Feasibility of positron range correction in 82-Rubidium cardiac PET/CT
Myocardial perfusion imaging (MPI) using positron emission tomography (PET) tracers is an essential tool in investigating diseases and treatment responses in cardiology. 82Rubidium (82Rb)-PET imaging is advantage... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 30, 2022 Category: Radiology Authors: Malte Jensen, Simon Bentsen, Andreas Clemmensen, Jacob Kildevang Jensen, Johanne Madsen, Jonas Rossing, Anna Laier, Philip Hasbak, Andreas Kjaer and Rasmus Sejersten Ripa Tags: Original research Source Type: research
Small-scale dosimetry for alpha particle 241Am source cell irradiation and estimation of γ-H2AX foci distribution in prostate cancer cell line PC3
The development of new targeted alpha therapies motivates improving alpha particle dosimetry. For alpha particles, microscopic targets must be considered to estimate dosimetric quantities that can predict the ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 19, 2022 Category: Radiology Authors: Emma Mellhammar, Magnus Dahlbom, Oskar Vilhelmsson-Timmermand and Sven-Erik Strand Tags: Original research Source Type: research
Analysis of a deep learning-based method for generation of SPECT projections based on a large Monte Carlo simulated dataset
In recent years, a lot of effort has been put in the enhancement of medical imaging using artificial intelligence. However, limited patient data in combination with the unavailability of a ground truth often p... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 19, 2022 Category: Radiology Authors: Julian Leube, Johan Gustafsson, Michael Lassmann, Maikol Salas-Ramirez and Johannes Tran-Gia Tags: Original research Source Type: research
Optimizing acquisition times for total-body positron emission tomography/computed tomography with half-dose 18F-fluorodeoxyglucose in oncology patients
The present study aimed to explore the boundary of acquisition time and propose an optimized acquisition time range for total-body positron emission tomography (PET)/computed tomography (CT) oncological imagin... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 8, 2022 Category: Radiology Authors: Yibo He, Yushen Gu, Haojun Yu, Bing Wu, Siyang Wang, Hui Tan, Yanyan Cao, Shuguang Chen, Xiuli Sui, Yiqiu Zhang and Hongcheng Shi Tags: Original research Source Type: research
Simplified dosimetry for kidneys and tumors in 177Lu-labeled peptide receptor radionuclide therapy
To evaluate if satisfactory post-therapeutic image-based dosimetry can be achieved for Lu-177-DOTATATE treatments using a reduced number of image acquisitions to improve patient comfort and reduce economical c... (Source: EJNMMI Physics)
Source: EJNMMI Physics - June 20, 2022 Category: Radiology Authors: Oscar Ardenfors, Joachim N. Nilsson, Daniel Thor and Cecilia Hindorf Tags: Original research Source Type: research
NEMA characterization of the SAFIR prototype PET insert
The SAFIR prototype insert is a preclinical Positron Emission Tomography (PET) scanner built to acquire dynamic images simultaneously with a 7 T Bruker Magnetic Resonance Imaging (MRI) scanner. The insert is d... (Source: EJNMMI Physics)
Source: EJNMMI Physics - June 13, 2022 Category: Radiology Authors: Parisa Khateri, Werner Lustermann, Christian Ritzer, Charalampos Tsoumpas and G ünther Dissertori Tags: Original research Source Type: research
Ultra high speed SPECT bone imaging enabled by a deep learning enhancement method: a proof of concept
To generate high-quality bone scan SPECT images from only 1/7 scan time SPECT images using deep learning-based enhancement method. (Source: EJNMMI Physics)
Source: EJNMMI Physics - June 13, 2022 Category: Radiology Authors: Boyang Pan, Na Qi, Qingyuan Meng, Jiachen Wang, Siyue Peng, Chengxiao Qi, Nan-Jie Gong and Jun Zhao Tags: Original research Source Type: research
Protection from contamination by 211At, an enigmatic but promising alpha-particle-emitting radionuclide
