Development and validation of a prognostic nomogram model in locally advanced NSCLC based on metabolic features of PET/CT and hematological inflammatory indicators
We combined the metabolic features of 18F-FDG-PET/CT and hematological inflammatory indicators to establish a predictive model of the outcomes of patients with locally advanced non-small cell lung cancer (LA-NSCL... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 5, 2024 Category: Radiology Authors: Congjie Wang, Jian Fang, Tingshu Jiang, Shanliang Hu, Ping Wang, Xiuli Liu, Shenchun Zou and Jun Yang Tags: Original research Source Type: research
Correction: Feasibility study of a SiPM-fiber detector for non-invasive measurement of arterial input function for preclinical and clinical positron emission tomography
(Source: EJNMMI Physics)
Source: EJNMMI Physics - March 4, 2024 Category: Radiology Authors: Sara de Scals, Luis Mario Fraile, Jos é Manuel Udías, Laura Martínez Cortés, Marta Oteo, Miguel Ángel Morcillo, José Luis Carreras-Delgado, María Nieves Cabrera-Martín and Samuel España Tags: Correction Source Type: research
Effect of kilovoltage and quality reference mAs on CT-based attenuation correction in 177Lu SPECT/CT imaging: a phantom study
CT-based attenuation correction (CT-AC) plays a major role in accurate activity quantification by SPECT/CT imaging. However, the effect of kilovoltage peak (kVp) and quality-reference mAs (QRM) on the attenuat... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 26, 2024 Category: Radiology Authors: Maikol Salas-Ramirez, Julian Leube, Michael Lassmann and Johannes Tran-Gia Tags: Original research Source Type: research
Fit of biokinetic data in molecular radiotherapy: a machine learning approach
In literature are reported different analytical methods (AM) to choose the proper fit model and to fit data of the time-activity curve (TAC). On the other hand, Machine Learning algorithms (ML) are increasingl... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 22, 2024 Category: Radiology Authors: Davide Ciucci, Bartolomeo Cassano, Salvatore Donatiello, Federica Martire, Antonio Napolitano, Claudia Polito, Elena Solfaroli Camillocci, Gianluca Cervino, Ludovica Pungitore, Claudio Altini, Maria Felicia Villani, Milena Pizzoferro, Maria Carmen Gargane Tags: Original research Source Type: research
Kinetic 18F-FDG PET/CT imaging of hepatocellular carcinoma: a dual input four-compartment model
The endoplasmic reticulum plays an important role in glucose metabolism and has not been explored in the kinetic estimation of hepatocellular carcinoma (HCC) via 18F-fluoro-2-deoxy-d-glucose PET/CT. (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 22, 2024 Category: Radiology Authors: Tao Wang, Yinglei Deng, Sidan Wang, Jianfeng He and Shaobo Wang Tags: Original research Source Type: research
Quantitative calibration of Tb-161 SPECT/CT in view of personalised dosimetry assessment studies
Terbium-161 (161Tb)-based radionuclide therapy poses an alternative to current Lutetium-177 (177Lu) approaches with the additional benefit of secondary Auger and conversion electron emissions capable of deliverin... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 19, 2024 Category: Radiology Authors: Lachlan McIntosh, Price Jackson, Brittany Emmerson, James P. Buteau, Ramin Alipour, Grace Kong and Michael S. Hofman Tags: Original research Source Type: research
Phantom study and clinical application of total-body 18F-FDG PET/CT imaging: How to use small voxel imaging better?
