increased PET acquisition time per bed position on lesion detectability, standard uptake value, and image noise in 68Ga-PSMA-11 PET/MRI scans. (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 26, 2020 Category: Radiology Authors: Vishnu Murthy, Raven L. Smith, Dora H. Tao, Courtney A. Lawhn-Heath, Dave E. Korenchan, Peder E. Z. Larson, Robert R. Flavell and Thomas A. Hope Tags: Original research Source Type: research

Distribution modeling of nanoparticles for brachytherapy of human eye tumor
Due to their unique properties, gold nanoparticles (GNPs) have been proposed to be used for a wide range of applications, especially for photon radiation therapy. In addition to experimental works, there are w... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 20, 2020 Category: Radiology Authors: S. Farhad Masoudi, Fahimeh S. Daryabari and Fatemeh S. Rasouli Tags: Original research Source Type: research

A realistic phantom of the human head for PET-MRI
The combination of positron emission tomography (PET) and magnetic resonance imaging (MRI) (PET-MRI) is a unique hybrid imaging modality mainly used in oncology and neurology. The MRI-based attenuation correct... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 5, 2020 Category: Radiology Authors: Johanna Harries, Thies H. Jochimsen, Thomas Scholz, Tina Schlender, Henryk Barthel, Osama Sabri and Bernhard Sattler Tags: Original research Source Type: research

RECOMIA —a cloud-based platform for artificial intelligence research in nuclear medicine and radiology
Artificial intelligence (AI) is about to transform medical imaging. The Research Consortium for Medical Image Analysis (RECOMIA), a not-for-profit organisation, has developed an online platform to facilitate c... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 4, 2020 Category: Radiology Authors: Elin Tr ägårdh, Pablo Borrelli, Reza Kaboteh, Tony Gillberg, Johannes Ulén, Olof Enqvist and Lars Edenbrandt Tags: Original research Source Type: research

An in vivo multimodal feasibility study in a rat brain tumour model using flexible multinuclear MR and PET systems
In addition to the structural information afforded by 1H MRI, the use of X-nuclei, such as sodium-23 (23Na) or phosphorus-31 (31P), offers important complementary information concerning physiological and biochemi... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 29, 2020 Category: Radiology Authors: Chang-Hoon Choi, Carina Stegmayr, Aliaksandra Shymanskaya, Wieland A. Worthoff, Nuno A. da Silva, J örg Felder, Karl-Josef Langen and N. Jon Shah Tags: Original research Source Type: research

Monte Carlo-based scatter correction for the SMARTZOOM collimator
Myocardial perfusion imaging is a commonly performed SPECT protocol and hence it would be beneficial if its scan duration could be shortened. For traditional gamma cameras, two developments have separately sho... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 22, 2020 Category: Radiology Authors: Martijn M. A. Dietze, Britt Kunnen, Martina Stella and Hugo W. A. M. de Jong Tags: Original research Source Type: research