211At, a promising alpha-particle-emitting radionuclide, can easily volatilize and contaminate the environment. To safely manage this unique alpha-particle-emitting radionuclide, we investigated the permeability ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - June 6, 2022 Category: Radiology Authors: Kazunobu Ohnuki, Mitsuyoshi Yoshimoto, Hiromitsu Haba, Shino Manabe, Hiroki Takashima, Masahiro Yasunaga, Yasumasa Takenaka and Hirofumi Fujii Tags: Short communication Source Type: research
Method to determine the statistical technical variability of SUV metrics
The Standardized Uptake Value (SUV) Max, SUVMean, and SUVPeak are metrics used to quantify positron emission tomography (PET) images. In order to assess the significance of a change in these metrics for diagno... (Source: EJNMMI Physics)
Source: EJNMMI Physics - June 6, 2022 Category: Radiology Authors: Giulia M. R. De Luca and Jan B. A. Habraken Tags: Original research Source Type: research
Efficiency of 124I radioisotope production from natural and enriched tellurium dioxide using 124Te(p,xn)124I reaction
(Source: EJNMMI Physics)
Source: EJNMMI Physics - June 6, 2022 Category: Radiology Authors: Pawe ł Bzowski, Damian Borys, Kamil Gorczewski, Agnieszka Chmura, Kinga Daszewska, Izabela Gorczewska, Anna Kastelik-Hryniewiecka, Marcin Szydło, Andrea d’Amico and Maria Sokół Tags: Original research Source Type: research
Concept development of an on-chip PET system
Organs-on-Chips (OOCs), microdevices mimicking in vivo organs, find growing applications in disease modeling and drug discovery. With the increasing number of uses comes a strong demand for imaging capabilitie... (Source: EJNMMI Physics)
Source: EJNMMI Physics - May 19, 2022 Category: Radiology Authors: Christoph Clement, Gabriele Birindelli, Marco Pizzichemi, Fiammetta Pagano, Marianna Kruithof-De Julio, Sibylle Ziegler, Axel Rominger, Etiennette Auffray and Kuangyu Shi Tags: Original research Source Type: research
Patient-specific dosimetry adapted to variable number of SPECT/CT time-points per cycle for \(^{177}\)Lu-DOTATATE therapy
The number of SPECT/CT time-points is important for accurate patient dose estimation in peptide receptor radionuclide therapy. However, it may be limited by the patient ’s health and logistical reasons. Here, ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - May 16, 2022 Category: Radiology Authors: Laure Vergnaud, Anne-Laure Giraudet, Aur élie Moreau, Julien Salvadori, Alessio Imperiale, Thomas Baudier, Jean-Noël Badel and David Sarrut Tags: Original research Source Type: research
Clinical and phantom validation of a deep learning based denoising algorithm for F-18-FDG PET images from lower detection counting in comparison with the standard acquisition
PET/CT image quality is directly influenced by the F-18-FDG injected activity. The higher the injected activity, the less noise in the reconstructed images but the more radioactive staff exposition. A new FDA ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - May 11, 2022 Category: Radiology Authors: Gerald Bonardel, Axel Dupont, Pierre Decazes, Mathieu Queneau, Romain Modzelewski, Jeremy Coulot, Nicolas Le Calvez and S ébastien Hapdey Tags: Original research Source Type: research
Monte Carlo modelling of a compact CZT-based gamma camera with application to 177Lu imaging
Semiconductor gamma-camera systems based on cadmium zinc telluride (CZT) detectors present new challenges due to an energy-response that includes effects of low-energy tailing. In particular, such energy tails... (Source: EJNMMI Physics)
Source: EJNMMI Physics - May 8, 2022 Category: Radiology Authors: Daniel Roth, Erik Larsson, Michael Ljungberg and Katarina Sj ögreen Gleisner Tags: Original research Source Type: research
Feasibility of imaging synaptic density in the human spinal cord using [11C]UCB-J PET
Neuronal damage and synapse loss in the spinal cord (SC) have been implicated in spinal cord injury (SCI) and neurodegenerative disorders such as Amyotrophic Lateral Sclerosis (ALS). Current standards of diagn... (Source: EJNMMI Physics)
Source: EJNMMI Physics - May 3, 2022 Category: Radiology Authors: Samantha Rossano, Takuya Toyonaga, Jason Bini, Nabeel Nabulsi, Jim Ropchan, Zhengxin Cai, Yiyun Huang and Richard E. Carson Tags: Original research Source Type: research