Conventional PET/CT imaging reconstruction is typically performed using voxel size of 3.0 –4.0 mm in three axes. It is hypothesized that a smaller voxel sizes could improve the accuracy of small lesion detectio... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 15, 2024 Category: Radiology Authors: Chi Qi, Xiuli Sui, Haojun Yu, Siyang Wang, Yan Hu, Hongyan Sun, Xinlan Yang, Yihan Wang, Yun Zhou and Hongcheng Shi Tags: Original research Source Type: research
How to obtain the image-derived blood concentration from 89Zr-immuno-PET scans
PET scans using zirconium-89 labelled monoclonal antibodies (89Zr-mAbs), known as 89Zr-immuno-PET, are made to measure uptake in tumour and organ tissue. Uptake is related to the supply of 89Zr-mAbs in the blood.... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 7, 2024 Category: Radiology Authors: Jessica E. Wijngaarden, Amina Ahbari, Johanna E. E. Pouw, Henri N. J. M. Greuter, Idris Bahce, Gerben J. C. Zwezerijnen, Dani ëlle J. Vugts, Guus A. M. S. van Dongen, Ronald Boellaard, C. Willemien Menke-van der Houven van Oordt and Marc C. Huisman Tags: Original research Source Type: research
Anatomy-based correction of kidney PVE on \(^{177}\text{Lu}\) SPECT images
In peptide receptor radionuclide therapy (PRRT), accurate quantification of kidney activity on post-treatment SPECT images paves the way for patient-specific treatment. Due to the limited spatial resolution of... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 6, 2024 Category: Radiology Authors: Julien Salvadori, Oreste Allegrini, Thomas Opsommer, Josefina Carullo, David Sarrut, Clemence Porot, Florian Ritzenthaler, Philippe Meyer and Izzie-Jacques Namer Tags: Original research Source Type: research
Prediction of [177Lu]Lu-DOTA-TATE therapy response using the absorbed dose estimated from [177Lu]Lu-DOTA-TATE SPECT/CT in patients with metastatic neuroendocrine tumour
Peptide receptor radionuclide therapy (PRRT) with [177Lu]Lu-DOTA-TATE has shown efficacy in patients with metastatic neuroendocrine tumours (NETs). Personalised dosimetry is crucial to optimise treatment outcomes... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 5, 2024 Category: Radiology Authors: Sejin Ha, Yong-il Kim, Jungsu S. Oh, Changhoon Yoo, Baek-Yeol Ryoo and Jin-Sook Ryu Tags: Original research Source Type: research
Feasibility study of a SiPM-fiber detector for non-invasive measurement of arterial input function for preclinical and clinical positron emission tomography
Pharmacokinetic positron emission tomography (PET) studies rely on the measurement of the arterial input function (AIF), which represents the time-activity curve of the radiotracer concentration in the blood p... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 31, 2024 Category: Radiology Authors: Sara de Scals, Luis Mario Fraile, Jos é Manuel Udías, Laura Martínez Cortés, Marta Oteo, Miguel Ángel Morcillo, José Luis Carreras-Delgado, María Nieves Cabrera-Martín and Samuel España Tags: Original research Source Type: research
Validation of a discovery MI 4-ring model according to the NEMA NU 2-2018 standards: from Monte Carlo simulations to clinical-like reconstructions
We propose a comprehensive evaluation of a Discovery MI 4-ring (DMI) model, using a Monte Carlo simulator (GATE) and a clinical reconstruction software package (PET toolbox). The following performance characte... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 31, 2024 Category: Radiology Authors: Antoine Merlet, Beno ît Presles, Kuan-Hao Su, Julien Salvadori, Farzam Sayah, Hanieh Jozi, Alexandre Cochet and Jean-Marc Vrigneaud Tags: Original research Source Type: research
Evaluating a radiotherapy deep learning synthetic CT algorithm for PET-MR attenuation correction in the pelvis
Positron emission tomography –magnetic resonance (PET-MR) attenuation correction is challenging because the MR signal does not represent tissue density and conventional MR sequences cannot image bone. A novel z... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 29, 2024 Category: Radiology Authors: Jonathan J. Wyatt, Sandeep Kaushik, Cristina Cozzini, Rachel A. Pearson, George Petrides, Florian Wiesinger, Hazel M. McCallum and Ross J. Maxwell Tags: Original research Source Type: research
Simultaneous estimation of a model-derived input function for quantifying cerebral glucose metabolism with [18F]FDG PET
Quantification of the cerebral metabolic rate of glucose (CMRGlu) by dynamic [18F]FDG PET requires invasive arterial sampling. Alternatives to using an arterial input function (AIF) include the simultaneous estim... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 29, 2024 Category: Radiology Authors: Lucas Narciso, Graham Deller, Praveen Dassanayake, Linshan Liu, Samara Pinto, Udunna Anazodo, Andrea Soddu and Keith St Lawrence Tags: Original research Source Type: research
3D printed non-uniform anthropomorphic phantoms for quantitative SPECT
A 3D printing grid-based method was developed to construct anthropomorphic phantoms with non-uniform activity distributions, to be used for evaluation of quantitative SPECT images. The aims were to characteriz... (Source: EJNMMI Physics)
Source: EJNMMI Physics - January 22, 2024 Category: Radiology Authors: Lovisa Jessen, Johan Gustafsson, Michael Ljungberg, Selma Curkic-Kapidzic, Muris Imsirovic and Katarina Sj ögreen-Gleisner Tags: Original research Source Type: research
